Aliases for ANXA2 Gene
External Ids for ANXA2 Gene
Previous Symbols for ANXA2 Gene
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ANXA2 Gene
ANXA2 (Annexin A2) is a Protein Coding gene. Among its related pathways are Tyrosine Kinases / Adaptors and Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and cytoskeletal protein binding. An important paralog of this gene is ANXA9.
UniProtKB/Swiss-Prot for ANXA2 Gene
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response