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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ANKS1A Gene

protein-coding   GIFtS: 54
GCID: GC06P034857

Ankyrin Repeat And Sterile Alpha Motif Domain Containing...

(Previous names: ankyrin repeat and SAM domain containing 1, ankyrin repeat...)
(Previous symbol: ANKS1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1A1 2     KIAA02293 5
ANKS11 2 3 5     ODIN3 5
Ankyrin Repeat And SAM Domain Containing 11 2     Ankyrin Repeat And Sterile Alpha Motif Domain Containing 11
Odin2 3     Ankyrin Repeat And SAM Domain-Containing Protein 1A2

External Ids:    HGNC: 209611   Entrez Gene: 232942   Ensembl: ENSG000000649997   OMIM: 6089945   UniProtKB: Q926253   

Export aliases for ANKS1A gene to outside databases

Previous GC identifers: GC06P034966 GC06P034579


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ANKS1A Gene: 
ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) is a protein-coding gene. Diseases associated with ANKS1A include adjustment disorder, and gigantism. GO annotations related to this gene include ephrin receptor binding. An important paralog of this gene is CASKIN1.

UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625
Function: Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control
cell migration and neurite retraction (By similarity)

Gene Wiki entry for ANKS1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ANKS1A gene promoter:
         SRF   POU3F1   SRF (504 AA)   LCR-F1   MZF-1   HEN1   Max   HOXA5   STAT3   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKS1A promoter sequence
   Search SABiosciences Chromatin IP Primers for ANKS1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKS1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

ANKS1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKS1A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P034857:  view genomic region     (about GC identifiers)

Start:
34,857,038 bp from pter      End:
35,059,190 bp from pter
Size:
202,153 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625 (See protein sequence)
Recommended Name: Ankyrin repeat and SAM domain-containing protein 1A  
Size: 1134 amino acids; 123108 Da
Subunit: Interacts with EPHA8; EPHA8 kinase activity-independent but stimulated by EPHA8 ubiquitination (By
similarity). Interacts (via SAM domain) with EPHA2 (via SAM domain)
Subcellular location: Cytoplasm. Cell projection (By similarity). Note=Cytoplasmic before and after growth factor
treatment
Sequence caution: Sequence=BAA13218.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for ANKS1A:
2LMR (3D)    
Secondary accessions: A2RUC1 Q5JYI9 Q5SYR2 Q86WQ7

Explore the universe of human proteins at neXtProt for ANKS1A: NX_Q92625

Explore proteomics data for ANKS1A at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylated on tyrosine residues in response to EGF and PDGF (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92625

  • ANKS1A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ANKS1A Protein Expression
    REFSEQ proteins: NP_056060.2  
    ENSEMBL proteins: 
     ENSP00000353518   ENSP00000438752  

    Human Recombinant Protein Products for ANKS1A: 
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    Cloud-Clone Corp. Proteins for ANKS1A 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0043005neuron projection ISS--

    ANKS1A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing
    SAMD: Sterile alpha motif (SAM) domain containing

    5/7 InterPro protein domains (see all 7):
     IPR013761 SAM/pointed
     IPR001660 SAM
     IPR021129 SAM_type1
     IPR006020 PTyr_interaction_dom
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q92625

    ProtoNet protein and cluster: Q92625

    2 Blocks protein domains:
    IPB001660 Sterile alpha motif SAM
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625
    Similarity: Contains 6 ANK repeats
    Similarity: Contains 1 PID domain
    Similarity: Contains 2 SAM (sterile alpha motif) domains


    ANKS1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANS1A_HUMAN, Q92625
    Function: Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control
    cell migration and neurite retraction (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16273093
    GO:0046875ephrin receptor binding IEA--
         
    ANKS1A for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for ANKS1A:
     G0/1 arrest  Increased G1 DNA content  Increased cell size  Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Anks1):
     normal 

    ANKS1A for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ANKS1A 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANKS1A 
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    SwitchGear 3'UTR luciferase reporter plasmidANKS1A 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKS1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/10 Interacting proteins for ANKS1A (Q926252, 3 ENSP000003535184) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERBB2P046262, 3, ENSP000002695714MINT-74462 MINT-74461 I2D: score=2 STRING: ENSP00000269571
    SFNP319472, 3MINT-3976160 I2D: score=2 
    EGFRP005332, 3, ENSP000002754934MINT-74459 MINT-74460 I2D: score=3 STRING: ENSP00000275493
    YWHAGP619812, 3, ENSP000003063304MINT-50903 I2D: score=4 STRING: ENSP00000306330
    ERBB4Q153032, 3, ENSP000003422354MINT-74463 I2D: score=1 STRING: ENSP00000342235
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006929substrate-dependent cell migration ISS--
    GO:0016322neuron remodeling ISS--
    GO:0048013ephrin receptor signaling pathway ISS--

    ANKS1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ANKS1A (ANS1A)

    Search CenterWatch for drugs/clinical trials and news about ANKS1A / ANS1A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ANKS1A gene: 
    NM_015245.2  

    Unigene Cluster for ANKS1A:

    Ankyrin repeat and sterile alpha motif domain containing 1A
    Hs.656492  [show with all ESTs]
    Unigene Representative Sequence: NM_015245
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000360359(uc003ojx.4 uc011dst.2 uc010jvp.2) ENST00000470698
    ENST00000535627(uc010jvq.1 uc010jvr.1)
    miRNA
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    hsa-miR-4317 hsa-miR-4307 hsa-miR-513a-5p hsa-miR-15a hsa-miR-128 hsa-miR-503 hsa-let-7a-2* hsa-miR-624*
    SwitchGear 3'UTR luciferase reporter plasmidANKS1A 3' UTR sequence
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    Additional mRNA sequence: 

    AK025381.1 AK128362.1 AK298987.1 BC022396.1 BC031934.1 BC132832.1 BC144341.1 D86982.1 
    EF491810.1 

    16 DOTS entries:

    DT.313308  DT.97779414  DT.121388995  DT.91983897  DT.100024916  DT.100730672  DT.40109299  DT.97818250 
    DT.100785609  DT.100785610  DT.121388962  DT.75135867  DT.121388921  DT.121389037  DT.75137450  DT.91961780 

    24/164 AceView cDNA sequences (see all 164):

    BM478411 AA828020 AI380077 AI334108 BE326542 BM789557 AI277403 AI075845 
    CA427971 AI185245 CA389481 BE672327 AI668788 AW197614 AI128077 BU676295 
    AI129453 CR625673 AI193515 BE673280 AI652904 BX111396 AF038251 NM_015245 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ANKS1A    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^
    SP1:                                                                          -     -     -                                                                     
    SP2:              -                                                           -                 -     -                                                         
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            

    ExUns: 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29
    SP1:                                          
    SP2:                    -           -         
    SP3:                    -                     
    SP4:                                          


    ECgene alternative splicing isoforms for ANKS1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ANKS1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANKS1A Expression
    About this image


    See ANKS1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ANKS1A

    SOURCE GeneReport for Unigene cluster: Hs.656492

    UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625
    Tissue specificity: Widely expressed (at protein level)

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ANKS1A gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Anks11 , 5 ankyrin repeat and SAM domain containing 11, 5 85.44(n)1
    88.31(a)1
      17 (14.60 cM)5
    2246501  NM_181413.31  NP_852078.11 
     279093405 
    chicken
    (Gallus gallus)
    Aves ANKS1A1 ankyrin repeat and sterile alpha motif domain containing more 77.43(n)
    82.92(a)
      419898  XM_418023.2  XP_418023.2 
    lizard
    (Anolis carolinensis)
    Reptilia ANKS1A6
    ankyrin repeat and sterile alpha motif domain cont...
    73(a)
    1 ↔ 1
    4(120856305-121046585)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253242 Xenopus laevis transcribed sequence with weak similarity more 75.35(n)    BJ035877.1 
    zebrafish
    (Danio rerio)
    Actinopterygii anks1aa6
    ANKS1A (2 of 2)6
    ankyrin repeat and sterile alpha motif domain cont...
    ankyrin repeat and sterile alpha motif domain cont...
    75(a)
    54(a)
    1 ↔ many
    1 ↔ many
    23(278938-323012)
    6(54348374-54376241)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG111686
    CG43936
    --
    26(a)
    23(a)
    many ↔ many
    many ↔ many
    3R(20743868-20748111)
    3R(19202933-19210499)
    worm
    (Caenorhabditis elegans)
    Secernentea C46H3.36
    C11E4.66
    (see all 3)
    Protein C11E4.6
    (see all 3)
    29(a)
    16(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    X(1226224-1230760)
    X(9610561-9617024)


    ENSEMBL Gene Tree for ANKS1A (if available)
    TreeFam Gene Tree for ANKS1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ANKS1A gene
    CASKIN12  CASKIN22  ANKS1B2  
    5 SIMAP similar genes for ANKS1A using alignment to 4 protein entries:     ANS1A_HUMAN (see all proteins):
    ANKS1B    CASKIN2    PSMD10    IkBa    GABPB1

    ANKS1A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/3825 SNPs in ANKS1A are shown (see all 3825)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs355656721,2
    C--34729124(+) CATAC-/TTTTTT 1 -- int10--------
    rs360687251,2
    C--34857871(+) CTTTAT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1858262061,2
    --34857881(+) TTTTTC/TCCCTC 1 -- int10--------
    rs1901016611,2
    --34857954(+) ACCTCC/TGCCTC 1 -- int10--------
    rs1837468031,2
    --34858060(+) GACGGA/GGTTTC 1 -- int10--------
    rs1881775731,2
    --34858066(+) GTTTCA/CCCATA 1 -- int10--------
    rs93489521,2
    C--34858275(+) TGAACC/TTCATT 1 -- int14Minor allele frequency- T:0.13WA NA EA 360
    rs1500277741,2
    --34858488(+) TAGTGC/TGAGTT 1 -- int10--------
    rs37568571,2
    C--34858578(-) CTAAAT/CGAACT 1 -- int15Minor allele frequency- C:0.21EA WA NA 1656
    rs734215071,2
    C,F--34858707(+) ACCAAC/ACCAGG 1 -- int16Minor allele frequency- A:0.23WA NA CSA 245

    HapMap Linkage Disequilibrium report for ANKS1A (34857038 - 35059190 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ANKS1A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2731910CNV Deletion23290073
    esv2731909CNV Deletion23290073
    nsv5256CNV Insertion18451855
    nsv5257CNV Loss18451855
    nsv508402CNV Loss20534489
    nsv462905CNV Gain19166990
    dgv6831n71CNV Gain21882294
    nsv885797CNV Gain21882294


    Human Gene Mutation Database (HGMD): ANKS1A
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKS1A
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608994    OMIM disorders: --

    7 diseases for ANKS1A:    About MalaCards
    adjustment disorder    gigantism    systemic lupus erythematosus    lupus erythematosus
    alcoholism    colorectal cancer    neuronitis

    1 disease from the University of Copenhagen DISEASES database for ANKS1A:
    Adjustment disorder

    ANKS1A for disorders           About GeneDecksing

    Genetic Association Database (GAD): ANKS1A
    Human Genome Epidemiology (HuGE) Navigator: ANKS1A (7 documents)

    Export disorders for ANKS1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ANKS1A gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with ANKS1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2, 3 Nagase T....Nomura N. (1996)
    2. Solution structure of the first Sam domain of Odin and binding studies with the EphA2 receptor. (PubMed id 22332920)1, 2 Mercurio F.A....Leone M. (2012)
    3. A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. (PubMed id 21529783)1, 4 Heath A.C....Montgomery G.W. (2011)
    4. Large-scale association analysis identifies 13 new su sceptibility loci for coronary artery disease. (PubMed id 21378990)1, 4 Schunkert H....Samani N.J. (2011)
    5. Trait-stratified genome-wide association study identi fies novel and diverse genetic associations with serologic and cytokine phenoty pes in systemic lupus erythematosus. (PubMed id 20659327)1, 4 Kariuki S.N....Niewold T.B. (2010)
    6. The role of height-associated loci identified in geno me wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (2010)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    8. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    9. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (2008)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23294 HGNC: 20961 AceView: ANKS1 Ensembl:ENSG00000064999 euGenes: HUgn23294
    ECgene: ANKS1A H-InvDB: ANKS1A

    (According to HUGE)
    About This Section
    HUGE: KIAA0229

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ANKS1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ANKS1A gene:
    Search GeneIP for patents involving ANKS1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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