Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms of Use
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
GeneCards Plus
- Premium Tools
  
  Learn more

Set Analyses:

VarElect

Advanced Search

APMAP Gene

protein-coding GIFtS: 46
GCID: GC20M024945

Adipocyte Plasma Membrane Associated Protein

(Previous name: chromosome 20 open reading frame 3)
(Previous symbol: C20orf3)

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

TryGeneCards Plus

Aliases
Adipocyte Plasma Membrane Associated Protein¹ ²
C20orf3¹ ² ³
Protein BSCv² ³
Chromosome 20 Open Reading Frame 3¹
BSCv²
Adipocyte Plasma Membrane-Associated Protein²

External Ids:	HGNC: 13238¹	Entrez Gene: 57136²	Ensembl: ENSG00000101474⁷	UniProtKB: Q9HDC9³

Export aliases for APMAP gene to outside databases

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for APMAP Gene:

APMAP (adipocyte plasma membrane associated protein) is a protein-coding gene. Diseases associated with APMAP include polycystic ovary syndrome, and colorectal cancer. GO annotations related to this gene include strictosidine synthase activity and arylesterase activity.

UniProtKB/Swiss-Prot: APMAP_HUMAN, Q9HDC9

Function: Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in

adipocyte differentiation

Gene Wiki entry for APMAP (C20orf3) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus

RefSeq DNA sequence:

NC_000020.11 NT_011387.9 NC_018931.2

Regulatory elements:

Search for regulatory transcription factor binding sites for APMAP
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: APMAP promoter sequence

Search Chromatin IP Primers for APMAP

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat APMAP

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.2 Ensembl cytogenetic band: 20p11.21 HGNC cytogenetic band: 20p11.2

APMAP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APMAP gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M024945: view genomic region (about GC identifiers)

Start:	24,943,561 bp from pter	End:	24,973,615 bp from pter
Size:	30,055 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: APMAP_HUMAN, Q9HDC9 (See protein sequence)

Recommended Name: Adipocyte plasma membrane-associated protein

Size: 416 amino acids; 46480 Da

Sequence caution: Sequence=AAQ89435.1; Type=Erroneous initiation; Sequence=BAB11885.1; Type=Erroneous initiation;

Sequence=BAB15253.1; Type=Erroneous initiation; Sequence=BAB15578.1; Type=Erroneous initiation;

Secondary accessions: A8K514 B4DXG1 Q6UVZ8 Q9GZS8 Q9NUB2

Alternative splicing: 2 isoforms: Q9HDC9-1 Q9HDC9-2

Explore the universe of human proteins at neXtProt for APMAP: NX_Q9HDC9

Explore proteomics data for APMAP at MOPED

Post-translational modifications:

Ubiquitination² at Lys123, Lys179, Lys220

Glycosylation² at Asn160, Asn196

Modification sites at PhosphoSitePlus

See APMAP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_065392.1

ENSEMBL proteins:

ENSP00000395874 ENSP00000217456 ENSP00000415373

APMAP Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for APMAP OriGene Custom MassSpec OriGene Custom Protein Services for APMAP
	GenScript Custom Purified and Recombinant Proteins Services for APMAP
	Novus Biologicals APMAP Protein Novus Biologicals APMAP Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for APMAP

APMAP Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	OriGene Antibodies for APMAP OriGene Custom Antibody Services for APMAP
	Novus Biologicals APMAP Antibodies
	Search for Antibodies for APMAP at Abcam
	Cloud-Clone Corp. Antibodies for APMAP
	Search ThermoFisher Antibodies for APMAP
	LSBio Antibodies in human, mouse, rat for APMAP

APMAP Assay Products:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for APMAP
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for APMAP
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for APMAP Cloud-Clone Corp. CLIAs for APMAP

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

2 InterPro protein domains:

IPR018119 Strictosidine_synth_cons-reg

IPR011042 6-blade_b-propeller_TolB-like

Graphical View of Domain Structure for InterPro Entry Q9HDC9

ProtoNet protein and cluster: Q9HDC9

1 Blocks protein domain: IPB004141 Strictosidine synthase

UniProtKB/Swiss-Prot: APMAP_HUMAN, Q9HDC9

Similarity: Belongs to the strictosidine synthase family

APMAP for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Molecular Function:

UniProtKB/Swiss-Prot Summary: APMAP_HUMAN, Q9HDC9

Function: Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in

adipocyte differentiation

Gene Ontology (GO): 2 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004064	arylesterase activity	IDA	18513186
GO:0016844	strictosidine synthase activity	IEA	--

APMAP for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for APMAP:

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for APMAP

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for APMAP

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for APMAP

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for APMAP

miRNA Products:		miRTarBase miRNAs that target APMAP: hsa-mir-122-5p (MIRT023339)

		Block miRNA regulation of human, mouse, rat APMAP using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate APMAP
		SwitchGear 3'UTR luciferase reporter plasmid: APMAP 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for APMAP
		Predesigned siRNA for gene silencing in human, mouse, rat APMAP

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for APMAP

Clone Products:		OriGene clones in human, mouse for APMAP (see all 6) OriGene ORF clones in mouse, rat for APMAP OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for APMAP
		Sino Biological Human cDNA Clone for APMAP
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for APMAP
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APMAP

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for APMAP
		Browse ESI BIO Cell Lines and PureStem Progenitors for APMAP

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APMAP

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot

APMAP_HUMAN, Q9HDC9: Membrane; Single-pass type II membrane protein

Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0009986	cell surface	IDA	18513186
GO:0016020	membrane	IDA	18513186
GO:0016021	integral component of membrane	IEA	--

APMAP for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for APMAP
Interactions:

Search GeneGlobe Interaction Network for APMAP

STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

Selected Interacting proteins for APMAP (Q9HDC9^{2, 3} ENSP00000217456⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LOXL3	P58215²^,³, ENSP00000264094⁴	MINT-65567 I2D: score=4 STRING: ENSP00000264094
RASA4	O43374²^,³	MINT-63139 I2D: score=3
DTNB	O60941³	I2D: score=5
ATF2	ENSP00000264110⁴	STRING: ENSP00000264110
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 2 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--
GO:0009058	biosynthetic process	IEA	--

APMAP for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for APMAP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for APMAP gene:

NM_020531.2

Unigene Cluster for APMAP:

Adipocyte plasma membrane associated protein

Hs.472330 [show with all ESTs]

Unigene Representative Sequence: NM_020531

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000451442 ENST00000217456(uc002wty.3 uc002wtz.3 uc010zsw.2)

ENST00000447138

miRNA Products:		Block miRNA regulation of human, mouse, rat APMAP using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate APMAP
		SwitchGear 3'UTR luciferase reporter plasmid: APMAP 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for APMAP
		Predesigned siRNA for gene silencing in human, mouse, rat APMAP

Clone Products:		OriGene clones in human, mouse for APMAP (see all 6) OriGene ORF clones in mouse, rat for APMAP OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for APMAP
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for APMAP
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APMAP

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for APMAP
		Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat APMAP
		QuantiTect SYBR Green Assays in human, mouse, rat APMAP
		QuantiFast Probe-based Assays in human, mouse, rat APMAP

Additional mRNA sequence:

AB033767.1 AK025834.1 AK026866.1 AK291129.1 AK301959.1 AY359076.1 BC003501.1

24 DOTS entries:

DT.100840007 DT.91770648 DT.451611 DT.101969958 DT.100828840 DT.100828833 DT.120832609 DT.91770647

DT.100729059 DT.120832567 DT.100828843 DT.120832515 DT.99991711 DT.100828842 DT.95192602 DT.95192704

DT.95192713 DT.100828839 DT.120832529 DT.120832605 DT.75191588 DT.91666431 DT.120832525 DT.80100506

Selected AceView cDNA sequences (see all 696):

BM664991 AA709451 AA350163 BM561830 BM564471 AA476598 CB069809 NM_020531

AA775837 BM782316 BM510858 CN484721 BQ948912 AA456043 AA552922 AL580093

BE675430 BM708489 BM312119 AA393476 BM763576 Z39456 AA172072 BM738690

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for APMAP (see all 7) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	^	5a	·	5b	^	6	^	7	^	8a	·	8b	^	9a	·	9b	·	9c	^	10a	·	10b
SP1:					-														-				-						-		-
SP2:																			-				-				-		-		-
SP3:																			-				-
SP4:					-				-		-		-		-		-		-				-
SP5:																							-

ECgene alternative splicing isoforms for APMAP

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

APMAP expression in normal human tissues (normalized intensities) APMAP embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

APMAP expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 7) fully expand


Bone (Muscoskeletal System)
Bone Marrow

Brain (Nervous System)
Cerebral Cortex

Thyroid (Endocrine System)

Testis (Reproductive System)

Adipose (Muscoskeletal System)

APMAP Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

APMAP Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.472330

UniProtKB/Swiss-Prot: APMAP_HUMAN, Q9HDC9

Tissue specificity: Liver, glomerular and tubular structures of the kidney, endothelial cells, arterial wall and

pancreatic islets of Langerhans (at protein level). Found ubiquitously in adult as well as in embryonic tissues.

In adult tissue, the highest expression is found in the liver, placenta and heart. Found on the cell surface of

monocytes. In embryonic tissue, the highest expression levels is found in the liver and the kidney

Custom PCR Arrays for APMAP

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for APMAP
		Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat APMAP
		QuantiTect SYBR Green Assays in human, mouse, rat APMAP
		QuantiFast Probe-based Assays in human, mouse, rat APMAP

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APMAP

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of eukaryotes.

Orthologs for APMAP gene from Selected species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Apmap^{1 , 5}	RIKEN cDNA 2310001A20 gene⁵ adipocyte plasma membrane associated protein¹	86.59(n)¹ 89.64(a)¹		2 (74.68 cM)⁵ 71881¹ NM_027977.2¹ NP_082253.1¹ 150583080⁵
chicken (Gallus gallus)	Aves	C3H20ORF3¹	chromosome 3 open reading frame, human C20orf3	71.81(n) 75.66(a)		416715 NM_001006177.1 NP_001006177.1
lizard (Anolis carolinensis)	Reptilia	APMAP⁶	adipocyte plasma membrane associated protein	74(a)	1 ↔ 1	1(254627564-254645527)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.3092²	Transcribed sequence with weak similarity to protein more	76.73(n)		CF591386.1
zebrafish (Danio rerio)	Actinopterygii	Dr.99²	Danio rerio mRNA similar to chromosome 20 open reading more	72.63(n)		BC044505.1
fruit fly (Drosophila melanogaster)	Insecta	Hmu¹	Hemomucin	46.04(n) 37.8(a)		43294 NM_057811.4 NP_477159.1
worm (Caenorhabditis elegans)	Secernentea	CELE_C08E8.2¹	CELE_C08E8.2	47.18(n) 38.02(a)		182407 NM_075189.2 NP_507590.2
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G57030¹	AT3G57030	47.54(n) 40.27(a)		824870 NM_115562.3 NP_191262.2

ENSEMBL Gene Tree for APMAP (if available)
TreeFam Gene Tree for APMAP (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

TryGeneCards Plus

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11479832^1,2	C	--	24943082(+)	`CAAGG-/CCAGCC`	1	--	ds500¹		0	--	--	--	--
rs182703476^1,2		--	24943117(+)	`TACCAC/TAGCTA`	1	--	ds500¹		0	--	--	--	--
rs186321566^1,2		--	24943164(+)	`CTGATG/TTTTTT`	1	--	ds500¹		0	--	--	--	--
rs190975434^1,2	C	--	24943206(+)	`GTGAAC/GTTATT`	1	--	ds500¹		0	--	--	--	--
rs73114342^1,2		--	24943256(+)	`AAATAC/TCCAGG`	1	--	ds500¹		0	--	--	--	--
rs6114963^1,2	H	--	24943295(+)	`TCGTAG/AGCTGG`	1	--	ds500¹		4		NS EA	418
rs149845520^1,2	C	--	24943333(+)	`TTACGC/GCAGAG`	1	--	ds500¹		0	--	--	--	--
rs6114964^1,2	H	--	24943368(+)	`TCTAAG/AGTCGC`	1	--	ds500¹		4		NS EA	420
rs116351737^1,2	C,F	--	24943381(+)	`GCTCCT/CTGCCT`	1	--	ds500¹		1		WA	118
rs113649395^1,2	C,F	--	24943436(+)	`TAGTCG/AGATGG`	1	--	ds500¹		1		CSA	2

HapMap Linkage Disequilibrium report for APMAP (24943561 - 24973615 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for APMAP: --

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing APMAP

DNA2.0 Custom Variant and Variant Library Synthesis for APMAP

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus

5 diseases for APMAP: About MalaCards

polycystic ovary syndrome colorectal cancer endotheliitis pancreatitis

malaria

APMAP for disorders About GeneDecksing

Export disorders for APMAP gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

TryGeneCards Plus

PubMed articles for APMAP gene, integrated from 10 sources (see all 27):
(articles sorted by number of sources associating them with APMAP)

Utopia: connect your pdf to the dynamic
world of online information

Genomic construct and mapping of the gene for CMAP (leukocystatin/cystatin F, CST7) and identification of a proximal novel gene, BSCv (C20orf3). (PubMed id 10945474)^{1, 2, 3, 9} Morita M.... Nishimura S. (Genomics 2000)
Identification of a novel integral plasma membrane protein induced during adipocyte differentiation. (PubMed id 11583587)^{1, 3, 9} Albrektsen T....Fleckner J. (Biochem. J. 2001)
Reconstruction of gene association network reveals a transmembrane protein required for adipogenesis and targeted by PPARI^. (PubMed id 20552250)^{1, 3} Bogner-Strauss J.G....Trajanoski Z. (Cell. Mol. Life Sci. 2010)
Localization and characterization of the novel protein encoded by C20orf3. (PubMed id 18513186)^{1, 2} Ilhan A.... Wagner L. (Biochem. J. 2008)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{1, 2} Liu T.... Smith R.D. (J. Proteome Res. 2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)^{1, 2} Zhang H.... Aebersold R. (Nat. Biotechnol. 2003)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (Genome Res. 2003)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (Nature 2001)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

TryGeneCards Plus

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

TryGeneCards Plus

Entrez Gene: 57136	HGNC: 13238	AceView: C20orf3	Ensembl:ENSG00000101474	euGenes: HUgn57136
ECgene: APMAP	H-InvDB: APMAP

(According to HUGE)
About This Section

TryGeneCards Plus

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
About This Section

TryGeneCards Plus

Name	Description
PharmGKB entry for APMAP	Pharmacogenomics, SNPs, Pathways

Intellectual Property for APMAP gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

TryGeneCards Plus

Patent Information for APMAP gene:
Search GeneIP for patents involving APMAP

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

TryGeneCards Plus


	EMD Millipore genomic analysis products

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Enzyme Activity Assays/Reagents
	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	OriGene Antibodies for APMAP		OriGene RNAi products in human, mouse, rat for APMAP
	Browse OriGene qPCR primer pairs and template standards		OriGene Protein Over-expression Lysate for APMAP
	OriGene Custom Mass Spec		OriGene clones in human, mouse for APMAP
	OriGene qSTAR qPCR primer pairs in human, mouse for APMAP		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for APMAP		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for APMAP		OriGene Custom Protein Services for APMAP

	Block miRNA regulation of human, mouse, rat APMAP using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing APMAP
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat APMAP		Predesigned siRNA for gene silencing in human, mouse, rat APMAP
	QuantiFast Probe-based Assays in human, mouse, rat APMAP		QuantiTect SYBR Green Assays in human, mouse, rat APMAP
	Custom PCR Arrays for APMAP		Search Chromatin IP Primers for APMAP
	Search Pre-validated RT² qPCR Primer Assays in human, mouse, rat APMAP		Search GeneGlobe Interaction Network for APMAP
	Search Regulatory tfbs for APMAP

	GenScript Custom Purified and Recombinant Proteins Services for APMAP		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for APMAP
	GenScript Custom Assay Services for APMAP		GenScript Custom overexpressing Cell Line Services for APMAP
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

Search for Antibodies & Assays

Search Tocris compounds for APMAP

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
	cDNA Clones for APMAP
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	APMAP antibodies
	APMAP proteins
	APMAP lysates

	Search for Antibodies for APMAP at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for APMAP
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for APMAP
	Antibodies for APMAP
	ELISAs for APMAP
	CLIAs for APMAP

Browse ESI BIO Cell Lines and PureStem Progenitors for APMAP

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APMAP

	SwitchGear 3'UTR luciferase reporter plasmids for APMAP
	SwitchGear Promoter luciferase reporter plasmids for APMAP

Search ThermoFisher Antibodies for APMAP

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APMAP

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for APMAP
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for APMAP

LSBio Antibodies in human, mouse, rat for APMAP

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

Browse compounds at ApexBio

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

View Random Gene

Category			(GIFtS: )
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes APMAP gene at Home site.

Version: 3.12.136 22 July 2014
hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4

GeneCards Plus

Advanced Search

Export list of displayed genes

APMAP Gene

Adipocyte Plasma Membrane Associated Protein

Aliases
for APMAP gene

Summaries
for APMAP gene

Genomic Views
for APMAP gene

Proteins
for APMAP gene

APMAP Human Recombinant Protein Products:

APMAP Antibody Products:

APMAP Assay Products:

Domains /
Families
for APMAP gene

Function
for APMAP gene

Localization
for APMAP gene

Pathways & Interactions
for APMAP gene

Drugs & Compounds
for APMAP gene

Transcripts
for APMAP gene

Expression
for APMAP gene

Orthologs
for APMAP gene

Paralogs
for APMAP gene

Genomic Variants
for APMAP gene

Disorders / Diseases
for APMAP gene

Publications
for APMAP gene

External Searches for APMAP gene

Genome Databases showing APMAP gene

Other Databases showing APMAP gene

Specialized Databases showing APMAP gene

Intellectual Property
for APMAP gene

Products
for APMAP gene

View Random Gene

GeneCards Plus

Advanced Search

Export list of displayed genes

APMAP Gene

Adipocyte Plasma Membrane Associated Protein

Aliasesfor APMAP gene

Summariesfor APMAP gene

Genomic Viewsfor APMAP gene

Proteinsfor APMAP gene

APMAP Human Recombinant Protein Products:

APMAP Antibody Products:

APMAP Assay Products:

Domains /Familiesfor APMAP gene

Functionfor APMAP gene

Localizationfor APMAP gene

Pathways & Interactionsfor APMAP gene

Drugs & Compoundsfor APMAP gene

Transcriptsfor APMAP gene

Expression for APMAP gene

Orthologsfor APMAP gene

Paralogsfor APMAP gene

Genomic Variantsfor APMAP gene

Disorders / Diseasesfor APMAP gene

Publicationsfor APMAP gene

External Searches for APMAP gene

Genome Databases showing APMAP gene

Other Databases showing APMAP gene

Specialized Databases showing APMAP gene

Intellectual Propertyfor APMAP gene

Productsfor APMAP gene

View Random Gene

Aliases
for APMAP gene

Summaries
for APMAP gene

Genomic Views
for APMAP gene

Proteins
for APMAP gene

Domains /
Families
for APMAP gene

Function
for APMAP gene

Localization
for APMAP gene

Pathways & Interactions
for APMAP gene

Drugs & Compounds
for APMAP gene

Transcripts
for APMAP gene

Expression
for APMAP gene

Orthologs
for APMAP gene

Paralogs
for APMAP gene

Genomic Variants
for APMAP gene

Disorders / Diseases
for APMAP gene

Publications
for APMAP gene

Intellectual Property
for APMAP gene

Products
for APMAP gene