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Aliases for ANXA2R Gene

Aliases for ANXA2R Gene

  • Annexin A2 Receptor 2 3
  • C5orf39 3 4 6
  • AXIIR 3 4 6
  • AX2R 3 4 6
  • Annexin II Receptor 3 4
  • Chromosome 5 Open Reading Frame 39 2
  • Annexin-2 Receptor 3

External Ids for ANXA2R Gene

Previous HGNC Symbols for ANXA2R Gene

  • C5orf39

Summaries for ANXA2R Gene

GeneCards Summary for ANXA2R Gene

ANXA2R (Annexin A2 Receptor) is a Protein Coding gene.

UniProtKB/Swiss-Prot for ANXA2R Gene

  • May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANXA2R Gene

Genomics for ANXA2R Gene

Genomic Location for ANXA2R Gene

43,039,080 bp from pter
43,043,170 bp from pter
4,091 bases
Minus strand

Genomic View for ANXA2R Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANXA2R Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANXA2R Gene

No data available for Regulatory Elements for ANXA2R Gene

Proteins for ANXA2R Gene

  • Protein details for ANXA2R Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Annexin-2 receptor
    Protein Accession:
    Secondary Accessions:
    • Q8NHX5

    Protein attributes for ANXA2R Gene

    193 amino acids
    Molecular mass:
    21682 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANXA2R Gene

Proteomics data for ANXA2R Gene at MOPED

Post-translational modifications for ANXA2R Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANXA2R Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ANXA2R Gene

Domains for ANXA2R Gene

Protein Domains for ANXA2R Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANXA2R: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ANXA2R Gene

Function for ANXA2R Gene

Molecular function for ANXA2R Gene

UniProtKB/Swiss-Prot Function:
May act as a receptor for annexin II on marrow stromal cells to induce osteoclast formation

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANXA2R

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANXA2R Gene

Localization for ANXA2R Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANXA2R Gene

Pathways for ANXA2R Gene

SuperPathways for ANXA2R Gene

No Data Available

Interacting Proteins for ANXA2R Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000315915 for ANXA2R Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for ANXA2R Gene


No data available for Pathways by source for ANXA2R Gene

Transcripts for ANXA2R Gene

mRNA/cDNA for ANXA2R Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(43) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANXA2R Gene

Annexin A2 receptor:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANXA2R

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANXA2R Gene

No ASD Table

Relevant External Links for ANXA2R Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANXA2R Gene

mRNA expression in normal human tissues for ANXA2R Gene

mRNA differential expression in normal tissues according to GTEx for ANXA2R Gene

This gene is overexpressed in Whole Blood (7.7) and Spleen (5.4).

SOURCE GeneReport for Unigene cluster for ANXA2R Gene Hs.529385

mRNA Expression by UniProt/SwissProt for ANXA2R Gene

Tissue specificity: Widely expressed. Highly expressed in lymphocytes. Expressed in both resting CD4(+) and CD8(+) T-cells.
genes like me logo Genes that share expressions with ANXA2R: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Expression partners for ANXA2R Gene

Orthologs for ANXA2R Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ANXA2R Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ANXA2R 35
  • 99.48 (n)
  • 98.96 (a)
  • 99 (a)
Species with no ortholog for ANXA2R:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANXA2R Gene

Gene Tree for ANXA2R (if available)
Gene Tree for ANXA2R (if available)

Paralogs for ANXA2R Gene Pseudogenes for ANXA2R Gene

genes like me logo Genes that share paralogs with ANXA2R: view

No data available for Paralogs for ANXA2R Gene

Variants for ANXA2R Gene

Sequence variations from dbSNP and Humsavar for ANXA2R Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
VAR_033349 -
VAR_033348 -

Relevant External Links for ANXA2R Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANXA2R Gene

Disorders for ANXA2R Gene

No disorders were found for ANXA2R Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ANXA2R Gene

Publications for ANXA2R Gene

  1. Cloning and characterization of the annexin II receptor on human marrow stromal cells. (PMID: 16895901) Lu G. … Roodman G.D. (J. Biol. Chem. 2006) 2 3 4 23
  2. Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer. (PMID: 18636554) Shiozawa Y. … Taichman R.S. (J. Cell. Biochem. 2008) 2 3 23
  3. Annexin II increases osteoclast formation by stimulating the proliferation of osteoclast precursors in human marrow cultures. (PMID: 10359570) Menaa C. … Roodman G.D. (J. Clin. Invest. 1999) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3

Products for ANXA2R Gene

Sources for ANXA2R Gene

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