Aliases for AP3S1 Gene
External Ids for AP3S1 Gene
Previous Symbols for AP3S1 Gene
GeneCards Summary for AP3S1 Gene
AP3S1 (Adaptor-Related Protein Complex 3, Sigma 1 Subunit) is a Protein Coding gene. Among its related pathways are Lysosome and Clathrin derived vesicle budding. GO annotations related to this gene include transporter activity and protein transporter activity. An important paralog of this gene is AP3S2.
UniProtKB/Swiss-Prot for AP3S1 Gene
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals