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Aliases for ANKRD66 Gene

Aliases for ANKRD66 Gene

  • Ankyrin Repeat Domain 66 2 3

External Ids for ANKRD66 Gene

Summaries for ANKRD66 Gene

GeneCards Summary for ANKRD66 Gene

ANKRD66 (Ankyrin Repeat Domain 66) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD66 Gene

Genomics for ANKRD66 Gene

Genomic Location for ANKRD66 Gene

Start:
46,746,917 bp from pter
End:
46,759,506 bp from pter
Size:
12,590 bases
Orientation:
Plus strand

Genomic View for ANKRD66 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD66 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD66 Gene

No data available for Regulatory Elements for ANKRD66 Gene

Proteins for ANKRD66 Gene

  • Protein details for ANKRD66 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B4E2M5-ANR66_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 66
    Protein Accession:
    B4E2M5
    Secondary Accessions:

    Protein attributes for ANKRD66 Gene

    Size:
    251 amino acids
    Molecular mass:
    27916 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAG65187.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ANKRD66 Gene

Proteomics data for ANKRD66 Gene at MOPED

Post-translational modifications for ANKRD66 Gene

No Post-translational modifications

Other Protein References for ANKRD66 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD66 Gene

Domains for ANKRD66 Gene

Gene Families for ANKRD66 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD66 Gene

UniProtKB/Swiss-Prot:

ANR66_HUMAN
Similarity:
  • Contains 3 ANK repeats.:
    • B4E2M5
genes like me logo Genes that share domains with ANKRD66: view

Function for ANKRD66 Gene

Gene Ontology (GO) - Molecular Function for ANKRD66 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD66: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKRD66 Gene

Localization for ANKRD66 Gene

No data available for Gene Ontology (GO) - Cellular Components for ANKRD66 Gene

Pathways for ANKRD66 Gene

SuperPathways for ANKRD66 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD66 Gene

None

No data available for Pathways by source for ANKRD66 Gene

Transcripts for ANKRD66 Gene

mRNA/cDNA for ANKRD66 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD66 Gene

Ankyrin repeat domain 66:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD66 Gene

No ASD Table

Relevant External Links for ANKRD66 Gene

GeneLoc Exon Structure for
ANKRD66
ECgene alternative splicing isoforms for
ANKRD66

Expression for ANKRD66 Gene

mRNA expression in normal human tissues for ANKRD66 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD66 Gene

This gene is overexpressed in Fallopian Tube (8.1), Brain - Hypothalamus (7.5), Cervix - Endocervix (7.5), Brain - Caudate (basal ganglia) (7.0), Brain - Hippocampus (5.3), Brain - Amygdala (4.9), and Lung (4.8).

SOURCE GeneReport for Unigene cluster for ANKRD66 Gene Hs.736491

genes like me logo Genes that share expressions with ANKRD66: view

Orthologs for ANKRD66 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD66 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100614902 36
  • 99.07 (n)
  • 98.01 (a)
cow
(Bos Taurus)
Mammalia ANKRD66 36
  • 84.36 (n)
  • 82.47 (a)
ANKRD66 37
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD66 36
  • 86.39 (n)
  • 84.18 (a)
ANKRD66 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd66 36
  • 80.56 (n)
  • 77.6 (a)
Ankrd66 16
Ankrd66 37
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD66 37
  • 79 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd66 36
  • 82.3 (n)
  • 80.41 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733445 36
  • 69.23 (n)
  • 66.92 (a)
zebrafish
(Danio rerio)
Actinopterygii ANKRD66 37
  • 52 (a)
OneToOne
LOC101886816 36
  • 59.92 (n)
  • 57.59 (a)
Species with no ortholog for ANKRD66:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD66 Gene

ENSEMBL:
Gene Tree for ANKRD66 (if available)
TreeFam:
Gene Tree for ANKRD66 (if available)

Paralogs for ANKRD66 Gene

Selected SIMAP similar genes for ANKRD66 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ANKRD66: view

No data available for Paralogs for ANKRD66 Gene

Variants for ANKRD66 Gene

Sequence variations from dbSNP and Humsavar for ANKRD66 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1345528 -- 46,757,500(+) AGCAA(C/T)TTATT intron-variant
rs1360073 -- 46,754,826(-) CATCT(C/T)AATTG intron-variant
rs1362932 -- 46,748,342(+) CATGG(A/G)AAGTT intron-variant
rs1362933 -- 46,752,887(+) CAAAG(C/G)CTTTG intron-variant
rs1362934 -- 46,752,970(+) TGATT(C/T)TTGTG intron-variant

Relevant External Links for ANKRD66 Gene

HapMap Linkage Disequilibrium report
ANKRD66

No data available for Structural Variations from Database of Genomic Variants (DGV) for ANKRD66 Gene

Disorders for ANKRD66 Gene

No disorders were found for ANKRD66 Gene.

No data available for UniProtKB/Swiss-Prot for ANKRD66 Gene

Publications for ANKRD66 Gene

  1. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ANKRD66 Gene

Sources for ANKRD66 Gene

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