Aliases for ANTXR2 Gene
External Ids for ANTXR2 Gene
Previous GeneCards Identifiers for ANTXR2 Gene
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
GeneCards Summary for ANTXR2 Gene
ANTXR2 (Anthrax Toxin Receptor 2) is a Protein Coding gene. Diseases associated with ANTXR2 include hyaline fibromatosis syndrome and hyalinosis, inherited systemic. Among its related pathways are Infectious disease and Cellular roles of Anthrax toxin. GO annotations related to this gene include receptor activity. An important paralog of this gene is ANTXR1.
UniProtKB/Swiss-Prot for ANTXR2 Gene
Necessary for cellular interactions with laminin and the extracellular matrix.