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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APBB3 Gene

protein-coding   GIFtS: 56
GCID: GC05M139937

Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member...

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 31 2     Amyloid Beta A4 Precursor Protein-Binding Family B Member 32
FE65L22 3 5     Amyloid Precursor Interacting Protein2
Protein Fe65-Like 22 3     FE65-Like Protein 22
SRA2     Fe65L23

External Ids:    HGNC: 207081   Entrez Gene: 103072   Ensembl: ENSG000001131087   OMIM: 6027115   UniProtKB: O957043   

Export aliases for APBB3 gene to outside databases

Previous GC identifers: GC05M140520 GC05M139913 GC05M139959 GC05M139960 GC05M139910 GC05M139918 GC05M135084


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for APBB3 Gene:
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to
the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other
APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP.
Multiple transcript variants encoding several different isoforms have been found for this gene. (provided by
RefSeq, Jul 2008)

GeneCards Summary for APBB3 Gene: 
APBB3 (amyloid beta (A4) precursor protein-binding, family B, member 3) is a protein-coding gene. Diseases associated with APBB3 include alzheimer's disease, and obesity. An important paralog of this gene is APBB2.

UniProtKB/Swiss-Prot: APBB3_HUMAN, O95704
Function: May modulate the internalization of beta-amyloid precursor protein

Gene Wiki entry for APBB3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_029289.11  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APBB3 gene promoter:
         CREB   TBP   p53   NRSF form 1   deltaCREB   TFIID   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAPBB3 promoter sequence
   Search SABiosciences Chromatin IP Primers for APBB3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APBB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31   Ensembl cytogenetic band:  5q31.3   HGNC cytogenetic band: 5q31

APBB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APBB3 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M139937:  view genomic region     (about GC identifiers)

Start:
139,937,853 bp from pter      End:
139,973,337 bp from pter
Size:
35,485 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: APBB3_HUMAN, O95704 (See protein sequence)
Recommended Name: Amyloid beta A4 precursor protein-binding family B member 3  
Size: 486 amino acids; 52585 Da
Subunit: Binds to the intracellular domain of the beta-amyloid precursor protein. Also binds to APP-like proteins
2 PDB 3D structures from and Proteopedia for APBB3:
2DYQ (3D)        2YSC (3D)    
Secondary accessions: B3KQN9 Q08AG4 Q9NYX6 Q9NYX7 Q9NYX8
Alternative splicing: 4 isoforms:  O95704-1   O95704-2   O95704-3   O95704-4   

Explore the universe of human proteins at neXtProt for APBB3: NX_O95704

Explore proteomics data for APBB3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O95704

  • APBB3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    APBB3 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_006042.3  NP_573418.2  NP_573419.2  NP_573420.2  

    ENSEMBL proteins: 
     ENSP00000426107   ENSP00000422718   ENSP00000349177   ENSP00000346378   ENSP00000350171  
     ENSP00000427272   ENSP00000402591   ENSP00000424317   ENSP00000444013   ENSP00000351389  

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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for APBB3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0015629actin cytoskeleton IDA--

    APBB3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR006020 PTyr_interaction_dom
     IPR001202 WW_dom
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry O95704

    ProtoNet protein and cluster: O95704

    1 Blocks protein domain: IPB006020 Phosphotyrosine interaction domain

    UniProtKB/Swiss-Prot: APBB3_HUMAN, O95704
    Similarity: Contains 2 PID domains
    Similarity: Contains 1 WW domain


    APBB3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: APBB3_HUMAN, O95704
    Function: May modulate the internalization of beta-amyloid precursor protein

         Genatlas biochemistry entry for APBB3:
    amyloid beta (A4) precursor protein binding B3,murine homolog,FE65 like gene,interacting with Alzheimer's beta
    amyloid precursor protein

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10081969
         
    APBB3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for APBB3:
     Decreased TP53 protein express  Increased cell death HMECs cel 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APBB3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for APBB3 (O957042, 3 ENSP000003463784) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERBB2P046262, 3MINT-74477 I2D: score=2 
    EGFRP005332, 3, ENSP000002754934MINT-74475 MINT-74476 I2D: score=2 STRING: ENSP00000275493
    APPP050673, ENSP000002849814I2D: score=7 STRING: ENSP00000284981
    APLP1P516933, ENSP000002218914I2D: score=1 STRING: ENSP00000221891
    APLP2Q064813, ENSP000002635744I2D: score=5 STRING: ENSP00000263574
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035556intracellular signal transduction ----

    APBB3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APBB3

    Search CenterWatch for drugs/clinical trials and news about APBB3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for APBB3 gene (6 alternative transcripts): 
    NM_006051.3  NM_133172.2  NM_133173.2  NM_133174.2  NM_133175.1  NM_133176.1  

    Unigene Cluster for APBB3:

    Amyloid beta (A4) precursor protein-binding, family B, member 3
    Hs.529449  [show with all ESTs]
    Unigene Representative Sequence: AK125244
    18/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25):
    ENST00000515056(uc003lgb.1) ENST00000509914 ENST00000510241(uc003lgc.1 uc003lgd.1 uc010jfp.1 uc011czi.1 uc021yeg.1 uc003lgf.1)
    ENST00000467078 ENST00000356738 ENST00000354402 ENST00000357560(uc003lge.1 uc021yeh.1)
    ENST00000511896 ENST00000412920 ENST00000511201 ENST00000504872 ENST00000506289
    ENST00000511463 ENST00000503979 ENST00000513507 ENST00000505617 ENST00000506958
    ENST00000507279

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    hsa-miR-1290 hsa-miR-142-5p hsa-miR-98 hsa-let-7d hsa-miR-202 hsa-let-7c hsa-miR-340 hsa-let-7i
    SwitchGear 3'UTR luciferase reporter plasmidAPBB3 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AB018247.1 AB079687.1 AB094990.1 AB209839.1 AF224708.1 AF224709.1 AF224710.1 AF224711.1 
    AK074885.1 AK075280.1 AK125244.1 AK304824.1 AK307170.1 BC013158.1 BC125187.1 

    23 DOTS entries:

    DT.120809089  DT.95166855  DT.95204941  DT.92437826  DT.97769432  DT.92458990  DT.97855095  DT.100815438 
    DT.86840740  DT.100815437  DT.100810894  DT.40316838  DT.100815427  DT.120809268  DT.99971860  DT.120809171 
    DT.120809267  DT.120809095  DT.120809104  DT.92458996  DT.95167015  DT.92027807  DT.97798844 

    24/420 AceView cDNA sequences (see all 420):

    AI207238 BQ575210 AW291759 CR595828 BU687231 BE513494 NM_133174 BM980607 
    AA833851 BU675705 W49526 AA804604 BM473616 BE793975 AA384327 BM680258 
    NM_133176 CB853471 BM717898 AI524742 CA433678 BQ052761 CB139835 BG315276 

    GeneLoc Exon Structure

    5/20 Alternative Splicing Database (ASD) splice patterns (SP) for APBB3 (see all 20)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c · 11d ^ 12a ·
    SP1:                                                              -     -                                   -                       -     -                     
    SP2:                                                              -     -                                         -                 -     -                     
    SP3:                                                              -     -                                         -     -     -     -                           
    SP4:                                                              -     -                                         -     -     -     -     -                     
    SP5:                                                              -     -                                                                                       

    ExUns: 12b ^ 13a · 13b · 13c ^ 14 ^ 15a · 15b · 15c · 15d · 15e ^ 16a · 16b ^ 17a · 17b · 17c ^ 18 ^ 19a · 19b ^ 20 ^ 21a · 21b · 21c
    SP1:                    -           -                       -                                                                           
    SP2:                    -           -                       -                                                                           
    SP3:                    -           -                       -                                                                           
    SP4:                    -           -                       -                                                                           
    SP5:                    -           -                       -                                                                           


    ECgene alternative splicing isoforms for APBB3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APBB3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTAACTCTG
    APBB3 Expression
    About this image


    See APBB3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APBB3

    SOURCE GeneReport for Unigene cluster: Hs.529449

    UniProtKB/Swiss-Prot: APBB3_HUMAN, O95704
    Tissue specificity: Expressed in various tissues

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for APBB3 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Apbb31 , 5 amyloid beta (A4) precursor protein-binding, family more1, 5 88.04(n)1
    91.75(a)1
      18 (19.46 cM)5
    2253721  NM_146085.11  NP_666197.11 
     366711605 
    chicken
    (Gallus gallus)
    Aves APBB31 amyloid beta (A4) precursor protein-binding, family more 66.05(n)
    59.26(a)
      427608  XM_425180.3  XP_425180.3 
    lizard
    (Anolis carolinensis)
    Reptilia APBB36
    APBB16
    (see all 3)
    Uncharacterized protein
    (see all 3)
    55(a)
    33(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    4(77903757-77913860)
    GL344762.1(3854-6181)
    zebrafish
    (Danio rerio)
    Actinopterygii APBB36
    amyloid beta (A4) precursor protein-binding, famil...
    51(a)
    1 ↔ 1
    21(39379602-39430884)
    worm
    (Caenorhabditis elegans)
    Secernentea feh-16
    Protein FEH-1, isoform b
    17(a)
    1 → many
    III(2549927-2560686)


    ENSEMBL Gene Tree for APBB3 (if available)
    TreeFam Gene Tree for APBB3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for APBB3 gene
    APBB22  APBB12  
    5 SIMAP similar genes for APBB3 using alignment to 8 protein entries:     APBB3_HUMAN (see all proteins):
    Fe65L2 isoform 484    Fe65L2    APBB2    APBB1    DKFZp686G05200

    APBB3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/134 SNPs in APBB3 are shown (see all 134)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs787059381,2
    C,F--139939874(+) CCACCA/CACCCA 4 -- int13Minor allele frequency- C:0.02CSA WA EU 1444
    rs1824827201,2
    C--139939887(+) CCCACC/TCATGA 4 -- int10--------
    rs2012389321,2
    --139939921(+) AGCTTC/TAGAGA 8 K E mis10--------
    rs1480099891,2
    C,F--139939929(+) AGAGTC/TCCCCT 8 E G mis12Minor allele frequency- T:0.00NA EU 5869
    rs617369401,2
    C,F--139939961(+) GCTGCG/ACACTG 8 /C syn14Minor allele frequency- A:0.02NS NA EU 6067
    rs2007970981,2
    --139940030(+) CCAATA/GAATGT 8 F syn10--------
    rs1156112311,2
    C,F--139940044(+) AAGGCG/ACACAG 8 /R /C mis12Minor allele frequency- A:0.00NA 4644
    rs1995454271,2
    --139940061(+) GCCACA/GATGGC 8 S L mis10--------
    rs1424982791,2
    C--139940128(+) AGCACA/GGGCCA 4 -- int10--------
    rs2018500621,2
    C--139940129(+) GCACGA/GGCCAG 4 -- int10--------

    HapMap Linkage Disequilibrium report for APBB3 (139937853 - 139973337 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for APBB3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv462462CNV Loss19166990


    Human Gene Mutation Database (HGMD): APBB3
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing APBB3
    DNA2.0 Custom Variant and Variant Library Synthesis for APBB3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602711    OMIM disorders: --

    2 diseases for APBB3:    About MalaCards
    alzheimer's disease    obesity


    APBB3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): APBB3

    Export disorders for APBB3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APBB3 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with APBB3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein. (PubMed id 10081969)1, 2 Tanahashi H. (1999)
    4. Genome structure and chromosomal mapping of the gene for Fe65L2 interacting with Alzheimer's beta-amyloid precursor protein. (PubMed id 10329396)1, 2 Tanahashi H. and Tabira T. (1999)
    5. The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. (PubMed id 9407065)1, 3 Ermekova K.S....Sudol M. (1997)
    6. Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains. (PubMed id 12153398)1, 9 Tanahashi H. and Tabira T. (2002)
    7. Extensive proteomic screening identifies the obesity- related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression i n early Alzheimer's disease. (PubMed id 20205790)1 Kajiwara Y....Buxbaum J.D. (2010)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. A quantitative protein interaction network for the ErbB receptors using protein microarrays. (PubMed id 16273093)1 Jones R.B....MacBeath G. (2006)
    10. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10307 HGNC: 20708 AceView: APBB3andSRA1 Ensembl:ENSG00000113108 euGenes: HUgn10307
    ECgene: APBB3 H-InvDB: APBB3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APBB3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for APBB3 gene:
    Search GeneIP for patents involving APBB3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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