Aliases for APOA2 Gene
Aliases for APOA2 Gene
External Ids for APOA2 Gene
- HGNC: 601
- Entrez Gene: 336
- Ensembl: ENSG00000158874
- OMIM: 107670
- UniProtKB: P02652
Previous GeneCards Identifiers for APOA2 Gene
- GC01M158903
- GC01M156924
- GC01M157969
- GC01M158408
- GC01M158005
- GC01M159458
- GC01M132549
Summaries for APOA2 Gene
-
This gene encodes apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for APOA2 Gene
APOA2 (Apolipoprotein A2) is a Protein Coding gene. Diseases associated with APOA2 include Hypercholesterolemia, Familial and Aapoaii Amyloidosis. Among its related pathways are Metabolism of fat-soluble vitamins and Statin Pathway. GO annotations related to this gene include protein homodimerization activity and lipid binding.
UniProtKB/Swiss-Prot for APOA2 Gene
-
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APOA2 Gene
Genomics for APOA2 Gene
Regulatory Elements for APOA2 Gene
- Transcription factor binding sites by QIAGEN in the APOA2 gene promoter:
Regulatory Element Products
Genomic Location for APOA2 Gene
- Chromosome:
- 1
- Start:
- 161,222,292 bp from pter
- End:
- 161,223,631 bp from pter
- Size:
- 1,340 bases
- Orientation:
- Minus strand
Genomic View for APOA2 Gene
- Cytogenetic band:
-
- 1q23.3 by Ensembl
- 1q23.3 by Entrez Gene
- 1q23.3 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for APOA2 Gene
Proteins for APOA2 Gene
-
Protein details for APOA2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P02652-APOA2_HUMAN
- Recommended name:
- Apolipoprotein A-II
- Protein Accession:
- P02652
- B2R524
Protein attributes for APOA2 Gene
- Size:
- 100 amino acids
- Molecular mass:
- 11175 Da
- Quaternary structure:
-
- Monomer. Homodimer; disulfide-linked. Also forms a disulfide-linked heterodimer with APOD. Interacts with HCV core protein. Interacts with APOA1BP and NDRG1.
Protein Expression for APOA2 Gene
Post-translational modifications for APOA2 Gene
- Apolipoprotein A-II is O-glycosylated.
- Phosphorylation sites are present in the extracellular medium.
- Glycosylation at Thr42
- Modification sites at PhosphoSitePlus
Other Protein References for APOA2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for APOA2
- R&D Systems Antibodies for APOA2 (Apolipoprotein A-II/ApoA2)
-
Custom Antibody ServicesOriGene Antibodies for APOA2
- Novus Biologicals Antibodies for APOA2
-
Cloud-Clone Corp. Antibodies for APOA2
- Invitrogen Antibodies for APOA2
- antibodies-online Antibodies for APOA2: See all 176
- GeneTex APOA2 antibody for APOA2
-
Santa Cruz Biotechnology (SCBT) Antibodies for APOA2
Protein Products
- EMD Millipore Purified and/or Recombinant APOA2 Protein
-
OriGene Purified Proteins for APOA2
- Search Origene for MassSpec and Protein Over-expression Lysates for APOA2
- Origene Custom Protein Services for APOA2
-
Cloud-Clone Corp. Proteins for APOA2
- antibodies-online Proteins for APOA2: See all 29
- Search antibodies-online for peptides
- Search GeneTex for Proteins for APOA2
-
ProSci Proteins for APOA2
Assay Products
-
Cloud-Clone Corp Assay Kits for APOA2
- antibodies-online Kits for APOA2: See all 55
-
Abcam assays for APOA2
No data available for DME Specific Peptides for APOA2 Gene
Domains & Families for APOA2 Gene
Gene Families for APOA2 Gene
- HGNC:
Protein Domains for APOA2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for APOA2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P02652- Family:
-
- Belongs to the apolipoprotein A2 family.
Function for APOA2 Gene
Molecular function for APOA2 Gene
- GENATLAS Biochemistry:
- apolipoprotein A-II,associated with HDL (see TSG1M)
- UniProtKB/Swiss-Prot Function:
- May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005319 | lipid transporter activity | IDA | 1606170 |
| GO:0005515 | protein binding | IPI | 11991719 |
| GO:0005543 | phospholipid binding | IDA | 218942 |
| GO:0008035 | high-density lipoprotein particle binding | IEA | -- |
| GO:0008289 | lipid binding | IEA,IDA | 14967812 |
Phenotypes for APOA2 Gene
- MGI mutant phenotypes for APOA2:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for APOA2:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- Decreased NF-kappaB reporter expression
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased transferrin (TF) endocytosis
- Increased G1 DNA content
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Synthetic lethal with vaccinia virus (VACV) infection
- Decreased viability of wild-type and TP53 knockout cells
Animal Models for APOA2 Gene
- MGI Knock Outs for APOA2:
-
- Apoa2 tm1Bres
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOA2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for APOA2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for APOA2 gene
- Search ViGene Biosciences for APOA2
CRISPR Products
-
OriGene CRISPR knockouts for APOA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for APOA2
- GenScript: Design CRISPR guide RNA sequences for APOA2
miRNA Products
- Search ViGene Biosciences for APOA2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for APOA2
- Browse OriGene Inhibitory RNA Products For APOA2
-
ViGene Biosciences ready-to-package AAV shRNAs for APOA2 gene
Clone Products
-
OriGene ORF clones in human for APOA2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for APOA2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for APOA2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOA2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for APOA2
-
ViGene Biosciences adenoviral particle packaged cDNA for APOA2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for APOA2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for APOA2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for APOA2 Gene
Localization for APOA2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for APOA2 Gene
- Secreted.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,TAS | -- |
| GO:0005615 | extracellular space | IEA | -- |
| GO:0005769 | early endosome | TAS | -- |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for APOA2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Lipoprotein metabolism | ||
| 2 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||
| 3 | Metabolism of fat-soluble vitamins | ||
| 4 | Metabolism |
.37
|
|
| 5 | Statin Pathway |
.71
|
|
Pathways by source for APOA2 Gene
3 BioSystems pathways for APOA2 Gene
1 KEGG pathway for APOA2 Gene
1 GeneGo (Thomson Reuters) pathway for APOA2 Gene
Interacting Proteins for APOA2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001523 | retinoid metabolic process | TAS | -- |
| GO:0002526 | acute inflammatory response | IEA | -- |
| GO:0002740 | negative regulation of cytokine secretion involved in immune response | IDA | 12458630 |
| GO:0006641 | triglyceride metabolic process | TAS | 11551871 |
| GO:0006656 | phosphatidylcholine biosynthetic process | IDA | 14967812 |
No data available for SIGNOR curated interactions for APOA2 Gene
Transcripts for APOA2 Gene
mRNA/cDNA for APOA2 Gene
- (1) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (591) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for APOA2
-
Santa Cruz Biotechnology (SCBT) CRISPR for APOA2
- GenScript: Design CRISPR guide RNA sequences for APOA2
miRNA Products
- Search ViGene Biosciences for APOA2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for APOA2
- Browse OriGene Inhibitory RNA Products For APOA2
-
ViGene Biosciences ready-to-package AAV shRNAs for APOA2 gene
Clone Products
-
OriGene ORF clones in human for APOA2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for APOA2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for APOA2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOA2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||
| SP3: | - | ||||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||||
| SP5: | |||||||||||||||||||||
| SP6: | - | - | - |
Expression for APOA2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- NULL (Uncategorized)
- Liver (Hepatobiliary System)
- Inner Cell Mass (Early Embryonic Tissues)
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
- Endoderm (Gastrulation Derivatives)
- Heart (Cardiovascular System)
- Primitive Streak (Early Embryonic Tissues)
-
Spleen (Hematopoietic System)
-
Lung (Respiratory System)
mRNA differential expression in normal tissues according to GTEx for APOA2 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for APOA2 Gene
NURSA nuclear receptor signaling pathways regulating expression of APOA2 Gene:
APOA2SOURCE GeneReport for Unigene cluster for APOA2 Gene:
Hs.237658mRNA Expression by UniProt/SwissProt for APOA2 Gene:
P02652-APOA2_HUMANEvidence on tissue expression from TISSUES for APOA2 Gene
- Liver(5)
- Muscle(4.3)
- Bone marrow(4)
- Spleen(3.6)
- Blood(3.1)
- Heart(2.2)
Primer Products
-
OriGene qPCR primer pairs for APOA2
-
OriGene qPCR primer pairs and template standards for APOA2
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for APOA2 Gene
Orthologs for APOA2 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | APOA2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | APOA2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | APOA2 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Apoa2 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Apoa2 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | APOA2 35 |
|
OneToOne |
- Species where no ortholog for APOA2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for APOA2 Gene
No data available for Paralogs for APOA2 Gene
Variants for APOA2 Gene
Polymorphic Variants from UniProtKB/Swiss-Prot for APOA2 Gene
- APOA2_HUMAN-P02652
- A homozygous transition at position 1 of intron 3 of APOA2 results in deficiency of apolipoprotein A-II, without significant influence either on lipid and lipoprotein profiles or on the occurrence of coronary artery disease [MIM:107670].
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs6413453 | Likely benign | 161,222,526(-) | CCTAT(C/T)CAGGT | intron-variant | |
| rs138452270 | Uncertain significance | 161,222,465(+) | AGTTC(C/T)GTTCC | reference, synonymous-codon | |
| rs141599125 | Uncertain significance | 161,223,056(+) | CACAC(-/CACACA)TCTTT | intron-variant | |
| rs201433891 | Uncertain significance | 161,223,422(+) | GAGGG(A/C/G/T)GGCCT | utr-variant-5-prime | |
| rs3813625 | Uncertain significance | 161,223,617(+) | CCTTG(A/G)TGTCT | utr-variant-5-prime |
Relevant External Links for APOA2 Gene
No data available for Structural Variations from Database of Genomic Variants (DGV) for APOA2 Gene
Disorders for APOA2 Gene
(23) MalaCards diseases for APOA2 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypercholesterolemia, familial |
|
|
| aapoaii amyloidosis |
|
|
| apolipoprotein a-ii deficiency |
|
|
| norum disease |
|
|
| fish-eye disease |
|
Genatlas disease for APOA2 Gene
Relevant External Links for APOA2
No data available for UniProtKB/Swiss-Prot for APOA2 Gene
Publications for APOA2 Gene
- APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations. (PMID: 19901143) Corella D. … Ordovas J.M. (Arch. Intern. Med. 2009) 3 22 46 64
- Characterization of specifically oxidized apolipoproteins in mildly oxidized high density lipoprotein. (PMID: 12576517) Pankhurst G. … Stocker R. (J. Lipid Res. 2003) 3 4 22 64
- Sequence polymorphism at the human apolipoprotein AII gene (APOA2): unexpected deficit of variation in an African-American sample. (PMID: 12136239) Fullerton S.M. … Nickerson D.A. (Hum. Genet. 2002) 3 4 46 64
- A splice-junction mutation responsible for familial apolipoprotein A- II deficiency. (PMID: 2107739) Deeb S.S. … Albers J.J. (Am. J. Hum. Genet. 1990) 3 4 22 64
- Expression and purification of recombinant human apolipoprotein A-II in Pichia pastoris. (PMID: 24116940) Su M. … Wang D. (Assay Drug Dev Technol 2013) 3 4 64
Products for APOA2 Gene
- Browse Small Molecules at EMD Millipore
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for APOA2
- EMD Millipore Purified and/or Recombinant APOA2 Protein
- Browse Kits and Assays available from EMD Millipore
- EMD Millipore genomic analysis products
- R&D Systems Antibodies for APOA2 (Apolipoprotein A-II/ApoA2)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
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- Browse ELISAs
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- Custom Antibody ServicesOriGene Antibodies for APOA2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for APOA2
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- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for APOA2
- Browse OriGene Inhibitory RNA Products For APOA2
- OriGene qPCR primer pairs and template standards for APOA2
- OriGene qPCR primer pairs for APOA2
- OriGene CRISPR knockouts for APOA2
- OriGene ORF clones in human for APOA2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For APOA2
- GenScript: Next-day shipping cDNA ORF clone for APOA2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for APOA2
- GenScript Custom Assay Services for APOA2
- GenScript Custom overexpressing Cell Line Services for APOA2
- GenScript: Design CRISPR guide RNA sequences for APOA2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Plasmid Preparation
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- Sino Biological Human cDNA Clone for APOA2
- Browse Sino Biological Cell Lysates
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for APOA2
- Novus Biologicals proteins and lysates for APOA2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for APOA2
- Cloud-Clone Corp. Proteins for APOA2
- Cloud-Clone Corp Assay Kits for APOA2
- antibodies-online Antibodies for APOA2: See all 176
- antibodies-online Kits for APOA2: See all 55
- antibodies-online Proteins for APOA2: See all 29
- Search antibodies-online for peptides
- GeneTex APOA2 antibody for APOA2
- Search GeneTex for Proteins for APOA2
- ViGene Biosciences adenoviral particle packaged cDNA for APOA2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for APOA2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for APOA2 gene
- Search ViGene Biosciences for APOA2
- Santa Cruz Biotechnology (SCBT) Antibodies for APOA2
- Search Santa Cruz Biotechnology (SCBT) for APOA2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for APOA2
- Search for APOA2 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for APOA2
- Horizon Cell Lines for APOA2
- Cyagen custom Knockout/knockin (KOKI) mouse models for APOA2
- VectorBuilder custom plasmid, inducible vectors for APOA2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for APOA2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for APOA2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer




