ANTXR1 Gene
protein-coding GIFtS: 62
GCID: GC02P069152
|
|
anthrax toxin receptor 1
| |
Aliases
for ANTXR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Anthrax Toxin Receptor 11 2 | | FLJ106011 | | ATR1 2 3 5 | | FLJ217761 | | TEM81 2 3 5 | | 2310008J16Rik2 | | Tumor Endothelial Marker 82 3 | | 2810405N18Rik2 |
Export aliases for ANTXR1 gene to outside databasesPrevious GC identifers: GC02P069198 GC02P069215 GC02P068977 |
Summaries
for ANTXR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ANTXR1:
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated incolorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracistoxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of thetripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Onceinside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normalcellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.(provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: ANTR1_HUMAN, Q9H6X2Function: Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with theactin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actincytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical veinendothelial cells
 summary
for ANTXR1: ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related
kinases that are activated by DNA damage. These serine-threonine protein kinases are part of the
phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding
proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by
phosphorylating a number of key proteins. Once activated, the checkpoint leads to cell cycle arrest and
either DNA repair or apoptosis. ATM is activated by double stranded breaks and phosphorylates Chk2, whilst
ATR is activated by single strand breaks and phosphorylates Chk1.
Gene Wiki entry for ANTXR1
|
Genomic Views
for ANTXR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANTXR1 gene promoter:
Elk-1 POU2F1 p53 POU2F1a FOXD1 STAT5A LCR-F1 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANTXR1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANTXR1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p13.1 Ensembl cytogenetic band: 2p13.3 HGNC cytogenetic band: 2p13.1ANTXR1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P069152: view genomic region
(about GC identifiers)
Start:
|
69,240,276 bp from pter |
End:
|
69,476,459 bp from pter |
Size:
|
236,184 bases |
Orientation:
|
plus strand |
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Proteins
for ANTXR1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANTR1_HUMAN, Q9H6X2 (See
protein sequence)Recommended Name: Anthrax toxin receptor 1 precursor Size: 564 amino acids; 62789 Da
Subunit: Interacts with gelatin and type 1 collagen. Interacts with the actin cytoskeleton. Binds to the protectiveantigen (PA) of Bacillus anthracis. Binding does not occur in the presence of calcium
Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane;Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein.Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base oflamellipodia
Sequence caution: Sequence=BAA91707.1; Type=Miscellaneous discrepancy; Note=Erroneous initiation (TranslationN-terminally extended) due to a conflict with the genome, including a frameshift; Sequence=BAB15128.1; Type=Erroneousinitiation; Note=Translation N-terminally extended;
1 PDB 3D structure from  and Proteopedia  for ANTXR1:3N2N (3D)
Secondary accessions: A8K7U8 Q4ZFV6 Q53QD8 Q96P02 Q9NVP3Alternative splicing: 4 isoforms: Q9H6X2-1 Q9H6X2-2 Q9H6X2-3 Q9H6X2-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ANTXR1: NX_Q9H6X2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H6X2
ANTXR1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_060623.2 NP_115584.1 NP_444262.1
ENSEMBL proteins: ENSP00000301945 ENSP00000387058 ENSP00000386494 ENSP00000430776
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
ANTXR1 for ontologies About GeneDecksing
ANTXR1 Antibody Products:
Assay Products for ANTXR1: |
Protein
Domains /
Families
for ANTXR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANTXR1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H6X2ProtoNet protein and cluster: Q9H6X2 2 Blocks protein families: IPB002035 Von Willebrand factor type A domain signature IPB008399 Anthrax receptor
UniProtKB/Swiss-Prot: ANTR1_HUMAN, Q9H6X2Domain: Binding to PA occurs through the VWA domainSimilarity: Belongs to the ATR familySimilarity: Contains 1 VWFA domain |
Function
for ANTXR1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ANTR1_HUMAN, Q9H6X2Function: Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with theactin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actincytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical veinendothelial cellsInduction: Up-regulated in cultured angiogenic umbilical vein endothelial cells
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXR1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXR1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ANTXR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANTXR1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANTXR1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
ANTXR1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ANTXR1:
Animal Models:
Mouse knock-outs for ANTXR1: Antxr1tm1.2Bstc Antxr1tm1.2Lepp
11 MGI mutant phenotypes (inferred from 7 alleles ) (MGI details for Antxr1):
ANTXR1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ANTXR1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cellular roles of Anthrax toxin | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Tocris Bioscience Pathway for ANTXR1
1  BioSystems Pathway for ANTXR1
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANTXR1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/9 Interacting proteins for ANTXR1 (Q9H6X21, 3 ENSP000003019454) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
ANTXR1 for ontologies About GeneDecksing
|
Drugs & Compounds
for ANTXR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for ANTXR1 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| CGK 733 | Selective inhibitor of ATR and ATM kinases | [905973-89-9] |
1 HMDB Compound for ANTXR1 About this table
Search CenterWatch for drugs/clinical trials and news about ANTXR1 / ANTR1
|
Transcripts
for ANTXR1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANTXR1 gene (3 alternative transcripts): NM_018153.3 NM_032208.2 NM_053034.2 Unigene Cluster for ANTXR1: Anthrax toxin receptor 1 Hs.165859 [show with all ESTs]Unigene Representative Sequence: NM_0322087 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000303714(uc002sff.3 uc002sfg.3) ENST00000409829(uc002sfe.3)
ENST00000463335(uc002sfd.2) ENST00000409349 ENST00000482235 ENST00000481119
ENST00000497197
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXR1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXR1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ANTXR1 (NM_032208) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANTXR1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANTXR1 |
Additional cDNA sequence: AF090095.1 AF279145.2 AF421380.1 AK002160.1 AK025429.1 AK126783.1 AK223273.1 AK292113.1 AK309553.1 AL110155.1 BC012074.1 BC012475.1 JX424838.1 JX424839.1 23 DOTS entries: DT.100030836 DT.119004 DT.97775779 DT.101968313 DT.120969172 DT.309596 DT.120969196 DT.120969200 DT.100821866 DT.101976518 DT.100030845 DT.100821863 DT.120969213 DT.75107758 DT.95278535 DT.120969167 DT.120969219 DT.421219 DT.75179577 DT.91671089 DT.95125892 DT.100821867 DT.91726528 24/346 AceView cDNA sequences (see all 346): BU687536 CB215475 BX474676 AW515125 CN483575 AI400227 CB149116 AW296332 CA434543 BM472775 T30707 BI092860 CA407229 AF421380 CA448221 Z39069 CA447761 AI277545 BU736182 BM698431 BM666135 AW118038 BU685479 BM980681
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ANTXR1 (see all 7) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | - | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 21 |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for ANTXR1
|
Expression
for ANTXR1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANTXR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTATAGGAGA
About this image
See ANTXR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANTXR1
SOURCE GeneReport for Unigene cluster: Hs.165859
UniProtKB/Swiss-Prot: ANTR1_HUMAN, Q9H6X2Tissue specificity: Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumorendothelial cells
SABiosciences Expression via Pathway-Focused PCR Array including ANTXR1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANTXR1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANTXR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANTXR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANTXR1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANTXR1 |
Orthologs
for ANTXR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ANTXR1 gene from 2/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ANTXR11 |
anthrax toxin receptor 1 |
79.67(n)
88.45(a) |
|
428199 XM_425758.3 XP_425758.3 |
zebrafish
(Danio rerio) |
Actinopterygii |
BI867612.12 |
-- |
76.91(n) |
|
BI867612.1 |
ENSEMBL Gene Tree for ANTXR1 (if available)
TreeFam Gene Tree for ANTXR1 (if available) |
Paralogs
for ANTXR1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANTXR1 gene
- ANTXRL2 ANTXR22
3 SIMAP similar genes for ANTXR1 using alignment to 6 protein entries: ANTR1_HUMAN (see all proteins):ANTXR1/NNG1 fusion ANTXR2 ANTXRL
ANTXR1 for paralogs About GeneDecksing
|
Genomic Variants
for ANTXR1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANTXR1 (69240276 - 69476459 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ANTXR1
1 CNV: 7279
Human Gene Mutation Database (HGMD): ANTXR1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANTXR1 |
|
Disorders
/ Diseases
for ANTXR1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANTXR1 for disorders About GeneDecksing
OMIM gene information: 606410
OMIM disorders: 602089
UniProtKB/Swiss-Prot: ANTR1_HUMAN, Q9H6X2
Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI) [MIM:602089]. HCIare benign, highly proliferative lesions involving aberrant localized growth of capillary endothelium. They are themost common tumor of infancy, occurring in up to 10% of all births. Hemangiomas tend to appear shortly after birth andshow rapid neonatal growth for up to 12 months characterized by endothelial hypercellularity and increased numbers ofmast cells. This phase is followed by slow involution at a rate of about 10% per year and replacement by fibrofattystroma
13  diseases for ANTXR1: About MalaCardshemangioma, capillary infantile colorectal cancer inhalation anthrax hemangioma
anthrax disease gingival hypertrophy ataxia telangiectasia synovitis
ataxia gingivitis breast cancer melanoma
neuronitis
1 disease from the University of Copenhagen DISEASES database for ANTXR1:Inhalation anthrax 3 Novoseek disease relationships for ANTXR1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: ANTXR1 (1 document)
Export disorders for ANTXR1 gene to outside databases
|
Publications
for ANTXR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANTXR1 gene, integrated from 9 sources (see all 64):
(articles sorted by number of sources associating them with ANTXR1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genes expressed in human tumor endothelium. (PubMed id 10947988)1, 2, 3 St Croix B....Kinzler K.W. (2000)
- Human capillary morphogenesis protein 2 functions as an anthrax toxin receptor. (PubMed id 12700348)1, 2, 9 Scobie H.M.... Young J.A.T. (2003)
- Identification of the cellular receptor for anthrax toxin. (PubMed id 11700562)1, 2, 9 Bradley K.A.... Young J.A.T. (2001)
- The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin. (PubMed id 20585457)1, 2 Fu S.... Rao Z. (2010)
- Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton. (PubMed id 16762926)1, 2 Werner E.... Faundez V. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- TEM8 expression stimulates endothelial cell adhesion and migration by regulating cell-matrix interactions on collagen. (PubMed id 15777794)1, 2 Hotchkiss K.A....Terman B.I. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for ANTXR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ANTXR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANTXR1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANTXR1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ANTXR1 gene:
Search GeneIP for patents involving ANTXR1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ANTXR1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for ANTXR1 | | OriGene shRNA RFP for ANTXR1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANTXR1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANTXR1 | | | OriGene Protein Over-expression Lysate for ANTXR1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ANTXR1 | | OriGene 3'-UTR Clone for ANTXR1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXR1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANTXR1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ANTXR1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ANTXR1 | | OriGene Custom Protein Services for ANTXR1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANTXR1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANTXR1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANTXR1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANTXR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANTXR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANTXR1 |
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 | | | ANTXR1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANTXR1 |
|  |  |  | | | | ThermoFisher Antibodies for ANTXR1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANTXR1 |
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