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Aliases for ANKRD66 Gene

Aliases for ANKRD66 Gene

  • Ankyrin Repeat Domain 66 2 3 5

External Ids for ANKRD66 Gene

Previous GeneCards Identifiers for ANKRD66 Gene

  • GC06P046716

Summaries for ANKRD66 Gene

GeneCards Summary for ANKRD66 Gene

ANKRD66 (Ankyrin Repeat Domain 66) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD66 Gene

Genomics for ANKRD66 Gene

Regulatory Elements for ANKRD66 Gene

Enhancers for ANKRD66 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ANKRD66 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD66 Gene

46,746,917 bp from pter
46,759,506 bp from pter
12,590 bases
Plus strand

Genomic View for ANKRD66 Gene

Genes around ANKRD66 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD66 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD66 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD66 Gene

Proteins for ANKRD66 Gene

  • Protein details for ANKRD66 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 66
    Protein Accession:

    Protein attributes for ANKRD66 Gene

    251 amino acids
    Molecular mass:
    27916 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAG65187.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ANKRD66 Gene

Proteomics data for ANKRD66 Gene at MOPED

Post-translational modifications for ANKRD66 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD66 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD66 Gene

Domains & Families for ANKRD66 Gene

Gene Families for ANKRD66 Gene

Protein Domains for ANKRD66 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 ANK repeats.
  • Contains 3 ANK repeats.
genes like me logo Genes that share domains with ANKRD66: view

No data available for Suggested Antigen Peptide Sequences for ANKRD66 Gene

Function for ANKRD66 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD66 Gene

Localization for ANKRD66 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKRD66 Gene

Pathways & Interactions for ANKRD66 Gene

SuperPathways for ANKRD66 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD66 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD66 Gene

Drugs & Compounds for ANKRD66 Gene

No Compound Related Data Available

Transcripts for ANKRD66 Gene

mRNA/cDNA for ANKRD66 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD66 Gene

Ankyrin repeat domain 66:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD66 Gene

No ASD Table

Relevant External Links for ANKRD66 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD66 Gene

mRNA expression in normal human tissues for ANKRD66 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD66 Gene

This gene is overexpressed in Fallopian Tube (x8.1), Brain - Hypothalamus (x7.5), Cervix - Endocervix (x7.5), Brain - Caudate (basal ganglia) (x7.0), Brain - Hippocampus (x5.3), Brain - Amygdala (x4.9), and Lung (x4.8).

SOURCE GeneReport for Unigene cluster for ANKRD66 Gene Hs.736491

genes like me logo Genes that share expression patterns with ANKRD66: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ANKRD66 Gene

Orthologs for ANKRD66 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD66 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD66 35
  • 84.36 (n)
  • 82.47 (a)
ANKRD66 36
  • 81 (a)
(Canis familiaris)
Mammalia ANKRD66 35
  • 86.39 (n)
  • 84.18 (a)
ANKRD66 36
  • 85 (a)
(Mus musculus)
Mammalia Ankrd66 35
  • 80.56 (n)
  • 77.6 (a)
Ankrd66 16
Ankrd66 36
  • 78 (a)
(Pan troglodytes)
Mammalia LOC100614902 35
  • 99.07 (n)
  • 98.01 (a)
(Rattus norvegicus)
Mammalia Ankrd66 35
  • 82.3 (n)
  • 80.41 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD66 36
  • 79 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733445 35
  • 69.23 (n)
  • 66.92 (a)
(Danio rerio)
Actinopterygii LOC101886816 35
  • 59.92 (n)
  • 57.59 (a)
ANKRD66 36
  • 52 (a)
Species with no ortholog for ANKRD66:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD66 Gene

Gene Tree for ANKRD66 (if available)
Gene Tree for ANKRD66 (if available)

Paralogs for ANKRD66 Gene

(2) SIMAP similar genes for ANKRD66 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ANKRD66: view

No data available for Paralogs for ANKRD66 Gene

Variants for ANKRD66 Gene

Sequence variations from dbSNP and Humsavar for ANKRD66 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1362932 -- 46,748,342(+) CATGG(A/G)AAGTT intron-variant
rs1362933 -- 46,752,887(+) CAAAG(C/G)CTTTG intron-variant
rs1362934 -- 46,752,970(+) TGATT(C/T)TTGTG intron-variant
rs1362935 -- 46,753,052(+) GTACA(A/G)AGTGA intron-variant
rs1410821 -- 46,754,597(-) ACTCC(A/G)ATACT intron-variant

Variation tolerance for ANKRD66 Gene

Gene Damage Index Score: 5.82; 73.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD66 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANKRD66 Gene

Disorders for ANKRD66 Gene

Relevant External Links for ANKRD66

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD66 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD66 Gene

Publications for ANKRD66 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for ANKRD66 Gene

Sources for ANKRD66 Gene