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ANTXR2 Gene

protein-coding   GIFtS: 60

GC04M081045
anthrax toxin receptor 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for ANTXR2

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CMG-2 1, 2, 3
CMG2 1, 2, 3, 5
FLJ31074 1, 2
ISH 2, 5
JHF 2, 5
MGC111533 2
MGC45856 2
Descriptions
Capillary morphogenesis gene 2 protein 3
anthrax toxin receptor 2 2
capillary morphogenesis protein 2 2
External Ids
HGNC: 217321
Entrez Gene: 1184292
UniProtKB: P583353
Ensembl: ENSG000001632977
Search outside databases for aliases for ANTXR2 gene

Previous GC identifers: GC04M081219 GC04M081285 GC04M081183

Summaries
for ANTXR2

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for ANTXR2:
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin,
suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause
juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants
encoding different isoforms have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: ANTR2_HUMAN, P58335
Function: Necessary for cellular interactions with laminin and the extracellular matrix

Gene Wiki entry for ANTXR2

Genomic Location
for ANTXR2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ANTXR2 gene  

Entrez Gene cytogenetic band: 4q21.21   Ensembl cytogenetic band:  4q21.21   HGNC cytogenetic band: 4q21.3

ANTXR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M081045:     (about GC identifiers)

Start:
 81,045,749 bp from pter
End:
 81,213,650 bp from pter
Size:
 167,902 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000004.10  NT_016354.18  

Proteins
for ANTXR2

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: ANTR2_HUMAN, P58335 (See protein sequence)
Recommended Name: Anthrax toxin receptor 2 precursor  
Size: 489 amino acids; 53692 Da
Subunit: Binds laminin, and possibly also collagen type IV. Binds to the protective antigen (PA) of
Bacillus anthracis in a divalent cation-dependent manner, with the following preference: calcium >
manganese > magnesium > zinc. Binding of PA leads to heptamerization of the receptor-PA complex
Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Note=Expressed
at the cell surface
Subcellular location: Isoform 2: Endoplasmic reticulum membrane; Single-pass type I membrane
protein. Note=Expressed predominantly within the endoplasmic reticulum and not at the plasma
membrane
Subcellular location: Isoform 3: Secreted
Miscellaneous: Upon binding of the protective antigen (PA) of Bacillus anthracis the complex moves
to glycosphingolipid-rich lipid rafts, where it is internalized via a clathrin-dependent pathway
PDB structures from and Proteopedia :
1SHT (3D)    1SHU (3D)    1T6B (3D)    1TZN (3D)    
Secondary accessions: Q59E98 Q5JPE9 Q86UI1 Q8N4J8 Q8NB13 Q96NC7
Alternative splicing: 4 isoforms:  P58335-1   P58335-2   P58335-3   P58335-4   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_001139266.1  NP_477520.2  


    ENSEMBL proteins: 
    ENSP00000295465 ENSP00000306185 ENSP00000314883 ENSP00000384028 ENSP00000382324 ENSP00000385575 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    R&D Systems Recombinant & Natural Proteins for ANTXR2 (CMG-2/ANTXR2)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ANTXR2)
    Human Recombinant Proteins from Abnova (ANTXR2)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    5 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    GO:0005783 endoplasmic reticulum IEA--
    GO:0005789 endoplasmic reticulum membrane IEA--
    GO:0005886 plasma membrane IEA--
    GO:0016021 integral to membrane IEA--
    About this table

    Antibodies for ANTXR2: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ANTXR2
    R&D Systems Antibodies for ANTXR2 (CMG-2/ANTXR2)
    Antibodies from Abcam (ANTXR2), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ANTXR2)
    Novus Biologicals Antibodies for ANTXR2

    Assays for ANTXR2: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for ANTXR2

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro domains/families:
     IPR008400 Anthrax_toxin_rcpt_extracel
     IPR017360 Anthrax_toxin_rcpt_2
     IPR008399 Anthrax_toxin_rcpt_C
     IPR002035 VWF_A


       GeneDecks  ANTXR2 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P58335

    ProtoNet protein and cluster: P58335

    2 Blocks protein families:
    IPB002035 Von Willebrand factor type A domain signature
    IPB008399 Anthrax receptor


    UniProtKB/Swiss-Prot: ANTR2_HUMAN, P58335
    Domain: Binding to PA seems to be effected through the VWA domain
    Similarity: Belongs to the ATR family
    Similarity: Contains 1 VWFA domain

    Gene Function
    for ANTXR2

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ANTXR2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ANTXR2)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001145794

                  Applied Biosystems Silencer® siRNAs for ANTXR2

                  Sigma-Aldrich siRNA and siRNA Panels for ANTXR2  
                         Sigma-Aldrich shRNA for ANTXR2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ANTXR2
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001145794
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001145794
                                     untagged cDNA clones in CMV expression vector (see all 3): AY040326 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001145794

    UniProtKB/Swiss-Prot: ANTR2_HUMAN, P58335
    Function: Necessary for cellular interactions with laminin and the extracellular matrix

    3 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004872 receptor activity IEA--
    GO:0005515 protein binding IPI15044490 16564009
    GO:0046872 metal ion binding IEA--
    About this table

    Pathways & Interactions
    for ANTXR2

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


     Gene Network CentralTM Interacting Genes and Proteins Network for  ANTXR2 


    5/7 Interacting proteins for ANTXR2 (P583351, 2 ENSP000003061853) via UniProtKB, MINT, and/or STRING (see all 7 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LRP6O755811, ENSP000002613493EBI-456840, EBI-910915 STRING (score=.861)
    pagA pagA (xeno)P134231EBI-456840, EBI-456868
    SMAD2Q157962MINT-61603
    ANTXR1ENSP000003019453STRING (score=.905)
    COL4A2ENSP000003536543STRING (score=.71)
    About this table

    Drugs & Compounds
    for ANTXR2

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ANTXR2

    Transcripts
    for ANTXR2

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ANTXR2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ANTXR2)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001145794

                  Sigma-Aldrich siRNA and siRNA Panels for ANTXR2  
                         Sigma-Aldrich shRNA for ANTXR2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_058172  

    REFSEQ mRNAs for ANTXR2 gene (2 alternative transcripts): 

    NM_001145794.1   NM_058172.5   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_058172  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001145794
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001145794
                                     untagged cDNA clones in CMV expression vector (see all 3): AY040326 

    Additional cDNA sequence: 

    AB209913.1 AK023450.1 AK055636.1 AL110207.1 AL831848.1 AL832851.1 AY040326.1 AY233452.1 
    BC034001.1 BC042596.1 BC047345.1 BC107876.1 BC114374.1 CR590529.1 CR601853.1 CR607683.1 
    CR612147.1 CR617102.1 

    14 DOTS entries:

    DT.216248  DT.121248282  DT.100819726  DT.95347012  DT.100819722  DT.211486  DT.75184103  DT.121248300 
    DT.121248306  DT.438000  DT.100819725  DT.121248290  DT.121248325  DT.97836198 

    24/221 AceView cDNA sequences (see all 221 ):

    AI074424 BM677527 Z43038 AA974465 CB163917 AI335830 AW452492 CR590529 
    BX280553 BP378380 CD677380 AI434624 CA389296 BQ889566 CR607683 AI274274 
    BM992362 CA407525 CR612147 AI810716 CR617102 AI433847 AA150434 AI674944 

    highest scoring ESTs for ANTXR2:

    AA149312 AK091721 AW239092 AY040326 AY233452 BQ068906 BQ432519 BU177913 BX418954 BX482395 

    Unigene Cluster for ANTXR2:

    Anthrax toxin receptor 2
    Hs.162963  [show with all ESTs]
    Unigene Representative Sequence: NM_058172


    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ANTXR2

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ^ 20
    SP1:                                                                                                              -           -         
    SP2:                                                                    -                                         -                     
    SP3:                                                                                                                                    

    About this scheme

    ECgene alternative splicing isoforms for ANTXR2

    6 Ensembl transcripts including schematic representations:
    ENST00000295465  ENST00000307333  ENST00000346652  ENST00000404191  ENST00000399392  ENST00000403729  

    Expression
    for ANTXR2

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ANTXR2 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ANTXR2

    1 / 2 / 3

    10 probe-sets matching ANTXR2 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    88490_at2 U95-E 1 1.00 1.00 0.93 0.83 -- -- -- -- --
    51714_at2, 3 U95-B 1 1.00 1.00 0.96 1.04 AI830422 0.20 1.00 0.72 1
    58617_at2, 3 U95-B 1 1.00 1.00 0.97 1.15 AA149312 0.80 1.00 0.91 1

    		225524_at2, 3 U133-B 1 1.00 1.00 -- -- AU152178 0.40 1.00 0.76 1

    		228573_at2, 3 U133-B 1 1.00 1.00 -- -- BE673665 0.20 1.00 0.72 1

    		238050_at2 U133-B 1 1.00 1.00 -- -- -- -- -- -- --

    		225524_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		1555536_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		228573_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		238050_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ANTXR2 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.162963

    UniProtKB/Swiss-Prot: ANTR2_HUMAN, P58335
    Tissue specificity: Expressed in prostate, thymus, ovary, testis, pancreas, colon, heart, kidney,
    lung, liver, peripheral blood leukocytes, placenta, skeletal muscle, small intestine and spleen

    Orthologs
    for ANTXR2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for ANTXR2 gene from 5/6 species (see all 6 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 ANTXR21   -- anthrax toxin receptor 2 91.67(n)
    91.8(a)    		 487821  XM_544943.2  XP_544943.2 
    chimpanzee
    (Pan troglodytes)    		 ANTXR21   -- anthrax toxin receptor 2 99.52(n)
    99.59(a)    		 471191  XM_001145091.1  XP_001145091.1 
    cow
    (Bos taurus)    		 ANTXR21   -- anthrax toxin receptor 2 89.69(n)
    89.96(a)    		 510080  NM_001076826.1  NP_001070294.1 
    mouse
    (Mus musculus)    		 Antxr21, 5 55
    		 anthrax toxin receptor 21, 5 83.5(n)1
    84.8(a)1    		 719141  NM_133738.11  NP_598499.11 
     AA6124505  AK0098395  (see all 18)
    chicken
    (Gallus gallus)    		 ANTXR21   -- anthrax toxin receptor 2 70.83(n)
    73.96(a)    		 422580  XM_420539.2  XP_420539.2 
    About this table        Species with no ortholog for ANTXR2

    ENSEMBL Gene Tree for ANTXR2

    Paralogs
    for ANTXR2

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ANTXR2 gene
    ANTXRL2  ANTXR12  

    SNPs/Variants
    for ANTXR2

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/837 NCBI SNPs in ANTXR2 are shown (see all 837 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 235)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 4 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs77471,2
    		A,C,F,H81046086(+) CTTATC/TTTTAG 1 -- ut318Minor allele frequency- T:0.29MN EU EA WA NA 972
    rs131400551,2
    		A,C,F,H81212820(+) CACCCG/TGCACG 1 -- ut514Minor allele frequency- T:0.32EU EA WA 406
    rs68285281,2
    		A,C,F,H81214905(+) aagggT/Ctacag 1 -- ng314Minor allele frequency- C:0.23EU EA WA 418
    --
    rs126476911,2
    		C,F,H81125014(+) AGGGGG/CGGGTG 1 P/A mis1 ese33Minor allele frequency- C:0.14EA WA 296
    rs115579081,2
    		C,F,H81213057(+) AGCTCG/CCGAAA 1 -- ut517Minor allele frequency- C:0.21NA EU EA WA 560
    rs126513881,2
    		C,F,H81215149(+) acataT/Cgcaac 1 -- ng318Minor allele frequency- C:0.39EU EA WA 840
    rs27601,2
    		A,C,F81045936(+) AGAATA/CCTCCC 1 -- ut312Minor allele frequency- C:0.06MN 194
    rs100335401,2
    		F,H81214736(+) tgataT/Ggatct 1 -- ng314Minor allele frequency- G:0.01EU EA WA 418
    rs357981081,2
    		F81117832(+) GAAACC/TCGGTC 1 R/R syn14Minor allele frequency- T:0.05NA EA 362
    rs126441371,2
    		A,C,F,H81165803(+) TAATGC/TTCTGC 1 -- int16Minor allele frequency- T:0.15EU EA WA 598
    About this table

    HapMap Linkage Disequilibrium images for ANTXR2 (up to first 250kb)

    Disorders & Mutations
    for ANTXR2

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 608041   disorders: 228600  236490  

    UniProtKB/Swiss-Prot: ANTR2_HUMAN, P58335

  • Defects in ANTXR2 are the cause of infantile systemic hyalinosis (ISH) [MIM:236490]. This
    autosomal recessive syndrome is similar to JHF, but has an earlier onset and a more severe course.
    Symptoms appear at birth or within the first months of life, with painful, swollen joint
    contractures, osteopenia, osteoporosis and livid red hyperpigmentation over bony prominences.
    Patients develop multiple subcutaneous skin tumors and gingival hypertrophy. Hyaline deposits in
    multiple organs, recurrent infections and intractable diarrhea often lead to death within the
    first 2 years of life. Surviving children may suffer from severely reduced mobility due to joint
    contractures
  • Defects in ANTXR2 are the cause of juvenile hyaline fibromatosis (JHF) [MIM:228600]. JHF
    is an autosomal recessive syndrome that is similar to ISH but takes a milder course. It is
    characterized by hyaline deposition in the dermis, multiple subcutaneous skin tumors and gingival
    hypertrophy, followed by progressive joint contractions, osteopenia and osteoporosis that may lead
    to a severe limitation of mobility

    • 5 Novoseek disease relationships for ANTXR2 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    hyalinosis, systemic infantile 97.20 2 17381430 (1), 19191226 (1)
    anthrax 84.11 22 17381430 (4), 17251181 (2), 15044490 (2), 17054395 (2) (see all 8)
    fibromatosis 79.38 2 17381430 (1), 19191226 (1)
    edema 37.38 1 17251181 (1)
    tumors 0.00 5 17251181 (4), 15044490 (1)
    About this table

    GeneTests: ANTXR2
    Hyalinosis

    Human Gene Mutation Database: ANTXR2
    Human Genome Epidemiology Navigator: ANTXR2 (1 document)

    Medical News
    for ANTXR2

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for ANTXR2

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/37 PubMed articles for ANTXR2 gene (see all 37 ):

    Search for ANTXR2

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ANTXR2

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 118429 HGNC: 21732 AceView: ANTXR2 Ensembl:ENSG00000163297 euGenes: HUgn118429
    ECgene: ANTXR2 H-InvDB: ANTXR2

    Other Databases showing ANTXR2

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing ANTXR2

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    GeneReviewshttp://www.genetests.org/query?gene=ANTXR2

    Licensable Technologies
    for ANTXR2

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for ANTXR2

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ANTXR2:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ANTXR2-related products

     Millipore Custom Antibody & Bulk Services
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     Predesigned and custom siRNAs for ANTXR2 Antibodies for ANTXR2
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
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     Search OriGene for ANTXR2
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     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for ANTXR2

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