APBA1 Gene
protein-coding GIFtS: 55
GCID: GC09M072042
|
|
amyloid beta (A4) precursor protein-binding, family A, member...
(Previous symbol: MINT1)
| |
Aliases
for APBA1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 11 2 | | X11A2 | | MINT11 2 3 5 | | X11ALPHA2 | | X111 2 3 5 | | Adaptor Protein X11alpha2 | | D9S411E1 2 5 | | Amyloid Beta (A4) Precursor Protein-Binding, Family A, Member 1 (X11)2 | | Adapter Protein X11alpha2 3 | | Amyloid Beta A4 Precursor Protein-Binding Family A Member 12 | | Neuron-Specific X11 Protein2 3 | | Mint-13 | | Neuronal Munc18-1-Interacting Protein 12 3 | | Phosphotyrosine-Binding/-Interacting Domain (PTB)-Bearing Protein2 | | LIN102 5 | | Mint-13 |
Export aliases for APBA1 gene to outside databasesPrevious GC identifers: GC09M063089 GC09M063901 GC09M065615 GC09M067502 GC09M069274 GC09M071235 GC09M041881 |
Summaries
for APBA1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for APBA1:
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interactswith the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolyticAPP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This geneproduct is believed to be involved in signal transduction processes. It is also regarded as a putative vesiculartrafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis toneuronal cell adhesion. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: APBA1_HUMAN, Q02410Function: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of thesynaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and henceformation of beta-APP
Gene Wiki entry for APBA1
|
Genomic Views
for APBA1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the APBA1 gene promoter:
E2F-4 E2F-3a E2F-5 AP-1 ATF-2 MyoD E2F-2 E2F-1 E2F c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for APBA1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APBA1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q13-q21.1 Ensembl cytogenetic band: 9q21.12 HGNC cytogenetic band: 9q13-q21APBA1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M072042: view genomic region
(about GC identifiers)
Start:
|
72,042,449 bp from pter |
End:
|
72,287,275 bp from pter |
Size:
|
244,827 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr9-,PATCHES 72,050,667-72,099,278 |
|
Proteins
for APBA1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: APBA1_HUMAN, Q02410 (See
protein sequence)Recommended Name: Amyloid beta A4 precursor protein-binding family A member 1 Size: 837 amino acids; 92865 Da
Subunit: Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specificheterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein(APP). Interacts (via PDZ 1 and 2 domains) with FSPB
Subcellular location: Nucleus
6/8 PDB 3D structures from  and Proteopedia  for APBA1 (see all 8):1AQC (3D)
1U37 (3D)
1U38 (3D)
1U39 (3D)
1U3B (3D)
1X11 (3D)
Secondary accessions: O14914 O60570 Q5VYR8Explore the universe of human proteins at neXtProt for APBA1: NX_Q02410
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q02410
APBA1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001154.2
ENSEMBL proteins: ENSP00000265381
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
APBA1 for ontologies About GeneDecksing
APBA1 Antibody Products:
Assay Products for APBA1: |
Protein
Domains /
Families
for APBA1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
APBA1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q02410ProtoNet protein and cluster: Q02410 2 Blocks protein families: IPB001478 PDZ/DHR/GLGF domain IPB006020 Phosphotyrosine interaction domain
UniProtKB/Swiss-Prot: APBA1_HUMAN, Q02410Domain: Composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain(PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminalPDZ domains thought to attach proteins to the plasma membraneDomain: The Autoinhibitory helix linker occludes the APP binding site (By similarity)Similarity: Contains 2 PDZ (DHR) domainsSimilarity: Contains 1 PID domain |
Function
for APBA1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: APBA1_HUMAN, Q02410Function: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of thesynaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and henceformation of beta-APP
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APBA1
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APBA1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
APBA1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for APBA1: Apba1tm1Amor Apba1tm1.1Sud
6 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Apba1):
APBA1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for APBA1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeleton remodeling Neurofilaments | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for APBA1
APBA1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for APBA1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/25 Interacting proteins for APBA1 (Q024101, 2, 3 ENSP000002653814) via UniProtKB, MINT, STRING, and/or I2D (see all 25)About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table
APBA1 for ontologies About GeneDecksing
|
Drugs & Compounds
for APBA1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
APBA1 for compounds About GeneDecksing
 Browse Tocris compounds for APBA1
1 Novoseek chemical compound relationship for APBA1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| phosphotyrosine |
65.7 |
6 |
9822620 (2), 18575606 (1), 8887653 (1) |
Search CenterWatch for drugs/clinical trials and news about APBA1
|
Transcripts
for APBA1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for APBA1 gene: NM_001163.3 Unigene Cluster for APBA1: Amyloid beta (A4) precursor protein-binding, family A, member 1 Hs.171939 [show with all ESTs]Unigene Representative Sequence: NM_0011632 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000265381(uc004ahh.2) ENST00000470082
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APBA1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APBA1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: APBA1 (NM_001163) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for APBA1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APBA1 |
Additional cDNA sequence: AF029106.1 AF047347.1 AL713639.1 L04953.1 5 DOTS entries: DT.97839167 DT.210563 DT.91750255 DT.91688876 DT.100737946 24/29 AceView cDNA sequences (see all 29): NM_001163 AI075072 BF435835 BQ285938 BX507808 BQ269294 AI289020 BM689397 AF029106 AA860795 AF047347 BV204962 BM857518 T28886 L04953 AI989967 BF056458 BM510765 BE645317 BM511013 BE463483 BM857742 AW235364 T03550
GeneLoc Exon Structure
|
Expression
for APBA1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| APBA1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTCTCCTTC
About this image
See APBA1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for APBA1
SOURCE GeneReport for Unigene cluster: Hs.171939
UniProtKB/Swiss-Prot: APBA1_HUMAN, Q02410Tissue specificity: Brain and spinal cord
SABiosciences Expression via Pathway-Focused PCR Arrays including APBA1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APBA1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat APBA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APBA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APBA1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APBA1 |
Orthologs
for APBA1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for APBA1 gene from 6/21 species (see all 21) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
APBA11 |
amyloid beta (A4) precursor protein-binding, family more |
77.53(n)
88.32(a) |
|
427246 XM_424829.3 XP_424829.2 |
lizard
(Anolis carolinensis) |
Reptilia |
APBA16 |
-- |
87(a) |
1 ↔ 1 |
2(49499759-49545416) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.85472 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.07(n) |
|
BG814570.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1000039381 |
amyloid beta A4 precursor protein-binding family A more |
69.5(n)
74.88(a) |
|
100003938 XM_001343336.1 XP_001343372.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
X11L6X11Lbeta6 |
X11Lbeta |
24(a)13(a) |
many ↔ manymany ↔ many |
X(17493641-17500912) X(10521770-10604900) |
worm
(Caenorhabditis elegans) |
Secernentea |
lin-103 |
Phosphotyrosine interaction domain
(PTB/PID)., more |
55(a) |
|
I(8118196-8127374) -- |
ENSEMBL Gene Tree for APBA1 (if available)
TreeFam Gene Tree for APBA1 (if available) |
Paralogs
for APBA1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for APBA1 gene
- APBA22 APBA32
2 SIMAP similar genes for APBA1 using alignment to 1 protein entry: APBA1_HUMAN:APBA3 APBA2
APBA1 for paralogs About GeneDecksing
|
Genomic Variants
for APBA1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for APBA1 (72042449 - 72287275 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 26 variations for APBA1
15/26 CNVs (see all 26): 52848 30331 29801 96102 70721 83052 37778 1827 52850 36962 59536 83053 52847 53726 2822 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing APBA1 |
|
Disorders
/ Diseases
for APBA1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
APBA1 for disorders About GeneDecksing
OMIM gene information: 602414
OMIM disorders: --
8  diseases for APBA1: About MalaCardsalzheimer's disease neuronitis neuronal intranuclear inclusion disease friedreich ataxia
ulcerative colitis brain disease ataxia colorectal cancer
1 disease from the University of Copenhagen DISEASES database for APBA1:Alzheimer's disease 2 Novoseek disease relationships for APBA1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| alzheimers disease |
62.7 |
3 |
16545469 (1), 9614075 (1), 11115513 (1) |
| brain diseases |
41.7 |
1 |
9614075 (1) |
Human Genome Epidemiology (HuGE) Navigator: APBA1 (2 documents)
Export disorders for APBA1 gene to outside databases
|
Publications
for APBA1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for APBA1 gene, integrated from 9 sources (see all 57):
(articles sorted by number of sources associating them with APBA1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system. (PubMed id 7678331)1, 2, 3 Duclos F.... Mandel J.-L. (1993)
- The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. (PubMed id 9614075)1, 2, 9 Borg J.-P.... Turner R.S. (1998)
- The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein. (PubMed id 8887653)1, 2, 9 Borg J.-P.... Margolis B. (1996)
- Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain. (PubMed id 9321393)1, 2, 9 Zhang Z.... Kuriyan J. (1997)
- An X11alpha/FSBP complex represses transcription of t he GSK3beta gene promoter. (PubMed id 20531236)1, 2 Lau K.F....Miller C.C. (2010)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- Mints, Munc18-interacting proteins in synaptic vesicle exocytosis. (PubMed id 9395480)1, 2 Okamoto M. and Suedhof T.C. (1997)
- Comparison of primary structure of a neuron-specific protein, X11, between human and mouse. (PubMed id 7719031)1, 3 Duclos F. and Koenig M. (1995)
- Modulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains. (PubMed id 11010978)1, 9 Mueller H.T....Turner R.S. (2000)
- X11alpha impairs gamma- but not beta-cleavage of amyloid precursor protein. (PubMed id 14756819)1, 9 King G.D....Turner R.S. (2004)
|
External Searches for APBA1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing APBA1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing APBA1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing APBA1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for APBA1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for APBA1 gene:
Search GeneIP for patents involving APBA1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for APBA1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for APBA1 | | OriGene shRNA RFP for APBA1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for APBA1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for APBA1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for APBA1 | | OriGene 3'-UTR Clone for APBA1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for APBA1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for APBA1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat APBA1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing APBA1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat APBA1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat APBA1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat APBA1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat APBA1 |
| |
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| |  |  |  |  | | | | |
 |
 |
 |
 | | | APBA1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for APBA1 |
|  |  |  | | | | ThermoFisher Antibodies for APBA1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat APBA1 |
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