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Aliases for ANKRD9 Gene

Aliases for ANKRD9 Gene

  • Ankyrin Repeat Domain 9 2 3 5

External Ids for ANKRD9 Gene

Previous GeneCards Identifiers for ANKRD9 Gene

  • GC14M096788
  • GC14M100964
  • GC14M100965
  • GC14M100966
  • GC14M102042
  • GC14M102973
  • GC14M083150

Summaries for ANKRD9 Gene

GeneCards Summary for ANKRD9 Gene

ANKRD9 (Ankyrin Repeat Domain 9) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD9 Gene

Genomics for ANKRD9 Gene

Regulatory Elements for ANKRD9 Gene

Enhancers for ANKRD9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F102507 1.3 FANTOM5 ENCODE 24 -0.1 -60 4.9 ATF1 PKNOX1 ZNF133 ARID4B SIN3A DMAP1 ZNF48 ZNF121 SLC30A9 GLIS2 ANKRD9 RCOR1 CINP TECPR2 ZNF839 AMN LOC105370679
GH14F102522 1.8 FANTOM5 Ensembl ENCODE 15.7 -16.3 -16295 6.2 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF143 RCOR1 TECPR2 RPL23AP11 MOK ANKRD9 TRAF3 DIO3 ENSG00000271780 RNU6-244P DIO3OS
GH14F102530 1.5 FANTOM5 Ensembl ENCODE 17.9 -21.7 -21739 2.7 TBP NFXL1 RFX5 ZNF143 RCOR1 FOS SMARCA5 CEBPB USF2 RCOR2 ANKRD9 RCOR1 TRAF3 MIR4309 LOC105370680
GH14F102479 1 Ensembl ENCODE 24.7 +29.7 29739 1.6 ZNF263 IRF2 NFIA MTA2 CBFB JUNB JUND POLR2A IKZF1 EED ANKRD9 TECPR2 PIR47306 GC14M102433
GH14F102503 1.1 Ensembl ENCODE 18.6 +5.0 5026 2.4 HDAC1 TBL1XR1 KLF17 GLIS2 GATA2 CREM PAF1 ZBTB2 ZBTB11 MBD2 ANKRD9 RCOR1 CINP TECPR2 ZNF839 RNU6-244P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ANKRD9 on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001625371 299 2201 ATF1 PKNOX1 ARID4B DMAP1 ZNF48 ZNF121 SLC30A9 GLIS2 KLF7 KLF13

Genomic Location for ANKRD9 Gene

Chromosome:
14
Start:
102,501,760 bp from pter
End:
102,509,799 bp from pter
Size:
8,040 bases
Orientation:
Minus strand

Genomic View for ANKRD9 Gene

Genes around ANKRD9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD9 Gene

Proteins for ANKRD9 Gene

  • Protein details for ANKRD9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96BM1-ANKR9_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 9
    Protein Accession:
    Q96BM1
    Secondary Accessions:
    • A8K753

    Protein attributes for ANKRD9 Gene

    Size:
    317 amino acids
    Molecular mass:
    34295 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD9 Gene

Post-translational modifications for ANKRD9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD9 Gene

No data available for DME Specific Peptides for ANKRD9 Gene

Domains & Families for ANKRD9 Gene

Gene Families for ANKRD9 Gene

Protein Domains for ANKRD9 Gene

Suggested Antigen Peptide Sequences for ANKRD9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96BM1

UniProtKB/Swiss-Prot:

ANKR9_HUMAN :
  • Contains 3 ANK repeats.
Similarity:
  • Contains 3 ANK repeats.
genes like me logo Genes that share domains with ANKRD9: view

Function for ANKRD9 Gene

genes like me logo Genes that share phenotypes with ANKRD9: view

Animal Models for ANKRD9 Gene

MGI Knock Outs for ANKRD9:

Animal Model Products

  • Taconic Biosciences Mouse Models for ANKRD9

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ANKRD9 Gene

Localization for ANKRD9 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD9 gene
Compartment Confidence
nucleus 2
cytosol 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD9 Gene

Pathways & Interactions for ANKRD9 Gene

SuperPathways for ANKRD9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD9 Gene

Transcripts for ANKRD9 Gene

Unigene Clusters for ANKRD9 Gene

Ankyrin repeat domain 9:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD9 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b
SP1: - -
SP2: - -
SP3: - - - -
SP4:
SP5: -
SP6:

Relevant External Links for ANKRD9 Gene

GeneLoc Exon Structure for
ANKRD9
ECgene alternative splicing isoforms for
ANKRD9

Expression for ANKRD9 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ANKRD9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKRD9 Gene

This gene is overexpressed in Muscle - Skeletal (x6.1) and Heart - Left Ventricle (x4.5).

Protein differential expression in normal tissues from HIPED for ANKRD9 Gene

This gene is overexpressed in Liver, secretome (41.5) and Breast (27.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD9 Gene



Protein tissue co-expression partners for ANKRD9 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD9 Gene:

ANKRD9

SOURCE GeneReport for Unigene cluster for ANKRD9 Gene:

Hs.432945
genes like me logo Genes that share expression patterns with ANKRD9: view

No data available for mRNA Expression by UniProt/SwissProt for ANKRD9 Gene

Orthologs for ANKRD9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD9 34 35
  • 99.16 (n)
cow
(Bos Taurus)
Mammalia ANKRD9 34 35
  • 89.7 (n)
dog
(Canis familiaris)
Mammalia ANKRD9 34 35
  • 89.35 (n)
rat
(Rattus norvegicus)
Mammalia Ankrd9 34
  • 82.17 (n)
mouse
(Mus musculus)
Mammalia Ankrd9 34 16 35
  • 79.64 (n)
oppossum
(Monodelphis domestica)
Mammalia ANKRD9 35
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD9 35
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves ANKRD9 34 35
  • 69.93 (n)
lizard
(Anolis carolinensis)
Reptilia ANKRD9 35
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd9 34
  • 60.36 (n)
zebrafish
(Danio rerio)
Actinopterygii ankrd9 34 35
  • 56.77 (n)
Species where no ortholog for ANKRD9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD9 Gene

ENSEMBL:
Gene Tree for ANKRD9 (if available)
TreeFam:
Gene Tree for ANKRD9 (if available)

Paralogs for ANKRD9 Gene

No data available for Paralogs for ANKRD9 Gene

Variants for ANKRD9 Gene

Sequence variations from dbSNP and Humsavar for ANKRD9 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10138375 -- 102,511,291(+) GACCA(A/G)ACCCC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs10141666 -- 102,503,306(+) tgaga(C/T)ggagt downstream-variant-500B
rs10150698 -- 102,511,539(+) GATGG(C/T)GGGGA nc-transcript-variant, upstream-variant-2KB
rs1046651 -- 102,504,679(-) TTCCT(A/G)GTACA utr-variant-3-prime
rs1061924 -- 102,509,318(+) GCCAT(C/T)GAAGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ANKRD9 Gene

Variant ID Type Subtype PubMed ID
nsv952254 CNV deletion 24416366
nsv832880 CNV loss 17160897
nsv565948 CNV gain 21841781
nsv522878 CNV loss 19592680
nsv470671 CNV gain 18288195
nsv1160203 CNV deletion 26073780
nsv1126377 CNV deletion 24896259
nsv1118293 CNV deletion 24896259
nsv1069821 CNV deletion 25765185
nsv1049544 CNV gain 25217958
esv3635555 CNV gain 21293372
dgv263n27 CNV gain 19166990

Variation tolerance for ANKRD9 Gene

Gene Damage Index Score: 0.45; 9.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD9 Gene

Disorders for ANKRD9 Gene

Relevant External Links for ANKRD9

Genetic Association Database (GAD)
ANKRD9
Human Genome Epidemiology (HuGE) Navigator
ANKRD9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD9

No disorders were found for ANKRD9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD9 Gene

Publications for ANKRD9 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. (PMID: 24952745) Arking D.E. … Newton-Cheh C. (Nat. Genet. 2014) 3 64
  5. New gene functions in megakaryopoiesis and platelet formation. (PMID: 22139419) Gieger C. … Soranzo N. (Nature 2011) 46 64

Products for ANKRD9 Gene

Sources for ANKRD9 Gene

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