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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ANXA11 Gene

protein-coding GIFtS: 62
GCID: GC10M081904

annexin A11

(Previous symbol: ANX11)

Explore 15 diseases affiliated with
ANXA11 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Annexin A11¹ ²		CAP-50² ³
ANX11¹ ² ³ ⁵		CAP50²
Annexin XI² ³		Annexin-11³
Calcyclin-Associated Annexin 50² ³		Autoantigen, 56-KD²
56 KDa Autoantigen² ³		Annexin-11³

External Ids:	HGNC: 535¹	Entrez Gene: 311²	Ensembl: ENSG00000122359⁷	OMIM: 602572⁵	UniProtKB: P50995³

Export aliases for ANXA11 gene to outside databases

Previous GC identifers: GC10M080871 GC10M081136 GC10M082046 GC10M081579 GC10M075758

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ANXA11:

This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins

have unique N-terminal domains and conserved C-terminal domains, which contain the calcium-dependent

phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various

autoimmune diseases. Transcript variants encoding the same isoform have been identified. (provided by RefSeq, Jul

2008)

UniProtKB/Swiss-Prot: ANX11_HUMAN, P50995

Function: Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation

and completion of the terminal phase of cytokinesis

Gene Wiki entry for ANXA11

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ANXA11 gene promoter:
GR GR-beta Bach2 GR-alpha IRF-1 Arnt RSRFC4
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ANXA11 promoter sequence

Search SABiosciences Chromatin IP Primers for ANXA11

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANXA11

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q23 Ensembl cytogenetic band: 10q22.3 HGNC cytogenetic band: 10q22.3

ANXA11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANXA11 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M081904: view genomic region (about GC identifiers)

Start:	81,910,645 bp from pter	End:	81,965,433 bp from pter
Size:	54,789 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ANX11_HUMAN, P50995 (See protein sequence)

Recommended Name: Annexin A11

Size: 505 amino acids; 54390 Da

Subunit: Interacts with S100A6 (By similarity). Interacts with PDCD6 in a calcium-dependent manner. Interacts with

KIF23 during cytokinesis

Subcellular location: Cytoplasm. Melanosome. Nucleus envelope. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle.

Note=Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By

similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope,

with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent

Explore the universe of human proteins at neXtProt for ANXA11: NX_P50995

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P50995

ANXA11 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001148.1 NP_665875.1 NP_665876.1

ENSEMBL proteins:

ENSP00000361305 ENSP00000404412 ENSP00000398610 ENSP00000361308 ENSP00000405009

ENSP00000391296 ENSP00000414642 ENSP00000353827 ENSP00000265447 ENSP00000441748

ENSP00000441400

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	ProSpec Recombinant Protein for ANXA11
	Uscn Proteins for ANXA11

Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005635	nuclear envelope	NAS	12577318
GO:0005654	nucleoplasm	NAS	12577318
GO:0005737	cytoplasm	IDA	7508441
GO:0005819	spindle	IDA	12805373
GO:0030496	midbody	IDA	15197175

ANXA11 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ANXA11 for domains About GeneDecksing

4 InterPro domains/families:

IPR001464 Annexin

IPR018252 Annexin_repeat_CS

IPR008157 AnnexinXI

IPR018502 Annexin_repeat

Graphical View of Domain Structure for InterPro Entry P50995

ProtoNet protein and cluster: P50995

1 Blocks protein family: IPB001464 Annexin

UniProtKB/Swiss-Prot: ANX11_HUMAN, P50995

Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid

Similarity: Belongs to the annexin family

Similarity: Contains 4 annexin repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ANX11_HUMAN, P50995

Function: Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation

and completion of the terminal phase of cytokinesis

Genatlas biochemistry entry for ANXA11:

annexin A11,calcium and phospholipid binding protein,two alternatively spliced isoforms

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANXA11

Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--
GO:0005515	protein binding	IPI	9268363
GO:0005544	calcium-dependent phospholipid binding	IEA	--
GO:0008429	phosphatidylethanolamine binding	IEA	--
GO:0044548	S100 protein binding	IPI	19724273

ANXA11 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ANXA11

STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

5/548 Interacting proteins for ANXA11 (P50995^{2, 3} ENSP00000265447⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 548)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TRIP13	Q15645²^,³	MINT-7947479 I2D: score=1
UBA5	Q9GZZ9²^,³	MINT-7947479 I2D: score=1
ALG2	Q9H553³, ENSP00000417764⁴	I2D: score=2 STRING: ENSP00000417764
S100A6	P06703³, ENSP00000357708⁴	I2D: score=2 STRING: ENSP00000357708
SRI	P30626³, ENSP00000265729⁴	I2D: score=2 STRING: ENSP00000265729

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006909	phagocytosis	IEP	9188810
GO:0007049	cell cycle	IEA	--
GO:0007109	cytokinesis, completion of separation	IMP	15197175
GO:0051592	response to calcium ion	IDA	9188810

ANXA11 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

ANXA11 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ANXA11

1 HMDB Compound for ANXA11 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

2 Novoseek chemical compound relationships for ANXA11 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
phospholipid	34.8	3	1299619 (1), 7508441 (1)
calcium	9.68	7	9188810 (3), 12805373 (2), 8639854 (1)

Search CenterWatch for drugs/clinical trials and news about ANXA11 / ANX11

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ANXA11 gene (3 alternative transcripts):

NM_001157.2 NM_145868.1 NM_145869.1

Unigene Cluster for ANXA11:

Annexin A11

Hs.530291 [show with all ESTs]

Unigene Representative Sequence: NM_145869

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000372231(uc001kbt.1) ENST00000422982(uc001kbs.1 uc010qly.1)

ENST00000438331(uc001kbr.1) ENST00000372234(uc001kbu.1) ENST00000463340

ENST00000447489 ENST00000475974 ENST00000481805 ENST00000445524 ENST00000437799

ENST00000463657 ENST00000474545 ENST00000360615 ENST00000265447(uc010qlx.1)

ENST00000535999(uc001kbq.1) ENST00000537102

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		hsa-miR-3910 hsa-miR-146b-3p hsa-miR-181c hsa-miR-548v hsa-miR-1271 hsa-miR-520a-5p hsa-miR-124 hsa-miR-204

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Additional cDNA sequence:

AB209770.1 AJ278463.1 AJ278464.1 AJ278465.1 AK000567.1 AK056107.1 AK126287.1 AK222918.1

AK298362.1 AK300509.1 AK301047.1 AL357617.1 BC007564.2 BT019934.1 CR450323.1 L19605.1

24/37 DOTS entries (see all 37):

DT.449904 DT.75182037 DT.100849032 DT.95208551 DT.100849034 DT.100849033 DT.100849011 DT.100697284

DT.121246178 DT.92458913 DT.92458908 DT.121246149 DT.101985389 DT.95373951 DT.91870206 DT.100849009

DT.121246298 DT.97860541 DT.100849014 DT.100849028 DT.100849030 DT.91656372 DT.91794085 DT.92458920

24/816 AceView cDNA sequences (see all 816):

BU145707 BQ060818 NM_145868 BG760902 AW027760 AA384611 BE857961 CR591981

AW675266 H93242 AW316919 AL550520 AL527256 BM810802 CB160137 W46456

H50865 BU943489 AU105253 CR606218 AA808938 AI005052 H81555 AA363111

GeneLoc Exon Structure

5/20 Alternative Splicing Database (ASD) splice patterns (SP) for ANXA11 (see all 20) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4	^	5a	·	5b	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12a	·	12b	^	13	^	14	^	15a	·	15b	·	15c	·	15d	^	16a	·	16b	^
SP1:									-		-		-		-		-		-		-		-								-				-		-
SP2:									-		-		-		-		-		-		-		-		-		-				-				-		-
SP3:									-		-		-		-		-		-		-		-		-		-		-		-				-		-
SP4:									-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-		-
SP5:									-		-		-		-		-		-		-		-		-		-		-		-				-		-						-		-		-

ExUns:	17	^	18a	·	18b	^	19	^	20	^	21a	·	21b	^	22	^	23	^	24	^	25	^	26a	·	26b	^	27a	·	27b	·	27c
SP1:					-								-
SP2:					-								-
SP3:					-								-
SP4:	-		-		-		-						-
SP5:					-

ECgene alternative splicing isoforms for ANXA11

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ANXA11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGTCTCGCA

About this image

ANXA11 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

5 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Gut Tube

Hindgut

Hindgut Endoderm Cells

Endoderm

Gut Tube

Midgut

Midgut Endoderm Cells

Endoderm

Gut Tube

Gut Tube

Umbilical Cord

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

See ANXA11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANXA11

SOURCE GeneReport for Unigene cluster: Hs.530291

SABiosciences Custom PCR Arrays for ANXA11

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ANXA11 gene from 8/27 species (see all 27) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ANXA11¹	annexin A11	74.33(n) 82.34(a)		423637 NM_001012903.2 NP_001012921.2
lizard (Anolis carolinensis)	Reptilia	ANXA11⁶	--	78(a)	1 ↔ 1	GL343495.1(319704-338086)
African clawed frog (Xenopus laevis)	Amphibia	Xl.13331²	Xenopus laevis transcribed sequence with weak similarity more	76.6(n)		BU906951.1
zebrafish (Danio rerio)	Actinopterygii	anxa11a²	annexin A11a	78.43(n)		368215 AY178801.1
fruit fly (Drosophila melanogaster)	Insecta	AnnIX^{1 , 3}	actin binding³ Annexin IX¹	52(a) (best of 3)³ 58.39(n)¹ 54.84(a)¹		93B10³ 42492¹ NM_206531.1¹ NP_996253.1¹
worm (Caenorhabditis elegans)	Secernentea	nex-2³	Annexin	48(a) (best of 3)		III(10397630-10399688) --
thale cress (Arabidopsis thaliana)	eudicotyledons	ANNAT5⁶ ANNAT1⁶ (see all 8)	annexin D1 (see all 8)	35(a) 33(a) (see all 8)	many ↔ many many ↔ many (see all 8)	1(25519442-25520774) 1(13225197-13227195)
rice (Oryza sativa)	Liliopsida	-- -- (see all 9)	annexin, putative, expressed (see all 9)	38(a) 37(a) (see all 9)	many ↔ many many ↔ many (see all 9)	9(13705487-13710510) 8(20456985-20458908)

ENSEMBL Gene Tree for ANXA11 (if available)
TreeFam Gene Tree for ANXA11 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ANXA11 gene

ANXA3² ANXA6² ANXA1² ANXA5² ANXA9² ANXA2² ANXA7² ANXA8²

ANXA8L2² ANXA10² ANXA8L1² ANXA4² ANXA13²

15 SIMAP similar genes for ANXA11 using alignment to 7 protein entries: ANX11_HUMAN (see all proteins):

DKFZp686H02120 ANXA4 ANXA8L2 ANXA5 ANXA6 ANXA3

ANXA13 ANXA2P2 ANXA10 ANXA8 ANXA1 ANXA7

ANXA2 ANXA9 ANXA8L1

ANXA11 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs35914986^1,2	C,	--	81914579(+)	`ACACA-/CCCTTC`	3	--	ds500¹		0	--	--	--	--
rs35176036^1,2	C,F,	--	81914735(+)	`CCTTAC/TGAGTC`	3	--	ds500¹		5		NA	128
rs3748242^1,2	C,F,H,	--	81914787(-)	`CTTACG/ATAGAG`	3	--	ds500¹ ese³		28		EA NA NS	4356
rs141534806^1,2		--	81914923(+)	`TGTGG-/AAACAA`	3	--	ut3¹		0	--	--	--	--
rs201493018^1,2		--	81915055(+)	`GGCCC-/TTTTTT`	3	--	ut3¹		0	--	--	--	--
rs55965241^1,2	C	--	81915056(+)	`GCCCTT/-TTTTT`	3	--	ut3¹		1		NA	2
rs2789686^1,2	C,F,A,H,	--	81915136(+)	`CTACCC/TTCTCA`	3	--	ut3¹ ese³		30		NA NS EA WA CSA	2662
rs76487007^1,2	F,	--	81915144(+)	`TCAGGC/TACGCC`	3	--	ut3¹		1		WA	118
rs191624986^1,2		--	81915167(+)	`CTCAGC/TGAGGA`	3	--	ut3¹		0	--	--	--	--
rs140723641^1,2		--	81915173(+)	`GAGGAC/TACGGT`	3	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ANXA11 (81910645 - 81965433 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ANXA11: --
Human Gene Mutation Database (HGMD): ANXA11

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ANXA11 for disorders           About GeneDecksing

OMIM gene information: 602572    OMIM disorders: --

15 diseases for ANXA11:    About MalaCards

papillary hidradenoma hidradenoma lupus erythematosus syringoma

rheumatoid arthritis osteonecrosis endocarditis arthritis

sarcoidosis alzheimer's disease ovarian cancer pancreatic cancer

lung cancer pancreatitis cholesterol

1 disease from the University of Copenhagen DISEASES database for ANXA11:

Sarcoidosis

6 Novoseek disease relationships for ANXA11 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
sclerosis systemic	34.2	1	7699691 (1)
autoimmune diseases	32	8	11035417 (3), 7699691 (3), 12805373 (1)
lupus erythematosus systemic	28.3	1	7699691 (1)
rheumatoid arthritis	17.9	1	7699691 (1)
tumors	0	4	17982121 (2), 19422301 (1), 19484149 (1)
cancer	0	1	17982121 (1)

Human Genome Epidemiology (HuGE) Navigator: ANXA11 (6 documents)

Export disorders for ANXA11 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ANXA11 gene, integrated from 9 sources (see all 58):
(articles sorted by number of sources associating them with ANXA11)

Utopia: connect your pdf to the dynamic
world of online information

The 56K autoantigen is identical to human annexin XI. (PubMed id 7508441)^{1, 2, 3, 9} Misaki Y.... van Venrooij W.J. (1994)
Dissecting the cellular functions of annexin XI using recombinant human annexin XI-specific autoantibodies cloned by phage display. (PubMed id 12805373)^{1, 2, 9} Farnaes L. and Ditzel H.J. (2003)
ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner. (PubMed id 11883939)^{1, 2, 9} Satoh H.... Maki M. (2002)
Annexin A11 (ANXA11) gene structure as the progenitor of paralogous annexins and source of orthologous cDNA isoforms. (PubMed id 11013079)^{1, 2, 9} Bances P....Fernandez M.-P. (2000)
Genomic locations of ANX11 and ANX13 and the evolutionary genetics of human annexins. (PubMed id 9503022)^{1, 3, 9} Morgan R.O....Fernandez M.P. (1998)
Identification of Alix-type and non-Alix-type ALG-2-binding sites in human phospholipid scramblase 3: differential binding to an alternatively spliced isoform and amino acid-substituted mutants. (PubMed id 18256029)^{1, 2, 9} Shibata H....Maki M. (2008)
Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)^{1, 2} Chi A....Hunt D.F. (2006)
Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis. (PubMed id 15197175)^{1, 2} Tomas A.... Moss S.E. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope. (PubMed id 12601007)^{1, 2} Tomas A. and Moss S.E. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 311	HGNC: 535	AceView: ANXA11	Ensembl:ENSG00000122359	euGenes: HUgn311
ECgene: ANXA11	H-InvDB: ANXA11

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ANXA11	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ANXA11 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ANXA11 gene:
Search GeneIP for patents involving ANXA11

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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