External Ids for AOAH Gene
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
GeneCards Summary for AOAH Gene
AOAH (Acyloxyacyl Hydrolase (Neutrophil)) is a Protein Coding gene. GO annotations related to this gene include lipoprotein lipase activity and acyloxyacyl hydrolase activity.
UniProtKB/Swiss-Prot for AOAH Gene
Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides