Aliases for APOA2 Gene
External Ids for APOA2 Gene
Previous GeneCards Identifiers for APOA2 Gene
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for APOA2 Gene
APOA2 (Apolipoprotein A2) is a Protein Coding gene. Diseases associated with APOA2 include Hypercholesterolemia, Familial and Aapoaii Amyloidosis. Among its related pathways are Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) and Metabolism. GO annotations related to this gene include protein homodimerization activity and lipid binding.
UniProtKB/Swiss-Prot for APOA2 Gene
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.