Aliases for ANXA1 Gene
External Ids for ANXA1 Gene
Previous HGNC Symbols for ANXA1 Gene
Previous GeneCards Identifiers for ANXA1 Gene
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
GeneCards Summary for ANXA1 Gene
ANXA1 (Annexin A1) is a Protein Coding gene. Diseases associated with ANXA1 include taeniasis and brain edema. Among its related pathways are Signaling by GPCR and Interleukin receptor SHC signaling. GO annotations related to this gene include calcium ion binding and receptor binding. An important paralog of this gene is ANXA9.
UniProtKB/Swiss-Prot for ANXA1 Gene
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity
Cell adhesion molecules (CAMs) are a large family of transmembrane proteins that are involved in the binding of a cell to another cell or to the extracellular matrix. They have roles in cell proliferation, differentiation, motility, trafficking, apoptosis and tissue architecture.