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ANXA3 Gene

protein-coding   GIFtS: 65
GCID: GC04P079472

Annexin A3


(Previous symbol: ANX3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Annexin A31 2     Annexin III (Lipocortin III)2
ANX31 2 3 5     Annexin III (Lipocortin III, 1,2-Cyclic-Inositol-Phosphate
Phosphodiesterase, Placental Anticoagulant Protein III, Calcimedin
35-Alpha)2
Inositol 1,2-Cyclic Phosphate 2-Phosphohydrolase2 3     annexin-32
Lipocortin III2 3     Calcimedin 35-Alpha2
Placental Anticoagulant Protein III2 3     Annexin-33
35-Alpha Calcimedin2 3     Annexin III3
PAP-III2 3     

External Ids:    HGNC: 5411   Entrez Gene: 3062   Ensembl: ENSG000001387727   OMIM: 1064905   UniProtKB: P124293   

Export aliases for ANXA3 gene to outside databases

Previous GC identifers: GC04P079403 GC04P079746 GC04P079865 GC04P079933 GC04P079925 GC04P079830 GC04P075219


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ANXA3 Gene:
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein
family play a role in the regulation of cellular growth and in signal transduction pathways. This protein
functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol
1-phosphate. This protein may also play a role in anti-coagulation. (provided by RefSeq, Jul 2008)

GeneCards Summary for ANXA3 Gene:
ANXA3 (annexin A3) is a protein-coding gene. Diseases associated with ANXA3 include headache, and cluster headache. GO annotations related to this gene include phospholipase A2 inhibitor activity and calcium ion binding. An important paralog of this gene is ANXA6.

UniProtKB/Swiss-Prot: ANXA3_HUMAN, P12429
Function: Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of
inositol 1,2-cyclic phosphate to form inositol 1-phosphate

Gene Wiki entry for ANXA3 (Annexin A3) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000004.12  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANXA3 gene promoter:
         Max1   AML1a   FOXD1   Lmo2   POU3F2 (N-Oct-5a)   POU3F2   SEF-1 (1)   TGIF   c-Myc   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANXA3 promoter sequence
   Search Chromatin IP Primers for ANXA3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANXA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.21   Ensembl cytogenetic band:  4q21.21   HGNC cytogenetic band: 4q21.21

ANXA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANXA3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P079472:  view genomic region     (about GC identifiers)

Start:
79,472,673 bp from pter      End:
79,531,605 bp from pter
Size:
58,933 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ANXA3_HUMAN, P12429 (See protein sequence)
Recommended Name: Annexin A3  
Size: 323 amino acids; 36375 Da
2 PDB 3D structures from and Proteopedia for ANXA3:
1AII (3D)        1AXN (3D)    
Secondary accessions: B2R9W6 Q6LET2

Explore the universe of human proteins at neXtProt for ANXA3: NX_P12429

Explore proteomics data for ANXA3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys210
  • Modification sites at PhosphoSitePlus

  • See ANXA3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005130.1  
    ENSEMBL proteins: 
     ENSP00000264908   ENSP00000423068   ENSP00000426591   ENSP00000421015   ENSP00000424584  
     ENSP00000421512   ENSP00000422281  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANXA: Annexins

    4 InterPro protein domains:
     IPR018502 Annexin_repeat
     IPR001464 Annexin
     IPR018252 Annexin_repeat_CS
     IPR002390 AnnexinIII

    Graphical View of Domain Structure for InterPro Entry P12429

    ProtoNet protein and cluster: P12429

    2 Blocks protein domains:
    IPB001464 Annexin
    IPB002390 Annexin type III signature


    UniProtKB/Swiss-Prot: ANXA3_HUMAN, P12429
    Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid
    Similarity: Belongs to the annexin family
    Similarity: Contains 4 annexin repeats


    ANXA3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANXA3_HUMAN, P12429
    Function: Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of
    inositol 1,2-cyclic phosphate to form inositol 1-phosphate

         Genatlas biochemistry entry for ANXA3:
    annexin A3,calelectrin 32.5

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004859phospholipase inhibitor activity ----
    GO:0005509calcium ion binding IEA--
    GO:0005544calcium-dependent phospholipid binding IDA2138016
    GO:0019834phospholipase A2 inhibitor activity IEA--
         
    ANXA3 for ontologies           About GeneDecksing


    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    cytoskeleton2
    nucleus2
    endosome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA7526843
    GO:0016020membrane IDA17205602
    GO:0030670phagocytic vesicle membrane IDA7526843
    GO:0042581specific granule IDA7526843

    ANXA3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ANXA3 About    
    See pathways by source

    SuperPathContained pathways About
    1Prostaglandin Synthesis and Regulation
    Prostaglandin Synthesis and Regulation


    1 BioSystems Pathway for ANXA3
        Prostaglandin Synthesis and Regulation



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANXA3
    Interactions:

        Search GeneGlobe Interaction Network for ANXA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for ANXA3 (P124292, 3 ENSP000002649084) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TP53P046372, 3MINT-63460 I2D: score=5 
    UBR1Q8IWV72, 3MINT-63462 I2D: score=5 
    UNC119Q134322, 3MINT-63461 I2D: score=5 
    EMG1Q929792, 3MINT-65072 I2D: score=4 
    IGSF21Q96ID52, 3MINT-63463 I2D: score=4 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006909phagocytosis IDA9497492
    GO:0010595positive regulation of endothelial cell migration IDA16236264
    GO:0042742defense response to bacterium IDA9497492
    GO:0043312neutrophil degranulation IDA9550422
    GO:0045766positive regulation of angiogenesis IDA16236264

    ANXA3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANXA3

    6 HMDB Compounds for ANXA3    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    Glycerol1,2,3-Trihydroxypropane (see all 22)56-81-5--
    Inositol cyclic phosphate1D-myo-Inositol 1,2-cyclic phosphate (see all 7)43119-57-9--
    Inositol phosphate1D-myo-Inositol 1-monophosphate (see all 4)15421-51-9--
    Myo-inositol 1-phosphate1-(dihydrogen phosphate) DL-myo-Inositol (see all 8)573-35-3--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    1 DrugBank Compound for ANXA3    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Ethanolamine-- 141-43-5target----

    9 Novoseek inferred chemical compound relationships for ANXA3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    inositol 1,2-cyclic phosphate 81.8 8 2159184 (3), 1830024 (1)
    isocitrate 51.9 3 17181965 (1), 17269733 (1), 15292099 (1)
    phosphatidylethanolamine 36.5 2 9111038 (1), 2138016 (1)
    phospholipid 33.8 3 9111038 (1), 1839615 (1)
    calcium 32.4 9 8262618 (1), 9191044 (1), 19388055 (1), 2159184 (1) (see all 6)
    cisplatin 25.9 1 20103635 (1)
    superoxide 11.3 2 17070997 (1), 16391823 (1)
    phosphatidylcholine 9.64 1 2138016 (1)
    phosphatidylinositol 6.2 1 2159184 (1)



    ANXA3 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ANXA3 gene: 
    NM_005139.2  

    Unigene Cluster for ANXA3:

    Annexin A3
    Hs.480042  [show with all ESTs]
    Unigene Representative Sequence: AB209868
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000264908(uc003hld.3) ENST00000512884 ENST00000512542 ENST00000503570
    ENST00000510502 ENST00000512373 ENST00000514171 ENST00000508214 ENST00000505805
    ENST00000503776
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    Additional mRNA sequence: 

    AB209868.1 AK313945.1 BC000871.1 CR407648.1 M20560.1 M63310.1 

    15 DOTS entries:

    DT.315349  DT.95108739  DT.91883783  DT.100814762  DT.95360236  DT.97811374  DT.101960740  DT.91769630 
    DT.95278421  DT.100814761  DT.100814764  DT.102824871  DT.121253441  DT.95075222  DT.95284243 

    Selected AceView cDNA sequences (see all 204):

    BM763243 CR600226 CR611294 CR621887 BM847811 CD678072 BM973148 CR601701 
    BM922279 BC000871 CD678071 BM840625 CB113457 BM755286 CB267704 BU674495 
    M63310 BM763078 AW770322 AA167096 AL597591 BU681304 CR622182 CR590148 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ANXA3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b
    SP1:                    -     -           -                       -                             -                                 
    SP2:                    -     -                                   -                             -                                 
    SP3:                    -                 -                                                                                       
    SP4:                                      -                       -                                                               
    SP5:                    -     -           -                                                                                       


    ECgene alternative splicing isoforms for ANXA3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANXA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGGCGCGG
    ANXA3 Expression
    About this image


    ANXA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 16) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Primitive Heart Tube Cells Primitive Heart Tube
             Heart Tube
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Duct Cells Pancreatic Ducts
             Islets of Langerhans
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Trophoblast (Extraembryonic Tissues)    fully expand to see all 2 entries
             Trophoblast Cells Trophoblast
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
    ANXA3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANXA3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.480042
        Custom PCR Arrays for ANXA3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ANXA3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Anxa31 , 5 annexin A31, 5 84.73(n)1
    89.78(a)1
      5 (47.29 cM)5
    117451  NM_013470.21  NP_038498.21 
     967933855 
    lizard
    (Anolis carolinensis)
    Reptilia ANXA36
    annexin A3
    78(a)
    1 ↔ 1
    5(145523776-145556457)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.38632 Xenopus laevis transcribed sequence with moderate similarity more 76.36(n)    CF286235.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb60b032 wufb60b03 67.28(n)   322404  BQ259076.1 
    worm
    (Caenorhabditis elegans)
    Secernentea nex-23 Annexin 44(a)
    (best of 2)
      III(10397630-10399688)   --


    ENSEMBL Gene Tree for ANXA3 (if available)
    TreeFam Gene Tree for ANXA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANXA3 gene
    ANXA62  ANXA52  ANXA12  ANXA92  ANXA22  ANXA72  ANXA82  ANXA112  
    ANXA8L22  ANXA102  ANXA8L12  ANXA42  ANXA132  
    15 SIMAP similar genes for ANXA3 using alignment to 6 protein entries:     ANXA3_HUMAN (see all proteins):
    ANXA4    ANXA6    ANXA8L2    ANXA7    DKFZp686H02120    ANXA13
    ANXA11    ANXA10    ANXA5    ANXA8    ANXA2P2    ANXA8L1
    ANXA2    ANXA1    ANXA9

    ANXA3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANXA3 (see all 1247)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1471364931,2
    C--79470774(+) GCCATA/GGCATG 1 -- us2k10--------
    rs1486237911,2
    --79470856(+) TTGTTA/GAAGTT 1 -- us2k10--------
    rs1818083871,2
    C--79470864(+) GTTACC/TATCAG 1 -- us2k10--------
    rs1855058811,2
    --79470926(+) ACATGA/TAAAAC 1 -- us2k10--------
    rs1904297291,2
    --79470961(+) GGCTAC/TAAATC 1 -- us2k10--------
    rs1808532881,2
    --79470974(+) GCCCTA/GTGACT 1 -- us2k10--------
    rs728733351,2
    C,F--79471085(+) TTGGTA/GAGCAT 1 -- us2k12Minor allele frequency- G:0.12WA 120
    rs1411517431,2
    --79471106(+) ACGTAC/TGTCAA 1 -- us2k10--------
    rs743754261,2
    F--79471161(+) CCCATT/ATCATG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1855031661,2
    C--79471335(+) CCAGGA/GCACTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ANXA3 (79472673 - 79531605 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ANXA3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv271571CNV Insertion20981092
    esv273006CNV Insertion20981092
    nsv7363OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 106490    OMIM disorders: --

    Selected diseases for ANXA3 (see all 30):    
    About MalaCards
    headache    cluster headache    gallbladder cancer    vaginitis
    nephrotic syndrome    ovarian cancer    lung adenocarcinoma    tuberculosis
    thyroid cancer    choroiditis    infertility    psoriasis
    prostate cancer    thyroiditis    myocardial infarction    prostatitis
    rheumatoid arthritis    renal cell carcinoma    arthritis    adenocarcinoma


    ANXA3 for disorders           About GeneDecksing

    5 Novoseek inferred disease relationships for ANXA3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ovarian cancer 23.9 4 20103635 (4)
    prostate cancer 22.8 6 18222597 (2), 19012935 (1), 20218320 (1), 18222603 (1) (see all 5)
    cancer 11 8 19012935 (2), 17205602 (2), 20103635 (1), 20167856 (1)
    shock 7.38 3 18347185 (1), 17593366 (1), 15292099 (1)
    tuberculosis 0 1 9497492 (1)

    Genetic Association Database (GAD): ANXA3
    Human Genome Epidemiology (HuGE) Navigator: ANXA3 (1 document)

    Export disorders for ANXA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANXA3 gene, integrated from 10 sources (see all 96):
    (articles sorted by number of sources associating them with ANXA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chromosomal localization of the human annexin III (ANX3) gene. (PubMed id 1830024)1, 2, 3, 9 Tait J.F....Disteche C.M. (Genomics 1991)
    2. Identity of inositol 1,2-cyclic phosphate 2-phosphohydrolase with lipocortin III. (PubMed id 2159184)1, 2, 9 Ross T.S.... Majerus P.W. (Science 1990)
    3. The high-resolution crystal structure of human annexin III shows subtle differences with annexin V. (PubMed id 8639653)1, 2, 9 Favier-Perron B.... Russo-Marie F. (Biochemistry 1996)
    4. Structure and polymorphisms of the human annexin III (ANX3) gene. (PubMed id 8276419)1, 2, 9 Tait J.F.... Cookson B.T. (Genomics 1993)
    5. Purification and characterization of an abundant cytosolic protein from human neutrophils that promotes Ca2(+)-dependent aggregation of isolated specific granules. (PubMed id 2138632)1, 2, 9 Ernst J.D.... Jaye D. (J. Clin. Invest. 1990)
    6. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. (PubMed id 22446963)1, 4 Okada Y....Yamamoto K. (Nat. Genet. 2012)
    7. Association of common variants in TNFRSF13B, TNFSF13, and ANXA3 with serum levels of non-albumin protein and immunoglobulin isotypes in Japanese. (PubMed id 22558069)1, 4 Osman W....Nakamura Y. (PLoS ONE 2012)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (Nat. Biotechnol. 2003)
    10. Characterization of single-nucleotide polymorphisms in coding regions of human genes. (PubMed id 10391209)1, 2 Cargill M....Lander E.S. (Nat. Genet. 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 306 HGNC: 541 AceView: ANXA3 Ensembl:ENSG00000138772 euGenes: HUgn306
    ECgene: ANXA3 H-InvDB: ANXA3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ANXA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ANXA3 gene:
    Search GeneIP for patents involving ANXA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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