V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

ANXA7 Gene

protein-coding GIFtS: 59

GC10M074805

annexin A7
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: ANX7)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ANX7 ^², ³
Annexin-7 ^³
OTTHUMP00000019812 ^²
OTTHUMP00000019813 ^²
OTTHUMP00000042922 ^²
OTTHUMP00000042923 ^²
OTTHUMP00000042925 ^²
SNX ^², ³, ⁵
SYNEXIN ^²
Synexin ^³

Descriptions
Annexin VII ^², ³
annexin A7 ^²

External Ids
HGNC: 545¹
Entrez Gene: 310²
UniProtKB: P20073³
Ensembl: ENSG00000138279⁷

Search outside databases for aliases for ANXA7 gene

Previous GC identifers: GC10M073913 GC10M074238 GC10M075027 GC10M074479

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ANXA7:

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding

proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An

alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are

predicted to generate two protein isoforms differing in their N-terminal domain. The alternative

splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain,

heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the

use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of

approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a

conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating

hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII

is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel

activity, ion selectivity and membrane fusion. [provided by RefSeq]

UniProtKB/Swiss-Prot: ANXA7_HUMAN, P20073

Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in

exocytosis

Gene Wiki entry for ANXA7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ANXA7 gene

Entrez Gene cytogenetic band: 10q21.1-q21.2 Ensembl cytogenetic band: 10q22.2 HGNC cytogenetic band: 10q22.2

ANXA7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M074805: (about GC identifiers)

Start:	74,805,210 bp from pter
End:	74,843,817 bp from pter
Size:	38,608 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000010.9 NT_008583.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ANXA7_HUMAN, P20073 (See protein sequence)

Recommended Name: Annexin A7

Size: 488 amino acids; 52739 Da

Sequence caution: Sequence=CAI52483.1; Type=Erroneous gene model prediction;

Secondary accessions: Q5F2H3 Q5T0M6 Q5T0M7

Alternative splicing: 2 isoforms: P20073-1 P20073-2

REFSEQ proteins (2 alternative transcripts):

NP_001147.1 NP_004025.1

ENSEMBL proteins:

ENSP00000362010 ENSP00000362012 ENSP00000378317

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Annexin VII)
	Human Recombinant Proteins from Abnova (ANXA7)

OriGene Purified Recombinant Human Proteins (see all 2): ANXA7

5/7 Gene Ontology (GO) cellular component terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005625	soluble fraction	IEA	--
GO:0005626	insoluble fraction	IEA	--
GO:0005634	nucleus	IEA	--
GO:0005635	nuclear envelope	IEA	--
GO:0005829	cytosol	IEA	--

About this table

Antibodies for ANXA7:

	Invitrogen Antibodies for ANXA7
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibody Arrays and Antibodies for ANXA7
	R&D Systems Antibodies for ANXA7 (Annexin A7)
	Cell Signaling Technology (CST) Antibodies for ANXA7 (Annexin A7)
	Antibodies from Abcam (Annexin VII), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ANXA7)
	Novus Biologicals Antibodies for ANXA7

Assays for ANXA7:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P20073

ProtoNet protein and cluster: P20073

2 Blocks protein families:

IPB001464 Annexin

IPB002391 Annexin type IV signature

UniProtKB/Swiss-Prot: ANXA7_HUMAN, P20073

Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid

Similarity: Belongs to the annexin family

Similarity: Contains 4 annexin repeats

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ANXA7)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ANXA7)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001156

Applied Biosystems Silencer® siRNAs for ANXA7

Sigma-Aldrich siRNA for ANXA7

Sigma-Aldrich shRNA for ANXA7

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ANXA7
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001156
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001156
untagged cDNA clones in CMV expression vector (see all 3): NM_001156

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004034

UniProtKB/Swiss-Prot: ANXA7_HUMAN, P20073

Function: Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in

exocytosis

Genatlas biochemistry entry for ANXA7:

annexin A7,two forms,47kDa,51kDa,calcium and phospholipid binding protein,synexin,expressed in

adrenal medullary cells,skeletal muscle,brain,liver

13 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Anxa7):

	cellular	digestive/alimentary	endocrine/exocrine gland	growth/size
hematopoietic system	homeostasis/metabolism	immune system	lethality-prenatal/perinatal	life span-post-weaning/aging
nervous system	skeleton	tumorigenesis

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--
GO:0005515	protein binding	IEA	--
GO:0005544	calcium-dependent phospholipid binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ANXA7

5/19 Interacting proteins for ANXA7 (ENSP00000362010³) via UniProtKB, MINT, and/or STRING (see all 19 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SRI	ENSP00000265729³	STRING (score=.981)
SNX2	ENSP00000368831³	STRING (score=.92)
SNX4	ENSP00000251775³	STRING (score=.918)
VPS35	ENSP00000299138³	STRING (score=.915)
VPS26A	ENSP00000362480³	STRING (score=.913)

About this table

5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006874	cellular calcium ion homeostasis	IEA	--
GO:0007599	hemostasis	IEA	--
GO:0008283	cell proliferation	IEA	--
GO:0008360	regulation of cell shape	IEA	--
GO:0009651	response to salt stress	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ANXA7
4 Novoseek chemical compound relationships for ANXA7 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
phospholipid	57.72	3	8670145 (1), 9078249 (1), 16843057 (1)
calcium	34.12	20	9078249 (6), 2170654 (1), 1318099 (1), 2184163 (1) (see all 9)
lipid	8.00	6	9078249 (2), 17765009 (2), 11895795 (1), 2139437 (1)
arachidonic acid	5.90	3	9078249 (2), 17018618 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ANXA7)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ANXA7)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001156

Sigma-Aldrich siRNA for ANXA7

Sigma-Aldrich shRNA for ANXA7

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001156 NM_004034

REFSEQ mRNAs for ANXA7 gene (2 alternative transcripts):

NM_001156.3 NM_004034.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001156 NM_004034

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001156
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001156
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001156

Additional cDNA sequence:

AB062429.1 AK222552.1 AK295319.1 AK300086.1 AK301681.1 AK307772.1 AK309141.1 AK312447.1

AK313024.1 BC001322.1 BC002632.2 BT007187.1 CR407686.1 CR590056.1 CR593533.1 CR603295.1

CR611487.1 CR614618.1 CR616705.1 CR616728.1 CR617521.1 CR619341.1 CR623322.1 CR624692.1

J04543.1 M64272.1

24/26 DOTS entries (see all 26 ):

DT.100684618 DT.100684614 DT.100684624 DT.100684623 DT.100707250 DT.218353 DT.100038086 DT.100684616

DT.91679511 DT.95359651 DT.97826422 DT.121297658 DT.121297682 DT.92345023 DT.92448036 DT.100692557

DT.121297623 DT.121297637 DT.95359631 DT.100038087 DT.100684619 DT.100684620 DT.100684621 DT.121297643

24/480 AceView cDNA sequences (see all 480 ):

AU127783 BX397600 AL041680 BX395922 F08424 W39757 BX443500 AW955240

CR617521 BQ434142 BG777788 BF514426 AU280020 CR616728 AI335869 AL041399

CR593533 CF138760 CR603295 AU141133 BQ672791 BX457713 CR407686 BC002632

highest scoring ESTs for ANXA7:

J04543 AB062429 AU280020 BC002632 BF211651 BF245354 BG390703 BG489626 BI763576 BI908419

Unigene Cluster for ANXA7:

Annexin A7

Hs.631827 [show with all ESTs]

Unigene Representative Sequence: NM_004034

GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:

ENST00000372919 ENST00000372921 ENST00000394847

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ANXA7 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ANXA7

¹ / ² / ³

5 probe-sets matching ANXA7 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37670_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	J04543	1.00	1.00	1.00	1
209860_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	J04543	1.00	1.00	1.00	1
201366_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004034	0.60	1.00	0.82	1
209860_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
201366_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.631827
Expression variation in blood from EXPOLDB for ANXA7
UniProtKB/Swiss-Prot: ANXA7_HUMAN, P20073
Tissue specificity: Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more
abundant in liver, lung, kidney, spleen, fibroblasts and placenta

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ANXA7 gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ANXA7¹	--	annexin A7	91.85(n) 93.13(a)	479246 XM_536388.2 XP_536388.1
chimpanzee (Pan troglodytes)	ANXA7¹	--	annexin A7	99.79(n) 99.57(a)	737825 XM_001138374.1 XP_001138374.1
cow (Bos taurus)	ANXA7¹	--	annexin A7	91.86(n) 93.3(a)	533360 NM_001075991.1 NP_001069459.1
rat (Rattus norvegicus)	Anxa7¹	--	annexin A7	87.11(n) 92.44(a)	155423 NM_130416.1 NP_569100.1
mouse (Mus musculus)	Anxa7^{1, 5}	14 (2.50 cM)⁵	annexin A7^{1, 5}	87.26(n)¹ 92.44(a)¹	11750¹ NM_009674.2¹ NP_033804.1¹ AI265384⁵ AI316497⁵ (see all 28)

About this table Species with no ortholog for ANXA7

ENSEMBL Gene Tree for ANXA7

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ANXA7 gene

ANXA6² ANXA5² ANXA8L2² ANXA8L1² ANXA4² ANXA8²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/168 NCBI SNPs in ANXA7 are shown (see all 168 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 54)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs3812623^1,2	A,C,F,H	74843895(+)	`GGAACA/GCCCCC`	2	--	ng3¹ tfbs³		7		NA EU EA WA	560
	rs7921604^1,2	A,C,F,H	74843784(+)	`ACCCCA/GGCAGC`	2	--	ut5¹ ese³		7		EU EA WA NA	558
	rs6896^1,2	C,F,H,O	74805452(+)	`TAACAT/CACTAT`	2	--	ut3¹ ese³		17		NA EA MN EU WA	1694
	rs12570678^1,2	C,F,H	74845022(+)	`ACAGGG/TTATTT`	2	--	ng3¹		4		EU EA WA	412
	rs3750575^1,2	C,F,H	74808697(-)	`GGTCCG/AGATTG`	2	Q/R	mis¹ ese³		9		EA EU WA	1764
	rs12571847^1,2	C,F,H	74844926(+)	`GGATTT/AAAGCC`	2	--	ng3¹		4		EU EA WA	416
	rs12570685^1,2	C,F,H	74845081(+)	`CAATAG/TTCTAC`	2	--	ng3¹		4		EU EA WA	420
	rs1050586^1,2	C,H	74805320(-)	`GTGGCA/CCCTTT`	2	--	ut3¹		11		NA EA MN EU WA	1106
	rs14858^1,2	F,H	74805661(-)	`ACAATC/TAATGT`	2	--	ut3¹		8		NA EA MN EU WA	856
--	rs7893866^1,2	A	74843939(+)	`TCCCTC/GAGTCC`	2	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for ANXA7 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 186360

2 Novoseek disease relationships for ANXA7 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
cancer	0.00	4	17018618 (1), 18449914 (1), 17708571 (1), 14609169 (1)
tumors	0.00	8	14609169 (4), 17018618 (1), 18449914 (1), 18854424 (1) (see all 5)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/68 PubMed articles for ANXA7 gene (see all 68 ):

Divergent structure of the human synexin (annexin VII) gene and assignment to chromosome 10. (PubMed id 7515686)^{1, 2, 3, 4} Shirvan A.... Burns A.L. (1994)
Alternative splicing of human synexin mRNA in brain, cardiac, and skeletal muscle alters the unique N-terminal domain. (PubMed id 1825209)^{1, 3, 4} Magendzo K....Burns A.L. (1991)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Calcium channel activity of purified human synexin and structure of the human synexin gene. (PubMed id 2542947)^{3, 4} Burns A.L.... Pollard H.B. (1989)
Calcium-dependent binding of sorcin to the N-terminal domain of synexin (annexin VII). (PubMed id 9268363)^{1, 3} Brownawell A.M. and Creutz C.E. (1997)
Differential recognition of secretory vesicles by annexins. European Molecular Biology Organization Course "Advanced Techniques for Studying Secretion". (PubMed id 1533123)^{1, 3} Creutz C.E....Gomperts B. (1992)
Distinct effects of annexin A7 and p53 on arachidonate lipoxygenation in prostate cancer cells involve 5-lipoxygenase transcription. (PubMed id 17018618)^{1, 3} Torosyan Y....Srivastava M. (2006)
Expression and localisation of annexin VII (synexin) isoforms in differentiating myoblasts. (PubMed id 10672515)^{1, 3} Clemen C.S....Noegel A.A. (1999)
The significance of ANXA7 expression and its correlation with poor cellular differentiation and enhanced metastatic potential of gastric cancer. (PubMed id 18449914)^{1, 3} Hsu P.I....Hsiao M. (2008)
ANXA7 expression represents hormone-relevant tumor suppression in different cancers. (PubMed id 17708571)^{1, 3} Srivastava M....Bubendorf L. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 310	HGNC: 545	AceView: ANXA7	Ensembl:ENSG00000138279	euGenes: HUgn310
ECgene: ANXA7	H-InvDB: ANXA7

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for ANXA7	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ANXA7
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ANXA7:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ANXA7-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ANXA7		Antibodies for ANXA7
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ANXA7		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ANXA7)
	Antibodies (ANXA7)
	Chimera RNAi (ANXA7)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for ANXA7 (Annexin A7)

	Recombinant Proteins (Annexin VII)
	Antibodies (Annexin VII)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ANXA7

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ANXA7

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
ANXA7 Gene at Home site.
Version 2.41.1
server4.xennexinc.com

ANXA7 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for ANXA7

Summaries
for ANXA7

Genomic Location
for ANXA7

Proteins
for ANXA7

Protein Domains/
Families
for ANXA7

Gene Function
for ANXA7

Pathways & Interactions
for ANXA7

Drugs & Compounds
for ANXA7

Transcripts
for ANXA7

Expression
for ANXA7

Orthologs
for ANXA7

Paralogs
for ANXA7

SNPs/Variants
for ANXA7

Disorders & Mutations
for ANXA7

Medical News
for ANXA7

Publications
for ANXA7

Search for ANXA7

Genome Databases showing ANXA7

Other Databases showing ANXA7

Specialized Databases showing ANXA7

Licensable Technologies
for ANXA7

Services
for ANXA7

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ANXA7 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor ANXA7

Summariesfor ANXA7

Genomic Locationfor ANXA7

Proteinsfor ANXA7

Protein Domains/Familiesfor ANXA7

Gene Functionfor ANXA7

Pathways & Interactionsfor ANXA7

Drugs & Compoundsfor ANXA7

Transcriptsfor ANXA7

Expression for ANXA7

Orthologsfor ANXA7

Paralogsfor ANXA7

SNPs/Variantsfor ANXA7

Disorders & Mutationsfor ANXA7

Medical Newsfor ANXA7

Publicationsfor ANXA7

Search for ANXA7

Genome Databases showing ANXA7

Other Databases showing ANXA7

Specialized Databases showing ANXA7

Licensable Technologiesfor ANXA7

Servicesfor ANXA7

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ANXA7

Summaries
for ANXA7

Genomic Location
for ANXA7

Proteins
for ANXA7

Protein Domains/
Families
for ANXA7

Gene Function
for ANXA7

Pathways & Interactions
for ANXA7

Drugs & Compounds
for ANXA7

Transcripts
for ANXA7

Expression
for ANXA7

Orthologs
for ANXA7

Paralogs
for ANXA7

SNPs/Variants
for ANXA7

Disorders & Mutations
for ANXA7

Medical News
for ANXA7

Publications
for ANXA7

Licensable Technologies
for ANXA7

Services
for ANXA7