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Aliases for ANKUB1 Gene

Aliases for ANKUB1 Gene

  • Ankyrin Repeat And Ubiquitin Domain Containing 1 2 3 5
  • Ankyrin Repeat And Ubiquitin Domain-Containing 1 3 4
  • C3orf16 3 4
  • Chromosome 3 Open Reading Frame 16 2
  • Protein ANKUB1 3

External Ids for ANKUB1 Gene

Previous HGNC Symbols for ANKUB1 Gene

  • C3orf16

Previous GeneCards Identifiers for ANKUB1 Gene

  • GC03M149479

Summaries for ANKUB1 Gene

GeneCards Summary for ANKUB1 Gene

ANKUB1 (Ankyrin Repeat And Ubiquitin Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKUB1 Gene

Genomics for ANKUB1 Gene

Regulatory Elements for ANKUB1 Gene

Enhancers for ANKUB1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ANKUB1 on UCSC Golden Path with GeneCards custom track

Promoters for ANKUB1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKUB1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKUB1 Gene

149,760,648 bp from pter
149,968,385 bp from pter
207,738 bases
Minus strand

Genomic View for ANKUB1 Gene

Genes around ANKUB1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKUB1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKUB1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKUB1 Gene

Proteins for ANKUB1 Gene

  • Protein details for ANKUB1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein ANKUB1
    Protein Accession:
    Secondary Accessions:
    • B4E2N8

    Protein attributes for ANKUB1 Gene

    424 amino acids
    Molecular mass:
    47648 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKUB1 Gene


neXtProt entry for ANKUB1 Gene

Post-translational modifications for ANKUB1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKUB1 Gene

No data available for DME Specific Peptides for ANKUB1 Gene

Domains & Families for ANKUB1 Gene

Gene Families for ANKUB1 Gene

Protein Domains for ANKUB1 Gene

Suggested Antigen Peptide Sequences for ANKUB1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANKUB1: view

No data available for UniProtKB/Swiss-Prot for ANKUB1 Gene

Function for ANKUB1 Gene

Animal Model Products

CRISPR Products

miRNA for ANKUB1 Gene

miRTarBase miRNAs that target ANKUB1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKUB1 Gene

Localization for ANKUB1 Gene

Subcellular locations from

Jensen Localization Image for ANKUB1 Gene COMPARTMENTS Subcellular localization image for ANKUB1 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
golgi apparatus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKUB1 Gene

Pathways & Interactions for ANKUB1 Gene

SuperPathways for ANKUB1 Gene

No Data Available

Interacting Proteins for ANKUB1 Gene

Gene Ontology (GO) - Biological Process for ANKUB1 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKUB1 Gene

Drugs & Compounds for ANKUB1 Gene

No Compound Related Data Available

Transcripts for ANKUB1 Gene

mRNA/cDNA for ANKUB1 Gene

(7) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKUB1 Gene

Ankyrin repeat and ubiquitin domain containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKUB1 Gene

No ASD Table

Relevant External Links for ANKUB1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKUB1 Gene

mRNA expression in normal human tissues for ANKUB1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKUB1 Gene

This gene is overexpressed in Cervix - Endocervix (x10.3), Testis (x10.0), and Lung (x4.4).

NURSA nuclear receptor signaling pathways regulating expression of ANKUB1 Gene:


SOURCE GeneReport for Unigene cluster for ANKUB1 Gene:

genes like me logo Genes that share expression patterns with ANKUB1: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ANKUB1 Gene

Orthologs for ANKUB1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKUB1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKUB1 34
  • 87.48 (n)
  • 83.79 (a)
  • 83 (a)
(Canis familiaris)
Mammalia ANKUB1 34
  • 88.77 (n)
  • 84.87 (a)
(Mus musculus)
Mammalia Gm410 34
  • 86.32 (n)
  • 86.84 (a)
Ankub1 16
Gm410 35
  • 86 (a)
(Pan troglodytes)
Mammalia ANKUB1 34
  • 99.45 (n)
  • 99.08 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Ankub1 34
  • 82.1 (n)
  • 78.41 (a)
(Monodelphis domestica)
Mammalia ANKUB1 35
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia ANKUB1 35
  • 73 (a)
(Anolis carolinensis)
Reptilia ANKUB1 35
  • 57 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankub1 34
  • 59.85 (n)
  • 52.61 (a)
Str.19383 34
Species where no ortholog for ANKUB1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKUB1 Gene

Gene Tree for ANKUB1 (if available)
Gene Tree for ANKUB1 (if available)

Paralogs for ANKUB1 Gene

No data available for Paralogs for ANKUB1 Gene

Variants for ANKUB1 Gene

Sequence variations from dbSNP and Humsavar for ANKUB1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs7645720 - 149,768,013(+) GGGCC(A/G)CGCAC intron-variant, reference, missense
rs3821406 - 149,767,744(-) AAAAT(G/T)TCAGT intron-variant, reference, missense
rs7610425 - 149,767,506(+) GCTGC(C/T)TGCAG intron-variant, reference, missense
rs954714 -- 149,761,514(-) ACAGC(A/G)TGTGA downstream-variant-500B, reference, synonymous-codon
rs954715 -- 149,761,469(-) ACAAC(C/T)TCAGT downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ANKUB1 Gene

Variant ID Type Subtype PubMed ID
esv1145264 CNV insertion 17803354
esv34142 CNV loss 18971310
esv3598148 CNV loss 21293372
nsv829754 CNV gain 17160897

Variation tolerance for ANKUB1 Gene

Gene Damage Index Score: 4.99; 68.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKUB1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKUB1 Gene

Disorders for ANKUB1 Gene

Relevant External Links for ANKUB1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKUB1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKUB1 Gene

Publications for ANKUB1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 65
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3 65

Products for ANKUB1 Gene

Sources for ANKUB1 Gene