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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

APBA3 Gene

protein-coding   GIFtS: 54
GCID: GC19M003750

amyloid beta (A4) precursor protein-binding, family A, member...
 Explore 6 diseases affiliated with
APBA3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for APBA3    

Aliases
for APBA3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 31 2     Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 3 (X11-Like 2)2
X11L21 2 3     Amyloid Beta A4 Precursor Protein-Binding Family A Member 32
Mint31     Mint-33
Adapter Protein X11gamma2 3     Phosphotyrosine-Binding/-Interacting Domain (PTB)-Bearing Protein2
Neuron-Specific X11L2 Protein2 3     X11-Like 2 Protein2
Neuronal Munc18-1-Interacting Protein 32 3     MINT33
MGC:158152     Mint-33

External Ids:    HGNC: 5801   Entrez Gene: 95462   Ensembl: ENSG000000111327   OMIM: 6042625   UniProtKB: O960183   

Export aliases for APBA3 gene to outside databases

Previous GC identifers: GC19M003843 GC19M003690 GC19M003701 GC19M003515


Summaries
for APBA3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for APBA3:
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with
the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction
processes. This gene is a candidate gene for Alzheimer's disease. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: APBA3_HUMAN, O96018
Function: May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May
enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN

Gene Wiki entry for APBA3


Genomic Views
for APBA3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011255.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the APBA3 gene promoter:
         Max1   NF-1/L   NF-1   p300   AP-2gamma   PPAR-gamma1   AP-2beta   PPAR-gamma2   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: APBA3 promoter sequence
   Search SABiosciences Chromatin IP Primers for APBA3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APBA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

APBA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
APBA3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M003750:  view genomic region     (about GC identifiers)

Start:
 3,750,771 bp from pter      End:
 3,761,697 bp from pter
Size:
 10,927 bases      Orientation:
 minus strand

Proteins
for APBA3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: APBA3_HUMAN, O96018 (See protein sequence)
Recommended Name: Amyloid beta A4 precursor protein-binding family A member 3  
Size: 575 amino acids; 61454 Da
Subunit: Binds to the cytoplasmic domain of amyloid protein (APP) in vivo. Interacts with HIF1AN (via N-terminus)
Subcellular location: Cytoplasm, perinuclear region
2 PDB 3D structures from and Proteopedia for APBA3:
2YT7 (3D)        2YT8 (3D)    
Secondary accessions: O60483 Q9UPZ2

Explore the universe of human proteins at neXtProt for APBA3: NX_O96018

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O96018

    • APBA3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004877.1  
    ENSEMBL proteins: 
     ENSP00000315136  

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    Uscn Proteins for APBA3

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0016020membrane NAS--
    GO:0048471perinuclear region of cytoplasm IDA19726677


    APBA3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for APBA3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    APBA3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001478 PDZ
     IPR006020 PTyr_interaction_dom
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry O96018

    ProtoNet protein and cluster: O96018

    2 Blocks protein families:
    IPB001478 PDZ/DHR/GLGF domain
    IPB006020 Phosphotyrosine interaction domain


    UniProtKB/Swiss-Prot: APBA3_HUMAN, O96018
    Domain: Composed of an N-terminal domain, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with
    the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach
    proteins to the plasma membrane
    Similarity: Contains 2 PDZ (DHR) domains
    Similarity: Contains 1 PID domain


    Function
    for APBA3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: APBA3_HUMAN, O96018
    Function: May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May
    enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN

         Genatlas biochemistry entry for APBA3:
    amyloid beta (A4) precursor protein binding,family A,member 3 (X11-like 2),expressed in various tissues

    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate APBA3:
    hsa-miR-124 hsa-miR-506 hsa-miR-128 hsa-miR-3681*
    SwitchGear 3'UTR luciferase reporter plasmid: APBA3 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001540beta-amyloid binding IEA--
    GO:0004857enzyme inhibitor activity IDA19726677
    GO:0005515protein binding IPI--
    GO:0019899enzyme binding IPI19726677


    APBA3 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for APBA3: Apba3tm1.1Sud Apba3tm1.2Ski
         6 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Apba3):
     homeostasis/metabolism  immune system  mortality/aging  nervous system  no phenotypic analysis 
     normal 

    APBA3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for APBA3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APBA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for APBA3 (O960181, 2, 3 ENSP000003151364) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BCRP112742, 3, ENSP000003035074MINT-69545 MINT-69538 MINT-69541 MINT-69543 MINT-69544 I2D: score=3 STRING: ENSP00000303507
    TANKQ928441, 3, ENSP000002590754EBI-6115839,EBI-356349 I2D: score=1 STRING: ENSP00000259075
    TBKBP1A7MCY61, 3, ENSP000003547774STRING: ENSP00000354777 EBI-6115839,EBI-359969 I2D: score=1 
    EGFRP005332, 3, ENSP000002754934MINT-74464 I2D: score=2 STRING: ENSP00000275493
    APPP050673, ENSP000002849814I2D: score=4 STRING: ENSP00000284981
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001701in utero embryonic development IEA--
    GO:0007268synaptic transmission IEA--
    GO:0010468regulation of gene expression IEA--
    GO:0015031protein transport IEA--
    GO:0035556intracellular signal transduction NAS--


    APBA3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for APBA3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for APBA3
    Search CenterWatch for drugs/clinical trials and news about APBA3 

    Transcripts
    for APBA3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for APBA3 gene: 
    NM_004886.3  

    Unigene Cluster for APBA3:

    Amyloid beta (A4) precursor protein-binding, family A, member 3
    Hs.465607  [show with all ESTs]
    Unigene Representative Sequence: AB209603
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000588984 ENST00000590064 ENST00000316757(uc002lyo.1 uc002lyp.1)
    ENST00000591678 ENST00000586991 ENST00000592826 ENST00000590238 ENST00000589934


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    hsa-miR-124 hsa-miR-506 hsa-miR-128 hsa-miR-3681*
    SwitchGear 3'UTR luciferase reporter plasmid: APBA3 3' UTR sequence
    Inhib. RNA
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB021638.1 AB209603.1 AF029110.1 BC086306.1 

    8 DOTS entries:

    DT.95273579  DT.87014942  DT.100025307  DT.100025306  DT.100756467  DT.40131720  DT.91914121  DT.95273578 

    24/93 AceView cDNA sequences (see all 93):

    CD674507 BI918185 AA346833 BU069794 BU624296 AB021638 NM_004886 BE549738 
    CR623670 BM009160 CK299463 AW135383 BM553060 BE274973 BX426745 BQ129290 
    AL548770 BU070021 BG488505 CF132397 BM552575 BM904326 BM129693 BQ707748 

    GeneLoc Exon Structure


    Expression
    for APBA3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    APBA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCCCCGGAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See APBA3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for APBA3

    SOURCE GeneReport for Unigene cluster: Hs.465607

    UniProtKB/Swiss-Prot: APBA3_HUMAN, O96018
    Tissue specificity: Expressed in all tissues examined with lower levels in brain and testis

        SABiosciences Expression via Pathway-Focused PCR Array including APBA3: 
              Alzheimer's Disease in human mouse rat

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    In Situ
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    Orthologs
    for APBA3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for APBA3 gene from 7/21 species (see all 21)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Apba31 , 5 amyloid beta (A4) precursor protein-binding, family A, member 3 less1, 5 76.82(n)1
    76.71(a)1    		   10 (39.72 cM)5
    572671  NM_018758.21  NP_061228.11 
     812681725 
    chicken
    (Gallus gallus)    		 Aves APBA31 amyloid beta (A4) precursor protein-binding, family A, member 3 less 67.98(n)
    64.42(a)    		   420069  XM_418188.3  XP_418188.2 
    lizard
    (Anolis carolinensis)    		 Reptilia APBA26
    		 --
    		 63(a)
    		 1 ↔ 1
    		 AAWZ02041380(2101-4518)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.106672 Xenopus laevis transcribed sequence with weak similarity to protein pirA47176 (H.sapiens) A47176 probable transmembrane protein X11 - human (fragment) less 73.92(n)    BJ627951.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii im:71375971 im:7137597 59.97(n)
    59.19(a)    		   449850  XM_003199417.1  XP_003199465.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta X11L6
    X11Lbeta6
    		 X11Lbeta
    		 18(a)
    10(a)
    		 many ↔ many
    many ↔ many
    		 X(17493641-17500912)
    X(10521770-10604900)
    worm
    (Caenorhabditis elegans)    		 Secernentea lin-103 Phosphotyrosine interaction domain
    (PTB/PID)., PDZ domain (Also known as DHR
    or GLGF). (2 domains) less    		 51(a)   I(8118196-8127374)   --


    ENSEMBL Gene Tree for APBA3 (if available)
    TreeFam Gene Tree for APBA3 (if available) 

    Paralogs
    for APBA3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for APBA3 gene
    APBA22  APBA12  
    3 SIMAP similar genes for APBA3 using alignment to 1 protein entry:     APBA3_HUMAN:
    X11L2    APBA1    APBA2

    APBA3 for paralogs           About GeneDecksing



    Genomic Variants
    for APBA3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/322 NCBI SNPs in APBA3 are shown (see all 322)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1399083961,2
    		--3750414(+) TGGGGA/CTTTGA 3 -- ds5001 int10--------
    rs1497936841,2
    		--3750421(+) TTGAGG/TGATGC 3 -- int1 ds50010--------
    rs1457824341,2
    		--3750452(+) CCCTAA/CCCATG 3 -- int1 ds50010--------
    rs1138692941,2
    		F,--3750474(+) GTGCTC/TATCTC 3 -- int1 ds50011Minor allele frequency- T:0.50CSA 4
    rs342785951,2
    		C,F,--3750689(+) CTCTCG/CAAGGC 3 -- ds5001 ut315Minor allele frequency- C:0.04NA EU 407
    rs10462781,2
    		C,F,A,H,--3750690(+) TCTCGC/AAGGCT 3 -- ds5001 ut3130Minor allele frequency- A:0.47MN NS EA NA WA CSA EU 3180
    rs1405065801,2
    		C,--3750704(+) AGCTGC/GTCCGT 3 -- ds5001 ut310--------
    rs1911778181,2
    		--3750817(+) CCGGCC/TTCTAG 3 -- int1 ut310--------
    rs116734421,2
    		H--3750851(+) CTCGGA/TCCCGT 3 -- int1 ut31 ese30--------
    rs48075051,2
    		C,F,A,H,--3750869(+) GATCCG/AAGACT 3 -- int1 ut31 ese322Minor allele frequency- A:0.12NS EA NA WA 2760

    HapMap Linkage Disequilibrium report for APBA3 (3750771 - 3761697 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for APBA3
         1 CNV: 30067

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for APBA3

    Disorders / Diseases
    for APBA3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    APBA3 for disorders           About GeneDecksing

    OMIM gene information: 604262    OMIM disorders: --

    6 diseases for APBA3:    About MalaCards
    alzheimer's disease    melanotic neuroectodermal tumor    neuronitis    rectal neoplasm
    neuroectodermal tumors    hypoxia

    1 disease from the University of Copenhagen DISEASES database for APBA3:
    Melanotic neuroectodermal tumor
    Human Genome Epidemiology (HuGE) Navigator: APBA3 (1 document)

    Export disorders for APBA3 gene to outside databases

    Publications
    for APBA3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for APBA3 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with APBA3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. X11L2, a new member of X11 protein family interacts with Alzheimer's beta-amyloid precursor protein. (PubMed id 10049767)1, 2, 3 Tanahashi H. and Tabira T. (1999)
    2. Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein. (PubMed id 10574372)1, 2, 9 Tanahashi H. (1999)
    3. Mint3 enhances the activity of hypoxia-inducible fact or-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HI F-1. (PubMed id 19726677)1, 2 Sakamoto T. and Seiki M. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    6. Mint 3: a ubiquitous mint isoform that does not bind to munc18-1 or -2. (PubMed id 9860131)1, 2 Okamoto M. and Suedhof T.C. (1998)
    7. Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network. (PubMed id 18544638)1, 9 Han J....Chi C. (2008)
    8. Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. (PubMed id 17959829)1, 9 Shrivastava-Ranjan P....Kahn R.A. (2008)
    9. Novel mediators of amyloid precursor protein signalin g. (PubMed id 20016085)1, 9 Swistowski A....Bredesen D.E. (2009)
    10. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)

    External Searches for APBA3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing APBA3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9546 HGNC: 580 AceView: APBA3 Ensembl:ENSG00000011132 euGenes: HUgn9546
    ECgene: APBA3 H-InvDB: APBA3

    Other Databases showing APBA3 gene

    (According to HUGE)
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    Specialized Databases showing APBA3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for APBA3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for APBA3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for APBA3 gene:
    Search GeneIP for patents involving APBA3

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