Aliases for APBA3 Gene
External Ids for APBA3 Gene
Previous GeneCards Identifiers for APBA3 Gene
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]
GeneCards Summary for APBA3 Gene
APBA3 (Amyloid Beta Precursor Protein Binding Family A Member 3) is a Protein Coding gene. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. GO annotations related to this gene include enzyme binding and beta-amyloid binding. An important paralog of this gene is APBA1.
UniProtKB/Swiss-Prot for APBA3 Gene
May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.