Aliases for APOA5 Gene
Aliases for APOA5 Gene
External Ids for APOA5 Gene
- HGNC: 17288
- Entrez Gene: 116519
- Ensembl: ENSG00000110243
- OMIM: 606368
- UniProtKB: Q6Q788
Previous GeneCards Identifiers for APOA5 Gene
- GC11M119012
- GC11M118172
- GC11M116693
- GC11M116197
- GC11M116165
- GC11M116660
- GC11M112592
Summaries for APOA5 Gene
-
The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]
GeneCards Summary for APOA5 Gene
APOA5 (Apolipoprotein A5) is a Protein Coding gene. Diseases associated with APOA5 include Hyperchylomicronemia, Late-Onset and Hypertriglyceridemia. Among its related pathways are Statin Pathway and Lipoprotein metabolism. GO annotations related to this gene include enzyme binding and heparin binding.
UniProtKB/Swiss-Prot for APOA5 Gene
-
Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APOA5 Gene
Genomics for APOA5 Gene
Regulatory Elements for APOA5 Gene
- Transcription factor binding sites by QIAGEN in the APOA5 gene promoter:
Regulatory Element Products
Genomic Location for APOA5 Gene
- Chromosome:
- 11
- Start:
- 116,789,367 bp from pter
- End:
- 116,792,420 bp from pter
- Size:
- 3,054 bases
- Orientation:
- Minus strand
Genomic View for APOA5 Gene
- Cytogenetic band:
-
- 11q23.3 by Ensembl
- 11q23.3 by Entrez Gene
- 11q23.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for APOA5 Gene
Proteins for APOA5 Gene
-
Protein details for APOA5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6Q788-APOA5_HUMAN
- Recommended name:
- Apolipoprotein A-V
- Protein Accession:
- Q6Q788
- B0YIV9
- Q3MIK6
- Q6UWK9
- Q9UBJ3
Protein attributes for APOA5 Gene
- Size:
- 366 amino acids
- Molecular mass:
- 41213 Da
- Quaternary structure:
-
- Interacts with GPIHBP1.
- Miscellaneous:
-
- Induced in early phase of liver regeneration.
- SequenceCaution:
-
- Sequence=AAF25661.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAF25662.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAQ89109.1; Type=Erroneous termination; Positions=275; Note=Translated as Gln.; Evidence={ECO:0000305};
Protein Expression for APOA5 Gene
Post-translational modifications for APOA5 Gene
- Phosphorylated by FAM20C in the extracellular medium.
- Glycosylation at Ser80
- Modification sites at PhosphoSitePlus
Other Protein References for APOA5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for APOA5 (APOA5)
-
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- antibodies-online Antibodies for APOA5: See all 158
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Protein Products
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Cloud-Clone Corp. Proteins for APOA5
- antibodies-online Proteins for APOA5: See all 18
- Search antibodies-online for peptides
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No data available for DME Specific Peptides for APOA5 Gene
Domains & Families for APOA5 Gene
Gene Families for APOA5 Gene
- HGNC:
Suggested Antigen Peptide Sequences for APOA5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6Q788- Family:
-
- Belongs to the apolipoprotein A1/A4/E family.
Function for APOA5 Gene
Molecular function for APOA5 Gene
- UniProtKB/Swiss-Prot Function:
- Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and a inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate) (By similarity). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by PPARA agonists, which are used clinically to lower serum TG (such as fibrates).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005543 | phospholipid binding | IDA | 12810715 |
| GO:0008047 | enzyme activator activity | IDA | 16806135 |
| GO:0008201 | heparin binding | IDA | 15878877 |
| GO:0008289 | lipid binding | IDA | 12810715 |
| GO:0015485 | cholesterol binding | IBA | -- |
Phenotypes for APOA5 Gene
- MGI mutant phenotypes for APOA5:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for APOA5:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Increased shRNA abundance (Z-score > 2)
- Increased transferrin (TF) endocytosis
- Strongly decreased CFP-tsO45G cell surface transport
- Decreased free cholesterol
- Decreased shRNA abundance (Z-score < -2)
Animal Model Products
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Taconic Biosciences Mouse Models for APOA5
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-
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CRISPR Products
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miRNA for APOA5 Gene
- miRTarBase miRNAs that target APOA5
-
- hsa-mir-485-5p (MIRT438007)
- hsa-mir-4790-3p (MIRT711963)
- hsa-mir-4469 (MIRT711964)
- hsa-mir-6862-3p (MIRT711965)
- hsa-mir-6784-3p (MIRT711966)
- hsa-mir-4780 (MIRT711967)
- hsa-mir-4667-3p (MIRT711968)
- hsa-mir-1470 (MIRT711969)
- hsa-mir-3162-3p (MIRT711970)
- hsa-mir-3620-3p (MIRT711971)
- hsa-mir-6865-3p (MIRT711972)
miRNA Products
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
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Horizon Cell Lines for APOA5
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Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for APOA5 Gene
Localization for APOA5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for APOA5 Gene
- Secreted.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IDA | 18635818 |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0034361 | very-low-density lipoprotein particle | IDA | 15528295 |
Pathways & Interactions for APOA5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Lipoprotein metabolism | ||
| 2 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
| 3 | Statin Pathway |
.71
|
|
| 4 | Metabolism |
.37
|
|
| 5 | PPAR signaling pathway | ||
Pathways by source for APOA5 Gene
1 Cell Signaling Technology pathway for APOA5 Gene
2 BioSystems pathways for APOA5 Gene
1 PharmGKB pathway for APOA5 Gene
1 KEGG pathway for APOA5 Gene
Interacting Proteins for APOA5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006641 | triglyceride metabolic process | IMP | 12417525 |
| GO:0006695 | cholesterol biosynthetic process | IBA | -- |
| GO:0006810 | transport | IEA | -- |
| GO:0006869 | lipid transport | IDA | 15178420 |
| GO:0010873 | positive regulation of cholesterol esterification | IBA | -- |
No data available for SIGNOR curated interactions for APOA5 Gene
Drugs & Compounds for APOA5 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Fenofibrate | Approved | Pharma | 170 | |||
| atorvastatin | Approved | Pharma | Competitive, Inhibitor | 0 | ||
| Lovastatin | Approved, Investigational | Pharma | Competitive, Inhibitor | HMG-CoA reductase inhibitor, Potent HMG-CoA reductase inhibitor | 63 | |
| Simvastatin | Approved | Pharma | Competitive, Inhibitor | HMG-CoA reductase inhibitor | 519 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| PC(18:1(9Z)e/2:0) |
|
|
||||
| Phosphatidylcholines Group A |
|
68737-67-7 |
|
|||
| Phosphatidylcholines Group B |
|
88542-95-4 |
|
|||
| Triglycerides Group B |
|
555-45-3, 30719-27-8, 2190-24-1, 18641-57-1, 56933-26-7 | ||||
| Triglycerides Group C |
|
Transcripts for APOA5 Gene
mRNA/cDNA for APOA5 Gene
- (3) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (288) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for APOA5
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miRNA Products
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for APOA5 Gene
mRNA differential expression in normal tissues according to GTEx for APOA5 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for APOA5 Gene
NURSA nuclear receptor signaling pathways regulating expression of APOA5 Gene:
APOA5SOURCE GeneReport for Unigene cluster for APOA5 Gene:
Hs.283923mRNA Expression by UniProt/SwissProt for APOA5 Gene:
Q6Q788-APOA5_HUMANEvidence on tissue expression from TISSUES for APOA5 Gene
- Liver(4.6)
- Adrenal gland(2.6)
- Blood(2.5)
- Pancreas(2.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for APOA5 Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- digestive
- endocrine
- integumentary
- skeletal muscle
- ear
- heart
- duodenum
- intestine
- liver
- pancreas
- small intestine
- blood vessel
- skin
Primer Products
-
OriGene qPCR primer pairs for APOA5
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OriGene qPCR primer pairs and template standards for APOA5
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for APOA5 Gene
Orthologs for APOA5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | APOA5 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | APOA5 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | APOA5 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Apoa5 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Apoa5 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | APOA5 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | APOA5 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | apoa5 34 |
|
- Species where no ortholog for APOA5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for APOA5 Gene
No data available for Paralogs for APOA5 Gene
Variants for APOA5 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for APOA5 Gene
- APOA5_HUMAN-Q6Q788
- Three common alleles are known: allele APOA5*1, APOA5*2 and APOA5*3. The APOA5*2 haplotype, which consists of 3 non-coding SNPs, is present in approximately 16% of Caucasians and is associated with increased plasma triglyceride concentrations. APOA5*3 haplotype is defined by the rare Ser-19-Trp substitution. Together, the APOA5*2 and APOA5*3 haplotypes are found in 25 to 50% of African Americans, Hispanics, and Caucasians.
| SNP ID | Clin | Chr 11 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs121917821 | Pathogenic | 116,790,814(-) | TGGAG(C/T)AGGTG | upstream-variant-2KB, reference, stop-gained | |
| rs2075291 | other | 116,790,676(-) | ACACC(A/G/T)GCCGC | upstream-variant-2KB, reference, missense | |
| rs2266788 | other | 116,789,970(-) | CTGCA(C/T)ATCCA | upstream-variant-2KB, utr-variant-3-prime | |
| rs3135506 | other | 116,791,691(+) | TGGCC(A/C/G)AAAAC | reference, missense | |
| rs1000014881 | -- | 116,793,828(+) | AGAAG(A/G)ACATG | upstream-variant-2KB |
Relevant External Links for APOA5 Gene
Disorders for APOA5 Gene
(10) MalaCards diseases for APOA5 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hyperchylomicronemia, late-onset |
|
|
| hypertriglyceridemia |
|
|
| coronary artery disease |
|
|
| artery disease |
|
|
| hyperlipidemia, familial combined |
|
UniProtKB/Swiss-Prot
APOA5_HUMAN- Hyperlipoproteinemia 5 (HLPP5) [MIM:144650]: Characterized by increased amounts of chylomicrons and very low density lipoprotein (VLDL) and decreased low density lipoprotein (LDL) and high density lipoprotein (HDL) in the plasma after a fast. Numerous conditions cause this phenotype, including insulin-dependent diabetes mellitus, contraceptive steroids, alcohol abuse, and glycogen storage disease type 1A (GSD1A). {ECO:0000269 PubMed:16200213}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Hypertriglyceridemia, familial (FHTR) [MIM:145750]: A common inherited disorder in which the concentration of very low density lipoprotein (VLDL) is elevated in the plasma. This leads to increased risk of heart disease, obesity, and pancreatitis. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
Relevant External Links for APOA5
No data available for Genatlas for APOA5 Gene
Publications for APOA5 Gene
- Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. (PMID: 12417524) Pennacchio L.A. … Cohen J.C. (Hum. Mol. Genet. 2002) 3 4 22 46 64
- An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. (PMID: 11588264) Pennacchio L.A. … Rubin E.M. (Science 2001) 2 3 4 22 64
- Apolipoprotein A5 and lipoprotein lipase interact to modulate anthropometric measures in Hispanics of Caribbean origin. (PMID: 19629056) Smith C.E. … OrdovA!s J.M. (Obesity (Silver Spring) 2010) 3 22 46 64
- Association of APOA5 and APOC3 gene polymorphisms with plasma apolipoprotein A5 level in patients with metabolic syndrome. (PMID: 19932084) Niculescu L.S. … Sima A.V. (Biochem. Biophys. Res. Commun. 2010) 3 22 46 64
- Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study. (PMID: 20429872) Ariza M.J. … GonzA!lez-Santos P. (BMC Med. Genet. 2010) 3 22 46 64
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- GenScript Custom Peptide Services for APOA5
- Cell Signaling Technology (CST) Antibodies for APOA5 (APOA5)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for APOA5
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for APOA5
- Novus Biologicals proteins and lysates for APOA5
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for APOA5
- Cloud-Clone Corp. Antibodies for APOA5
- Cloud-Clone Corp. Proteins for APOA5
- Cloud-Clone Corp Assay Kits for APOA5
- Taconic Biosciences Mouse Models for APOA5
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for APOA5: See all 158
- antibodies-online Kits for APOA5: See all 43
- antibodies-online Proteins for APOA5: See all 18
- Search antibodies-online for peptides
- GeneTex APOA5 antibody for APOA5
- Search GeneTex for Proteins for APOA5
- ViGene Biosciences adenoviral particle packaged cDNA for APOA5 gene
- ViGene Biosciences lentiviral particle packaged cDNA for APOA5 gene
- ViGene Biosciences ready-to-package AAV shRNAs for APOA5 gene
- Search ViGene Biosciences for APOA5
- Santa Cruz Biotechnology (SCBT) Antibodies for APOA5
- Search Santa Cruz Biotechnology (SCBT) for APOA5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for APOA5
- Custom Antibody ServicesProSci Antibodies for APOA5
- Search for APOA5 Proteins at ProSci
- Horizon Cell Lines for APOA5
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOA5
- VectorBuilder custom plasmid, inducible vectors for APOA5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOA5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for APOA5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




