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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AP3M2 Gene

protein-coding   GIFtS: 52
GCID: GC08P042027

adaptor-related protein complex 3, mu 2 subunit

 Explore 3 diseases affiliated with
AP3M2 via our new
 Human Malady Compendium 
Biological research products
for AP3M2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Adaptor-Related Protein Complex 3, Mu 2 Subunit1 2     P47B2 3
AP47B1 2     HA1 47 KDa Subunit Homolog 22 3
CLA201 2     AP-3 Complex Subunit Mu-22
Adapter-Related Protein Complex 3 Mu-2 Subunit2 3     Clathrin-Associated Protein AP47 Homolog 22
Clathrin Assembly Protein Assembly Protein Complex 1 Medium Chain Homolog 22 3     HA1 47kDA Subunit Homolog 22
Clathrin Coat Assembly Protein AP47 Homolog 22 3     Mu3B-Adaptin1
Clathrin Coat-Associated Protein AP47 Homolog 22 3     Mu3B-Adaptin1
Golgi Adaptor AP-1 47 KDa Protein Homolog 22 3     

External Ids:    HGNC: 5701   Entrez Gene: 109472   Ensembl: ENSG000000707187   OMIM: 6104695   UniProtKB: P536773   

Export aliases for AP3M2 gene to outside databases

Previous GC identifers: GC08P041394 GC08P042039 GC08P041751 GC08P042129 GC08P040537


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AP3M2:
This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the
adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and
specialized organelles. Multiple alternatively spliced variants, encoding the same protein, have been identified.
(provided by RefSeq, Aug 2008)

UniProtKB/Swiss-Prot: AP3M2_HUMAN, P53677
Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is
associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from
the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3
is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.1  NT_167187.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AP3M2 gene promoter:
         MIF-1   LCR-F1   YY1   E47   c-Ets-1   S8   SRY   PPAR-gamma1   Nkx6-1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidAP3M2 promoter sequence
   Search SABiosciences Chromatin IP Primers for AP3M2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AP3M2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p11.2   Ensembl cytogenetic band:  8p11.21   HGNC cytogenetic band: 8p11.2

AP3M2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AP3M2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P042027:  view genomic region     (about GC identifiers)

Start:
42,010,464 bp from pter      End:
42,029,191 bp from pter
Size:
18,728 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AP3M2_HUMAN, P53677 (See protein sequence)
Recommended Name: AP-3 complex subunit mu-2  
Size: 418 amino acids; 46977 Da
Subunit: AP-3 associates with the BLOC-1 complex (By similarity). Adaptor protein complex 3 (AP-3) is a heterotetramer
composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin
(mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2)
Subcellular location: Golgi apparatus
Secondary accessions: B2RCR0 D3DSY2

Explore the universe of human proteins at neXtProt for AP3M2: NX_P53677

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P53677

  • AP3M2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001127768.1  NP_006794.1  

    ENSEMBL proteins: 
     ENSP00000428787   ENSP00000430200   ENSP00000380132   ENSP00000430616   ENSP00000431918  
     ENSP00000429515   ENSP00000430538   ENSP00000429435   ENSP00000429037   ENSP00000428279  
     ENSP00000429804   ENSP00000174653  

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    Novus Biologicals AP3M2 Lysate
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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus IEA--
    GO:0030119AP-type membrane coat adaptor complex TAS8076832
    GO:0030131clathrin adaptor complex IEA--


    AP3M2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    AP3M2 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR018240 Clathrin_mu_CS
     IPR001392 Clathrin_mu
     IPR008968 Clathrin_mu_C
     IPR022775 AP_mu_sigma_su
     IPR011012 Longin-like_dom

    Graphical View of Domain Structure for InterPro Entry P53677

    ProtoNet protein and cluster: P53677

    2 Blocks protein families:
    IPB000804 Clathrin adaptor complex
    IPB001392 Clathrin adaptor complex


    UniProtKB/Swiss-Prot: AP3M2_HUMAN, P53677
    Similarity: Belongs to the adaptor complexes medium subunit family
    Similarity: Contains 1 MHD (mu homology) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: AP3M2_HUMAN, P53677
    Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is
    associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from
    the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3
    is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals

    miRNA
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    miRTarBase miRNAs that target AP3M2:
    hsa-mir-122 (MIRT003104)

    OriGene 3'-UTR Clone (see all 2): AP3M2
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    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate AP3M2 (see all 16):
    hsa-miR-623 hsa-miR-548p hsa-miR-7-2* hsa-miR-146a hsa-miR-545 hsa-miR-1205 hsa-miR-192 hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmidAP3M2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP3M2

    Animal Models:
         Mouse knock-out Ap3m2tm1Ohno for AP3M2
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ap3m2):
     behavior/neurological  nervous system 

    AP3M2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Lysosome
    Lysosome1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for AP3M2):
        Lysosome


    AP3M2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AP3M2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/42 Interacting proteins for AP3M2 (P536773 ENSP000001746534) via UniProtKB, MINT, STRING, and/or I2D (see all 42)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHABP319463I2D: score=1 
    AFTPHENSP000002388554STRING: ENSP00000238855
    AP1G1ENSP000003771484STRING: ENSP00000377148
    AP1G2ENSP000003124424STRING: ENSP00000312442
    AP1S1ENSP000003366664STRING: ENSP00000336666
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0006886intracellular protein transport IEA--
    GO:0008089anterograde axon cargo transport ISS--
    GO:0016192vesicle-mediated transport ----
    GO:0048490anterograde synaptic vesicle transport ISS--


    AP3M2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AP3M2
    Search CenterWatch for drugs/clinical trials and news about AP3M2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AP3M2 gene (2 alternative transcripts): 
    NM_001134296.1  NM_006803.3  

    Unigene Cluster for AP3M2:

    Adaptor-related protein complex 3, mu 2 subunit
    Hs.654529  [show with all ESTs]
    Unigene Representative Sequence: NM_001134296
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000518421(uc003xop.3) ENST00000517865(uc003xoq.2) ENST00000396926
    ENST00000520685 ENST00000521280 ENST00000530375 ENST00000522288 ENST00000521235
    ENST00000517969 ENST00000517922 ENST00000523249 ENST00000517499 ENST00000521899
    ENST00000522320 ENST00000522606 ENST00000520689 ENST00000174653(uc003xoo.3 uc010lxe.3)


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    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate AP3M2 (see all 16):
    hsa-miR-623 hsa-miR-548p hsa-miR-7-2* hsa-miR-146a hsa-miR-545 hsa-miR-1205 hsa-miR-192 hsa-miR-1184
    SwitchGear 3'UTR luciferase reporter plasmidAP3M2 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AK315228.1 BC021966.2 BC056257.1 BC056398.1 BX648354.1 BX648390.1 D38293.1 

    14 DOTS entries:

    DT.100723186  DT.416984  DT.75105633  DT.95169003  DT.120635675  DT.91673615  DT.91748851  DT.100669543 
    DT.40250523  DT.416986  DT.91723391  DT.100783099  DT.120635677  DT.100783097 

    24/213 AceView cDNA sequences (see all 213):

    CD105799 BC056398 D38713 AW583345 AW132094 AI434968 AA331409 BX648354 
    CA310340 AU143402 AA705505 CR610500 AU132048 AA310729 AI052085 BC021966 
    AW674468 T07294 BQ942738 BM468708 BM698153 CA414535 AL705978 CB853501 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for AP3M2 (see all 10)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b · 12c
    SP1:              -     -                       -                       -                       -     -                                             
    SP2:              -     -     -                 -                       -                       -     -                                             
    SP3:              -     -     -     -     -     -                       -                       -     -                                             
    SP4:                                            -                       -                       -     -     -     -                                 
    SP5:                                                                                            -     -                                             


    ECgene alternative splicing isoforms for AP3M2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AP3M2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGCAGAAGTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See AP3M2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AP3M2

    SOURCE GeneReport for Unigene cluster: Hs.654529
        SABiosciences Custom PCR Arrays for AP3M2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AP3M2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for AP3M2 gene from 8/30 species (see all 30)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves AP3M21 adaptor-related protein complex 3, mu 2 subunit 83.81(n)
    96.65(a)
      426790  XM_424403.3  XP_424403.2 
    lizard
    (Anolis carolinensis)
    Reptilia AP3M26
    --
    98(a)
    1 ↔ 1
    GL343545.1(287761-295500)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.324232 Xenopus laevis transcribed sequence with strong similarity more 80.85(n)    BX846221.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ap3m21 adaptor-related protein complex 3, mu 2 subunit 77.11(n)
    91.15(a)
      415244  NM_001002154.1  NP_001002154.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta cm1 , 3 ommochrome biosynthesis3
    carmine1
    69(a)3
    65.22(n)1
    70.29(a)1
      1 6E43
    316471  NM_176700.21  NP_788873.11 
    worm
    (Caenorhabditis elegans)
    Secernentea apm-36
    AdaPtin, Mu/medium chain (clathrin associated comp...
    63(a)
    1 → many
    X(954932-957760)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ZIP41 clathrin adaptor complexes medium subunit-like protein 50.16(n)
    44.66(a)
      842113  NM_104536.4  NP_176052.3 
    rice
    (Oryza sativa)
    Liliopsida Os05g03831001 hypothetical protein 50.28(n)
    43.1(a)
      4338648  NM_001061945.1  NP_001055410.1 


    ENSEMBL Gene Tree for AP3M2 (if available)
    TreeFam Gene Tree for AP3M2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for AP3M2 gene
    AP3M12  AP4M12  AP1M22  AP2M12  AP1M12  
    5 SIMAP similar genes for AP3M2 using alignment to 9 protein entries:     AP3M2_HUMAN (see all proteins):
    AP3M1    DKFZp586G1518    AP1M1    AP1M2    AP2M1

    AP3M2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for AP3M2
    PGOHUM00000236203


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/386 NCBI SNPs in AP3M2 are shown (see all 386    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs117838641,2
    C,A,H,--42008489(+) GCCTCT/CTGGGT 2 -- us2k12Minor allele frequency- C:0.25NA CSA 4
    rs1811879921,2
    --42008510(+) CTCCCA/GTCTCA 2 -- us2k10--------
    rs1861677131,2
    --42008548(+) ACGTGA/CCATCA 2 -- us2k10--------
    rs1888736541,2
    --42008596(+) TTCATC/GATGTT 2 -- us2k10--------
    rs1462448231,2
    --42008618(+) TCTTGA/CACTCC 2 -- us2k10--------
    rs1506146021,2
    C,--42008695(+) CCCAG-/CTCCAAG 2 -- us2k10--------
    rs1820652121,2
    --42008698(+) AGCTCC/GAAGAG 2 -- us2k10--------
    rs1112393491,2
    --42008759(+) CCTGGC/TGCATG 2 -- us2k12Minor allele frequency- T:0.05CSA WA 120
    rs1379816081,2
    --42008761(+) TGGCGC/TATGGT 2 -- us2k10--------
    rs1864012191,2
    --42008992(+) ATCTAC/TCCCTG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for AP3M2 (42010464 - 42029191 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for AP3M2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    AP3M2 for disorders           About GeneDecksing

    OMIM gene information: 610469    OMIM disorders: --

    3 diseases for AP3M2:    About MalaCards
    hermansky-pudlak syndrome    endocarditis    schizophrenia

    Human Genome Epidemiology (HuGE) Navigator: AP3M2 (2 documents)

    Export disorders for AP3M2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for AP3M2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with AP3M2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of 115 human chromosome 8-specific expressed-sequence tags by exon amplification. (PubMed id 7601449)1, 2, 3 Koyama K.... Nakamura Y. (1995)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
    4. Human immunodeficiency virus type-1 gag and host vesic ular trafficking pathways. (PubMed id 20012524)1 Chu H....Spearman P. (2009)
    5. Association analysis between schizophrenia and the AP -3 complex genes. (PubMed id 19481122)1 Hashimoto R....Kunugi H. (2009)
    6. HIV-1 Vpu inhibits accumulation of the envelope glycop rotein within clathrin-coated, Gag-containing endosomes. (PubMed id 18076669)1 Van Damme N. and Guatelli J. (2008)
    7. Mutation screening of AP3M2 in Japanese epilepsy patients. (PubMed id 17293072)1 Huang M.C....Kojima T. (2007)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family. (PubMed id 9400603)1 Ohno H....Bonifacino J.S. (1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10947 HGNC: 570 AceView: AP3M2 Ensembl:ENSG00000070718 euGenes: HUgn10947
    ECgene: AP3M2 Kegg: 10947 H-InvDB: AP3M2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AP3M2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AP3M2 gene:
    Search GeneIP for patents involving AP3M2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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