ANTXRL Gene
protein-coding GIFtS: 33
GCID: GC10P047658
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anthrax toxin receptor-like
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Aliases
for ANTXRL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 8
| Aliases |
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| Anthrax Toxin Receptor-Like1 2 |
| External Ids: | HGNC: 272771 | Entrez Gene: 1959772 | Ensembl: ENSG000001982507 | UniProtKB: A6NF343 | | ORGUL members: | |
|---|
| NONCODE:n372016 n372289 n372290 n371670 n372288 | |
Export aliases for ANTXRL gene to outside databasesPrevious GC identifers: GC10U900624 GC10P047130 GC10M045383
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Summaries
for ANTXRL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ANTXRL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NT_077570.1 NC_018921.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANTXRL gene promoter:
RFX1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANTXRL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANTXRL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q11.22 Ensembl cytogenetic band: 10q11.22 HGNC cytogenetic band: 10q11.22ANTXRL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P047658: view genomic region
(about GC identifiers)
Start:
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47,657,581 bp from pter |
End:
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47,701,446 bp from pter |
Size:
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43,866 bases |
Orientation:
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plus strand |
ORGUL member locations:
Legend (see complete legend)
- n371670
- n372289
- n372288
- n372016
- n372290
47658233 47679938 47701642 chr10
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Proteins
for ANTXRL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANTRL_HUMAN, A6NF34 (See
protein sequence)Recommended Name: Anthrax toxin receptor-like precursor Size: 565 amino acids; 62905 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)Explore the universe of human proteins at neXtProt for ANTXRL: NX_A6NF34
ANTXRL Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000458076 ENSP00000457543 ENSP00000455449 ENSP00000457642 ENSP00000455843
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
ANTXRL for ontologies About GeneDecksing
ANTXRL Antibody Products:
Assay Products for ANTXRL: |
Protein
Domains /
Families
for ANTXRL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANTXRL for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A6NF34ProtoNet protein and cluster: A6NF34 UniProtKB/Swiss-Prot: ANTRL_HUMAN, A6NF34Similarity: Belongs to the ATR familySimilarity: Contains 1 VWFA domain |
Function
for ANTXRL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANTXRL |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004872 | receptor activity |
IEA | -- | | GO:0046872 | metal ion binding |
IEA | -- |
ANTXRL for ontologies About GeneDecksing
|
Pathways & Interactions
for ANTXRL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANTXRL
|
Drugs & Compounds
for ANTXRL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANTXRL
Search CenterWatch for drugs/clinical trials and news about ANTXRL / ANTRL 
|
Transcripts
for ANTXRL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for ANTXRL: Anthrax toxin receptor-like Hs.538515 [show with all ESTs]Unigene Representative Sequence: XR_1591586 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000441923 ENST00000424375(uc001jel.2) ENST00000447511 ENST00000564569
ENST00000434908 ENST00000537271
Additional cDNA sequence: AK057316.1 XR_159066.1 XR_159158.2 XR_159198.1 XR_171854.1 2 DOTS entries: DT.95133516 DT.97764207
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ANTXRL About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 |
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| SP1: | | | | | | | | | - | | | | - | | | | | | |
| SP2: | | | - | | | | | | - | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ANTXRL
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Expression
for ANTXRL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANTXRL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGTGTTGT
About this image
SOURCE GeneReport for Unigene cluster: Hs.538515
SABiosciences Custom PCR Arrays for ANTXRL
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANTXRL
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ANTXRL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANTXRL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANTXRL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANTXRL |
Orthologs
for ANTXRL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ANTXRL gene from 4/8 species (see all 8) About this table
ENSEMBL Gene Tree for ANTXRL (if available)
TreeFam Gene Tree for ANTXRL (if available) |
Paralogs
for ANTXRL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANTXRL gene
- ANTXR22 ANTXR12
3 SIMAP similar genes for ANTXRL using alignment to 5 protein entries: ANTRL_HUMAN (see all proteins):ANTXR1 ANTXR1/NNG1 fusion ANTXR2
ANTXRL for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ANTXRL
PGOHUM00000262833 PGOHUM00000262835
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Genomic Variants
for ANTXRL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANTXRL (47657581 - 47701446 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 51 variations for ANTXRL
15/48 CNVs (see all 48): 34555 53968 29855 53341 3798 1483 9152 8649 29591 8646 34572 53684 48545 2153 4688
1 Indel: 11474
2 Inversions: 103319 59675 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for ANTXRL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ANTXRL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANTXRL gene integrated from 9 sources:
(articles sorted by number of sources associating them with ANTXRL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for ANTXRL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ANTXRL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANTXRL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANTXRL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANTXRL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ANTXRL gene:
Search GeneIP for patents involving ANTXRL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANTXRL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANTXRL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANTXRL | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | Browse OriGene untagged cDNA clones in CMV expression vector | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXRL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ANTXRL | | OriGene Custom Protein Services for ANTXRL | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANTXRL | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANTXRL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANTXRL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANTXRL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANTXRL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANTXRL |
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 |  |  |  | |
| | | | Search Tocris compounds for ANTXRL |
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 | | | ANTXRL Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANTXRL |
|  |  |  | | | | Search ThermoFisher Antibodies for ANTXRL |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANTXRL |
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Last full update: 18 Mar 2013 -
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