Aliases for APBB3 Gene
External Ids for APBB3 Gene
Previous GeneCards Identifiers for APBB3 Gene
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for APBB3 Gene
APBB3 (Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 3) is a Protein Coding gene. Diseases associated with APBB3 include alzheimer disease. GO annotations related to this gene include transcription factor binding and beta-amyloid binding. An important paralog of this gene is APBB2.
UniProtKB/Swiss-Prot for APBB3 Gene
May modulate the internalization of beta-amyloid precursor protein