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Aliases for ANKRD65 Gene

Aliases for ANKRD65 Gene

  • Ankyrin Repeat Domain 65 2 3 5

External Ids for ANKRD65 Gene

Previous GeneCards Identifiers for ANKRD65 Gene

  • GC01M001355
  • GC01M001358

Summaries for ANKRD65 Gene

GeneCards Summary for ANKRD65 Gene

ANKRD65 (Ankyrin Repeat Domain 65) is a Protein Coding gene. An important paralog of this gene is TANC1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD65 Gene

Genomics for ANKRD65 Gene

Regulatory Elements for ANKRD65 Gene

Enhancers for ANKRD65 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ANKRD65 on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD65 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD65 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD65 Gene

1,418,420 bp from pter
1,421,820 bp from pter
3,401 bases
Minus strand

Genomic View for ANKRD65 Gene

Genes around ANKRD65 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD65 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD65 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD65 Gene

Proteins for ANKRD65 Gene

  • Protein details for ANKRD65 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 65
    Protein Accession:
    Secondary Accessions:
    • J3KR93

    Protein attributes for ANKRD65 Gene

    399 amino acids
    Molecular mass:
    41497 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD65 Gene


neXtProt entry for ANKRD65 Gene

Proteomics data for ANKRD65 Gene at MOPED

Post-translational modifications for ANKRD65 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD65 Gene

No data available for DME Specific Peptides for ANKRD65 Gene

Domains & Families for ANKRD65 Gene

Gene Families for ANKRD65 Gene

Protein Domains for ANKRD65 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 10 ANK repeats.
  • Contains 10 ANK repeats.
genes like me logo Genes that share domains with ANKRD65: view

No data available for Suggested Antigen Peptide Sequences for ANKRD65 Gene

Function for ANKRD65 Gene

Phenotypes for ANKRD65 Gene

genes like me logo Genes that share phenotypes with ANKRD65: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD65 Gene

Localization for ANKRD65 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKRD65 Gene

Pathways & Interactions for ANKRD65 Gene

SuperPathways for ANKRD65 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD65 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD65 Gene

Drugs & Compounds for ANKRD65 Gene

No Compound Related Data Available

Transcripts for ANKRD65 Gene

Unigene Clusters for ANKRD65 Gene

Ankyrin repeat domain 65:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD65 Gene

No ASD Table

Relevant External Links for ANKRD65 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD65 Gene

mRNA expression in normal human tissues for ANKRD65 Gene

Protein differential expression in normal tissues from HIPED for ANKRD65 Gene

This gene is overexpressed in Pancreatic juice (64.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD65 Gene

SOURCE GeneReport for Unigene cluster for ANKRD65 Gene Hs.381222

genes like me logo Genes that share expression patterns with ANKRD65: view

Protein tissue co-expression partners for ANKRD65 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD65 Gene

Orthologs for ANKRD65 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD65 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD65 35
  • 79.22 (n)
  • 76.15 (a)
ANKRD65 36
  • 73 (a)
(Canis familiaris)
Mammalia ANKRD65 35
  • 79.67 (n)
  • 79.95 (a)
ANKRD65 36
  • 67 (a)
(Mus musculus)
Mammalia Ankrd65 35
  • 69.96 (n)
  • 67.51 (a)
Ankrd65 16
(Pan troglodytes)
Mammalia LOC457197 35
  • 97.49 (n)
  • 96.58 (a)
(Rattus norvegicus)
Mammalia Ankrd65 35
  • 71.47 (n)
  • 68.08 (a)
(Anolis carolinensis)
Reptilia ANKRD65 36
  • 41 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd65 35
  • 49 (n)
  • 43.46 (a)
(Danio rerio)
Actinopterygii ANKRD65 36
  • 34 (a)
(Caenorhabditis elegans)
Secernentea trp-4 36
  • 8 (a)
Species with no ortholog for ANKRD65:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ANKRD65 Gene

Gene Tree for ANKRD65 (if available)
Gene Tree for ANKRD65 (if available)

Paralogs for ANKRD65 Gene

genes like me logo Genes that share paralogs with ANKRD65: view

Variants for ANKRD65 Gene

Sequence variations from dbSNP and Humsavar for ANKRD65 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs4970447 -- 1,418,181(+) CCACC(A/G)TGGGG downstream-variant-500B
rs4970448 -- 1,418,223(+) CACCG(A/G)GGCAA downstream-variant-500B
rs11488462 -- 1,418,000(+) TCACA(C/T)GATCT downstream-variant-500B
rs61767983 -- 1,418,129(+) TGTCC(A/G)GACTC downstream-variant-500B
rs78991109 -- 1,418,221(+) TCCAC(C/T)GAGGC downstream-variant-500B

Variation tolerance for ANKRD65 Gene

Gene Damage Index Score: 9.12; 87.74% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ANKRD65 Gene

Disorders for ANKRD65 Gene

Relevant External Links for ANKRD65

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD65 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD65 Gene

Publications for ANKRD65 Gene

  1. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PMID: 24163370) Lu L. … Zhang L. (J. Biol. Chem. 2013) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  4. Transcription of human endogenous retroviral long terminal repeat (LTR) sequence in a lung cancer cell line. (PMID: 2302192) Tomita N. … Matsubara K. (Biochem. Biophys. Res. Commun. 1990) 3

Products for ANKRD65 Gene

Sources for ANKRD65 Gene