Aliases for ANXA9 Gene
External Ids for ANXA9 Gene
Previous Symbols for ANXA9 Gene
The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANXA9 Gene
ANXA9 (Annexin A9) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding and phospholipid binding. An important paralog of this gene is ANXA4.
UniProtKB/Swiss-Prot for ANXA9 Gene
Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.