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Aliases for ANKRD61 Gene

Aliases for ANKRD61 Gene

  • Ankyrin Repeat Domain 61 2 3 5

External Ids for ANKRD61 Gene

Previous GeneCards Identifiers for ANKRD61 Gene

  • GC00U923118
  • GC07P006071

Summaries for ANKRD61 Gene

GeneCards Summary for ANKRD61 Gene

ANKRD61 (Ankyrin Repeat Domain 61) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD61 Gene

Genomics for ANKRD61 Gene

Regulatory Elements for ANKRD61 Gene

Enhancers for ANKRD61 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G005551 2.1 FANTOM5 Ensembl ENCODE dbSUPER 23.8 -475.6 -475600 7.6 CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 USP42 ANKRD61 AP5Z1 ZNF890P EIF2AK1 CCZ1 ACTB WIPI2 ENSG00000272719 GC07M005529
GH07G005486 1.6 Ensembl ENCODE dbSUPER 22.2 -543.8 -543779 2.4 HDGF PKNOX1 AGO1 ARID4B SIN3A DMAP1 ZNF2 ZNF143 KLF13 DEK ANKRD61 USP42 AP5Z1 CCZ1 ENSG00000230733 FBXL18 GC07M005483 MIR589
GH07G005379 1.1 dbSUPER 23.8 -650.9 -650937 2.6 HDGF PKNOX1 AGO1 ZFP64 ARID4B SIN3A DMAP1 FEZF1 ZNF2 ZBTB7B USP42 ANKRD61 AP5Z1 ENSG00000188365 ENSG00000241269 TNRC18 LOC100129484 RNF216P1 GC07P005375
GH07G005456 1.6 Ensembl ENCODE dbSUPER 13 -573.5 -573503 1.9 PKNOX1 CREB3L1 ARNT ZNF766 REST ZNF592 MEF2D SMARCA4 NBN KDM1A AP5Z1 ANKRD61 USP42 GC07P005444 ENSG00000230733
GH07G005523 1.8 FANTOM5 ENCODE dbSUPER 11.3 -501.9 -501879 11.1 CREB3L1 MLX AGO1 FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC CCZ1 AP5Z1 ANKRD61 USP42 FBXL18 WIPI2 ACTB RBAK PIR61399 GC07M005530
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ANKRD61 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD61 Gene

Chromosome:
7
Start:
6,031,376 bp from pter
End:
6,036,552 bp from pter
Size:
5,177 bases
Orientation:
Plus strand

Genomic View for ANKRD61 Gene

Genes around ANKRD61 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD61 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD61 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD61 Gene

Proteins for ANKRD61 Gene

  • Protein details for ANKRD61 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGH8-ANR61_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 61
    Protein Accession:
    A6NGH8

    Protein attributes for ANKRD61 Gene

    Size:
    418 amino acids
    Molecular mass:
    46141 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD61 Gene

Post-translational modifications for ANKRD61 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD61 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD61 Gene

Domains & Families for ANKRD61 Gene

Gene Families for ANKRD61 Gene

Protein Domains for ANKRD61 Gene

Suggested Antigen Peptide Sequences for ANKRD61 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ANKRD61: view

No data available for UniProtKB/Swiss-Prot for ANKRD61 Gene

Function for ANKRD61 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD61 Gene

Localization for ANKRD61 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ANKRD61 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD61 Gene

Pathways & Interactions for ANKRD61 Gene

SuperPathways for ANKRD61 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD61 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD61 Gene

Drugs & Compounds for ANKRD61 Gene

No Compound Related Data Available

Transcripts for ANKRD61 Gene

mRNA/cDNA for ANKRD61 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD61 Gene

Ankyrin repeat domain 61:
Representative Sequences:

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD61 Gene

No ASD Table

Relevant External Links for ANKRD61 Gene

GeneLoc Exon Structure for
ANKRD61
ECgene alternative splicing isoforms for
ANKRD61

Expression for ANKRD61 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ANKRD61 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD61 Gene

This gene is overexpressed in Testis (x9.9).

Protein differential expression in normal tissues from HIPED for ANKRD61 Gene

This gene is overexpressed in Heart (60.8) and Blymphocyte (8.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD61 Gene



Protein tissue co-expression partners for ANKRD61 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ANKRD61 Gene:

ANKRD61

SOURCE GeneReport for Unigene cluster for ANKRD61 Gene:

Hs.744468
genes like me logo Genes that share expression patterns with ANKRD61: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ANKRD61 Gene

Orthologs for ANKRD61 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD61 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD61 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD61 35 34
  • 81.65 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd61 34 16 35
  • 77.59 (n)
rat
(Rattus norvegicus)
Mammalia Ankrd61 34
  • 77.19 (n)
cow
(Bos Taurus)
Mammalia ANKRD61 35 34
  • 73.48 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKRD61 35
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD61 35
  • 62 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC101752127 34
  • 58.87 (n)
Species where no ortholog for ANKRD61 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKRD61 Gene

ENSEMBL:
Gene Tree for ANKRD61 (if available)
TreeFam:
Gene Tree for ANKRD61 (if available)

Paralogs for ANKRD61 Gene

(2) SIMAP similar genes for ANKRD61 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ANKRD61: view

No data available for Paralogs for ANKRD61 Gene

Variants for ANKRD61 Gene

Sequence variations from dbSNP and Humsavar for ANKRD61 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000480877 -- 6,030,727(+) CTCTT(C/G)ACCTC intron-variant, upstream-variant-2KB
rs1000966395 -- 6,033,220(+) TGCCT(C/T)GGCCT intron-variant
rs1001190267 -- 6,033,331(+) CATAC(A/C)TTTTT intron-variant
rs1001223422 -- 6,030,472(+) TGGAC(A/G)GGTGA intron-variant, upstream-variant-2KB
rs1001275845 -- 6,030,671(+) TTTTT(A/C/G/T)TATTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ANKRD61 Gene

Variant ID Type Subtype PubMed ID
esv1385792 CNV deletion 17803354
esv1914954 OTHER inversion 16254605
esv3891031 CNV loss 25118596
esv988101 CNV deletion 20482838
nsv1018388 CNV gain 25217958
nsv1034916 CNV gain 25217958
nsv1114913 CNV deletion 24896259
nsv436904 CNV insertion 17901297
nsv471823 CNV novel sequence insertion 20440878
nsv605998 CNV loss 21841781
nsv7392 OTHER inversion 18451855
nsv830894 CNV loss 17160897

Variation tolerance for ANKRD61 Gene

Gene Damage Index Score: 11.01; 92.07% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD61 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD61

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD61 Gene

Disorders for ANKRD61 Gene

Relevant External Links for ANKRD61

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD61

No disorders were found for ANKRD61 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD61 Gene

Publications for ANKRD61 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4 64

Products for ANKRD61 Gene

Sources for ANKRD61 Gene

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