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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

AOAH Gene

protein-coding   GIFtS: 55
GCID: GC07M036519

Acyloxyacyl Hydrolase (Neutrophil)

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Acyloxyacyl Hydrolase (Neutrophil)1 2
Acyloxyacyl Hydrolase2
EC 3.1.1.773

External Ids:    HGNC: 5481   Entrez Gene: 3132   Ensembl: ENSG000001362507   OMIM: 1025935   UniProtKB: P280393   

Export aliases for AOAH gene to outside databases

Previous GC identifers: GC07M036199 GC07M036293 GC07M036325


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for AOAH Gene:
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the
hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying
these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative
bacteria. Alternatively spliced transcript variants have been described.(provided by RefSeq, Apr 2010)

GeneCards Summary for AOAH Gene: 
AOAH (acyloxyacyl hydrolase (neutrophil)) is a protein-coding gene. Diseases associated with AOAH include osteochondrosis, and common cold. GO annotations related to this gene include catalytic activity and acyloxyacyl hydrolase activity.

UniProtKB/Swiss-Prot: AOAH_HUMAN, P28039
Function: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial
lipopolysaccharides

Gene Wiki entry for AOAH Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the AOAH gene promoter:
         COUP-TF1   oct-B3   oct-B2   COUP   HNF-4alpha2   POU2F2   HNF-4alpha1   COUP-TF   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): AOAH promoter sequence
   Search SABiosciences Chromatin IP Primers for AOAH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat AOAH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p14-p12   Ensembl cytogenetic band:  7p14.2   HGNC cytogenetic band: 7p14-p12

AOAH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
AOAH gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M036519:  view genomic region     (about GC identifiers)

Start:
36,552,456 bp from pter      End:
36,764,154 bp from pter
Size:
211,699 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 36,590,357-36,801,982     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AOAH_HUMAN, P28039 (See protein sequence)
Recommended Name: Acyloxyacyl hydrolase precursor  
Size: 575 amino acids; 65105 Da
Subunit: Heterodimer
Subcellular location: Secreted
Secondary accessions: A4D1Y5 B7Z490 Q53F13
Alternative splicing: 2 isoforms:  P28039-1   P28039-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for AOAH: NX_P28039

Explore proteomics data for AOAH at MOPED 

Post-translational modifications:

  • UniProtKB: Both subunits contain a number of cysteine residues that may form disulfide bridges
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P28039

  • AOAH Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    AOAH Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001170977.1  NP_001170978.1  NP_001628.1  

    ENSEMBL proteins: 
     ENSP00000258749   ENSP00000405683   ENSP00000416051   ENSP00000416472   ENSP00000441101  
     ENSP00000439283  

    Human Recombinant Protein Products for AOAH: 
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    OriGene Protein Over-expression Lysate for AOAH
    OriGene MassSpec for AOAH 
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    Novus Biologicals AOAH Proteins
    Novus Biologicals AOAH Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for AOAH 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    AOAH for ontologies           About GeneDecksing



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    LSBio Antibodies in human, mouse, rat for AOAH 

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    Cloud-Clone Corp. CLIAs for AOAH


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5 InterPro protein domains:
     IPR011001 Saposin-like
     IPR013831 SGNH_hydro-type_esterase_dom
     IPR008138 SapB_2
     IPR008139 SaposinB
     IPR001087 Lipase_GDSL

    Graphical View of Domain Structure for InterPro Entry P28039

    ProtoNet protein and cluster: P28039

    2 Blocks protein domains:
    IPB001087 Lipolytic enzyme
    IPB008139 Saposin B


    UniProtKB/Swiss-Prot: AOAH_HUMAN, P28039
    Similarity: Contains 1 saposin B-type domain


    AOAH for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AOAH_HUMAN, P28039
    Function: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial
    lipopolysaccharides
    Catalytic activity: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty
    acid

         Genatlas biochemistry entry for AOAH:
    acyloxyacyl hydrolase,two-subunit lipase expressed in phagocytic cells,specifically hydrolyzing the secondary acyl
    chains of the liposaccharide found in the walls of gram-negative bacteria

         Enzyme Number (IUBMB): EC 3.1.1.771

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity TAS1883828
    GO:0004465lipoprotein lipase activity TAS1883828
    GO:0016788hydrolase activity, acting on ester bonds ----
    GO:0050528acyloxyacyl hydrolase activity IEA--
         
    AOAH for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Aoah):
     immune system 

    AOAH for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Aoahtm1Rsm for AOAH

       inGenious Targeting Laboratory - Custom generated mouse model solutions for AOAH 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for AOAH

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for AOAH 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for AOAH 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AOAH
    1 QIAGEN miScript miRNA Assays for microRNA that regulate AOAH:
    hsa-miR-3673
    SwitchGear 3'UTR luciferase reporter plasmidAOAH 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    OriGene ORF clones in mouse, rat for AOAH
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    GenScript: all cDNA clones in your preferred vector (see all 3): AOAH (NM_001637)
    Sino Biological Human cDNA Clone for AOAH
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                         Customized lentivirus expression plasmids for stable overexpression of AOAH 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for AOAH


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for AOAH

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for AOAH (P280393 ENSP000002587494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IGHG1P018573, ENSP000003749904I2D: score=1 STRING: ENSP00000374990
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006629lipid metabolic process TAS1883828
    GO:0006954inflammatory response TAS1883828
    GO:0008653lipopolysaccharide metabolic process IEA--
    GO:0050728negative regulation of inflammatory response IEA--

    AOAH for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    AOAH for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for AOAH

    1 HMDB Compound for AOAH    About this table
    CompoundSynonyms CAS #PubMed Ids
    WaterDihydrogen oxide (see all 2)7732-18-5--

    1 Novoseek inferred chemical compound relationship for AOAH gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    endotoxin 38.8 2 1987068 (2)

    Search CenterWatch for drugs/clinical trials and news about AOAH

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for AOAH gene (3 alternative transcripts): 
    NM_001177506.1  NM_001177507.1  NM_001637.3  

    Unigene Cluster for AOAH:

    Acyloxyacyl hydrolase (neutrophil)
    Hs.488007  [show with all ESTs]
    Unigene Representative Sequence: NM_001177506
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000258749(uc003tfh.4) ENST00000471806 ENST00000431169(uc022abu.1)
    ENST00000483864 ENST00000491444 ENST00000487014 ENST00000495942 ENST00000480201
    ENST00000543742 ENST00000435386 ENST00000414637 ENST00000535891(uc011kba.2)
    ENST00000538464
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat AOAH
    1 QIAGEN miScript miRNA Assays for microRNA that regulate AOAH:
    hsa-miR-3673
    SwitchGear 3'UTR luciferase reporter plasmidAOAH 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for AOAH
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat AOAH
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    Sirion Biotech Customized lentivirus for stable overexpression of AOAH 
                         Customized lentivirus expression plasmids for stable overexpression of AOAH 
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    OriGene qPCR primer pairs and template standards for AOAH
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat AOAH
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat AOAH

    Additional mRNA sequence: 

    AK223476.1 AK297016.1 AK298644.1 AK308215.1 BC025698.1 M62840.1 

    9 DOTS entries:

    DT.95161135  DT.121109380  DT.75126381  DT.92069026  DT.121109408  DT.213179  DT.40117223  DT.40117351 
    DT.91664621 

    24/51 AceView cDNA sequences (see all 51):

    AW969571 AI825625 AI338008 CB046662 AA311288 AI633804 BG685317 BM925048 
    BI768131 NM_001637 AI423020 N50131 BQ448512 M62840 AA524159 AI356011 
    BC025698 AI935091 AI082606 BI909420 BQ013972 AW614060 AI356010 CD368011 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for AOAH    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24a · 24b
    SP1:                                                                    -     -     -                                                     -                     
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            


    ECgene alternative splicing isoforms for AOAH

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    AOAH expression in normal human tissues (normalized intensities)      AOAH embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACCCCTGGG
    AOAH Expression
    About this image


    AOAH expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Natural Killer Cells Peripheral Blood
     
     Spleen (Hematopoietic System)

    See AOAH Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for AOAH

    SOURCE GeneReport for Unigene cluster: Hs.488007
        SABiosciences Custom PCR Arrays for AOAH
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for AOAH gene from 3/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aoah1 , 5 acyloxyacyl hydrolase1, 5 81.71(n)1
    76.48(a)1
      13 (7.49 cM)5
    270521  NM_012054.31  NP_036184.11 
     207941195 
    chicken
    (Gallus gallus)
    Aves AOAH1 acyloxyacyl hydrolase (neutrophil) 68.05(n)
    63.65(a)
      420737  XM_418835.2  XP_418835.2 
    lizard
    (Anolis carolinensis)
    Reptilia AOAH6
    Uncharacterized protein
    62(a)
    1 ↔ 1
    6(47002640-47088872)


    ENSEMBL Gene Tree for AOAH (if available)
    TreeFam Gene Tree for AOAH (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4588 SNPs in AOAH are shown (see all 4588)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0506634
    ----see VAR_0506632 D N mis40--------
    rs351532581,2
    C--36434901(+) CACAG-/CA/GA 
            
    AAAGT
    3 -- int10--------
    rs801683671,2
    F--36524592(+) TCAAAT/GTATTT 3 -- ds50011Minor allele frequency- G:0.02WA 118
    rs789233101,2
    F--36524708(+) TTATAC/GCCACT 3 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1426878531,2
    --36524755(+) TATTGC/TCATTT 3 -- ds50010--------
    rs598945321,2
    C,F--36524935(+) TGTGTG/AAGTCC 3 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1386253691,2
    C--36525015(+) CACAGC/GGGGGA 3 -- ds50010--------
    rs32097241,2
    C--36525134(-) CCAAAC/AAAAAG 3 -- ut312Minor allele frequency- A:0.00NA 4
    rs755318451,2
    C,F--36525142(+) TGGAAT/CGGCAC 3 -- ut311Minor allele frequency- C:0.03WA 118
    rs79861,2
    C,F,O,H--36525184(-) CCTTCC/TGCTGT 4 P L ut31 mis1 ese334Minor allele frequency- T:0.18MN EA NA NS WA 5259

    HapMap Linkage Disequilibrium report for AOAH (36552456 - 36764154 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for AOAH:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2676624CNV Deletion23128226
    esv2613811CNV Deletion19546169
    nsv5700CNV Insertion18451855
    nsv470199CNV Loss18288195
    nsv464427CNV Loss19166990
    nsv830960CNV Loss17160897
    nsv366801CNV Loss16902084
    nsv830957CNV Gain17160897
    esv33783CNV Gain17666407
    nsv830958CNV Gain17160897


    Human Gene Mutation Database (HGMD): AOAH
    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing AOAH:
    Gastric Cancer
    SeqTarget long-range PCR primers for resequencing AOAH
    DNA2.0 Custom Variant and Variant Library Synthesis for AOAH

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 102593    OMIM disorders: --

    7 diseases for AOAH:    About MalaCards
    osteochondrosis    common cold    mastitis    asthma
    hepatitis b    gastric cancer    hepatitis


    AOAH for disorders           About GeneDecksing

    Genetic Association Database (GAD): AOAH
    Human Genome Epidemiology (HuGE) Navigator: AOAH (3 documents)

    Export disorders for AOAH gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for AOAH gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with AOAH)
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    world of online information

    1. Expression and characterization of recombinant human acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides. (PubMed id 1883828)1, 2, 3, 9 Hagen F.S.... Munford R.S. (1991)
    2. Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes. (PubMed id 16815140)1, 4, 9 Barnes K.C....Mathias R.A. (2006)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Host determinants of HIV-1 control in African America ns. (PubMed id 20205591)1, 4 Pelak K....Weintrob A.C. (2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Adenovirus-mediated transfer of a gene encoding acyloxyacyl hydrolase (AOAH) into mice increases tissue and plasma AOAH activity. (PubMed id 8613354)1, 9 Coulthard M.G....Meidell R.S. (1996)
    7. Intracellular and extracellular enzymatic deacylation of bacterial endotoxin during localized inflammation induced by Escherichia coli. (PubMed id 1987068)1, 9 McDermott C.M....Fenwick B.W. (1991)
    8. Chromosomal localization of the acyloxyacyl hydrolase (AOAH) gene to 7p14-p12 using fluorescence in situ hybridization. (PubMed id 8088847)1, 9 Whitmore T.E....Durnam D.M. (1994)
    9. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    10. Polymorphisms in RYBP and AOAH genes are associated wi th chronic rhinosinusitis in a Chinese population: a replication study. (PubMed id 22723975)1 Zhang Y....Zhang L. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 313 HGNC: 548 AceView: AOAH Ensembl:ENSG00000136250 euGenes: HUgn313
    ECgene: AOAH H-InvDB: AOAH

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for AOAH Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for AOAH gene:
    Search GeneIP for patents involving AOAH

    GeneCards and IP:
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