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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APOA1BP Gene

protein-coding   GIFtS: 54
GCID: GC01P156561

apolipoprotein A-I binding protein
 Explore 6 diseases affiliated with
APOA1BP via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for APOA1BP    

Aliases
for APOA1BP gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Apolipoprotein A-I Binding Protein1 2     MGC1191441
AIBP1 2 3     MGC1191451
YJEFN11 2 3     ApoA-I Binding Protein2
Apolipoprotein A-I-Binding Protein2 3     NAD(P)H-Hydrate Epimerase2
YjeF N-Terminal Domain-Containing Protein 12 3     YjeF_N13
AI-BP2 3     EC 5.1.99.63
NAD(P)HX Epimerase2 3     YjeF_N13
MGC1191431     

External Ids:    HGNC: 184531   Entrez Gene: 1282402   Ensembl: ENSG000001633827   OMIM: 6088625   UniProtKB: Q8NCW53   

Export aliases for APOA1BP gene to outside databases

Previous GC identifers: GC01P154430 GC01P152326 GC01P153339 GC01P153778 GC01P153374 GC01P154828 GC01P127919


Summaries
for APOA1BP gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for APOA1BP:
The product of this gene interacts with apolipoprotein A-I (apoA-I), the major apolipoprotein of high-density
lipoproteins (HDLs). It is secreted into some bodily fluids, and its synthesis and secretion are stimulated in vitro
by incubating cells with apoA-I. The human genome contains related pseudogenes. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: NNRE_HUMAN, Q8NCW5
Function: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of
enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow
the repair of both epimers of NAD(P)HX (By similarity)




Genomic Views
for APOA1BP gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APOA1BP gene promoter:
         USF1   STAT1   RFX1   AML1a   Pax-6   STAT1beta   STAT1alpha   CREB   deltaCREB   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: APOA1BP promoter sequence
   Search SABiosciences Chromatin IP Primers for APOA1BP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APOA1BP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21   Ensembl cytogenetic band:  1q23.1   HGNC cytogenetic band: 1q21

APOA1BP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APOA1BP gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P156561:  view genomic region     (about GC identifiers)

Start:
 156,561,554 bp from pter      End:
 156,564,091 bp from pter
Size:
 2,538 bases      Orientation:
 plus strand

Proteins
for APOA1BP gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NNRE_HUMAN, Q8NCW5 (See protein sequence)
Recommended Name: NAD(P)H-hydrate epimerase precursor  
Size: 288 amino acids; 31675 Da
Cofactor: Binds 1 potassium ion per subunit (By similarity)
Subunit: Homodimer (By similarity). Interacts with APOA1 and APOA2
Subcellular location: Mitochondrion (By similarity). Secreted. Note=In sperm, secretion gradually increases during
capacitation (By similarity)
Secondary accessions: B4DGY3 Q496C6 Q5T3I2
Alternative splicing: 2 isoforms:  Q8NCW5-1   Q8NCW5-2   

Explore the universe of human proteins at neXtProt for APOA1BP: NX_Q8NCW5

Post-translational modifications:

  • Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8NCW5

    • APOA1BP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_658985.2  
    ENSEMBL proteins: 
     ENSP00000357217   ENSP00000357218   ENSP00000357216  

    Human Recombinant Protein Products: 
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    Novus Biologicals APOA1BP Proteins
    Novus Biologicals APOA1BP Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for APOA1BP

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IDA11991719
    GO:0005615extracellular space ISS--
    GO:0005739mitochondrion IEA--
    GO:0019861flagellum ----
    GO:0044297cell body IEA--


    APOA1BP for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for APOA1BP gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    APOA1BP for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR004443 YjeF_N_dom
     IPR026600 NnrE/AIBP

    Graphical View of Domain Structure for InterPro Entry Q8NCW5

    ProtoNet protein and cluster: Q8NCW5

    1 Blocks protein family: IPB004443 YjeF-related protein

    UniProtKB/Swiss-Prot: NNRE_HUMAN, Q8NCW5
    Similarity: Belongs to the nnrE/AIBP family
    Similarity: Contains 1 YjeF N-terminal domain


    Function
    for APOA1BP gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NNRE_HUMAN, Q8NCW5
    Function: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of
    enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow
    the repair of both epimers of NAD(P)HX (By similarity)
    Catalytic activity: (6R)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide =
    (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide
    Catalytic activity: (6R)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate =
    (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate

    Enzyme Number (IUBMB): EC 5.1.99.61

    miRNA
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    hsa-miR-1224-3p hsa-miR-1264
    SwitchGear 3'UTR luciferase reporter plasmid: APOA1BP 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: APOA1BP
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0005515protein binding IPI11991719
    GO:0016853isomerase activity ----
    GO:0042803protein homodimerization activity IEA--
    GO:0046872metal ion binding IEA--


    APOA1BP for ontologies           About GeneDecksing



    Pathways & Interactions
    for APOA1BP gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1NADH repair
    		NADH repair1.00


    1 BioSystems Pathway for APOA1BP 
        NADH repair


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APOA1BP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/22 Interacting proteins for APOA1BP (Q8NCW52, 3 ENSP000003572184) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8260702 I2D: score=2 
    H2AFXP161043, ENSP000003643104I2D: score=2 STRING: ENSP00000364310
    ALG6Q9Y6723, ENSP000003601494I2D: score=1 STRING: ENSP00000360149
    CARKDQ8IW453, ENSP000003119844I2D: score=1 STRING: ENSP00000311984
    APOA1P026473, ENSP000002368504I2D: score=2 STRING: ENSP00000236850
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0051289protein homotetramerization IEA--


    APOA1BP for ontologies           About GeneDecksing



    Drugs & Compounds
    for APOA1BP gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APOA1BP
    Search CenterWatch for drugs/clinical trials and news about APOA1BP / NNRE 

    Transcripts
    for APOA1BP gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for APOA1BP gene: 
    NM_144772.2  

    Unigene Cluster for APOA1BP:

    Apolipoprotein A-I binding protein
    Hs.528320  [show with all ESTs]
    Unigene Representative Sequence: AK123518
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368234 ENST00000368235(uc001fph.3 uc001fpi.3 uc001fpk.3 uc010php.1)
    ENST00000368233 ENST00000467374 ENST00000488840

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat APOA1BP
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate APOA1BP:
    hsa-miR-1224-3p hsa-miR-1264
    SwitchGear 3'UTR luciferase reporter plasmid: APOA1BP 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for APOA1BP (see all 7)
    OriGene shRNA RFP: APOA1BP
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APOA1BP
    Clone
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    GenScript: all cDNA clones in your preferred vector: APOA1BP (NM_144772)
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APOA1BP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APOA1BP

    Additional cDNA sequence: 

    AJ315849.1 AK123518.1 AK294835.1 AK298222.1 AK316083.1 BC056917.1 BC100931.1 BC100932.1 
    BC100933.1 BC100934.2 

    15 DOTS entries:

    DT.85105628  DT.114776  DT.100781784  DT.40109623  DT.101983816  DT.121345389  DT.95191151  DT.100698079 
    DT.100781786  DT.95191136  DT.95191137  DT.95191149  DT.121345338  DT.92435093  DT.434968 

    24/210 AceView cDNA sequences (see all 210):

    CR620453 AA130163 BM826821 CB123166 BM833895 CR606563 CR606473 BE781125 
    CR593423 AA448118 BM700595 AA099926 CR597550 BQ694356 NM_144772 BM805765 
    BF981101 BG751275 BU626278 BG338957 AK123518 BV187293 BG032263 BM977725 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for APOA1BP (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c
    SP1:                                                        -     -           -     -                     
    SP2:                                                        -                 -     -                     
    SP3:                                                        -                 -     -                     
    SP4:                                                        -                                             
    SP5:                                                        -                 -     -                     


    ECgene alternative splicing isoforms for APOA1BP

    Expression
    for APOA1BP gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APOA1BP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACGATTGATG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    APOA1BP expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FolliclePrimary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See APOA1BP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APOA1BP

    SOURCE GeneReport for Unigene cluster: Hs.528320

    UniProtKB/Swiss-Prot: NNRE_HUMAN, Q8NCW5
    Tissue specificity: Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal
    fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level)

        SABiosciences Custom PCR Arrays for APOA1BP
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    In Situ
    Assay Products:     
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    Orthologs
    for APOA1BP gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for APOA1BP gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves APOA1BP6
    		 --
    		 68(a)
    		 1 ↔ 1
    		 Un(50133428-50134962)
    lizard
    (Anolis carolinensis)    		 Reptilia APOA1BP6
    		 --
    		 67(a)
    		 1 ↔ 1
    		 GL345062.1(1975-7741)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.168012 Xenopus laevis transcribed sequence with weak similarity more 75.91(n)    BX853119.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BQ262511.12   -- 75.73(n)    BQ262511.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG29741 , 3 CG29741 53(a)3
    61.36(n)1
    61.95(a)1    		   9B13
    319441  NM_132376.21  NP_572604.21 
    worm
    (Caenorhabditis elegans)    		 Secernentea Y18D10A.33
    CELE_Y18D10A.31    		 Protein Y18D10A.31 44(a)3
    51.77(n)1
    47.79(a)1    		   I(12818221-12823693)3
    1894721  NM_060840.11  NP_493241.11 
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes (YNL200C)4
    YNL200C1    		 Putative protein of unknown function; the authentic, more4
    hypothetical protein1    		 47.07(n)1
    42.49(a)1    		   14(264453-263713)4
    8555211, 4  NP_014199.11, 4 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons PPOX1 pyridoxin (pyrodoxamine) 5'-phosphate oxidase 51.82(n)
    54.15(a)    		   835061  NM_124376.3  NP_568717.2 
    rice
    (Oryza sativa)    		 Liliopsida Os.167852 Oryza sativa (japonica cultivar-group) cDNA clone0 more 72.31(n)    AK099380.1 


    ENSEMBL Gene Tree for APOA1BP (if available)
    TreeFam Gene Tree for APOA1BP (if available) 

    Paralogs
    for APOA1BP gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for APOA1BP gene
    YJEFN32  
    1 SIMAP similar gene for APOA1BP using alignment to 5 protein entries:     NNRE_HUMAN (see all proteins):
    YJEFN3

    APOA1BP for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for APOA1BP
    PGOHUM00000234538 PGOHUM00000235857


    Genomic Variants
    for APOA1BP gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/102 NCBI SNPs in APOA1BP are shown (see all 102)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1429033161,2
    		--156559604(+) GAGGTC/TAGAGC 1 -- us2k10--------
    rs1862058081,2
    		--156559612(+) AGCACC/TCTTCT 1 -- us2k10--------
    rs1412550021,2
    		C,--156559641(+) TTTTC-/TTTTTTTT 1 -- us2k10--------
    rs1905790821,2
    		--156559658(+) TTTGGG/TGGGGG 1 -- us2k10--------
    rs101275511,2
    		C,F,--156559659(+) TTGGGG/AGGGGG 1 -- us2k1 tfbs3 trp38Minor allele frequency- A:0.45NA WA EA 368
    rs596355581,2
    		C,--156559660(+) TGGGGG/TGGGGG 1 -- us2k14Minor allele frequency- T:0.24WA NA EA 360
    rs1466372481,2
    		--156559701(+) AGTGCA/GGTGGC 1 -- us2k10--------
    rs1414774621,2
    		--156559814(+) GCTAAC/TTTTTT 1 -- us2k10--------
    rs1828213391,2
    		--156560135(+) GCCAGA/GCTGGT 1 -- us2k10--------
    rs1871735961,2
    		--156560146(+) CTTGAA/TCTCCT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for APOA1BP (156561554 - 156564091 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for APOA1BP: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for APOA1BP gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    APOA1BP for disorders           About GeneDecksing

    OMIM gene information: 608862    OMIM disorders: --

    6 diseases for APOA1BP:    About MalaCards
    coronary heart disease    hepatocellular carcinoma    cholesterol    carcinoma
    malaria    sepsis

    Human Genome Epidemiology (HuGE) Navigator: APOA1BP (3 documents)

    Export disorders for APOA1BP gene to outside databases

    Publications
    for APOA1BP gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APOA1BP gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with APOA1BP)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel apolipoprotein A-I-binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I. (PubMed id 11991719)1, 2, 3, 9 Ritter M....Schmitz G. (2002)
    2. ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and hYjeF_N3 comprise the YjeF_N domain protein family in humans with a role in spermiogenesis and oogenesis. (PubMed id 17533573)1, 3, 9 Rudolph C.... Schmitz G. (2007)
    3. Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1 Jugessur A....Murray J.C. (2010)
    9. Proteomic dissection of cell type-specific H2AX-inter acting protein complex associated with hepatocellular carcinoma. (PubMed id 20000738)1 Yang X....Chen X. (2010)
    10. Common genetic variation in multiple metabolic pathwa ys influences susceptibility to low HDL-cholesterol and coronary heart disease. (PubMed id 20855565)1 Peloso G.M....Brousseau M.E. (2010)

    External Searches for APOA1BP gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing APOA1BP gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 128240 HGNC: 18453 AceView: APOA1BP Ensembl:ENSG00000163382 euGenes: HUgn128240
    ECgene: APOA1BP H-InvDB: APOA1BP

    Other Databases showing APOA1BP gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing APOA1BP gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APOA1BP Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for APOA1BP gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for APOA1BP gene:
    Search GeneIP for patents involving APOA1BP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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