Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ANXA8L2 Gene

protein-coding   GIFtS: 48
GCID: GC10P047746

Annexin A8-Like 2

  See ANXA8L2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Annexin A8-Like 21 2
ANXA82
Annexin A8-Like Protein 22
Annexin A8L22
bA145E20.22

External Ids:    HGNC: 233351   Entrez Gene: 2442   Ensembl: ENSG000001868077   UniProtKB: Q5VT793   

Export aliases for ANXA8L2 gene to outside databases

Previous GC identifers: GC10U900552 GC10P047217 GC10P043018


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ANXA8L2 Gene:
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding
proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the
thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia.
A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ANXA8L2 Gene:
ANXA8L2 (annexin A8-like 2) is a protein-coding gene. Diseases associated with ANXA8L2 include acute promyelocytic leukemia. GO annotations related to this gene include calcium-dependent phospholipid binding and calcium ion binding. An important paralog of this gene is ANXA3.

Gene Wiki entry for ANXA8L2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the ANXA8L2 gene promoter:
         AML1a   p300   MEF-2   GATA-1   YY1   MEF-2A   PPAR-alpha   SEF-1 (1)   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANXA8L2 promoter sequence
   Search Chromatin IP Primers for ANXA8L2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANXA8L2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.22   Ensembl cytogenetic band:  10q11.22   HGNC cytogenetic band: 10q11.22

ANXA8L2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANXA8L2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P047746:  view genomic region     (about GC identifiers)

Start:
47,746,920 bp from pter      End:
47,763,041 bp from pter
Size:
16,122 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: AXA82_HUMAN, Q5VT79 (See protein sequence)
Recommended Name: Annexin A8-like protein 2  
Size: 327 amino acids; 36865 Da
Secondary accessions: B2R939 Q53FY2 Q5VT78 Q96H89
Alternative splicing: 2 isoforms:  Q5VT79-1   Q5VT79-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ANXA8L2: NX_Q5VT79

Explore proteomics data for ANXA8L2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ANXA8L2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001621.2  
    ENSEMBL proteins: 
     ENSP00000339264   ENSP00000363395   ENSP00000440742   ENSP00000407079  

    ANXA8L2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ANXA8L2
    GenScript Custom Purified and Recombinant Proteins Services for ANXA8L2
    Novus Biologicals ANXA8L2 Proteins
    Sino Biological Recombinant Protein for ANXA8L2
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for ANXA8L2
    Cloud-Clone Corp. Proteins for ANXA8L2

     
    Search eBioscience for Proteins for ANXA8L2 

    ANXA8L2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ANXA8L2
    Novus Biologicals ANXA8L2 Antibodies
    Abcam antibodies for ANXA8L2
    Cloud-Clone Corp. Antibodies for ANXA8L2
    Search ThermoFisher Antibodies for ANXA8L2
    LSBio Antibodies in human, mouse, rat for ANXA8L2

    ANXA8L2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ANXA8L2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ANXA8L2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ANXA8L2
    Cloud-Clone Corp. CLIAs for ANXA8L2
    Search eBioscience for ELISAs for ANXA8L2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ANXA: Annexins

    4 InterPro protein domains:
     IPR009115 AnnexinVIII
     IPR018502 Annexin_repeat
     IPR001464 Annexin
     IPR018252 Annexin_repeat_CS

    Graphical View of Domain Structure for InterPro Entry Q5VT79

    ProtoNet protein and cluster: Q5VT79

    UniProtKB/Swiss-Prot: AXA82_HUMAN, Q5VT79
    Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid (By similarity)
    Similarity: Belongs to the annexin family
    Similarity: Contains 4 annexin repeats


    Find genes that share domains with ANXA8L2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005544calcium-dependent phospholipid binding IEA--
         
    Find genes that share ontologies with ANXA8L2           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ANXA8L2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ANXA8L2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANXA8L2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ANXA8L2

    miRNA
    Products:
        
    miRTarBase miRNAs that target ANXA8L2:
    hsa-mir-124-3p (MIRT022354), hsa-let-7b-5p (MIRT032274), hsa-mir-26b-5p (MIRT029043)

    Block miRNA regulation of human, mouse, rat ANXA8L2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ANXA8L2
    SwitchGear 3'UTR luciferase reporter plasmidANXA8L2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ANXA8L2
    Predesigned siRNA for gene silencing in human, mouse, rat ANXA8L2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ANXA8L2

    Clone
    Products:
         
    OriGene clones in human, mouse for ANXA8L2 (see all 7)
    OriGene ORF clones in mouse, rat for ANXA8L2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANXA8L2 (NM_001630)
    Sino Biological Human cDNA Clone for ANXA8L2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANXA8L2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANXA8L2

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ANXA8L2
    Browse ESI BIO Cell Lines and PureStem Progenitors for ANXA8L2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA8L2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    peroxisome2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for ANXA8L2 About    
    See pathways by source

    SuperPathContained pathways About
    1Prostaglandin Synthesis and Regulation
    Prostaglandin Synthesis and Regulation


    1 BioSystems Pathway for ANXA8L2
        Prostaglandin Synthesis and Regulation



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANXA8L2
    Interactions:

        Search GeneGlobe Interaction Network for ANXA8L2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for ANXA8L2 (Q5VT793 ENSP000003633954) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UCHL5Q9Y5K53, ENSP000003564254I2D: score=1 STRING: ENSP00000356425
    ACDENSP000003774964STRING: ENSP00000377496
    TERF1ENSP000002766034STRING: ENSP00000276603
    TERF2IPENSP000003000864STRING: ENSP00000300086
    TINF2ENSP000002674154STRING: ENSP00000267415
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANXA8L2 (AXA82)

    1 HMDB Compound for ANXA8L2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    2 Novoseek inferred chemical compound relationships for ANXA8L2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 51 5 1313714 (2), 8018923 (1)
    calcium 0.785 1 8231235 (1)



    Find genes that share compounds with ANXA8L2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ANXA8L2 gene (2 alternative transcripts): 
    NM_001630.2  NM_001039801.1  

    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340243(uc009xnh.1 uc001jen.3) ENST00000374277(uc001jem.3 uc010qgb.2)
    ENST00000538825 ENST00000449464
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ANXA8L2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ANXA8L2
    SwitchGear 3'UTR luciferase reporter plasmidANXA8L2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ANXA8L2
    Predesigned siRNA for gene silencing in human, mouse, rat ANXA8L2
    Clone
    Products:
         
    OriGene clones in human, mouse for ANXA8L2 (see all 7)
    OriGene ORF clones in mouse, rat for ANXA8L2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANXA8L2 (NM_001630)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANXA8L2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANXA8L2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ANXA8L2
    OriGene qSTAR qPCR primer pairs in human, mouse for ANXA8L2
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ANXA8L2
      QuantiTect SYBR Green Assays in human, mouse, rat ANXA8L2
      QuantiFast Probe-based Assays in human, mouse, rat ANXA8L2

    Selected AceView cDNA sequences (see all 457):

    CR622037 BP373493 BG319547 BF003067 AA252968 BX399166 BU161045 BM910137 
    BM840837 BF108792 BQ011225 BM910692 BM552140 BU686785 BE614822 BM984692 
    BM560354 BQ014733 CA407844 BM849140 BC004376 BM739860 BE645180 BX345650 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ANXA8L2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANXA8L2 Expression
    About this image


    ANXA8L2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Kidney (Urinary System)    fully expand to see all 2 entries
             Renal Collecting Duct System
     
     Lung (Respiratory System)
             Trachea
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Hair (Integumentary System)
             Bulge Stem Cells Bulge
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced embryoid bodies
    ANXA8L2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANXA8L2 Protein Expression
        Custom PCR Arrays for ANXA8L2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ANXA8L2
    OriGene qSTAR qPCR primer pairs in human, mouse for ANXA8L2
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ANXA8L2
    QuantiTect SYBR Green Assays in human, mouse, rat ANXA8L2
    QuantiFast Probe-based Assays in human, mouse, rat ANXA8L2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA8L2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for ANXA8L2 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Anxa85 annexin A8   --   14 (20.80 cM) 34085981 
    chicken
    (Gallus gallus)
    Aves --
    Annexin
    73(a)
    1 → many
    6(17424714-17438731)


    ENSEMBL Gene Tree for ANXA8L2 (if available)
    TreeFam Gene Tree for ANXA8L2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ANXA8L2 gene
    ANXA32  ANXA62  ANXA52  ANXA12  ANXA92  ANXA22  ANXA72  ANXA82  
    ANXA112  ANXA102  ANXA8L12  ANXA42  ANXA132  
    15 SIMAP similar genes for ANXA8L2 using alignment to 3 protein entries:     AXA82_HUMAN (see all proteins):
    ANXA8    ANXA8L1    DKFZp686H02120    ANXA4    ANXA11    ANXA13
    ANXA3    ANXA6    ANXA5    ANXA7    ANXA2    ANXA2P2
    ANXA10    ANXA1    ANXA9

    Find genes that share paralogs with ANXA8L2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ANXA8L2 (see all 117)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2009230461,2
    C--47745002(+) ACTATA/GTGTTG 1 -- us2k10--------
    rs2003818231,2
    --47745234(+) ATTAT-/TATTTTT 1 -- us2k10--------
    rs2012886391,2
    C--47745235(+) ATTAT-/ATTTTT 1 -- us2k10--------
    rs2013964251,2
    C--47745540(+) ATGAAA/TCAGAT 1 -- us2k10--------
    rs1435456381,2
    C--47745660(+) ATACAA/GCTTTC 1 -- us2k10--------
    rs1843750831,2
    --47745823(+) TTCCTG/TTTCTC 1 -- us2k10--------
    rs122589591,2
    C--47745975(+) GCAGTA/GGCATG 1 -- us2k10--------
    rs618429161,2
    C--47746205(+) GCCACT/CGCACC 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs45845141,2
    C--47746235(-) CATCAG/CTCTCT 1 -- us2k13Minor allele frequency- C:0.00NA 6
    rs775145101,2
    C--47746286(+) GCCTGA/GCCCTC 1 -- us2k11Minor allele frequency- G:0.00NA 2

    HapMap Linkage Disequilibrium report for ANXA8L2 (47746920 - 47763041 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ANXA8L2 (see all 21):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv135e199CNV Deletion23128226
    nsv436102CNV Deletion17901297
    esv2736163CNV Deletion23290073
    nsv437116CNV Loss16327808
    nsv467059CNV Gain19166990
    dgv683n71CNV Gain21882294
    dgv689n71CNV Gain21882294
    nsv895336CNV Gain21882294
    dgv656n71CNV Gain21882294
    esv26219CNV Gain+Loss19812545

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ANXA8L2
    DNA2.0 Custom Variant and Variant Library Synthesis for ANXA8L2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for ANXA8L2:    
    About MalaCards
    acute promyelocytic leukemia

    1 disease from the University of Copenhagen DISEASES database for ANXA8L2:
    Adenosquamous carcinoma

    Find genes that share disorders with ANXA8L2           About GenesLikeMe

    4 Novoseek inferred disease relationships for ANXA8L2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia promyelocytic acute 73.7 1 8018923 (1)
    leukemia 30.9 2 8069182 (1), 8231235 (1)
    carcinoma 13.2 1 18223320 (1)
    tumors 0 1 16203777 (1)


    Export disorders for ANXA8L2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ANXA8L2 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with ANXA8L2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    4. Regulation of the expression of annexin VIII in acute promyelocytic leukemia. (PubMed id 8018923)1, 9 Sarkar A....Chang K.S. (Blood 1994)
    5. Differential tissue expression of Annexin VIII in human. (PubMed id 8045287)1, 9 Reutelingsperger C.P....Tiebosch A. (FEBS Lett. 1994)
    6. New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. (PubMed id 18223320)1, 9 Karanjawala Z.E....Hruban R.H. (Am. J. Surg. Pathol. 2008)
    7. TaqI polymorphisms at the annexin VIII locus (ANX8). (PubMed id 1364010)1, 9 Chambers J.A....Mulligan L.M. (Hum. Mol. Genet. 1992)
    8. The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma. (PubMed id 21800051)1 Fang Y....Shen X. (Mol. Cell. Biochem. 2012)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 244 HGNC: 23335 AceView: ANXA8.2 Ensembl:ENSG00000186807 euGenes: HUgn244
    ECgene: ANXA8L2 H-InvDB: ANXA8L2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ANXA8L2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ANXA8L2 gene:
    Search GeneIP for patents involving ANXA8L2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ANXA8L2  
     OriGene qPCR primer pairs and template standards for ANXA8L2   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ANXA8L2  
     OriGene qSTAR qPCR primer pairs in human, mouse for ANXA8L2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ANXA8L2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ANXA8L2   OriGene Custom Protein Services for ANXA8L2  

     
     
     Block miRNA regulation of human, mouse, rat ANXA8L2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ANXA8L2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANXA8L2 Predesigned siRNA for gene silencing in human, mouse, rat ANXA8L2
     QuantiFast Probe-based Assays in human, mouse, rat ANXA8L2 QuantiTect SYBR Green Assays in human, mouse, rat ANXA8L2
     Custom PCR Arrays for ANXA8L2 Search Chromatin IP Primers for ANXA8L2
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat ANXA8L2 Search GeneGlobe Interaction Network for ANXA8L2
     Regulatory tfbs in ANXA8L2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ANXA8L2 GenScript cDNA clones with any tag delivered in your preferred vector for ANXA8L2
     GenScript Custom Assay Services for ANXA8L2 GenScript Custom overexpressing Cell Line Services for ANXA8L2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ANXA8L2 (AXA82)
     Proteins for ANXA8L2
     Browse Sino Biological Cell Lysates
     cDNA Clones for ANXA8L2
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ANXA8L2 antibodies
     ANXA8L2 proteins
     Antibodies for ANXA8L2
     See all of Abcam's Antibodies, Kits and Proteins for ANXA8L2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for ANXA8L2
     Proteins for ANXA8L2
     Antibodies for ANXA8L2
     ELISAs for ANXA8L2
     CLIAs for ANXA8L2



     Browse ESI BIO Cell Lines and PureStem Progenitors for ANXA8L2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA8L2
     SwitchGear 3'UTR luciferase reporter plasmids for ANXA8L2
     SwitchGear Promoter luciferase reporter plasmids for ANXA8L2
     Search ThermoFisher Antibodies for ANXA8L2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANXA8L2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ANXA8L2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ANXA8L2
     LSBio Antibodies in human, mouse, rat for ANXA8L2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ANXA8L2
      Search eBioscience for proteins for ANXA8L2
      Search eBioscience for elisas for ANXA8L2
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ANXA8L2 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4