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Aliases for ANKRD63 Gene

Aliases for ANKRD63 Gene

  • Ankyrin Repeat Domain 63 2 3

External Ids for ANKRD63 Gene

Previous GeneCards Identifiers for ANKRD63 Gene

  • GC15M040574

Summaries for ANKRD63 Gene

GeneCards Summary for ANKRD63 Gene

ANKRD63 (Ankyrin Repeat Domain 63) is a Protein Coding gene. An important paralog of this gene is ANKRD46.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD63 Gene

Genomics for ANKRD63 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ANKRD63 Gene

Start:
40,281,444 bp from pter
End:
40,282,586 bp from pter
Size:
1,143 bases
Orientation:
Minus strand

Genomic View for ANKRD63 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD63 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD63 Gene

No data available for Regulatory Elements for ANKRD63 Gene

Proteins for ANKRD63 Gene

  • Protein details for ANKRD63 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9JTQ0-ANR63_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 63
    Protein Accession:
    C9JTQ0
    Secondary Accessions:

    Protein attributes for ANKRD63 Gene

    Size:
    380 amino acids
    Molecular mass:
    39620 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD63 Gene

Proteomics data for ANKRD63 Gene at MOPED

Post-translational modifications for ANKRD63 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD63 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD63 Gene

Domains for ANKRD63 Gene

Gene Families for ANKRD63 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD63 Gene

Suggested Antigen Peptide Sequences for ANKRD63 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

C9JTQ0

UniProtKB/Swiss-Prot:

ANR63_HUMAN :
  • C9JTQ0
Similarity:
  • Contains 5 ANK repeats.
genes like me logo Genes that share domains with ANKRD63: view

Function for ANKRD63 Gene

Gene Ontology (GO) - Molecular Function for ANKRD63 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD63: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKRD63 Gene

Localization for ANKRD63 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKRD63 Gene

Pathways for ANKRD63 Gene

SuperPathways for ANKRD63 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD63 Gene

None

No data available for Pathways by source for ANKRD63 Gene

Transcripts for ANKRD63 Gene

mRNA/cDNA for ANKRD63 Gene

(0) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD63 Gene

Ankyrin repeat domain 63:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD63

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD63 Gene

No ASD Table

Relevant External Links for ANKRD63 Gene

GeneLoc Exon Structure for
ANKRD63
ECgene alternative splicing isoforms for
ANKRD63

Expression for ANKRD63 Gene

mRNA expression in normal human tissues for ANKRD63 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD63 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (18.8), Brain - Putamen (basal ganglia) (9.7), and Brain - Caudate (basal ganglia) (8.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ANKRD63 Gene

SOURCE GeneReport for Unigene cluster for ANKRD63 Gene Hs.711376

genes like me logo Genes that share expressions with ANKRD63: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ANKRD63 Gene

Orthologs for ANKRD63 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ANKRD63 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD63 35
  • 99.47 (n)
  • 99.47 (a)
ANKRD63 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ANKRD63 35
  • 87.11 (n)
  • 92.89 (a)
ANKRD63 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD63 35
  • 90 (n)
  • 95 (a)
ANKRD63 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd63 35
  • 86.58 (n)
  • 92.11 (a)
Ankrd63 16
Ankrd63 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd63 35
  • 86.93 (n)
  • 91.84 (a)
Species with no ortholog for ANKRD63:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKRD63 Gene

ENSEMBL:
Gene Tree for ANKRD63 (if available)
TreeFam:
Gene Tree for ANKRD63 (if available)

Paralogs for ANKRD63 Gene

Paralogs for ANKRD63 Gene

Selected SIMAP similar genes for ANKRD63 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKRD63: view

Variants for ANKRD63 Gene

Sequence variations from dbSNP and Humsavar for ANKRD63 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs4924445 -- 40,281,212(+) AACCA(A/G)TCAAT downstream-variant-500B
rs4924446 -- 40,281,515(+) GACAG(A/G)CAGAG missense, reference
rs7180770 -- 40,281,204(+) GCCTA(C/T)GGAAC downstream-variant-500B
rs7181872 -- 40,281,653(+) ACTGA(C/G)GCCAA reference, missense
rs12440450 -- 40,281,474(+) GCCTC(G/T)GTGCC synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for ANKRD63 Gene

Variant ID Type Subtype PubMed ID
nsv904095 CNV Loss 21882294
nsv471240 CNV Loss 18288195
esv34145 CNV Loss 18971310
dgv2359n71 CNV Loss 21882294
nsv510660 CNV Loss 20534489
nsv517541 CNV Loss 19592680
nsv904098 CNV Loss 21882294
nsv457118 CNV Loss 19166990

Relevant External Links for ANKRD63 Gene

HapMap Linkage Disequilibrium report
ANKRD63

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD63 Gene

Disorders for ANKRD63 Gene

No disorders were found for ANKRD63 Gene.

No data available for UniProtKB/Swiss-Prot for ANKRD63 Gene

Publications for ANKRD63 Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for ANKRD63 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ANKRD63
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD63
    • Block miRNA regulation of ANKRD63 using miScript Target Protectors

    Sources for ANKRD63 Gene

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