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Aliases for APITD1-CORT Gene

Aliases for APITD1-CORT Gene

  • APITD1-CORT Readthrough 2 3

External Ids for APITD1-CORT Gene

Summaries for APITD1-CORT Gene

Entrez Gene Summary for APITD1-CORT Gene

  • This locus represents naturally occurring read-through transcription between the neighboring APITD1 (apoptosis-inducing, TAF9-like domain 1) and CORT (cortistatin) genes. Alternative splicing results in multiple transcript variants, two of which encode fusion proteins that share sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2011]

GeneCards Summary for APITD1-CORT Gene

APITD1-CORT (APITD1-CORT Readthrough) is a Protein Coding gene. An important paralog of this gene is APITD1-CORT.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for APITD1-CORT Gene

Genomics for APITD1-CORT Gene

Genomic Location for APITD1-CORT Gene

Start:
10,430,102 bp from pter
End:
10,452,153 bp from pter
Size:
22,052 bases
Orientation:
Plus strand

Genomic View for APITD1-CORT Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for APITD1-CORT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for APITD1-CORT Gene

No data available for Regulatory Elements for APITD1-CORT Gene

Proteins for APITD1-CORT Gene

  • Protein details for APITD1-CORT Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WT10-A0A087WT10
    Recommended name:
    Protein APITD1-CORT
    Protein Accession:
    A0A087WT10
    Secondary Accessions:

    Protein attributes for APITD1-CORT Gene

    Size:
    143 amino acids
    Molecular mass:
    16498 Da
    Quaternary structure:
    No Data Available
  • Protein details for APITD1-CORT Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    R4GMN7-R4GMN7
    Recommended name:
    Protein APITD1-CORT
    Protein Accession:
    R4GMN7
    Secondary Accessions:

    Protein attributes for APITD1-CORT Gene

    Size:
    77 amino acids
    Molecular mass:
    8784 Da
    Quaternary structure:
    No Data Available

neXtProt entry for APITD1-CORT Gene

Proteomics data for APITD1-CORT Gene at MOPED

Post-translational modifications for APITD1-CORT Gene

No Post-translational modifications

Other Protein References for APITD1-CORT Gene

No data available for DME Specific Peptides for APITD1-CORT Gene

Domains for APITD1-CORT Gene

Protein Domains for APITD1-CORT Gene

genes like me logo Genes that share domains with APITD1-CORT: view

No data available for Gene Families and UniProtKB/Swiss-Prot for APITD1-CORT Gene

Function for APITD1-CORT Gene

Gene Ontology (GO) - Molecular Function for APITD1-CORT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0003682 chromatin binding --
GO:0003690 double-stranded DNA binding --
GO:0005179 hormone activity --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with APITD1-CORT: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for APITD1-CORT Gene

Localization for APITD1-CORT Gene

Gene Ontology (GO) - Cellular Components for APITD1-CORT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000776 kinetochore --
GO:0005576 extracellular region --
GO:0005829 cytosol --
GO:0043240 Fanconi anaemia nuclear complex --
GO:0071821 FANCM-MHF complex --
genes like me logo Genes that share ontologies with APITD1-CORT: view

Pathways for APITD1-CORT Gene

SuperPathways for APITD1-CORT Gene

No Data Available

Interacting Proteins for APITD1-CORT Gene

Gene Ontology (GO) - Biological Process for APITD1-CORT Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000278 mitotic cell cycle --
GO:0000712 resolution of meiotic recombination intermediates --
GO:0006281 DNA repair --
GO:0006352 DNA-templated transcription, initiation --
GO:0006974 cellular response to DNA damage stimulus --
genes like me logo Genes that share ontologies with APITD1-CORT: view

No data available for Pathways by source for APITD1-CORT Gene

Transcripts for APITD1-CORT Gene

mRNA/cDNA for APITD1-CORT Gene

(4) REFSEQ mRNAs :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for APITD1-CORT Gene

No ASD Table

Relevant External Links for APITD1-CORT Gene

GeneLoc Exon Structure for
APITD1-CORT
ECgene alternative splicing isoforms for
APITD1-CORT

Expression for APITD1-CORT Gene

mRNA expression in normal human tissues for APITD1-CORT Gene

genes like me logo Genes that share expressions with APITD1-CORT: view

Orthologs for APITD1-CORT Gene

This gene was present in the common ancestor of chordates.

Orthologs for APITD1-CORT Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia APITD1 36
  • 99.52 (n)
  • 98.55 (a)
APITD1 37
  • 69 (a)
OneToMany
cow
(Bos Taurus)
Mammalia APITD1 36
  • 88.11 (n)
  • 83.72 (a)
APITD1 37
  • 61 (a)
OneToMany
dog
(Canis familiaris)
Mammalia APITD1 36
  • 86.5 (n)
  • 80.17 (a)
mouse
(Mus musculus)
Mammalia Apitd1 36
  • 81.2 (n)
  • 77.78 (a)
Apitd1 37
  • 54 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 53 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Apitd1 36
  • 81.94 (n)
  • 76.67 (a)
chicken
(Gallus gallus)
Aves APITD1 36
  • 66.67 (n)
  • 66.67 (a)
APITD1 37
  • 49 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia apitd1 36
  • 66.38 (n)
  • 69.23 (a)
zebrafish
(Danio rerio)
Actinopterygii apitd1 36
  • 63.31 (n)
  • 58.82 (a)
apitd1 37
  • 46 (a)
OneToMany
Species with no ortholog for APITD1-CORT:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for APITD1-CORT Gene

ENSEMBL:
Gene Tree for APITD1-CORT (if available)
TreeFam:
Gene Tree for APITD1-CORT (if available)

Paralogs for APITD1-CORT Gene

Paralogs for APITD1-CORT Gene

Selected SIMAP similar genes for APITD1-CORT Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with APITD1-CORT: view

Variants for APITD1-CORT Gene

Sequence variations from dbSNP and Humsavar for APITD1-CORT Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1307487 -- 10,446,610(+) agact(A/G)taggt intron-variant
rs1307488 -- 10,447,053(+) AAACA(A/G)TCATT intron-variant
rs1307489 -- 10,447,179(+) GCTGC(A/G)ACACC intron-variant
rs2847340 -- 10,445,753(+) tgcag(G/T)ggcac intron-variant
rs4285702 -- 10,446,461(+) gcacc(C/T)ggcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for APITD1-CORT Gene

Variant ID Type Subtype PubMed ID
dgv17e1 CNV Complex 17122850
essv3548 CNV CNV 17122850

Relevant External Links for APITD1-CORT Gene

HapMap Linkage Disequilibrium report
APITD1-CORT

Disorders for APITD1-CORT Gene

No disorders were found for APITD1-CORT Gene.

No data available for UniProtKB/Swiss-Prot for APITD1-CORT Gene

Publications for APITD1-CORT Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  3. A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours. (PMID: 15328517) Krona C. … Martinsson T. (Br. J. Cancer 2004) 3
  4. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3

Products for APITD1-CORT Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate APITD1-CORT
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for APITD1-CORT
  • Block miRNA regulation of APITD1-CORT using miScript Target Protectors

Sources for APITD1-CORT Gene

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