Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANXA13 Gene

protein-coding   GIFtS: 60
GCID: GC08M124762

Annexin A13


(Previous symbol: ANX13)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Annexin A131 2     Intestine-Specific Annexin2 3
ANX131 2 3 5     Annexin, Intestine-Specific2
ISA2 3 5     annexin-132
Annexin XIII2 3     Annexin-133

External Ids:    HGNC: 5361   Entrez Gene: 3122   Ensembl: ENSG000001045377   OMIM: 6025735   UniProtKB: P272163   

Export aliases for ANXA13 gene to outside databases

Previous GC identifers: GC08M123834 GC08M124750 GC08M124361 GC08M124649 GC08M120019


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANXA13 Gene:
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein
family play a role in the regulation of cellular growth and in signal transduction pathways. The specific
function of this gene has not yet been determined; however, it is associated with the plasma membrane of
undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced
transcript variants encoding different isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for ANXA13 Gene: 
ANXA13 (annexin A13) is a protein-coding gene. Diseases associated with ANXA13 include squamous cell papilloma, and patellofemoral pain syndrome. GO annotations related to this gene include calcium-dependent phospholipid binding and calcium ion binding. An important paralog of this gene is ANXA3.

Gene Wiki entry for ANXA13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANXA13 gene promoter:
         STAT5B   LHX3b/Lhx3b   p53   Nkx2-5   GATA-2   MEF-2A   LHX3a/Lhx3a   aMEF-2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANXA13 promoter sequence
   Search SABiosciences Chromatin IP Primers for ANXA13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANXA13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.13   Ensembl cytogenetic band:  8q24.13   HGNC cytogenetic band: 8q24.13

ANXA13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANXA13 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M124762:  view genomic region     (about GC identifiers)

Start:
124,693,034 bp from pter      End:
124,749,647 bp from pter
Size:
56,614 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANX13_HUMAN, P27216 (See protein sequence)
Recommended Name: Annexin A13  
Size: 316 amino acids; 35415 Da
Subcellular location: Cell membrane. Note=Associated with the plasma membrane of undifferentiated, proliferating
crypt epithelial cells as well as differentiated villus enterocytes
Secondary accessions: Q9BQR5
Alternative splicing: 2 isoforms:  P27216-1   P27216-2   

Explore the universe of human proteins at neXtProt for ANXA13: NX_P27216

Explore proteomics data for ANXA13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P27216

  • ANXA13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANXA13 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001003954.1  NP_004297.2  

    ENSEMBL proteins: 
     ENSP00000262219   ENSP00000390809   ENSP00000429358  

    Human Recombinant Protein Products for ANXA13: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ANXA13
    OriGene Protein Over-expression Lysate for ANXA13
    OriGene MassSpec for ANXA13 
    OriGene Custom Protein Services for ANXA13
    GenScript Custom Purified and Recombinant Proteins Services for ANXA13
    Novus Biologicals ANXA13 Proteins
    Novus Biologicals ANXA13 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for ANXA13
    Cloud-Clone Corp. Proteins for ANXA13 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane NAS1530946

    ANXA13 for ontologies           About GeneDecksing



    ANXA13 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for ANXA13 (Annexin A13)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ANXA13
    GenScript Custom Superior Antibodies Services for ANXA13
    Novus Biologicals ANXA13 Antibodies
    Abcam antibodies for ANXA13
    Cloud-Clone Corp. Antibodies for ANXA13 
    ThermoFisher Antibody for ANXA13
    LSBio Antibodies in human, mouse, rat for ANXA13 

    Assay Products for ANXA13: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ANXA13
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ANXA13
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ANXA13 
    Cloud-Clone Corp. CLIAs for ANXA13


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANXA: Annexins

    4 InterPro protein domains:
     IPR001464 Annexin
     IPR018252 Annexin_repeat_CS
     IPR009166 AnnexinXIII
     IPR018502 Annexin_repeat

    Graphical View of Domain Structure for InterPro Entry P27216

    ProtoNet protein and cluster: P27216

    2 Blocks protein domains:
    IPB001464 Annexin
    IPB002392 Annexin type V signature


    UniProtKB/Swiss-Prot: ANX13_HUMAN, P27216
    Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid
    Similarity: Belongs to the annexin family
    Similarity: Contains 4 annexin repeats


    ANXA13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for ANXA13:
    annexin A13,calcium and phospholipid binding protein

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005544calcium-dependent phospholipid binding NAS--
         
    ANXA13 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANXA13 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANXA13

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANXA13 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ANXA13 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANXA13
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ANXA13
    SwitchGear 3'UTR luciferase reporter plasmidANXA13 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANXA13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANXA13

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ANXA13
    Sirion Biotech Customized adenovirus for overexpression of ANXA13

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ANXA13 (see all 11)
    OriGene ORF clones in mouse, rat for ANXA13
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ANXA13 (NM_004306)
    Sino Biological Human cDNA Clone for ANXA13
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANXA13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANXA13
    Sirion Biotech Customized lentivirus for stable overexpression of ANXA13 
                         Customized lentivirus expression plasmids for stable overexpression of ANXA13 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ANXA13
    Search LifeMap BioReagents cell lines for ANXA13
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA13


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANXA13

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for ANXA13 (P272163 ENSP000002622194) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NMT1P304193, ENSP000002589604I2D: score=1 STRING: ENSP00000258960
    KIFC3Q9BVG83, ENSP000003689764I2D: score=1 STRING: ENSP00000368976
    NEDD4P469343, ENSP000003455304I2D: score=1 STRING: ENSP00000345530
    ACTA1P681333I2D: score=1 
    ACTG1P632613I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030154cell differentiation NAS1530946

    ANXA13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANXA13 (ANX13)

    1 HMDB Compound for ANXA13    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about ANXA13 / ANX13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANXA13 gene (2 alternative transcripts): 
    NM_001003954.1  NM_004306.2  

    Unigene Cluster for ANXA13:

    Annexin A13
    Hs.181107  [show with all ESTs]
    Unigene Representative Sequence: NM_001003954
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262219(uc003yqt.3) ENST00000419625(uc003yqu.3) ENST00000520519
    ENST00000523822 ENST00000520591 ENST00000519045
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANXA13
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ANXA13
    SwitchGear 3'UTR luciferase reporter plasmidANXA13 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANXA13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANXA13
    Clone
    Products:
         
    OriGene clones in human, mouse for ANXA13 (see all 11)
    OriGene ORF clones in mouse, rat for ANXA13
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ANXA13 (NM_004306)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANXA13
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANXA13
    Sirion Biotech Customized lentivirus for stable overexpression of ANXA13 
                         Customized lentivirus expression plasmids for stable overexpression of ANXA13 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ANXA13
    OriGene qSTAR qPCR primer pairs in human, mouse for ANXA13
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANXA13
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANXA13
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANXA13

    Additional mRNA sequence: 

    AJ306450.1 AK223374.1 AK290281.1 BC125158.1 CR541838.1 Z11502.1 

    3 DOTS entries:

    DT.453956  DT.91732113  DT.120638905 

    24/27 AceView cDNA sequences (see all 27):

    NM_004306 BM824630 NM_001003954 AI984289 BX280061 AK057781 BG542398 AJ306450 
    BG470198 T28629 BM792420 BG747425 Z11502 CR541838 BG248802 BP370194 
    AW295277 BG385819 AI927400 AI678696 BE293184 BG823061 BG385716 AW296908 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ANXA13    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                    -     -                                                                     
    SP2:              -     -     -                                                                     
    SP3:                          -                                                                     
    SP4:                                                                                                


    ECgene alternative splicing isoforms for ANXA13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANXA13 expression in normal human tissues (normalized intensities)      ANXA13 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAACTGGAT
    ANXA13 Expression
    About this image


    ANXA13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/8 selected tissues (see all 8) fully expand
     
     Kidney (Urinary System)    fully expand to see all 3 entries
             Presumptive Podocytes Podocyte Layer
             kidney ; cells in tubules   
             visceral organ/metanephros/calyx   
     
     Intestine (Gastrointestinal Tract)    fully expand to see all 3 entries
             small intestine ; glandular cells   
             small intestine   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   
     
     Pancreas (Endocrine System)    fully expand to see all 2 entries
             Duct Cells Pancreatic Ducts
             pancreas ; exocrine glandular cells   
     
     Liver (Hepatobiliary System)    fully expand to see all 2 entries
             Hepatocytes Liver Lobule
             liver ; bile duct cells   

    See ANXA13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANXA13

    SOURCE GeneReport for Unigene cluster: Hs.181107

    UniProtKB/Swiss-Prot: ANX13_HUMAN, P27216
    Tissue specificity: Gut specific

        SABiosciences Custom PCR Arrays for ANXA13
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ANXA13
    OriGene qSTAR qPCR primer pairs in human, mouse for ANXA13
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANXA13
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANXA13
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANXA13
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ANXA13 gene from 9/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Anxa131 , 5 annexin A131, 5 85.28(n)1
    86.69(a)1
      15 (24.66 cM)5
    697871  NM_027211.21  NP_081487.11 
     583418745 
    chicken
    (Gallus gallus)
    Aves ANXA131 annexin A13 71.27(n)
    72.37(a)
      420342  NM_001199501.1  NP_001186430.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANXA136
    --
    --
    70(a)
    69(a)
    1 ↔ many
    1 ↔ many
    4(6671243-6682567)
    4(6617669-6625707)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.251152 Xenopus laevis transcribed sequence with weak similarity more 75.58(n)    CB205973.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.165042 Transcribed sequence with weak similarity to protein more 77.77(n)    CK028447.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta AnnIX3 actin binding 50(a)
    (best of 3)
      93B10   --
    worm
    (Caenorhabditis elegans)
    Secernentea nex-23
    nex-11
    Annexin3
    Protein NEX-11
    46(a)
    (best of 2)3
    49.06(n)1
    42.52(a)1
      III(10397630-10399688)3
    1757141  NM_065708.51  NP_498109.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ANN51 annexin D5 49.05(n)
    37.04(a)
      843137  NM_105479.1  NP_564920.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g03949001 hypothetical protein 48.32(n)
    40.27(a)
      4346972  NM_001069631.1  NP_001063096.1 


    ENSEMBL Gene Tree for ANXA13 (if available)
    TreeFam Gene Tree for ANXA13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANXA13 gene
    ANXA32  ANXA62  ANXA52  ANXA12  ANXA92  ANXA22  ANXA72  ANXA82  
    ANXA112  ANXA8L22  ANXA102  ANXA8L12  ANXA42  
    15 SIMAP similar genes for ANXA13 using alignment to 3 protein entries:     ANX13_HUMAN (see all proteins):
    ANXA7    DKFZp686H02120    ANXA8L2    ANXA4    ANXA3    ANXA6
    ANXA2    ANXA11    ANXA1    ANXA2P2    ANXA5    ANXA8L1
    ANXA10    ANXA9    ANXA8

    ANXA13 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1299 SNPs in ANXA13 are shown (see all 1299)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2008307191,2
    Cuntested1124724923(+) CCATTC/TCTTTG 4 E G mis11Minor allele frequency- T:0.00EU 1323
    rs1844886041,2
    C--124692611(+) CAATGA/GATGAC 2 -- ds50010--------
    rs1902221241,2
    --124692621(+) CAACTA/GTGATT 2 -- ds50010--------
    rs1394499581,2
    --124692628(+) GATTAC/TTGGGC 2 -- ds50010--------
    rs78329601,2
    C,F,H--124692711(+) ACACAG/AAATCT 2 -- ds500111Minor allele frequency- A:0.03NS EA NA WA 1308
    rs1498657491,2
    --124692730(+) GGAACA/CAATTC 2 -- ds50010--------
    rs1824462311,2
    --124692809(+) AGAGGA/GAAGAC 2 -- ds50010--------
    rs100890311,2
    C,F,H--124692832(+) AATGTC/ATAGAG 2 -- ds50015Minor allele frequency- A:0.01NS EA CSA 416
    rs1866333191,2
    --124692893(+) TACAGC/TTTACA 2 -- ds50010--------
    rs1904058331,2
    C--124692951(+) TAAAAA/GATGTA 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for ANXA13 (124693034 - 124749647 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ANXA13:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv6373CNV Loss18451855
    nsv831451CNV Gain+Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ANXA13
    DNA2.0 Custom Variant and Variant Library Synthesis for ANXA13

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602573    OMIM disorders: --

    6 diseases for ANXA13:    About MalaCards
    squamous cell papilloma    patellofemoral pain syndrome    spondylosis    paine syndrome
    papilloma    endotheliitis


    ANXA13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ANXA13

    Export disorders for ANXA13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANXA13 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with ANXA13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins. (PubMed id 11961095)1, 2, 9 Iglesias J.M....Fernandez M.-P. (2002)
    2. A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexin. (PubMed id 1530946)1, 2, 9 Wice B.M. and Gordon J.I. (1992)
    3. Genomic locations of ANX11 and ANX13 and the evolutionary genetics of human annexins. (PubMed id 9503022)1, 3, 9 Morgan R.O....Fernandez M.P. (1998)
    4. A genome-wide search for loci interacting with known p rostate cancer risk-associated genetic variants. (PubMed id 22219177)1, 4 Tao S....Sun J. (2012)
    5. Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb. (PubMed id 10871286)1, 9 Plant P.J....Rotin D. (2000)
    6. Genome-wide association study of theta band event-rel ated oscillations identifies serotonin receptor gene HTR7 influencing risk of a lcohol dependence. (PubMed id 21184583)1 Zlojutro M....Almasy L. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Identification of annexin A13 as a regulator of chemo therapy resistance using random homozygous gene perturbation. (PubMed id 20701074)1 Reiske H....Kinch M.S. (2010)
    9. Genome-wide association study of pancreatic cancer in Japanese population. (PubMed id 20686608)4 Low S.K....Sakamoto H. (2010)
    10. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PubMed id 20235792)4 Uhl G.R....Munafo M.R. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 312 HGNC: 536 AceView: ANXA13 Ensembl:ENSG00000104537 euGenes: HUgn312
    ECgene: ANXA13 H-InvDB: ANXA13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANXA13 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ANXA13 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANXA13 gene:
    Search GeneIP for patents involving ANXA13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for ANXA13 (Annexin A13)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ANXA13  
     OriGene qPCR primer pairs and template standards for ANXA13   OriGene Protein Over-expression Lysate for ANXA13  
     OriGene MassSpec something-or-other for ANXA13   OriGene clones in human, mouse for ANXA13  
     OriGene qSTAR qPCR primer pairs in human, mouse for ANXA13   OriGene Purified Protein for ANXA13  
     OriGene ORF clones in mouse, rat for ANXA13   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ANXA13   OriGene Custom Protein Services for ANXA13  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANXA13
     QIAGEN SeqTarget long-range PCR primers for resequencing ANXA13
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANXA13
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANXA13
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANXA13
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANXA13
     GenScript Custom Purified and Recombinant Proteins Services for ANXA13 GenScript cDNA clones with any tag delivered in your preferred vector for ANXA13
     GenScript Custom Assay Services for ANXA13 GenScript Custom Superior Antibodies Services for ANXA13
     GenScript Custom overexpressing Cell Line Services for ANXA13 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ANXA13 promoter
     Search Chromatin IP Primers for ANXA13
     RT2 qPCR Primer Assay in human, mouse, rat ANXA13
     Search GNC Networks for ANXA13
     SABiosciences Custom PCR Arrays for ANXA13
     Search Tocris compounds for ANXA13 (ANX13)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for ANXA13
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ANXA13 antibodies
     ANXA13 proteins
     ANXA13 lysates
     Antibodies for ANXA13
     See all of Abcam's Antibodies, Kits and Proteins for ANXA13
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for ANXA13




     Proteins for ANXA13
     Antibodies for ANXA13
     ELISAs for ANXA13
     CLIAs for ANXA13
     Search LifeMap BioReagents cell lines for ANXA13
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA13
     SwitchGear 3'UTR luciferase reporter plasmids for ANXA13
     SwitchGear Promoter luciferase reporter plasmids for ANXA13
     ThermoFisher Antibody for ANXA13
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANXA13
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ANXA13
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANXA13
    Customized:
     lentivirus for stable overexpression of ANXA13
     lentivirus expression plasmids for stable overexpression of ANXA13
     adenovirus for overexpression of ANXA13
     LSBio Antibodies in human, mouse, rat for ANXA13
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ANXA13 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4