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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANO9 Gene

protein-coding   GIFtS: 51
GCID: GC11M000409

Anoctamin 9

(Previous names: tumor protein p53 inducible protein 5, transmembrane protein...)
(Previous symbols: TP53I5, TMEM16J)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Anoctamin 91 2     Tumor Protein P53-Inducible Protein 52 3
Transmembrane Protein 16J1 2 3     PIG52 3
TMEM16J1 2 3     P53-Induced Gene 5 Protein2 3
TP53I51 2 3     anoctamin-92
Tumor Protein P53 Inducible Protein 51 2     

External Ids:    HGNC: 206791   Entrez Gene: 3384402   Ensembl: ENSG000001851017   UniProtKB: A1A5B43   

Export aliases for ANO9 gene to outside databases

Previous GC identifer: GC11M000233


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ANO9 Gene: 
ANO9 (anoctamin 9) is a protein-coding gene. Diseases associated with ANO9 include tuberculosis, and among its related super-pathways are Stimuli-sensing channels and SLC-mediated transmembrane transport. GO annotations related to this gene include intracellular calcium activated chloride channel activity. An important paralog of this gene is ANO6.

UniProtKB/Swiss-Prot: ANO9_HUMAN, A1A5B4
Function: Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANO9 gene promoter:
         Spz1   AML1a   HNF-4alpha2   Cdc5   HNF-4alpha1   Egr-2   AREB6   PPAR-gamma1   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANO9 promoter sequence
   Search SABiosciences Chromatin IP Primers for ANO9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANO9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

ANO9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANO9 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M000409:  view genomic region     (about GC identifiers)

Start:
417,930 bp from pter      End:
442,011 bp from pter
Size:
24,082 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANO9_HUMAN, A1A5B4 (See protein sequence)
Recommended Name: Anoctamin-9  
Size: 782 amino acids; 90367 Da
Subcellular location: Cell membrane; Multi-pass membrane protein. Note=Shows predominantly an intracellular
localization with a weak expression in the cell membrane
Miscellaneous: The term 'anoctamin' was coined because these channels are anion selective and have eight (OCT)
transmembrane segments. There is some dissatisfaction in the field with the Ano nomenclature because it is not
certain that all the members of this family are anion channels or have the 8-transmembrane topology
Sequence caution: Sequence=BAB84914.1; Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: B3KUC4 B4E134 Q8TEN4
Alternative splicing: 3 isoforms:  A1A5B4-1   A1A5B4-2   A1A5B4-3   

Explore the universe of human proteins at neXtProt for ANO9: NX_A1A5B4

Explore proteomics data for ANO9 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A1A5B4

  • ANO9 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANO9 Protein Expression
    REFSEQ proteins: NP_001012302.2  
    ENSEMBL proteins: 
     ENSP00000332788  
    Reactome Protein details: A1A5B4
    Human Recombinant Protein Products for ANO9: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ANO9 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    ANO9 for ontologies           About GeneDecksing



    ANO9 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for ANO9


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANO: Ion channels / Chloride channels : Calcium activated : Anoctamins

    1 InterPro protein domain:
     IPR007632 Anoctamin

    Graphical View of Domain Structure for InterPro Entry A1A5B4

    ProtoNet protein and cluster: A1A5B4

    UniProtKB/Swiss-Prot: ANO9_HUMAN, A1A5B4
    Similarity: Belongs to the anoctamin family


    ANO9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANO9_HUMAN, A1A5B4
    Function: Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005229NOT intracellular calcium activated chloride channel activity IDA--
         
    ANO9 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANO9 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ANO9

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANO9 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ANO9 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANO9
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ANO9
    SwitchGear 3'UTR luciferase reporter plasmidANO9 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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                         Customized lentivirus expression plasmids for stable overexpression of ANO9 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANO9


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ANO9 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ion channel transport
    Ion channel transport0.49
    Stimuli-sensing channels0.49
    2SLC-mediated transmembrane transport
    Transmembrane transport of small molecules0.50

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for ANO9
        Transmembrane transport of small molecules
    Stimuli-sensing channels
    Ion channel transport



    ANO9 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANO9

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ANO9 (ENSP000003327884) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DLG1ENSP000003457314STRING: ENSP00000345731
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034220ion transmembrane transport TAS--
    GO:0055085transmembrane transport TAS--

    ANO9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANO9

    2 HMDB Compounds for ANO9    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    ChlorineCl2 (see all 13)16887-00-6--

    Search CenterWatch for drugs/clinical trials and news about ANO9

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANO9 gene: 
    NM_001012302.2  

    Unigene Cluster for ANO9:

    Anoctamin 9
    Hs.501622  [show with all ESTs]
    Unigene Representative Sequence: NM_001012302
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000526142 ENST00000534161(uc001lph.2) ENST00000532094(uc001lpi.2 uc010qvv.1)
    ENST00000528927 ENST00000332826 ENST00000524802 ENST00000525804 ENST00000525857

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ANO9
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ANO9
    SwitchGear 3'UTR luciferase reporter plasmidANO9 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ANO9
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANO9
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    GenScript: all cDNA clones in your preferred vector: ANO9 (NM_001012302)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANO9
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANO9
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                         Customized lentivirus expression plasmids for stable overexpression of ANO9 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANO9
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANO9

    Additional mRNA sequence: 

    AK026923.1 AK096874.1 AK303642.1 AK316479.1 BC047946.1 BC128557.1 BC144415.1 U33271.1 

    10 DOTS entries:

    DT.100758133  DT.208422  DT.100020944  DT.95342153  DT.95084413  DT.120739674  DT.95358143  DT.100721400 
    DT.120739692  DT.91962126 

    24/63 AceView cDNA sequences (see all 63):

    AI826039 BM834800 AI739306 BU729166 CB141922 AA909821 AI697244 BX105541 
    AK096874 AI797426 AK026923 AI246657 AL832289 AI720845 AI283197 AW341433 
    BX415162 AI281218 AI346321 AK074088 BM562371 AA428446 AI222741 AI361787 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ANO9 (see all 11)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18a ·
    SP1:                                -                                                     -           -                                   -     -               
    SP2:                                                                                      -                                               -     -               
    SP3:                                                                                                  -                                   -     -               
    SP4:                                                                                                                          -           -     -               
    SP5:                                                                                      -                                                                     

    ExUns: 18b · 18c ^ 19a · 19b ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24a · 24b
    SP1:        -                             -                           
    SP2:        -                             -                           
    SP3:        -                             -                           
    SP4:        -                                                         
    SP5:                                                                  


    ECgene alternative splicing isoforms for ANO9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANO9 expression in normal human tissues (normalized intensities)      ANO9 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGGGCCGCA
    ANO9 Expression
    About this image


    ANO9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Liver (Hepatobiliary System)
             Mature Mesothelial Cells Hepatic Mesenchyme
     
     Bone (Muscoskeletal System)
             Osteochondro Mesenchymal Cells Thoracic Rib
     
     Cartilage (Muscoskeletal System)
             Osteochondro Mesenchymal Cells Thoracic Rib
     
     Somite (Muscoskeletal System)
             Thoracic Mesenchymal Sclerotome
     
     Thymus (Hematopoietic System)

    See ANO9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANO9

    SOURCE GeneReport for Unigene cluster: Hs.501622
        SABiosciences Custom PCR Arrays for ANO9
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANO9
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANO9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ANO9 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ano91 , 5 anoctamin 91, 5 77.61(n)1
    74.22(a)1
      7 (86.37 cM)5
    713451  NM_178381.31  NP_848468.21 
     1411012195 
    chicken
    (Gallus gallus)
    Aves ANO96
    anoctamin 9
    58(a)
    1 ↔ 1
    5(1537037-1551688)
    lizard
    (Anolis carolinensis)
    Reptilia ANO96
    anoctamin 9
    54(a)
    1 ↔ 1
    1(76408205-76467483)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5598091 anoctamin-9-like 54.95(n)
    46.62(a)
      559809  XM_001922625.3  XP_001922660.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG69386
    --
    21(a)
    1 → many
    3L(11978006-11983605)


    ENSEMBL Gene Tree for ANO9 (if available)
    TreeFam Gene Tree for ANO9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANO9 gene
    ANO62  ANO22  ANO12  ANO52  ANO102  ANO32  ANO42  ANO82  
    ANO72  
    7 SIMAP similar genes for ANO9 using alignment to 1 protein entry:     ANO9_HUMAN:
    ANO4    ANO3    ANO7    ANO2    ANO5    ANO6
    ANO1

    ANO9 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/867 SNPs in ANO9 are shown (see all 867)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0546214
    ----see VAR_0546212 F L mis40--------
    rs1415957501,2
    --382412(+) CAGCCC/TGCTCA 1 -- us2k10--------
    rs1860345381,2
    C,F--419557(+) CAGGGG/ATCTCC 1 -- int11Minor allele frequency- A:0.01EU 1255
    rs1388654751,2
    C--419605(+) TCTTTC/TAGGCA 2 L syn10--------
    rs2017479381,2
    --419643(+) TCGGGC/GGATGA 2 P A mis10--------
    rs734025081,2
    C,F--419650(+) ATGAAC/TTCAGA 2 E syn15Minor allele frequency- T:0.01WA NA 5086
    rs2012870621,2
    C--419683(+) TTGGCA/TATGAC 2 I syn10--------
    rs2004083571,2
    --419689(+) ATGACC/TGCCAG 2 A syn10--------
    rs1997082191,2
    --419690(+) TGACCA/GCCAGC 2 A V mis10--------
    rs1144053901,2
    C,F--419706(+) GATGGT/CCTCCA 2 /T /A mis14Minor allele frequency- C:0.02NA EU 6167

    HapMap Linkage Disequilibrium report for ANO9 (417930 - 442011 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/39 variations for ANO9 (see all 39):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv3176CNV Deletion18987735
    esv1030132CNV Deletion17803354
    dgv182e199CNV Deletion23128226
    esv3908CNV Deletion18987735
    esv1003820CNV Deletion20482838
    esv2476569CNV Deletion19546169
    esv1960258CNV Deletion18987734
    esv273658CNV Insertion20981092
    esv270933CNV Insertion20981092
    nsv469923CNV Loss18288195

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ANO9:    About MalaCards
    tuberculosis    


    ANO9 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ANO9
    Human Genome Epidemiology (HuGE) Navigator: ANO9 (1 document)

    Export disorders for ANO9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANO9 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with ANO9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. A model for p53-induced apoptosis. (PubMed id 9305847)1, 3 Polyak K....Vogelstein B. (1997)
    4. Identification and characterization of human TP53I5 and mouse Tp53i5 genes in silico. (PubMed id 15202010)1, 9 Katoh M. and Katoh M. (2004)
    5. Common polymorphisms in the PKP3-SIGIRR-TMEM16J gene r egion are associated with susceptibility to tuberculosis. (PubMed id 22223854)1 Horne D.J....Hawn T.R. (2012)
    6. The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels. (PubMed id 21984732)2 Scudieri P.... Galietta L.J. (2012)
    7. Anoctamins are a family of Ca2+ activated Cl- channels. (PubMed id 22946059)2 Tian Y.... Kunzelmann K. (2012)
    8. The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age. (PubMed id 22302790)2 Winpenny J.P. and Gray M.A. (2012)
    9. CFTR and TMEM16A are separate but functionally related Cl- channels. (PubMed id 22178883)2 Ousingsawat J....Kunzelmann K. (2011)
    10. Anoctamins. (PubMed id 21607626)2 Kunzelmann K.... Schreiber R. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 338440 HGNC: 20679 AceView: TP53I5 Ensembl:ENSG00000185101 euGenes: HUgn338440
    ECgene: ANO9 H-InvDB: ANO9

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANO9 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANO9 gene:
    Search GeneIP for patents involving ANO9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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