Aliases for APOA2 Gene
External Ids for APOA2 Gene
Previous GeneCards Identifiers for APOA2 Gene
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for APOA2 Gene
APOA2 (Apolipoprotein A2) is a Protein Coding gene. Diseases associated with APOA2 include hypercholesterolemia, familial and aapoaii amyloidosis. Among its related pathways are PPAR signaling pathway and Lipoprotein metabolism. GO annotations related to this gene include protein homodimerization activity and lipid binding.
UniProtKB/Swiss-Prot for APOA2 Gene
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.