Aliases for ANO3 Gene
External Ids for ANO3 Gene
Previous HGNC Symbols for ANO3 Gene
Previous GeneCards Identifiers for ANO3 Gene
GeneCards Summary for ANO3 Gene
ANO3 (Anoctamin 3) is a Protein Coding gene. Diseases associated with ANO3 include dystonia 24 and autosomal dominant cervical dystonia. Among its related pathways are Ion channel transport and Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include intracellular calcium activated chloride channel activity. An important paralog of this gene is ANO5.
UniProtKB/Swiss-Prot for ANO3 Gene
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide. Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity.