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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APITD1 Gene

protein-coding   GIFtS: 47
GCID: GC01P010492

Apoptosis-Inducing, TAF9-Like Domain 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Apoptosis-Inducing, TAF9-Like Domain 11 2     FAAP162 3
Centromere Protein S1 2     MHF12 3
Apoptosis-Inducing TAF9-Like Domain-Containing Protein 12 3     FANCM-Interacting Histone Fold Protein 12 3
CENP-S2 3     Fanconi Anemia-Associated Polypeptide Of 16 KDa2 3
CENPS2 3     

External Ids:    HGNC: 231631   Entrez Gene: 3787082   Ensembl: ENSG000001752797   OMIM: 6091305   UniProtKB: Q8N2Z93   

Export aliases for APITD1 gene to outside databases

Previous GC identifers: GC00U913093 GC01U901121 GC01P010412 GC01P009643


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for APITD1 Gene:
This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a
TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is
required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma
tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell
death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex,
the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement
with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore.
Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through
transcripts also exist between this gene and the downstream cortistatin (CORT) gene, as represented in
GeneID:100526739. An APITD1-related pseudogene has been identified on chromosome 7. (provided by RefSeq, Nov
2010)

GeneCards Summary for APITD1 Gene: 
APITD1 (apoptosis-inducing, TAF9-like domain 1) is a protein-coding gene. Diseases associated with APITD1 include gastric antral vascular ectasia, and systemic scleroderma, and among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include double-stranded DNA binding and protein heterodimerization activity. An important paralog of this gene is APITD1-CORT.

UniProtKB/Swiss-Prot: CENPS_HUMAN, Q8N2Z9
Function: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance.
Required for optimal chromatin association of the FA core complex. Required for efficient damage-induced
monoubiquitination and focus formation of FANCD2. Stabilizes FAAD24, FANCM and STRA13/CENPX in the FA core
complex. Plays a role in DNA interstrand cross-linking (ICL) repair and in recovery of replication forks stalled
by topoisomerase I-DNA cleavage intermediates induced by camptothecin. Component of the heterotetrameric
CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly.
Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays
an important role in mitotic progression and chromosome segregation. Component of the CENPA-CAD (nucleosome
distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins,
mitotic progression and chromosome segregation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APITD1 gene promoter:
         GR   GR-beta   STAT3   GR-alpha   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): APITD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for APITD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APITD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.22   Ensembl cytogenetic band:  1p36.22   HGNC cytogenetic band: 1p36.22

APITD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APITD1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P010492:  view genomic region     (about GC identifiers)

Start:
10,490,159 bp from pter      End:
10,512,210 bp from pter
Size:
22,052 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CENPS_HUMAN, Q8N2Z9 (See protein sequence)
Recommended Name: Centromere protein S  
Size: 138 amino acids; 15893 Da
Subunit: Component of a discrete APITD1/CENPS complex composed of at least APITD1/CENPS and STRA13/CENPX. Belongs
to the multisubunit FA complex composed of APITD1/CENPS, FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9,
FANCM, FAAP24 and STRA13/CENPX. Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO,
CENPP, CENPQ, CENPR and APITD1/CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least
composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU. Interacts with APITD1/CENPS, FANCM and
FAAP24. Binds DNA. Component of a heterotetrameric CENP-T-W-S-X complex composed of APITD1/CENPS, STRA13/CENPX,
CENPT and CENPW
Subcellular location: Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively
localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. The CENPA-CAD complex is
probably recruited on centromeres by the CENPA-NAC complex
4 PDB 3D structures from and Proteopedia for APITD1:
4DRA (3D)        4DRB (3D)        4E44 (3D)        4E45 (3D)    
Secondary accessions: Q8NFE5 Q8NFG5
Alternative splicing: 3 isoforms:  Q8N2Z9-1   Q8N2Z9-2   Q8N2Z9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for APITD1: NX_Q8N2Z9

Explore proteomics data for APITD1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N2Z9

  • APITD1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    APITD1 Protein Expression
    REFSEQ proteins: NP_954988.1  
    ENSEMBL proteins: 
     ENSP00000308583   ENSP00000468629   ENSP00000473509   ENSP00000473401  
    Reactome Protein details: Q8N2Z9
    Human Recombinant Protein Products for APITD1: 
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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005576extracellular region ----
    GO:0005829cytosol TAS--
    GO:0043240Fanconi anaemia nuclear complex IDA--
    GO:0071821FANCM-MHF complex IDA--

    APITD1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR003162 TFIID-31
     IPR009072 Histone-fold

    Graphical View of Domain Structure for InterPro Entry Q8N2Z9

    ProtoNet protein and cluster: Q8N2Z9

    UniProtKB/Swiss-Prot: CENPS_HUMAN, Q8N2Z9
    Similarity: Belongs to the TAF9 family


    APITD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CENPS_HUMAN, Q8N2Z9
    Function: DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance.
    Required for optimal chromatin association of the FA core complex. Required for efficient damage-induced
    monoubiquitination and focus formation of FANCD2. Stabilizes FAAD24, FANCM and STRA13/CENPX in the FA core
    complex. Plays a role in DNA interstrand cross-linking (ICL) repair and in recovery of replication forks stalled
    by topoisomerase I-DNA cleavage intermediates induced by camptothecin. Component of the heterotetrameric
    CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly.
    Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays
    an important role in mitotic progression and chromosome segregation. Component of the CENPA-CAD (nucleosome
    distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins,
    mitotic progression and chromosome segregation

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA--
    GO:0003682chromatin binding IDA--
    GO:0003690contributes to double-stranded DNA binding IDA--
    GO:0005179hormone activity ----
    GO:0005515protein binding IPI--
         
    APITD1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for APITD1 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for APITD1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    4Fanconi anemia pathway
    Fanconi anemia pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/9        Reactome Pathways for APITD1 (see all 9)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Cell Cycle


    1         Kegg Pathway  (Kegg details for APITD1):
        Fanconi anemia pathway


    APITD1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APITD1

    5/13 Interacting proteins for APITD1 (Q8N2Z91, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STRA13A8MT691, 2, 3EBI-5529649,EBI-5529694 MINT-8434649 MINT-8434669 MINT-8434686 MINT-8434303 I2D: score=1 
    FANCMQ8IYD82, 3MINT-8434669 MINT-8434303 I2D: score=1 
    BLMP541323I2D: score=1 
    C17orf70Q0VG063I2D: score=1 
    C19orf40Q9BTP73I2D: score=1 
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0000712resolution of meiotic recombination intermediates IMP--
    GO:0006281DNA repair IDA--
    GO:0006352DNA-dependent transcription, initiation ----
    GO:0006974response to DNA damage stimulus IMP--

    APITD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APITD1 (CENPS)

    Search CenterWatch for drugs/clinical trials and news about APITD1 / CENPS

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for APITD1 gene: 
    NM_199294.2  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000309048(uc001are.3) ENST00000602486 ENST00000477755(uc021oge.1)
    ENST00000462462 ENST00000464507 ENST00000602787 ENST00000602296
    miRNA
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    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APITD1 expression in normal human tissues (normalized intensities)      APITD1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    APITD1 Expression
    About this image


    APITD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/10 selected tissues (see all 10) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 11 entries
             Zeugopod Long Bone
             skeleton/pectoral girdle and thoracic body wall/scapula   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 7 entries
             Meckel's Cartilage
             sensory organ/nose/nasal septum   
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 4 entries
             skeleton/cranium/chondrocranium   
     
     Nose (Sensory Organs)
             sensory organ/nose/nasal septum   
     
     Mesoderm (Gastrulation Derivatives)
             skeleton/axial skeleton   

    See APITD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APITD1

    UniProtKB/Swiss-Prot: CENPS_HUMAN, Q8N2Z9
    Tissue specificity: Ubiquitously expressed

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for APITD1 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Apitd11 , 5 apoptosis-inducing, TAF9-like domain 11, 5 81.33(n)1
    76.8(a)1
      4 (78.89 cM)5
    699281  NM_027263.21  NP_081539.11 
     1491271215 
    chicken
    (Gallus gallus)
    Aves APITD11 apoptosis-inducing, TAF9-like domain 1 66.67(n)
    66.67(a)
      771417  NM_001204932.1  NP_001191861.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1943191 zgc:194319 63.84(n)
    59.32(a)
      569270  NM_001128749.1  NP_001122221.1 


    ENSEMBL Gene Tree for APITD1 (if available)
    TreeFam Gene Tree for APITD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for APITD1 gene
    APITD1-CORT2  
    1 SIMAP similar gene for APITD1 using alignment to 2 protein entries:     CENPS_HUMAN (see all proteins):
    APITD1-CORT

    APITD1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for APITD1
    PGOHUM00000233133


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for APITD1:    About this table     
    Variant IDTypeSubtypePubMed ID
    essv3548CNV CNV17122850
    dgv17e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609130    OMIM disorders: --

    8 diseases for APITD1:    About MalaCards
    gastric antral vascular ectasia    systemic scleroderma    anemia    neuroblastoma
    fanconi's anemia    calcinosis    scleroderma    melanoma

    2 diseases from the University of Copenhagen DISEASES database for APITD1:
    Systemic scleroderma     Gastric antral vascular ectasia

    APITD1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): APITD1
    Human Genome Epidemiology (HuGE) Navigator: APITD1 (3 documents)

    Export disorders for APITD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APITD1 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with APITD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours. (PubMed id 15328517)1, 2, 3, 9 Krona C....Martinsson T. (2004)
    2. The human CENP-A centromeric nucleosome-associated complex. (PubMed id 16622419)1, 2, 3 Foltz D.R....Cleveland D.W. (2006)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. The CENP-S complex is essential for the stable assembly of outer kinetochore structure. (PubMed id 19620631)1, 2 Amano M....Fukagawa T. (2009)
    5. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. (PubMed id 16622420)1, 3 Okada M....Fukagawa T. (2006)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    7. The structure of the FANCM-MHF complex reveals physica l features for functional assembly. (PubMed id 22510687)1 Tao Y....Teng M. (2012)
    8. A ubiquitin-binding protein, FAAP20, links RNF8-mediat ed ubiquitination to the Fanconi anemia DNA repair network. (PubMed id 22705371)1 Yan Z....Wang W. (2012)
    9. CENP-T-W-S-X forms a unique centromeric chromatin structure with a histone-like fold. (PubMed id 22304917)2 Nishino T.... Fukagawa T. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 378708 HGNC: 23163 Ensembl:ENSG00000175279 euGenes: HUgn378708 ECgene: APITD1 Kegg: 378708
    H-InvDB: APITD1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APITD1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for APITD1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for APITD1 gene:
    Search GeneIP for patents involving APITD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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