ANKRD62 Gene
protein-coding GIFtS: 31
GCID: GC18P012094 (predicted)
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ankyrin repeat domain 62
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Aliases
for ANKRD62 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankyrin Repeat Domain 621 2 | | DKFZp779B16341 2 | | Ankyrin Repeat Domain-Containing Protein 622 |
Export aliases for ANKRD62 gene to outside databasesPrevious GC identifers: GC18P012091 GC18P012093 |
Summaries
for ANKRD62 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ANKRD62 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NT_010859.14 NC_018929.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANKRD62 gene promoter:
C/EBPbeta Nkx2-2 Nkx2-5 E47 FOXL1 HEN1 CBF-B CBF-A NF-Y CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKRD62
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD62 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18p11.21 Ensembl cytogenetic band: 18p11.21 HGNC cytogenetic band: 18p11.21ANKRD62 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18P012094: view genomic region
(about GC identifiers)
Start:
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12,093,848 bp from pter |
End:
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12,129,763 bp from pter |
Size:
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35,916 bases |
Orientation:
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plus strand |
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Proteins
for ANKRD62 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANR62_HUMAN, A6NC57 (See
protein sequence)Recommended Name: Ankyrin repeat domain-containing protein 62 Size: 917 amino acids; 106446 Da
Sequence caution: Sequence=BX649021; Type=Erroneous termination; Positions=558; Note=Translated as Trp;Alternative splicing: 3 isoforms: A6NC57-1 A6NC57-2 A6NC57-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ANKRD62: NX_A6NC57
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A6NC57
ANKRD62 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000466783 ENSP00000467740 ENSP00000405628 ENSP00000326572
Human Recombinant Protein Products:
ANKRD62 Antibody Products:
Assay Products for ANKRD62: |
Protein
Domains /
Families
for ANKRD62 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKRD62 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A6NC57ProtoNet protein and cluster: A6NC57 UniProtKB/Swiss-Prot: ANR62_HUMAN, A6NC57Similarity: Contains 5 ANK repeats |
Function
for ANKRD62 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD62 |
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Pathways & Interactions
for ANKRD62 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD62
|
Drugs & Compounds
for ANKRD62 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANKRD62
Search CenterWatch for drugs/clinical trials and news about ANKRD62 / ANR62 
|
Transcripts
for ANKRD62 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for ANKRD62: Ankyrin repeat domain 62 Hs.448906 [show with all ESTs]Unigene Representative Sequence: BX6490214 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000586406 ENST00000587848 ENST00000418274(uc002kqs.3) ENST00000314074(uc002kqr.3)
Additional cDNA sequence: BX648696.1 BX649021.1 2 DOTS entries: DT.40270388 DT.101960442 2 AceView cDNA sequences: BX648696 BX649021
GeneLoc Exon Structure
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Expression
for ANKRD62 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKRD62 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGATCCATA
About this image
See ANKRD62 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.448906
SABiosciences Custom PCR Arrays for ANKRD62
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ANKRD62 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD62 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD62 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD62 |
Orthologs
for ANKRD62 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for ANKRD62 gene from 3/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ANKRD626 |
Uncharacterized protein |
19(a) |
1 → many |
1(26091172-26138404) |
lizard
(Anolis carolinensis) |
Reptilia |
ANKRD626 |
-- |
11(a) |
1 → many |
GL344195.1(39104-48393) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch211-272n13.36 |
si:ch211-272n13.3 |
6(a) |
1 → many |
25(3581527-3655709) |
ENSEMBL Gene Tree for ANKRD62 (if available)
TreeFam Gene Tree for ANKRD62 (if available) |
Paralogs
for ANKRD62 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANKRD62 gene
- POTEF2 POTEI2 ANKRD30A2 ANKRD362 ANKRD72 POTEB2 ANKRD30BL2 ANKRD20A32
- POTEH2 ENSG000001552822 ANKRD30B2 ENSG000002663022 ANKRD36C2 POTEJ2 POTEC2 ANKRD20A22
- POTEG2 ANKRD262 ANKRD18A2 ENSG000001882192 POTEM2 ANKRD20A12 LOC1009963312 CCDC144A2
- POTED2 ANKRD20A42 ANKRD18B2 LOC1002889662
18/29 SIMAP similar genes for ANKRD62 using alignment to 4 protein entries: ANR62_HUMAN (see all proteins)
(see all similar genes):ANKRD36BP1 ANKRD19P ANKRD20A5P ANKRD26P1 ANKRD30BL ANKRD7
DKFZp781D1722 ANKRD36 LOC254750 POTEA POTEF POTEM
ANKRD36C POTEG POTEH POTEC PRED4 ANKRD36B
ANKRD62 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ANKRD62
PGOHUM00000246201
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Genomic Variants
for ANKRD62 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for ANKRD62 (12093848 - 12129763 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ANKRD62: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD62 |
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Disorders
/ Diseases
for ANKRD62 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ANKRD62 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKRD62 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ANKRD62) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)2 Nusbaum C.... Lander E.S. (2005)
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External Searches for ANKRD62 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ANKRD62 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKRD62 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANKRD62 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANKRD62 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ANKRD62 gene:
Search GeneIP for patents involving ANKRD62
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANKRD62 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKRD62 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD62 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD62 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKRD62 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD62 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD62 |
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 |  |  |  | |
| | | | Search Tocris compounds for ANKRD62 |
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 | | | ANKRD62 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD62 |
|  |  |  | | | | Search ThermoFisher Antibodies for ANKRD62 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANKRD62 |
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