External Ids for ANO10 Gene
Previous HGNC Symbols for ANO10 Gene
Previous GeneCards Identifiers for ANO10 Gene
The transmembrane protein encoded by this gene is a member of a family of calcium-activated chloride channels. Defects in this gene may be a cause of autosomal recessive spinocerebellar ataxia-10. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
GeneCards Summary for ANO10 Gene
ANO10 (Anoctamin 10) is a Protein Coding gene. Diseases associated with ANO10 include spinocerebellar ataxia, autosomal recessive 10 and adult-onset autosomal recessive cerebellar ataxia. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. GO annotations related to this gene include intracellular calcium activated chloride channel activity and calcium activated cation channel activity. An important paralog of this gene is ANO5.
UniProtKB/Swiss-Prot for ANO10 Gene
Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.