AP4M1 Gene
protein-coding GIFtS: 52
GCID: GC07P099699
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adaptor-related protein complex 4, mu 1 subunit
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Aliases
for AP4M1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Adaptor-Related Protein Complex 4, Mu 1 Subunit1 2 | | Adaptor-Related Protein Complex AP-4 Mu4 Subunit2 | | MU-41 2 | | AP-4 Complex Subunit Mu-12 | | MU-ARP21 2 | | Mu-Adaptin-Related Protein-22 | | SPG501 2 | | Mu4-Adaptin1 | | Adapter-Related Protein Complex 4 Mu-1 Subunit2 3 | | MUARP23 | | Mu Subunit Of AP-42 3 | | Mu4-Adaptin1 | | Mu-Adaptin-Related Protein 22 3 | | AP-4 Adapter Complex Mu Subunit3 | | Mu41 | | Mu-ARP21 | | CPSQ32 5 | | |
Export aliases for AP4M1 gene to outside databasesPrevious GC identifers: GC07P098233 GC07P099296 GC07P099310 GC07P099343 GC07P099537 GC07P094334 |
Summaries
for AP4M1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for AP4M1:
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexesmedium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins withtyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: AP4M1_HUMAN, O00189Function: Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteinsfrom the trans-Golgi network (TGN) to the endosomal-lysosomal system
Gene Wiki entry for AP4M1
|
Genomic Views
for AP4M1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the AP4M1 gene promoter:
Max1 C/EBPbeta Elk-1 FOXF2 MyoD Tal-1beta E47 SEF-1 (1) Pax-4a c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for AP4M1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AP4M1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1AP4M1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P099699: view genomic region
(about GC identifiers)
Start:
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99,699,130 bp from pter |
End:
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99,707,968 bp from pter |
Size:
|
8,839 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 99,059,249-99,064,921 |
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Proteins
for AP4M1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AP4M1_HUMAN, O00189 (See
protein sequence)Recommended Name: AP-4 complex subunit mu-1 Size: 453 amino acids; 49977 Da
Subunit: Adapter-like complex 4 (AP-4) is a heterotetramer composed of two large adaptins (epsilon-type subunit AP4E1and beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1) and a small adaptin (sigma-type AP4S1).Interacts with the C-terminal domain of GRID2 (By similarity)
Subcellular location: Golgi apparatus, trans-Golgi network. Membrane, coated pit. Note=Associated with the trans-Golginetwork. Found in soma and dendritic shafts of neuronal cells
1 PDB 3D structure from  and Proteopedia  for AP4M1:3L81 (3D)
Secondary accessions: D6W5U1 Q8WV65 Q9UHK9Explore the universe of human proteins at neXtProt for AP4M1: NX_O00189
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O00189
AP4M1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004713.2
ENSEMBL proteins: ENSP00000377625 ENSP00000401613 ENSP00000400598 ENSP00000403663 ENSP00000352603 ENSP00000414286 ENSP00000396928 ENSP00000412185 ENSP00000406106 ENSP00000406676 ENSP00000391585 ENSP00000393723
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
AP4M1 for ontologies About GeneDecksing
AP4M1 Antibody Products:
Assay Products for AP4M1: |
Protein
Domains /
Families
for AP4M1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
AP4M1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O00189ProtoNet protein and cluster: O00189 2 Blocks protein families: IPB000804 Clathrin adaptor complex IPB001392 Clathrin adaptor complex
UniProtKB/Swiss-Prot: AP4M1_HUMAN, O00189Domain: Interacts specifically with tyrosine-based sorting signalsSimilarity: Belongs to the adaptor complexes medium subunit familySimilarity: Contains 1 MHD (mu homology) domain |
Function
for AP4M1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: AP4M1_HUMAN, O00189Function: Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteinsfrom the trans-Golgi network (TGN) to the endosomal-lysosomal system
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AP4M1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AP4M1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: AP4M1 (NM_004722) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AP4M1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AP4M1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP4M1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
AP4M1 for ontologies About GeneDecksing
|
Pathways & Interactions
for AP4M1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lysosome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for AP4M1):
AP4M1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for AP4M1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/57 Interacting proteins for AP4M1 (O001893 ENSP000003526034) via UniProtKB, MINT, STRING, and/or I2D (see all 57)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006810 | transport |
-- | -- | | GO:0006886 | intracellular protein transport |
IEA | -- | | GO:0016192 | vesicle-mediated transport |
IEA | -- |
AP4M1 for ontologies About GeneDecksing
|
Drugs & Compounds
for AP4M1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for AP4M1
Search CenterWatch for drugs/clinical trials and news about AP4M1
|
Transcripts
for AP4M1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for AP4M1 gene: NM_004722.3 Unigene Cluster for AP4M1: Adaptor-related protein complex 4, mu 1 subunit Hs.632317 [show with all ESTs]Unigene Representative Sequence: NM_00472217 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000394061 ENST00000438383 ENST00000445208 ENST00000429084 ENST00000359593(uc011kjg.1 uc010lgl.1 uc003utb.4 uc011kjh.2)
ENST00000439416 ENST00000478501 ENST00000446007 ENST00000421755(uc003utd.3)
ENST00000463195 ENST00000416938(uc003ute.4) ENST00000422582(uc003utf.4)
ENST00000495154 ENST00000479916 ENST00000450807 ENST00000445295 ENST00000489387
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AP4M1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AP4M1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: AP4M1 (NM_004722) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for AP4M1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AP4M1 |
Additional cDNA sequence: AF020796.1 AF155158.1 AK055686.1 AK293590.1 AK296651.1 AK304489.1 AK315782.1 BC012023.1 BC018705.1 Y08387.1 24/26 DOTS entries (see all 26): DT.100767792 DT.450124 DT.100723809 DT.100723808 DT.100876224 DT.121080681 DT.121080714 DT.100723773 DT.91809193 DT.121080549 DT.65286948 DT.97802060 DT.100645712 DT.100723763 DT.40133352 DT.92468297 DT.121080685 DT.92044834 DT.100059865 DT.100059866 DT.121080631 DT.100044202 DT.100670392 DT.100723768 24/133 AceView cDNA sequences (see all 133): BQ953049 CR590642 CR625655 AI313412 AI590538 BI823691 AL583132 CR611943 AL561446 BC018705 BI823458 CB150140 BX431945 AL554598 BM803268 AW780243 BU677515 CR625474 CR595500 BQ944961 BI766320 BU554045 NM_004722 CR621800
GeneLoc Exon Structure
|
Expression
for AP4M1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| AP4M1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGGCAATGCC
About this image
See AP4M1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for AP4M1
SOURCE GeneReport for Unigene cluster: Hs.632317
UniProtKB/Swiss-Prot: AP4M1_HUMAN, O00189Tissue specificity: Ubiquitous. Highly expressed in testis and lowly expressed in brain and lung
SABiosciences Custom PCR Arrays for AP4M1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AP4M1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat AP4M1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AP4M1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AP4M1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP4M1 |
Orthologs
for AP4M1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for AP4M1 gene from 4/16 species (see all 16) About this table
ENSEMBL Gene Tree for AP4M1 (if available)
TreeFam Gene Tree for AP4M1 (if available) |
Paralogs
for AP4M1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for AP4M1 gene
- AP3M12 AP1M22 AP3M22 AP2M12 AP1M12
4 SIMAP similar genes for AP4M1 using alignment to 11 protein entries: AP4M1_HUMAN (see all proteins):DKFZp686E11263 AP2M1 AP1M2 AP1M1
AP4M1 for paralogs About GeneDecksing
|
Genomic Variants
for AP4M1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for AP4M1 (99699130 - 99707968 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for AP4M1
1 CNV: 2104
Human Gene Mutation Database (HGMD): AP4M1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AP4M1 |
|
Disorders
/ Diseases
for AP4M1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
AP4M1 for disorders About GeneDecksing
OMIM gene information: 602296
OMIM disorders: 612936
UniProtKB/Swiss-Prot: AP4M1_HUMAN, O00189
Defects in AP4M1 are the cause of cerebral palsy spastic quadriplegic type 3 (CPSQ3) [MIM:612936]. Anon-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system.Affected individuals present postnatally with early infantile hypotonia, delayed psychomotor development, strabismus,lack of independent walking and severe mental retardation. They develop progressive spasticity of all limbs withgeneralized hypertonia, hyperreflexia, and extensor plantar responses by the end of the first year of life. Speech isabsent or limited. Pseudobulbar signs, such as drooling, stereotypic laughter, and exaggerated jaw jerk, are part ofthe clinical picture
18  diseases for AP4M1: About MalaCardscerebral palsy, spastic quadriplegic, 3 frontal sinusitis acute frontal sinusitis cerebral palsy
infantile hypotonia hypertonia quadriplegia spasticity
sinusitis hypotonia strabismus cerebritis
malaria neuronitis spastic paraplegia intellectual disability
short stature paraplegia
2 diseases from the University of Copenhagen DISEASES database for AP4M1:Cerebral palsy Quadriplegia Export disorders for AP4M1 gene to outside databases
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Publications
for AP4M1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for AP4M1 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with AP4M1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of two new mu-adaptin-related proteins, mu-ARP1 and mu-ARP2. (PubMed id 9013859)1, 2, 3, 9 Wang X. and Kilimann M.W. (1997)
- Adaptor protein complex 4 deficiency causes severe autosomal- recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature. (PubMed id 21620353)1, 3 Abou Jamra R.... Colleaux L. (2011)
- Mutation in the AP4M1 gene provides a model for neuro axonal injury in cerebral palsy. (PubMed id 19559397)1, 2 Verkerk A.J....Mancini G.M. (2009)
- Signal-binding specificity of the mu4 subunit of the adaptor protein complex, AP-4. (PubMed id 11139587)1, 2 Aguilar R.C.... Bonifacino J.S. (2001)
- AP-4, a novel protein complex related to clathrin adaptors. (PubMed id 10066790)1, 3 Dell'Angelica E.C.... Bonifacino J.S. (1999)
- Characterization of a fourth adaptor-related protein complex. (PubMed id 10436028)1, 2 Hirst J.... Robinson M.S. (1999)
- AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells. (PubMed id 11802162)1, 9 Simmen T....Hunziker W. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4. (PubMed id 18341993)1 Matsuda S....Yuzaki M. (2008)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
|
External Searches for AP4M1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing AP4M1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing AP4M1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing AP4M1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for AP4M1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for AP4M1 gene:
Search GeneIP for patents involving AP4M1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for AP4M1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for AP4M1 | | OriGene shRNA RFP for AP4M1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for AP4M1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for AP4M1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for AP4M1 | | OriGene 3'-UTR Clone for AP4M1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for AP4M1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for AP4M1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for AP4M1 | | OriGene Custom Protein Services for AP4M1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat AP4M1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing AP4M1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AP4M1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AP4M1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AP4M1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AP4M1 |
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| |  |  |  |  | | | | |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat AP4M1 |
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