Aliases for ANKS6 Gene
Aliases for ANKS6 Gene
External Ids for ANKS6 Gene
- HGNC: 26724
- Entrez Gene: 203286
- Ensembl: ENSG00000165138
- OMIM: 615370
- UniProtKB: Q68DC2
Previous HGNC Symbols for ANKS6 Gene
- SAMD6
- ANKRD14
Previous GeneCards Identifiers for ANKS6 Gene
- GC09M100533
- GC09M101493
- GC09M071093
Summaries for ANKS6 Gene
-
This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. [provided by RefSeq, Jul 2015]
GeneCards Summary for ANKS6 Gene
ANKS6 (Ankyrin Repeat And Sterile Alpha Motif Domain Containing 6) is a Protein Coding gene. Diseases associated with ANKS6 include Nephronophthisis 16 and Nephronophthisis 2, Infantile. GO annotations related to this gene include protein homodimerization activity. An important paralog of this gene is KIDINS220.
UniProtKB/Swiss-Prot for ANKS6 Gene
-
Required for renal function.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKS6 Gene
Genomics for ANKS6 Gene
Regulatory Elements for ANKS6 Gene
Enhancers for ANKS6 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH09G098806 | 1.6 | FANTOM5 Ensembl ENCODE | 14.6 | -12.2 | -12198 | 5.1 | ATF1 PKNOX1 FEZF1 TCF12 ZNF121 GLIS2 FOS KDM4B SP3 MYNN | ANKS6 GALNT12 GC09P098862 |
| GH09G098790 | 1.5 | Ensembl ENCODE dbSUPER | 12.7 | +5.4 | 5413 | 1.8 | SIN3A ZNF2 ZNF143 FOS KLF13 DEK SP3 REST SMARCB1 ZNF592 | ANKS6 GABBR2 |
| GH09G098777 | 1 | ENCODE dbSUPER | 14.7 | +15.5 | 15499 | 7.5 | BCOR KLF1 ZMYM3 E2F1 ZNF316 POLR2A RCOR1 NR2F6 NFE2 MAFK | ANKS6 GABBR2 |
| GH09G098795 | 0.9 | ENCODE | 12.1 | +0.6 | 597 | 1.6 | HDGF SIN3A ZNF766 ELK1 ZNF143 ZNF592 SREBF1 CREB3 KDM1A CTCF | ANKS6 GABBR2 |
| GH09G098805 | 0.9 | Ensembl ENCODE | 11.9 | -8.9 | -8888 | 0.9 | CTCF HLF CEBPB DPF2 CEBPG ZFHX2 GATA3 PBX2 SMC3 FOS | ANKS6 GALNT12 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ANKS6 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ANKS6 gene promoter:
Regulatory Element Products
Genomic Location for ANKS6 Gene
- Chromosome:
- 9
- Start:
- 98,731,329 bp from pter
- End:
- 98,796,965 bp from pter
- Size:
- 65,637 bases
- Orientation:
- Minus strand
Genomic View for ANKS6 Gene
Genes around ANKS6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q22.33 by Ensembl
- 9q22.33 by Entrez Gene
- 9q22.33 by HGNC
ANKS6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ANKS6 Gene
Proteins for ANKS6 Gene
-
Protein details for ANKS6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q68DC2-ANKS6_HUMAN
- Recommended name:
- Ankyrin repeat and SAM domain-containing protein 6
- Protein Accession:
- Q68DC2
- A0SE62
- Q5VSL0
- Q5VSL2
- Q5VSL3
- Q5VSL4
- Q68DB8
- Q6P2R2
- Q8N9L6
- Q96D62
Protein attributes for ANKS6 Gene
- Size:
- 871 amino acids
- Molecular mass:
- 92219 Da
- Quaternary structure:
-
- Homooligomer (By similarity). Central component of a complex containing at least ANKS6, INVS, NEK8 and NPHP3. ANKS6 may organize complex assembly by linking INVS and NPHP3 to NEK8 and INVS may target the complex to the proximal ciliary axoneme (PubMed:23793029). Interacts (via SAM domain) with BICC1 (via KH domains) in an RNA-dependent manner (By similarity). Interacts with ANKS3 (PubMed:24998259).
- SequenceCaution:
-
- Sequence=AAH64367.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC04317.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAH18298.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAH69985.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAH69986.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAH71295.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAH71296.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for ANKS6 Gene
Post-translational modifications for ANKS6 Gene
- Hydroxylated at Asn-138, most probably by HIF1AN. This hydroxylation results in decreased NEK8-binding.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for ANKS6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ANKS6
-
Abcam antibodies for ANKS6
- Invitrogen Antibodies for ANKS6
- antibodies-online Antibodies for ANKS6: See all 19
- Search GeneTex for Antibodies for ANKS6
-
Santa Cruz Biotechnology (SCBT) Antibodies for ANKS6
Protein Products
-
OriGene Purified Proteins for ANKS6
- Search Origene for MassSpec and Protein Over-expression Lysates for ANKS6
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- Novus Biologicals proteins for ANKS6
- Search GeneTex for Proteins for ANKS6
-
Abcam proteins for ANKS6
Assay Products
No data available for DME Specific Peptides for ANKS6 Gene
Domains & Families for ANKS6 Gene
Gene Families for ANKS6 Gene
Protein Domains for ANKS6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ANKS6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q68DC2UniProtKB/Swiss-Prot:
ANKS6_HUMAN :- The ankyrin repeats are necessary and sufficient for NEK8-binding.
- Domain:
-
- The ankyrin repeats are necessary and sufficient for NEK8-binding.
- The SAM domain mediates interaction with the SAM domain of ANKS3.
Function for ANKS6 Gene
Molecular function for ANKS6 Gene
- UniProtKB/Swiss-Prot Function:
- Required for renal function.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 24998259 |
Phenotypes for ANKS6 Gene
- MGI mutant phenotypes for ANKS6:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ANKS6:
Animal Models for ANKS6 Gene
- MGI Knock Outs for ANKS6:
-
- Anks6 tm1b(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANKS6
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ANKS6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKS6 gene
- Search ViGene Biosciences for ANKS6
CRISPR Products
-
OriGene CRISPR knockouts for ANKS6
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANKS6
- GenScript: Design CRISPR guide RNA sequences for ANKS6
miRNA for ANKS6 Gene
- miRTarBase miRNAs that target ANKS6
-
- hsa-mir-124-3p (MIRT022581)
- hsa-mir-8055 (MIRT645453)
- hsa-mir-1304-5p (MIRT645454)
- hsa-mir-6858-5p (MIRT645455)
- hsa-mir-4689 (MIRT645456)
- hsa-mir-1224-5p (MIRT645457)
- hsa-mir-3915 (MIRT645458)
- hsa-mir-3928-3p (MIRT645459)
- hsa-mir-3938 (MIRT645460)
- hsa-mir-4801 (MIRT645461)
- hsa-mir-4731-3p (MIRT645462)
miRNA Products
- Search ViGene Biosciences for ANKS6
Inhibitory RNA Products
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-
ViGene Biosciences ready-to-package AAV shRNAs for ANKS6 gene
Clone Products
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- VectorBuilder custom plasmid, inducible vectors for ANKS6
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ANKS6
-
ViGene Biosciences adenoviral particle packaged cDNA for ANKS6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ANKS6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKS6 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ANKS6 Gene
Localization for ANKS6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ANKS6 Gene
- Cell projection, cilium. Cytoplasm. Note=Localizes to the proximal region of the primary cilium in the presence of INVS. {ECO:0000250 UniProtKB:Q6GQX6}.
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005929 | cilium | IEA | -- |
| GO:0042995 | cell projection | IEA | -- |
Pathways & Interactions for ANKS6 Gene
No Data Available
Interacting Proteins for ANKS6 Gene
Selected Interacting proteins:
ENSP00000297837
Q68DC2-ANKS6_HUMAN
for ANKS6 Gene via
STRING
MINT
IID
No data available for Pathways by source and SIGNOR curated interactions for ANKS6 Gene
Transcripts for ANKS6 Gene
mRNA/cDNA for ANKS6 Gene
- (9) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (132) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ANKS6 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ANKS6
-
Santa Cruz Biotechnology (SCBT) CRISPR for ANKS6
- GenScript: Design CRISPR guide RNA sequences for ANKS6
miRNA Products
- Search ViGene Biosciences for ANKS6
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ANKS6
- Browse OriGene Inhibitory RNA Products For ANKS6
-
ViGene Biosciences ready-to-package AAV shRNAs for ANKS6 gene
Clone Products
-
OriGene ORF clones in human for ANKS6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ANKS6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKS6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14a | · | 14b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||
| SP5: | - |
Expression for ANKS6 Gene
mRNA differential expression in normal tissues according to GTEx for ANKS6 Gene
This gene is overexpressed in Brain - Cerebellum (x4.5) and Brain - Cerebellar Hemisphere (x4.2).
This gene is overexpressed in Serum (68.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ANKS6 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ANKS6 Gene:
ANKS6SOURCE GeneReport for Unigene cluster for ANKS6 Gene:
Hs.406890Evidence on tissue expression from TISSUES for ANKS6 Gene
- Nervous system(4.4)
- Skin(4.1)
- Kidney(2.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKS6 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- integumentary
- nervous
- urinary
Organs:
Head and neck:
- eye
- head
- mouth
Abdomen:
- abdominal wall
- biliary tract
- gallbladder
- kidney
- liver
- pancreas
Pelvis:
- ureter
- urinary bladder
General:
- skin
Primer Products
-
OriGene qPCR primer pairs for ANKS6
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ANKS6 Gene
Orthologs for ANKS6 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ANKS6 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ANKS6 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ANKS6 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Anks6 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Anks6 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ANKS6 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ANKS6 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ANKS6 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ANKS6 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | anks6 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.13422 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | si:dkey-145p14.5 35 |
|
ManyToMany | |
| fruit fly (Drosophila melanogaster) |
Insecta | CG42534 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | nphp-2 35 |
|
OneToMany |
- Species where no ortholog for ANKS6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ANKS6 Gene
(5) SIMAP similar genes for ANKS6 Gene using alignment to 4 proteins:
Variants for ANKS6 Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs377750405 | Pathogenic, Nephronophthisis 16 (NPHP16) [MIM:615382] | 98,780,235(+) | AGGGC(C/T)GTCGG | nc-transcript-variant, reference, missense | |
| VAR_070106 | Nephronophthisis 16 (NPHP16) [MIM:615382] | ||||
| rs397514257 | Pathogenic | 98,768,253(+) | CACCT(C/G)AGGAA | intron-variant | |
| rs397514258 | Pathogenic | 98,736,625(-) | TCCAC(A/C)GGGAC | splice-acceptor-variant | |
| rs587777024 | Pathogenic | 98,768,159(+) | ACAGG(-/GCTTGACCGAT)GGCTG | nc-transcript-variant, reference, frameshift-variant |
Residual Variation Intolerance Score:
56.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.33;
53.50% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ANKS6 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKS6 Gene
Disorders for ANKS6 Gene
(7) MalaCards diseases for ANKS6 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| nephronophthisis 16 |
|
|
| nephronophthisis 2, infantile |
|
|
| nephronophthisis 4 |
|
|
| nephronophthisis |
|
|
| interstitial nephritis |
|
|
Search ANKS6 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ANKS6_HUMAN- Nephronophthisis 16 (NPHP16) [MIM:615382]: A form of nephronophthisis, a chronic tubulo-interstitial nephritis that progresses to end-stage renal failure. Some patients have cystic kidneys of normal size and no extrarenal manifestations, whereas others have enlarged renal size and severe extrarenal defects, including hypertrophic obstructive cardiomyopathy, aortic stenosis, pulmonary stenosis, patent ductus arteriosus, situs inversus, and periportal liver fibrosis. {ECO:0000269 PubMed:23793029}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for ANKS6
No data available for Genatlas for ANKS6 Gene
Publications for ANKS6 Gene
- ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. (PMID: 23793029) Hoff S. … Lienkamp S.S. (Nat. Genet. 2013) 2 3 4 64
- Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3. (PMID: 24998259) Leettola C.N. … Bowie J.U. (BMC Struct. Biol. 2014) 3 4 64
- Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat. (PMID: 18434273) Kaisaki P.J. … Bihoreau M.T. (Eur J Med Genet 2008) 3 4 64
- Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PMID: 18978678) Vieira A.R. … Marazita M.L. (Genet. Med. 2008) 3 46 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
Products for ANKS6 Gene
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- Novus Biologicals Antibodies for ANKS6
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- Abcam proteins for ANKS6
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- ViGene Biosciences adenoviral particle packaged cDNA for ANKS6 gene
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- Santa Cruz Biotechnology (SCBT) Antibodies for ANKS6
- Search Santa Cruz Biotechnology (SCBT) for ANKS6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ANKS6
- Horizon Cell Lines for ANKS6
- Cyagen custom Knockout/knockin (KOKI) mouse models for ANKS6
- VectorBuilder custom plasmid, inducible vectors for ANKS6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ANKS6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ANKS6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
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