AP4S1 Gene
protein-coding GIFtS: 53
GCID: GC14P031494
|
|
adaptor-related protein complex 4, sigma 1 subunit
| |
Aliases
for AP4S1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Adaptor-Related Protein Complex 4, Sigma 1 Subunit1 2 | | AP-4 Complex Subunit Sigma-12 | | AP47B1 2 | | Clathrin-Associated/Assembly/Adaptor Protein, Sigma 42 | | CLA201 2 | | Sigma-4-Adaptin1 | | SPG521 2 | | Sigma-4-Adaptin1 | | AP-4 Adapter Complex Subunit Sigma-12 3 | | Sigma4-Adaptin1 | | CLAPS42 | | Adapter-Related Protein Complex 4 Subunit Sigma-13 | | CPSQ62 | | Sigma-1 Subunit Of AP-43 |
Export aliases for AP4S1 gene to outside databasesPrevious GC identifers: GC14P028870 GC14P025282 GC14P029484 GC14P030564 GC14P011612 |
Summaries
for AP4S1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AP4S1:
This gene encodes a member of the adaptor complexes small subunit protein family. These proteins are components of theheterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways bymediating vesicle formation and sorting of integral membrane proteins. The encoded protein is the small subunit ofadaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Mutations in thisgene are associated with spastic quadriplegic cerebral palsy-6. Alternatively spliced transcript variants encodingmultiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm ofchromosome 6. (provided by RefSeq, Dec 2011)
UniProtKB/Swiss-Prot: AP4S1_HUMAN, Q9Y587Function: Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteinsfrom the trans-Golgi network (TGN) to the endosomal-lysosomal system
Gene Wiki entry for AP4S1
|
Genomic Views
for AP4S1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AP4S1 gene promoter:
Lmo2 Cdc5 Meis-1b E47 FOXL1 CREB deltaCREB Chx10 Meis-1a Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for AP4S1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AP4S1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q12 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q12AP4S1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P031494: view genomic region
(about GC identifiers)
Start:
|
31,494,312 bp from pter |
End:
|
31,562,818 bp from pter |
Size:
|
68,507 bases |
Orientation:
|
plus strand |
|
Proteins
for AP4S1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AP4S1_HUMAN, Q9Y587 (See
protein sequence)Recommended Name: AP-4 complex subunit sigma-1 Size: 144 amino acids; 17005 Da
Subunit: Adapter-like complex 4 (AP-4) is a heterotetramer composed of two large adaptins (epsilon-type subunit AP4E1and beta-type subunitAP4B1), a medium adaptin (mu-type subunit AP4M1) and a small adaptin (sigma-type AP4S1)
Subcellular location: Golgi apparatus, trans-Golgi network. Membrane, coated pit. Note=Associated with the trans-Golginetwork. Found in soma and dendritic shafts of neuronal cells
Secondary accessions: Q6IAQ4 Q9BVE7Alternative splicing: 2 isoforms: Q9Y587-1 Q9Y587-2 Explore the universe of human proteins at neXtProt for AP4S1: NX_Q9Y587
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y587
AP4S1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001121598.1 NP_001241655.1 NP_001241656.1 NP_001241657.1 NP_001241658.1 NP_009008.2
ENSEMBL proteins: ENSP00000451479 ENSP00000438170 ENSP00000451918 ENSP00000216366 ENSP00000334484 ENSP00000452383 ENSP00000450768 ENSP00000451609 ENSP00000451614 ENSP00000322508
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
AP4S1 for ontologies About GeneDecksing
AP4S1 Antibody Products:
Assay Products for AP4S1: |
Protein
Domains /
Families
for AP4S1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AP4S1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y587ProtoNet protein and cluster: Q9Y587 1 Blocks protein family: IPB000804 Clathrin adaptor complex
UniProtKB/Swiss-Prot: AP4S1_HUMAN, Q9Y587Similarity: Belongs to the adaptor complexes small subunit family |
Function
for AP4S1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: AP4S1_HUMAN, Q9Y587Function: Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteinsfrom the trans-Golgi network (TGN) to the endosomal-lysosomal system
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AP4S1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AP4S1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP4S1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
AP4S1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for AP4S1:
|
Pathways & Interactions
for AP4S1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lysosome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for AP4S1):
AP4S1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AP4S1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/6 Interacting proteins for AP4S1 (Q9Y5873 ENSP000002163664) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006810 | transport |
-- | -- |
AP4S1 for ontologies About GeneDecksing
|
Drugs & Compounds
for AP4S1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AP4S1
Search CenterWatch for drugs/clinical trials and news about AP4S1
|
Transcripts
for AP4S1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AP4S1 gene (6 alternative transcripts): NM_001128126.2 NM_001254726.1 NM_001254727.1 NM_001254728.1 NM_001254729.1 NM_007077.4 Unigene Cluster for AP4S1: Adaptor-related protein complex 4, sigma 1 subunit Hs.293411 [show with all ESTs]Unigene Representative Sequence: NM_00125472810 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000557346 ENST00000542754(uc021rry.1 uc001wqy.4 uc021rrz.1)
ENST00000556232 ENST00000216366(uc001wqx.4 uc010amh.3 uc001wqw.4)
ENST00000334725 ENST00000554609 ENST00000554345 ENST00000555417 ENST00000556480
ENST00000313566
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AP4S1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AP4S1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): AP4S1 (NM_007077) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AP4S1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AP4S1 |
Additional cDNA sequence: AB030654.1 AF155159.1 AK056928.1 AK098330.1 AK304115.1 AK316517.1 BC001259.1 BC035622.1 BT006701.1 BX247969.1 CR457100.1 14 DOTS entries: DT.101969372 DT.308587 DT.109846 DT.100664313 DT.100799358 DT.100734802 DT.308586 DT.428203 DT.92419863 DT.95179044 DT.100777131 DT.428202 DT.75133566 DT.95235688 24/100 AceView cDNA sequences (see all 100): CB961235 CR592542 BQ011759 AA732371 BG413419 BX247969 AI349361 CR606742 BX952168 N75507 AI139578 AI628748 BE466450 AA308086 CK300931 BU620136 CR606567 AI570549 BC035622 BG702035 BX449845 AF155159 AI366190 BE088700
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for AP4S1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for AP4S1
|
Expression
for AP4S1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AP4S1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTGTGCTAC
About this image
See AP4S1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AP4S1
SOURCE GeneReport for Unigene cluster: Hs.293411
UniProtKB/Swiss-Prot: AP4S1_HUMAN, Q9Y587Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for AP4S1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AP4S1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AP4S1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AP4S1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AP4S1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP4S1 |
Orthologs
for AP4S1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for AP4S1 gene from 6/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
AP4S11 |
adaptor-related protein complex 4, sigma 1 subunit |
78.94(n)
84.72(a) |
|
423309 XM_421226.3 XP_421226.2 |
lizard
(Anolis carolinensis) |
Reptilia |
AP4S16 |
-- |
66(a) |
1 ↔ 1 |
2(56976601-56992074) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.208862 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.75(n) |
|
BQ897444.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
ap4s11 |
adaptor-related protein complex 4, sigma 1 subunit |
71.9(n)
77.14(a) |
|
368852 NM_001003826.1 NP_001003826.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G197901 |
AP-4 complex subunit sigma |
64.27(n)
56.83(a) |
|
816498 NM_127537.3 NP_179569.1 |
rice
(Oryza sativa) |
Liliopsida |
Os10g03684001 |
hypothetical protein |
59.34(n)
55.32(a) |
|
4348463 NM_001070985.1 NP_001064450.1 |
ENSEMBL Gene Tree for AP4S1 (if available)
TreeFam Gene Tree for AP4S1 (if available) |
Paralogs
for AP4S1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AP4S1 gene
- AP1S32 AP1S12 AP2S12 AP1S22
8 SIMAP similar genes for AP4S1 using alignment to 8 protein entries: AP4S1_HUMAN (see all proteins):DKFZp779P0659 AP1S2 AP1S3 AP1S1 AP2S1 C15orf38-AP3S2
AP3S2 AP3S1
AP4S1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for AP4S1
PGOHUM00000243705
|
Genomic Variants
for AP4S1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AP4S1 (31494312 - 31562818 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for AP4S1
1 CNV: 7031
Human Gene Mutation Database (HGMD): AP4S1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AP4S1 |
|
Disorders
/ Diseases
for AP4S1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AP4S1 for disorders About GeneDecksing
OMIM gene information: 607243
OMIM disorders: --
UniProtKB/Swiss-Prot: AP4S1_HUMAN, Q9Y587
Defects in AP4S1 are the cause of cerebral palsy spastic quadriplegic type 6 (CPSQ6) [MIM:614067]. CPSQ6 is aneurodevelopmental disorder characterized by neonatal hypotonia that progresses to hypertonia and spasticity, andsevere mental retardation with poor or absent speech development
11  diseases for AP4S1: About MalaCardscerebral palsy spasticity cerebritis spastic paraplegia
short stature hypertonia intellectual disability paraplegia
hypotonia malaria neuronitis
Export disorders for AP4S1 gene to outside databases
|
Publications
for AP4S1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AP4S1 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with AP4S1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Adaptor protein complex 4 deficiency causes severe autosomal- recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature. (PubMed id 21620353)1, 2, 3 Abou Jamra R.... Colleaux L. (2011)
- Characterization of a fourth adaptor-related protein complex. (PubMed id 10436028)1, 2, 3 Hirst J.... Robinson M.S. (1999)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PubMed id 18624398)1 Wang J....He F. (2008)
- Large-scale analysis of the human ubiquitin-related p roteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- AP-4, a novel protein complex related to clathrin adaptors. (PubMed id 10066790)1 Dell'Angelica E.C.... Bonifacino J.S. (1999)
|
External Searches for AP4S1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AP4S1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AP4S1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AP4S1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AP4S1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for AP4S1 gene:
Search GeneIP for patents involving AP4S1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AP4S1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for AP4S1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AP4S1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AP4S1 | | | OriGene Protein Over-expression Lysate for AP4S1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AP4S1 | | OriGene 3'-UTR Clone for AP4S1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AP4S1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AP4S1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AP4S1 | | OriGene Custom Protein Services for AP4S1 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AP4S1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AP4S1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AP4S1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AP4S1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AP4S1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AP4S1 |
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| | | | Search Tocris compounds for AP4S1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP4S1 |
|  |  |  | | | | Search ThermoFisher Antibodies for AP4S1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AP4S1 |
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