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Aliases for ANKRD65 Gene

Aliases for ANKRD65 Gene

  • Ankyrin Repeat Domain 65 2 3

External Ids for ANKRD65 Gene

Previous GeneCards Identifiers for ANKRD65 Gene

  • GC01M001355
  • GC01M001358

Summaries for ANKRD65 Gene

GeneCards Summary for ANKRD65 Gene

ANKRD65 (Ankyrin Repeat Domain 65) is a Protein Coding gene. An important paralog of this gene is ANKRD52.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD65 Gene

Genomics for ANKRD65 Gene

Genomic Location for ANKRD65 Gene

Start:
1,418,420 bp from pter
End:
1,421,769 bp from pter
Size:
3,350 bases
Orientation:
Minus strand

Genomic View for ANKRD65 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD65 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD65 Gene

No data available for Regulatory Elements for ANKRD65 Gene

Proteins for ANKRD65 Gene

  • Protein details for ANKRD65 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    E5RJM6-ANR65_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 65
    Protein Accession:
    E5RJM6
    Secondary Accessions:
    • J3KR93

    Protein attributes for ANKRD65 Gene

    Size:
    399 amino acids
    Molecular mass:
    41497 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD65 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKRD65 Gene

Proteomics data for ANKRD65 Gene at MOPED

Post-translational modifications for ANKRD65 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD65 Gene

No data available for DME Specific Peptides for ANKRD65 Gene

Domains for ANKRD65 Gene

Gene Families for ANKRD65 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD65 Gene

Graphical View of Domain Structure for InterPro Entry

E5RJM6

UniProtKB/Swiss-Prot:

ANR65_HUMAN :
  • E5RJM6
Similarity:
  • Contains 10 ANK repeats.
genes like me logo Genes that share domains with ANKRD65: view

No data available for Suggested Antigen Peptide Sequences for ANKRD65 Gene

Function for ANKRD65 Gene

Gene Ontology (GO) - Molecular Function for ANKRD65 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD65: view

Phenotypes for ANKRD65 Gene

GenomeRNAi human phenotypes for ANKRD65:
genes like me logo Genes that share phenotypes with ANKRD65: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKRD65 Gene

Localization for ANKRD65 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKRD65 Gene

Pathways for ANKRD65 Gene

SuperPathways for ANKRD65 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD65 Gene

None

No data available for Pathways by source for ANKRD65 Gene

Transcripts for ANKRD65 Gene

Unigene Clusters for ANKRD65 Gene

Ankyrin repeat domain 65:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD65

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ANKRD65
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD65 Gene

No ASD Table

Relevant External Links for ANKRD65 Gene

GeneLoc Exon Structure for
ANKRD65
ECgene alternative splicing isoforms for
ANKRD65

Expression for ANKRD65 Gene

mRNA expression in normal human tissues for ANKRD65 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ANKRD65 Gene

SOURCE GeneReport for Unigene cluster for ANKRD65 Gene Hs.381222

genes like me logo Genes that share expressions with ANKRD65: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD65 Gene

Orthologs for ANKRD65 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD65 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC457197 35
  • 97.49 (n)
  • 96.58 (a)
cow
(Bos Taurus)
Mammalia ANKRD65 35
  • 79.22 (n)
  • 76.15 (a)
ANKRD65 36
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD65 35
  • 79.67 (n)
  • 79.95 (a)
ANKRD65 36
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd65 35
  • 69.96 (n)
  • 67.51 (a)
Ankrd65 16
rat
(Rattus norvegicus)
Mammalia Ankrd65 35
  • 71.47 (n)
  • 68.08 (a)
lizard
(Anolis carolinensis)
Reptilia ANKRD65 36
  • 41 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd65 35
  • 49 (n)
  • 43.46 (a)
zebrafish
(Danio rerio)
Actinopterygii ANKRD65 36
  • 34 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea trp-4 36
  • 8 (a)
OneToOne
Species with no ortholog for ANKRD65:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ANKRD65 Gene

ENSEMBL:
Gene Tree for ANKRD65 (if available)
TreeFam:
Gene Tree for ANKRD65 (if available)

Paralogs for ANKRD65 Gene

Paralogs for ANKRD65 Gene

genes like me logo Genes that share paralogs with ANKRD65: view

Variants for ANKRD65 Gene

Sequence variations from dbSNP and Humsavar for ANKRD65 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs904589 -- 1,419,135(-) GGGGG(C/G)AGAAG missense, reference, utr-variant-3-prime
rs1695853 -- 1,423,368(-) GTCAT(C/T)GGAAA upstream-variant-2KB
rs1695854 -- 1,423,343(-) CAGAC(A/C)CCGAG upstream-variant-2KB
rs1695855 -- 1,423,062(-) GCATT(A/G)CCATG upstream-variant-2KB
rs1695856 -- 1,422,946(-) gggcc(A/G)gcttc upstream-variant-2KB

Relevant External Links for ANKRD65 Gene

HapMap Linkage Disequilibrium report
ANKRD65

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANKRD65 Gene

Disorders for ANKRD65 Gene

No disorders were found for ANKRD65 Gene.

No data available for UniProtKB/Swiss-Prot for ANKRD65 Gene

Publications for ANKRD65 Gene

  1. Transcription of human endogenous retroviral long terminal repeat (LTR) sequence in a lung cancer cell line. (PMID: 2302192) Tomita N. … Matsubara K. (Biochem. Biophys. Res. Commun. 1990) 3
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PMID: 24163370) Lu L. … Zhang L. (J. Biol. Chem. 2013) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for ANKRD65 Gene

Sources for ANKRD65 Gene

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