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ANKS1A Gene

protein-coding   GIFtS: 56
GCID: GC06P034857

Ankyrin Repeat And Sterile Alpha Motif Domain Containing...

(Previous names: ankyrin repeat and SAM domain containing 1, ankyrin repeat...)
(Previous symbol: ANKS1)
  See ANKS1A-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1A1 2     KIAA02293 5
ANKS11 2 3 5     ODIN3 5
Ankyrin Repeat And SAM Domain Containing 11 2     Ankyrin Repeat And Sterile Alpha Motif Domain Containing 11
Odin2 3     Ankyrin Repeat And SAM Domain-Containing Protein 1A2

External Ids:    HGNC: 209611   Entrez Gene: 232942   Ensembl: ENSG000000649997   OMIM: 6089945   UniProtKB: Q926253   

Export aliases for ANKS1A gene to outside databases

Previous GC identifers: GC06P034966 GC06P034579


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ANKS1A Gene:
ANKS1A (ankyrin repeat and sterile alpha motif domain containing 1A) is a protein-coding gene. Diseases associated with ANKS1A include adjustment disorder. GO annotations related to this gene include ephrin receptor binding. An important paralog of this gene is CASKIN1.

UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625
Function: Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control
cell migration and neurite retraction (By similarity)

Gene Wiki entry for ANKS1A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANKS1A gene promoter:
         SRF   POU3F1   SRF (504 AA)   LCR-F1   MZF-1   HEN1   Max   HOXA5   STAT3   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKS1A promoter sequence
   Search Chromatin IP Primers for ANKS1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKS1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

ANKS1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKS1A gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P034857:  view genomic region     (about GC identifiers)

Start:
34,857,038 bp from pter      End:
35,059,190 bp from pter
Size:
202,153 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625 (See protein sequence)
Recommended Name: Ankyrin repeat and SAM domain-containing protein 1A  
Size: 1134 amino acids; 123108 Da
Subunit: Interacts with EPHA8; EPHA8 kinase activity-independent but stimulated by EPHA8 ubiquitination (By
similarity). Interacts (via SAM domain) with EPHA2 (via SAM domain)
Sequence caution: Sequence=BAA13218.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for ANKS1A:
2LMR (3D)    
Secondary accessions: A2RUC1 Q5JYI9 Q5SYR2 Q86WQ7

Explore the universe of human proteins at neXtProt for ANKS1A: NX_Q92625

Explore proteomics data for ANKS1A at MOPED

Post-translational modifications: 

  • Phosphorylated on tyrosine residues in response to EGF and PDGF (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ANKS1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056060.2  
    ENSEMBL proteins: 
     ENSP00000353518   ENSP00000438752  

    ANKS1A Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ANKS1A

     
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    antibodies-online proteins for ANKS1A (4 products) 

     
    antibodies-online peptides for ANKS1A

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    antibodies-online antibodies for ANKS1A (22 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing
    SAMD: Sterile alpha motif (SAM) domain containing

    Selected InterPro protein domains (see all 7):
     IPR021129 SAM_type1
     IPR011993 PH_like_dom
     IPR002110 Ankyrin_rpt
     IPR013761 SAM/pointed
     IPR001660 SAM

    Graphical View of Domain Structure for InterPro Entry Q92625

    ProtoNet protein and cluster: Q92625

    2 Blocks protein domains:
    IPB001660 Sterile alpha motif SAM
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625
    Similarity: Contains 6 ANK repeats
    Similarity: Contains 1 PID domain
    Similarity: Contains 2 SAM (sterile alpha motif) domains


    Find genes that share domains with ANKS1A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ANS1A_HUMAN, Q92625
    Function: Regulator of different signaling pathways. Regulates EPHA8 receptor tyrosine kinase signaling to control
    cell migration and neurite retraction (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16273093
    GO:0046875ephrin receptor binding IEA--
         
    Find genes that share ontologies with ANKS1A           About GenesLikeMe


    Phenotypes:
         4 GenomeRNAi human phenotypes for ANKS1A:
     G0/1 arrest  Increased G1 DNA content  Increased cell size  Increased gamma-H2AX phosphory 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Anks1):
     normal 

    Find genes that share phenotypes with ANKS1A           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ANKS1A

    miRNA
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    miRTarBase miRNAs that target ANKS1A:
    hsa-mir-92a-3p (MIRT049292)

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    Selected qRT-PCR Assays for microRNAs that regulate ANKS1A (see all 53):
    hsa-miR-4317 hsa-miR-4307 hsa-miR-513a-5p hsa-miR-15a hsa-miR-128 hsa-miR-503 hsa-let-7a-2* hsa-miR-624*
    SwitchGear 3'UTR luciferase reporter plasmidANKS1A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ANKS1A

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ANS1A_HUMAN, Q92625: Cytoplasm. Cell projection (By similarity). Note=Cytoplasmic before and after growth factor
    treatment
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol3

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0043005neuron projection ISS--

    Find genes that share ontologies with ANKS1A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANKS1A
    Interactions:

        Search GeneGlobe Interaction Network for ANKS1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for ANKS1A (Q926251, 2, 3 ENSP000003535184) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ERBB2P046261, 2, 3, ENSP000002695714EBI-1048612,EBI-641062 MINT-74462 MINT-74461 I2D: score=2 STRING: ENSP00000269571
    SFNP319472, 3MINT-3976160 I2D: score=2 
    EGFRP005331, 2, 3, ENSP000002754934EBI-1048612,EBI-297353 MINT-74459 MINT-74460 I2D: score=3 STRING: ENSP00000275493
    YWHAGP619812, 3, ENSP000003063304MINT-50903 I2D: score=4 STRING: ENSP00000306330
    ERBB4Q153032, 3, ENSP000003422354MINT-74463 I2D: score=1 STRING: ENSP00000342235
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006929substrate-dependent cell migration ISS--
    GO:0016322neuron remodeling ISS--
    GO:0048013ephrin receptor signaling pathway ISS--

    Find genes that share ontologies with ANKS1A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANKS1A (ANS1A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ANKS1A gene: 
    NM_015245.2  

    Unigene Cluster for ANKS1A:

    Ankyrin repeat and sterile alpha motif domain containing 1A
    Hs.656492  [show with all ESTs]
    Unigene Representative Sequence: NM_015245
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000360359(uc003ojx.4 uc011dst.2 uc010jvp.2) ENST00000470698
    ENST00000535627(uc010jvq.1 uc010jvr.1)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ANKS1A (see all 53):
    hsa-miR-4317 hsa-miR-4307 hsa-miR-513a-5p hsa-miR-15a hsa-miR-128 hsa-miR-503 hsa-let-7a-2* hsa-miR-624*
    SwitchGear 3'UTR luciferase reporter plasmidANKS1A 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat ANKS1A

    Additional mRNA sequence: 

    AK025381.1 AK128362.1 AK298987.1 BC022396.1 BC031934.1 BC132832.1 BC144341.1 D86982.1 
    EF491810.1 

    16 DOTS entries:

    DT.313308  DT.97779414  DT.121388995  DT.91983897  DT.100024916  DT.100730672  DT.40109299  DT.97818250 
    DT.100785609  DT.100785610  DT.121388962  DT.75135867  DT.121388921  DT.121389037  DT.75137450  DT.91961780 

    Selected AceView cDNA sequences (see all 164):

    BQ220166 BX503283 AI380077 AI918820 BE326542 AF038251 BE672327 D86982 
    AI128077 BX111396 CA437033 BM478411 AI277403 BM789557 CA389481 AI668788 
    CA427971 AI129453 AI652904 AI193515 AF034186 AI185245 BQ705973 BE673280 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ANKS1A    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^
    SP1:                                                                          -     -     -                                                                     
    SP2:              -                                                           -                 -     -                                                         
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            

    ExUns: 24 ^ 25 ^ 26 ^ 27 ^ 28a · 28b ^ 29
    SP1:                                          
    SP2:                    -           -         
    SP3:                    -                     
    SP4:                                          


    ECgene alternative splicing isoforms for ANKS1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANKS1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ANKS1A Expression
    About this image


    ANKS1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Ovary (Reproductive System)
             Oviduct
    ANKS1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANKS1A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656492

    UniProtKB/Swiss-Prot: ANS1A_HUMAN, Q92625
    Tissue specificity: Widely expressed (at protein level)

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKS1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ANKS1A gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Anks11 , 5 ankyrin repeat and SAM domain containing 11, 5 84.72(n)1
    87.41(a)1
      17 (14.60 cM)5
    2246501  NM_001286040.11  NP_001272969.11 
     279093405 
    chicken
    (Gallus gallus)
    Aves ANKS1A1 ankyrin repeat and sterile alpha motif domain containing more 76.93(n)
    82.03(a)
      419898  XM_004935037.1  XP_004935094.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANKS1A6
    ankyrin repeat and sterile alpha motif domain cont...
    73(a)
    1 ↔ 1
    4(120856305-121046585)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.253242 Xenopus laevis transcribed sequence with weak similarity more 75.35(n)    BJ035877.1 
    zebrafish
    (Danio rerio)
    Actinopterygii anks1aa6
    anks1ab6
    ankyrin repeat and sterile alpha motif domain cont...
    ankyrin repeat and sterile alpha motif domain cont...
    74(a)
    52(a)
    1 ↔ many
    1 ↔ many
    23(278923-323012) ENSDARG00000062396
    6(54313687-54377823) ENSDARG00000078901
    fruit fly
    (Drosophila melanogaster)
    Insecta CG111686
    CG43936
    --
    31(a)
    25(a)
    many ↔ many
    many ↔ many
    3R(20743868-20748111)
    3R(19202933-19210499)
    worm
    (Caenorhabditis elegans)
    Secernentea C11E4.66
    Protein C11E4.6 (C11E4.6) mRNA, complete cds
    19(a)
    1 → many
    X(9610563-9617024) WBGene00007520


    ENSEMBL Gene Tree for ANKS1A (if available)
    TreeFam Gene Tree for ANKS1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANKS1A gene
    CASKIN12  CASKIN22  ANKS1B2  
    5 SIMAP similar genes for ANKS1A using alignment to 4 protein entries:     ANS1A_HUMAN (see all proteins):
    ANKS1B    CASKIN2    PSMD10    IkBa    GABPB1

    Find genes that share paralogs with ANKS1A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANKS1A (see all 3825)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs355656721,2
    C--34729124(+) CATAC-/TTTTTT 1 -- int10--------
    rs360687251,2
    C--34857871(+) CTTTAT/-TTTTT 1 -- int11Minor allele frequency- -:0.50NA 2
    rs1858262061,2
    --34857881(+) TTTTTC/TCCCTC 1 -- int10--------
    rs1901016611,2
    --34857954(+) ACCTCC/TGCCTC 1 -- int10--------
    rs1837468031,2
    --34858060(+) GACGGA/GGTTTC 1 -- int10--------
    rs1881775731,2
    --34858066(+) GTTTCA/CCCATA 1 -- int10--------
    rs93489521,2
    C--34858275(+) TGAACC/TTCATT 1 -- int14Minor allele frequency- T:0.13WA NA EA 360
    rs1500277741,2
    --34858488(+) TAGTGC/TGAGTT 1 -- int10--------
    rs37568571,2
    C--34858578(-) CTAAAT/CGAACT 1 -- int15Minor allele frequency- C:0.21EA WA NA 1656
    rs734215071,2
    C,F--34858707(+) ACCAAC/ACCAGG 1 -- int16Minor allele frequency- A:0.23WA NA CSA 245

    HapMap Linkage Disequilibrium report for ANKS1A (34857038 - 35059190 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ANKS1A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2731910CNV Deletion23290073
    esv2731909CNV Deletion23290073
    nsv5256CNV Insertion18451855
    nsv5257CNV Loss18451855
    nsv508402CNV Loss20534489
    nsv462905CNV Gain19166990
    dgv6831n71CNV Gain21882294
    nsv885797CNV Gain21882294

    Human Gene Mutation Database (HGMD): ANKS1A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKS1A
    DNA2.0 Custom Variant and Variant Library Synthesis for ANKS1A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 608994    OMIM disorders: --

    1 disease for ANKS1A:    
    About MalaCards
    adjustment disorder

    1 disease from the University of Copenhagen DISEASES database for ANKS1A:
    Adjustment disorder

    Find genes that share disorders with ANKS1A           About GenesLikeMe

    Genetic Association Database (GAD): ANKS1A
    Human Genome Epidemiology (HuGE) Navigator: ANKS1A (7 documents)

    Export disorders for ANKS1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANKS1A gene, integrated from 10 sources (see all 46):
    (articles sorted by number of sources associating them with ANKS1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2, 3 Nagase T.... Nomura N. (DNA Res. 1996)
    2. Solution structure of the first Sam domain of Odin and binding studies with the EphA2 receptor. (PubMed id 22332920)1, 2 Mercurio F.A....Leone M. (Biochemistry 2012)
    3. A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications. (PubMed id 21529783)1, 4 Heath A.C....Montgomery G.W. (Biol. Psychiatry 2011)
    4. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. (PubMed id 21378990)1, 4 Schunkert H....Samani N.J. (Nat. Genet. 2011)
    5. Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus. (PubMed id 20659327)1, 4 Kariuki S.N....Niewold T.B. (amp 2010)
    6. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (BMC Med. Genet. 2010)
    7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    8. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    9. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (Nat. Genet. 2008)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 23294 HGNC: 20961 AceView: ANKS1 Ensembl:ENSG00000064999 euGenes: HUgn23294
    ECgene: ANKS1A H-InvDB: ANKS1A

    (According to HUGE)
    About This Section

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    HUGE: KIAA0229

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ANKS1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ANKS1A gene:
    Search GeneIP for patents involving ANKS1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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