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Aliases for ANTXRL Gene

Aliases for ANTXRL Gene

  • Anthrax Toxin Receptor-Like 2 3

External Ids for ANTXRL Gene

Previous GeneCards Identifiers for ANTXRL Gene

  • GC10U900624
  • GC10P047130
  • GC10P047658
  • GC10M045383

Summaries for ANTXRL Gene

GeneCards Summary for ANTXRL Gene

ANTXRL (Anthrax Toxin Receptor-Like) is a Protein Coding gene. GO annotations related to this gene include receptor activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANTXRL Gene

Genomics for ANTXRL Gene

Regulatory Elements for ANTXRL Gene

Transcription factor binding sites by QIAGEN in the ANTXRL gene promoter:

Genomic Location for ANTXRL Gene

Start:
46,286,345 bp from pter
End:
46,330,266 bp from pter
Size:
43,922 bases
Orientation:
Plus strand

Genomic View for ANTXRL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANTXRL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANTXRL Gene

Proteins for ANTXRL Gene

  • Protein details for ANTXRL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NF34-ANTRL_HUMAN
    Recommended name:
    Anthrax toxin receptor-like
    Protein Accession:
    A6NF34
    Secondary Accessions:
    • H3BPS2

    Protein attributes for ANTXRL Gene

    Size:
    631 amino acids
    Molecular mass:
    70629 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANTXRL Gene

Proteomics data for ANTXRL Gene at MOPED

Post-translational modifications for ANTXRL Gene

No Post-translational modifications

Other Protein References for ANTXRL Gene

No data available for DME Specific Peptides for ANTXRL Gene

Domains for ANTXRL Gene

Protein Domains for ANTXRL Gene

Suggested Antigen Peptide Sequences for ANTXRL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NF34

UniProtKB/Swiss-Prot:

ANTRL_HUMAN :
  • A6NF34
Domain:
  • Contains 1 VWFA domain.
Family:
  • Belongs to the ATR family.
genes like me logo Genes that share domains with ANTXRL: view

No data available for Gene Families for ANTXRL Gene

Function for ANTXRL Gene

Gene Ontology (GO) - Molecular Function for ANTXRL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004872 receptor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ANTXRL: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANTXRL Gene

Localization for ANTXRL Gene

Subcellular locations from UniProtKB/Swiss-Prot for ANTXRL Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for ANTXRL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ANTXRL: view

No data available for Subcellular locations from COMPARTMENTS for ANTXRL Gene

Pathways for ANTXRL Gene

SuperPathways for ANTXRL Gene

No Data Available

Interacting Proteins for ANTXRL Gene

Gene Ontology (GO) - Biological Process for ANTXRL Gene

None

No data available for Pathways by source for ANTXRL Gene

Transcripts for ANTXRL Gene

mRNA/cDNA for ANTXRL Gene

(16) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANTXRL Gene

Anthrax toxin receptor-like:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANTXRL

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ANTXRL
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANTXRL Gene

No ASD Table

Relevant External Links for ANTXRL Gene

GeneLoc Exon Structure for
ANTXRL
ECgene alternative splicing isoforms for
ANTXRL

Expression for ANTXRL Gene

mRNA expression in normal human tissues for ANTXRL Gene

mRNA differential expression in normal tissues according to GTEx for ANTXRL Gene

This gene is overexpressed in Testis (36.5).

SOURCE GeneReport for Unigene cluster for ANTXRL Gene Hs.538515

genes like me logo Genes that share expressions with ANTXRL: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for ANTXRL Gene

Orthologs for ANTXRL Gene

This gene was present in the common ancestor of mammals.

Orthologs for ANTXRL Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC782834 35
  • 67.57 (n)
  • 51.35 (a)
dog
(Canis familiaris)
Mammalia LOC611121 35
  • 63.48 (n)
  • 49.13 (a)
mouse
(Mus musculus)
Mammalia Antxrl 35
  • 62.86 (n)
  • 46.7 (a)
Antxrl 16
rat
(Rattus norvegicus)
Mammalia Antxrl 35
  • 59.7 (n)
  • 44.46 (a)
Species with no ortholog for ANTXRL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANTXRL Gene

ENSEMBL:
Gene Tree for ANTXRL (if available)
TreeFam:
Gene Tree for ANTXRL (if available)

Paralogs for ANTXRL Gene

Selected SIMAP similar genes for ANTXRL Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ANTXRL: view

No data available for Paralogs for ANTXRL Gene

Variants for ANTXRL Gene

Sequence variations from dbSNP and Humsavar for ANTXRL Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs2860238 -- 46,315,791(-) GTGCC(A/G)AAATG intron-variant
rs2860239 -- 46,315,986(-) TGTAT(A/G)AGTGT intron-variant
rs2860240 -- 46,316,015(-) AAGAG(A/C)CTCGG intron-variant
rs2860590 -- 46,315,629(-) GAAGA(A/G)GAGTT intron-variant
rs2999402 -- 46,304,376(-) AGCCT(A/T)TGTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANTXRL Gene

Variant ID Type Subtype PubMed ID
dgv252e1 CNV Complex 17122850
dgv254e1 CNV Complex 17122850
nsv516485 CNV Gain+Loss 19592680
esv34875 CNV Gain 17911159
nsv510991 OTHER Complex 20534489
dgv257e1 CNV Complex 17122850
dgv258e1 CNV Complex 17122850
nsv8636 CNV Gain+Loss 18304495
nsv436102 CNV Deletion 17901297
nsv7203 OTHER Inversion 18451855
dgv656n71 CNV Gain 21882294
esv2736163 CNV Deletion 23290073
dgv260e1 CNV Complex 17122850
dgv23e55 CNV Loss 17911159
dgv24e55 CNV Gain 17911159
nsv470934 CNV Gain 18288195
nsv818758 CNV Gain 17921354
dgv264e1 CNV Complex 17122850
dgv666n71 CNV Gain 21882294
essv16686 CNV CNV 17122850
dgv267e1 CNV Complex 17122850
esv28391 CNV Loss 19812545
nsv820578 CNV Duplication 20802225
nsv831857 CNV Gain 17160897
dgv680n71 CNV Loss 21882294
dgv681n71 CNV Gain+Loss 21882294
dgv682n71 CNV Loss 21882294
dgv683n71 CNV Gain 21882294
nsv442574 CNV CNV 18776908
nsv470935 CNV Loss 18288195
dgv83n27 CNV Loss 19166990
dgv84n27 CNV Loss 19166990
dgv85n27 CNV Gain 19166990
nsv818760 CNV Gain 17921354
nsv467059 CNV Gain 19166990
dgv685n71 CNV Gain 21882294
nsv469676 CNV Complex 16826518
nsv471667 CNV Gain 15918152
nsv895278 CNV Gain+Loss 21882294
dgv27e55 CNV Gain 17911159
dgv28e55 CNV Gain 17911159
esv2750959 CNV Loss 17911159
dgv268e1 CNV Complex 17122850
dgv686n71 CNV Gain 21882294
nsv895285 CNV Gain 21882294
dgv687n71 CNV Gain+Loss 21882294
dgv688n71 CNV Gain 21882294
dgv88n27 CNV Gain 19166990
dgv89n27 CNV Loss 19166990
dgv689n71 CNV Gain 21882294
nsv895294 CNV Gain+Loss 21882294
nsv831859 CNV Gain+Loss 17160897
dgv691n71 CNV Gain 21882294
dgv692n71 CNV Gain 21882294
nsv895304 CNV Gain+Loss 21882294
dgv693n71 CNV Gain 21882294
nsv895321 CNV Loss 21882294
esv2475335 OTHER Inversion 19546169
esv5777 OTHER Inversion 19470904
nsv6543 CNV Insertion 18451855
dgv90n27 CNV Gain 19166990
dgv694n71 CNV Gain 21882294
dgv695n71 CNV Gain 21882294
esv2736351 CNV Deletion 23290073
esv2736363 CNV Deletion 23290073
nsv24140 CNV Loss 16902084
nsv438173 CNV Loss 16468122
nsv895336 CNV Gain 21882294
nsv437116 CNV Loss 16327808

Relevant External Links for ANTXRL Gene

HapMap Linkage Disequilibrium report
ANTXRL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANTXRL Gene

Disorders for ANTXRL Gene

No disorders were found for ANTXRL Gene.

No data available for UniProtKB/Swiss-Prot for ANTXRL Gene

Publications for ANTXRL Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ANTXRL Gene

Sources for ANTXRL Gene

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