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Aliases for ANKUB1 Gene

Aliases for ANKUB1 Gene

  • Ankyrin Repeat And Ubiquitin Domain Containing 1 2 3 5
  • C3orf16 3 4
  • Ankyrin Repeat And Ubiquitin Domain-Containing 1 4
  • Chromosome 3 Open Reading Frame 16 2
  • Protein ANKUB1 3

External Ids for ANKUB1 Gene

Previous HGNC Symbols for ANKUB1 Gene

  • C3orf16

Previous GeneCards Identifiers for ANKUB1 Gene

  • GC03M149479

Summaries for ANKUB1 Gene

GeneCards Summary for ANKUB1 Gene

ANKUB1 (Ankyrin Repeat And Ubiquitin Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKUB1 Gene

Genomics for ANKUB1 Gene

Regulatory Elements for ANKUB1 Gene

Enhancers for ANKUB1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G150248 1.4 FANTOM5 Ensembl ENCODE 10.4 -281.0 -281027 2.7 CTCF PKNOX1 SIN3A CEBPG RAD21 ARID3A POLR2A SMC3 MAFK GATAD2A PFN2 ANKUB1 ENSG00000242791 ENSG00000278234 LOC105374154
GH03G150183 1.2 Ensembl ENCODE 11.7 -216.0 -215964 1.3 FOXA2 WRNIP1 ARID4B ZNF48 RAD21 SLC30A9 GATA2 EGR1 ZNF366 ZNF143 PFN2 ENSG00000242791 ANKUB1 GC03P150194 RPL32P9
GH03G150093 1.3 ENCODE dbSUPER 10.6 -126.2 -126150 1.6 HDGF PKNOX1 AGO1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 FOS SNRPCP3 LOC730021 PFN2 ENSG00000242791 ANKUB1 MED12L LOC105374313 RPL32P9
GH03G150146 1.3 FANTOM5 Ensembl ENCODE 10.6 -180.1 -180149 4.4 ZNF507 IRF9 ZNF316 CTBP1 NFE2 FOS ZNF740 NR2F1 BHLHE40 MNT PFN2 LINC01998 ENSG00000242791 ANKUB1 RPL32P9 LOC105374313
GH03G150220 1 Ensembl ENCODE 12 -252.8 -252816 0.8 CTCF RB1 ZNF48 RAD21 ZNF316 ZBTB48 ZNF143 SMC3 MAFK DEK PFN2 ENSG00000242791 ANKUB1 TSC22D2 LINC01998 ENSG00000241048 GC03P150194
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ANKUB1 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKUB1 Gene

Chromosome:
3
Start:
149,760,648 bp from pter
End:
149,968,385 bp from pter
Size:
207,738 bases
Orientation:
Minus strand

Genomic View for ANKUB1 Gene

Genes around ANKUB1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKUB1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKUB1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKUB1 Gene

Proteins for ANKUB1 Gene

  • Protein details for ANKUB1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFN9-ANKUB_HUMAN
    Recommended name:
    Protein ANKUB1
    Protein Accession:
    A6NFN9
    Secondary Accessions:
    • B4E2N8

    Protein attributes for ANKUB1 Gene

    Size:
    424 amino acids
    Molecular mass:
    47648 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKUB1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKUB1 Gene

Post-translational modifications for ANKUB1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKUB1 Gene

Domains & Families for ANKUB1 Gene

Gene Families for ANKUB1 Gene

Protein Domains for ANKUB1 Gene

Suggested Antigen Peptide Sequences for ANKUB1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANKUB1: view

No data available for UniProtKB/Swiss-Prot for ANKUB1 Gene

Function for ANKUB1 Gene

Animal Model Products

miRNA for ANKUB1 Gene

miRTarBase miRNAs that target ANKUB1

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKUB1 Gene

Localization for ANKUB1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKUB1 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1
peroxisome 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKUB1 Gene

Pathways & Interactions for ANKUB1 Gene

SuperPathways for ANKUB1 Gene

No Data Available

Interacting Proteins for ANKUB1 Gene

Gene Ontology (GO) - Biological Process for ANKUB1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKUB1 Gene

Drugs & Compounds for ANKUB1 Gene

No Compound Related Data Available

Transcripts for ANKUB1 Gene

mRNA/cDNA for ANKUB1 Gene

(7) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKUB1 Gene

Ankyrin repeat and ubiquitin domain containing 1:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKUB1 Gene

No ASD Table

Relevant External Links for ANKUB1 Gene

GeneLoc Exon Structure for
ANKUB1
ECgene alternative splicing isoforms for
ANKUB1

Expression for ANKUB1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKUB1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKUB1 Gene

This gene is overexpressed in Cervix - Endocervix (x10.3), Testis (x10.0), and Lung (x4.4).

NURSA nuclear receptor signaling pathways regulating expression of ANKUB1 Gene:

ANKUB1

SOURCE GeneReport for Unigene cluster for ANKUB1 Gene:

Hs.665988
genes like me logo Genes that share expression patterns with ANKUB1: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKUB1 Gene

Orthologs for ANKUB1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKUB1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKUB1 34 35
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia ANKUB1 34
  • 88.77 (n)
cow
(Bos Taurus)
Mammalia ANKUB1 34 35
  • 87.48 (n)
mouse
(Mus musculus)
Mammalia Gm410 34 35
  • 86.32 (n)
Ankub1 16
rat
(Rattus norvegicus)
Mammalia Ankub1 34
  • 82.1 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ANKUB1 35
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKUB1 35
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKUB1 35
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankub1 34
  • 59.85 (n)
Str.19383 34
Species where no ortholog for ANKUB1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKUB1 Gene

ENSEMBL:
Gene Tree for ANKUB1 (if available)
TreeFam:
Gene Tree for ANKUB1 (if available)

Paralogs for ANKUB1 Gene

No data available for Paralogs for ANKUB1 Gene

Variants for ANKUB1 Gene

Sequence variations from dbSNP and Humsavar for ANKUB1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000165825 -- 149,765,497(+) GTATA(C/T)AACAA intron-variant
rs1000179838 -- 149,761,212(+) TTTTC(C/T)ATTGT downstream-variant-500B, utr-variant-3-prime
rs1000268318 -- 149,765,533(+) AAAAC(-/CACA)CACAC intron-variant
rs1000413547 -- 149,794,081(+) AGTCA(C/G)CTACT upstream-variant-2KB
rs1000493144 -- 149,766,970(+) GGATT(C/G)GCCAA intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ANKUB1 Gene

Variant ID Type Subtype PubMed ID
esv1145264 CNV insertion 17803354
esv34142 CNV loss 18971310
esv3598148 CNV loss 21293372
nsv829754 CNV gain 17160897

Variation tolerance for ANKUB1 Gene

Gene Damage Index Score: 4.99; 68.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKUB1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKUB1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKUB1 Gene

Disorders for ANKUB1 Gene

Relevant External Links for ANKUB1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKUB1

No disorders were found for ANKUB1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKUB1 Gene

Publications for ANKUB1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3 64

Products for ANKUB1 Gene

Sources for ANKUB1 Gene

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