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ANXA13 Gene

protein-coding   GIFtS: 59
GCID: GC08M124693

Annexin A13


(Previous symbol: ANX13)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Annexin A131 2     Intestine-Specific Annexin2 3
ANX131 2 3 5     Annexin, Intestine-Specific2
ISA2 3 5     annexin-132
Annexin XIII2 3     Annexin-133

External Ids:    HGNC: 5361   Entrez Gene: 3122   Ensembl: ENSG000001045377   OMIM: 6025735   UniProtKB: P272163   

Export aliases for ANXA13 gene to outside databases

Previous GC identifers: GC08M123834 GC08M124750 GC08M124361 GC08M124649 GC08M124762 GC08M120019


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ANXA13 Gene:
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein
family play a role in the regulation of cellular growth and in signal transduction pathways. The specific
function of this gene has not yet been determined; however, it is associated with the plasma membrane of
undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced
transcript variants encoding different isoforms have been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for ANXA13 Gene:
ANXA13 (annexin A13) is a protein-coding gene. GO annotations related to this gene include calcium-dependent phospholipid binding and calcium ion binding. An important paralog of this gene is ANXA3.

Gene Wiki entry for ANXA13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NC_018919.2  NT_008046.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANXA13 gene promoter:
         STAT5B   LHX3b/Lhx3b   p53   Nkx2-5   GATA-2   MEF-2A   LHX3a/Lhx3a   aMEF-2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANXA13 promoter sequence
   Search Chromatin IP Primers for ANXA13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANXA13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.13   Ensembl cytogenetic band:  8q24.13   HGNC cytogenetic band: 8q24.13

ANXA13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANXA13 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M124693:  view genomic region     (about GC identifiers)

Start:
124,693,034 bp from pter      End:
124,749,647 bp from pter
Size:
56,614 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ANX13_HUMAN, P27216 (See protein sequence)
Recommended Name: Annexin A13  
Size: 316 amino acids; 35415 Da
Secondary accessions: Q9BQR5
Alternative splicing: 2 isoforms:  P27216-1   P27216-2   

Explore the universe of human proteins at neXtProt for ANXA13: NX_P27216

Explore proteomics data for ANXA13 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ANXA13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001003954.1  NP_004297.2  

    ENSEMBL proteins: 
     ENSP00000262219   ENSP00000390809   ENSP00000429358  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANXA: Annexins

    4 InterPro protein domains:
     IPR009166 AnnexinXIII
     IPR018502 Annexin_repeat
     IPR001464 Annexin
     IPR018252 Annexin_repeat_CS

    Graphical View of Domain Structure for InterPro Entry P27216

    ProtoNet protein and cluster: P27216

    2 Blocks protein domains:
    IPB001464 Annexin
    IPB002392 Annexin type V signature


    UniProtKB/Swiss-Prot: ANX13_HUMAN, P27216
    Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid
    Similarity: Belongs to the annexin family
    Similarity: Contains 4 annexin repeats


    Find genes that share domains with ANXA13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for ANXA13:
    annexin A13,calcium and phospholipid binding protein

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001786phosphatidylserine binding IDA15813707
    GO:0005509calcium ion binding IEA--
    GO:0005544calcium-dependent phospholipid binding IEA--
    GO:0031210NOT phosphatidylcholine binding IDA15813707
    GO:1901611phosphatidylglycerol binding IDA15813707
         
    Find genes that share ontologies with ANXA13           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ANXA13

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ANX13_HUMAN, P27216: Cell membrane. Note=Associated with the plasma membrane of undifferentiated, proliferating
    crypt epithelial cells as well as differentiated villus enterocytes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    nucleus2
    golgi apparatus1

    Gene Ontology (GO): Selected cellular component terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0005886plasma membrane NAS1530946
    GO:0016323basolateral plasma membrane ISS--
    GO:0016324apical plasma membrane ISS--
    GO:0045121membrane raft ISS--

    Find genes that share ontologies with ANXA13           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANXA13
    Interactions:

        Search GeneGlobe Interaction Network for ANXA13

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for ANXA13 (P272163 ENSP000002622194) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NMT1P304193, ENSP000002589604I2D: score=1 STRING: ENSP00000258960
    KIFC3Q9BVG83, ENSP000003689764I2D: score=1 STRING: ENSP00000368976
    NEDD4P469343, ENSP000003455304I2D: score=1 STRING: ENSP00000345530
    ACTA1P681333, ENSP000003556454I2D: score=1 STRING: ENSP00000355645
    ACTG1P632613I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030154cell differentiation NAS1530946
    GO:0042997negative regulation of Golgi to plasma membrane protein transport ISS--
    GO:0042998positive regulation of Golgi to plasma membrane protein transport ISS--

    Find genes that share ontologies with ANXA13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ANXA13 (ANX13)

    1 HMDB Compound for ANXA13    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ANXA13 gene (2 alternative transcripts): 
    NM_001003954.1  NM_004306.2  

    Unigene Cluster for ANXA13:

    Annexin A13
    Hs.181107  [show with all ESTs]
    Unigene Representative Sequence: NM_001003954
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000262219(uc003yqt.3) ENST00000419625(uc003yqu.3) ENST00000520519
    ENST00000523822 ENST00000520591 ENST00000519045
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    Additional mRNA sequence: 

    AJ306450.1 AK223374.1 AK290281.1 BC125158.1 CR541838.1 Z11502.1 

    3 DOTS entries:

    DT.453956  DT.91732113  DT.120638905 

    Selected AceView cDNA sequences (see all 27):

    BM824630 NM_001003954 NM_004306 AI984289 AJ306450 BG747425 T28629 BG248802 
    CR541838 AK057781 BG470198 AI927400 Z11502 BX280061 AW295277 BP370194 
    BG385819 BG542398 BM792420 AI678696 BE293184 BG823061 BG385716 AW296908 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ANXA13    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                    -     -                                                                     
    SP2:              -     -     -                                                                     
    SP3:                          -                                                                     
    SP4:                                                                                                


    ECgene alternative splicing isoforms for ANXA13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANXA13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTAACTGGAT
    ANXA13 Expression
    About this image


    ANXA13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Epithelial Cells
             Duct Cells Pancreatic Ducts
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 2 entries
             Hindgut
     
     Kidney (Urinary System)
             Presumptive Podocytes Podocyte Layer
     
     Pancreas (Endocrine System)
             Duct Cells Pancreatic Ducts
     
     Ovary (Reproductive System)
             Oviduct
    ANXA13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANXA13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.181107

    UniProtKB/Swiss-Prot: ANX13_HUMAN, P27216
    Tissue specificity: Gut specific

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ANXA13 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Anxa131 , 5 annexin A131, 5 85.28(n)1
    86.69(a)1
      15 (24.66 cM)5
    697871  NM_027211.21  NP_081487.11 
     583418745 
    chicken
    (Gallus gallus)
    Aves ANXA131 annexin A13 71.26(n)
    72.13(a)
      420342  NM_001199501.1  NP_001186430.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANXA136
    annexin A13
    70(a)
    1 ↔ 1
    4(6671243-6682567)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.251152 Xenopus laevis transcribed sequence with weak similarity more 75.58(n)    CB205973.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.165042 Transcribed sequence with weak similarity to protein more 77.77(n)    CK028447.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta AnnIX3 actin binding 50(a)
    (best of 3)
      93B10   --
    worm
    (Caenorhabditis elegans)
    Secernentea nex-23
    nex-11
    Annexin3
    nex-11
    46(a)
    (best of 2)3
    49.06(n)1
    42.52(a)1
      III(10397630-10399688)3
    1757141  NM_065708.61  NP_498109.11 
    rice
    (Oryza sativa)
    Liliopsida Os09g03949001 Os09g0394900 48.26(n)
    39.87(a)
      4346972  NM_001069631.1  NP_001063096.1 


    ENSEMBL Gene Tree for ANXA13 (if available)
    TreeFam Gene Tree for ANXA13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANXA13 gene
    ANXA32  ANXA62  ANXA52  ANXA12  ANXA92  ANXA22  ANXA72  ANXA82  
    ANXA112  ANXA8L22  ANXA102  ANXA8L12  ANXA42  
    15 SIMAP similar genes for ANXA13 using alignment to 3 protein entries:     ANX13_HUMAN (see all proteins):
    ANXA7    DKFZp686H02120    ANXA8L2    ANXA4    ANXA3    ANXA6
    ANXA2    ANXA11    ANXA1    ANXA2P2    ANXA5    ANXA8
    ANXA10    ANXA9    ANXA8L1

    Find genes that share paralogs with ANXA13           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANXA13 (see all 1299)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2008307191,2
    Cuntested1124724923(+) CCATTC/TCTTTG 4 E G mis11Minor allele frequency- T:0.00EU 1323
    rs1844886041,2
    C--124692611(+) CAATGA/GATGAC 2 -- ds50010--------
    rs1902221241,2
    --124692621(+) CAACTA/GTGATT 2 -- ds50010--------
    rs1394499581,2
    --124692628(+) GATTAC/TTGGGC 2 -- ds50010--------
    rs78329601,2
    C,F,H--124692711(+) ACACAG/AAATCT 2 -- ds500111Minor allele frequency- A:0.03NS EA NA WA 1308
    rs1498657491,2
    --124692730(+) GGAACA/CAATTC 2 -- ds50010--------
    rs1824462311,2
    --124692809(+) AGAGGA/GAAGAC 2 -- ds50010--------
    rs100890311,2
    C,F,H--124692832(+) AATGTC/ATAGAG 2 -- ds50015Minor allele frequency- A:0.01NS EA CSA 416
    rs1866333191,2
    --124692893(+) TACAGC/TTTACA 2 -- ds50010--------
    rs1904058331,2
    C--124692951(+) TAAAAA/GATGTA 2 -- ds50010--------

    HapMap Linkage Disequilibrium report for ANXA13 (124693034 - 124749647 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ANXA13:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6373CNV Loss18451855
    nsv831451CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602573    OMIM disorders: --


    Find genes that share disorders with ANXA13           About GenesLikeMe

    Genetic Association Database (GAD): ANXA13

    Export disorders for ANXA13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANXA13 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with ANXA13)
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    1. Comparative genetics and evolution of annexin A13 as the founder gene of vertebrate annexins. (PubMed id 11961095)1, 2, 9 Iglesias J.M....Fernandez M.-P. (Mol. Biol. Evol. 2002)
    2. A strategy for isolation of cDNAs encoding proteins affecting human intestinal epithelial cell growth and differentiation: characterization of a novel gut-specific N-myristoylated annexin. (PubMed id 1530946)1, 2, 9 Wice B.M. and Gordon J.I. (J. Cell Biol. 1992)
    3. Genomic locations of ANX11 and ANX13 and the evolutionary genetics of human annexins. (PubMed id 9503022)1, 3, 9 Morgan R.O....Fernandez M.P. (Genomics 1998)
    4. A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants. (PubMed id 22219177)1, 4 Tao S....Sun J. (Carcinogenesis 2012)
    5. Structure-function relationship in annexin A13, the founder member of the vertebrate family of annexins. (PubMed id 15813707)1, 9 Turnay J....Lizarbe M.A. (Biochem. J. 2005)
    6. Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb. (PubMed id 10871286)1, 9 Plant P.J....Rotin D. (J. Cell Biol. 2000)
    7. Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. (PubMed id 21184583)1 Zlojutro M....Almasy L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation. (PubMed id 20701074)1 Reiske H....Kinch M.S. (Anal. Quant. Cytol. Histol. 2010)
    10. Genome-wide association study of pancreatic cancer in Japanese population. (PubMed id 20686608)4 Low S.K....Sakamoto H. (PLoS ONE 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 312 HGNC: 536 AceView: ANXA13 Ensembl:ENSG00000104537 euGenes: HUgn312
    ECgene: ANXA13 H-InvDB: ANXA13

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ANXA13 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ANXA13 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ANXA13 gene:
    Search GeneIP for patents involving ANXA13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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