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Aliases for ANKRD60 Gene

Aliases for ANKRD60 Gene

  • Ankyrin Repeat Domain 60 2 3 5
  • C20orf86 3 4
  • Chromosome 20 Open Reading Frame 86 2
  • BA196N14.3 3

External Ids for ANKRD60 Gene

Previous HGNC Symbols for ANKRD60 Gene

  • C20orf86

Previous GeneCards Identifiers for ANKRD60 Gene

  • GC20M056227
  • GC20M056793
  • GC20M053576

Summaries for ANKRD60 Gene

GeneCards Summary for ANKRD60 Gene

ANKRD60 (Ankyrin Repeat Domain 60) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD60 Gene

Genomics for ANKRD60 Gene

Regulatory Elements for ANKRD60 Gene

Promoters for ANKRD60 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD60 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD60 Gene

Chromosome:
20
Start:
58,216,126 bp from pter
End:
58,228,653 bp from pter
Size:
12,528 bases
Orientation:
Minus strand

Genomic View for ANKRD60 Gene

Genes around ANKRD60 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD60 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD60 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD60 Gene

Proteins for ANKRD60 Gene

  • Protein details for ANKRD60 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BZ19-ANR60_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 60
    Protein Accession:
    Q9BZ19
    Secondary Accessions:
    • Q4VXE6

    Protein attributes for ANKRD60 Gene

    Size:
    345 amino acids
    Molecular mass:
    37630 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI94996.3; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ANKRD60 Gene

Proteomics data for ANKRD60 Gene at MOPED

Post-translational modifications for ANKRD60 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD60 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD60 Gene

Domains & Families for ANKRD60 Gene

Gene Families for ANKRD60 Gene

Protein Domains for ANKRD60 Gene

Suggested Antigen Peptide Sequences for ANKRD60 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BZ19

UniProtKB/Swiss-Prot:

ANR60_HUMAN :
  • Contains 1 ubiquitin-like domain.
  • Contains 2 ANK repeats.
Domain:
  • Contains 1 ubiquitin-like domain.
Similarity:
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with ANKRD60: view

Function for ANKRD60 Gene

Phenotypes for ANKRD60 Gene

GenomeRNAi human phenotypes for ANKRD60:
genes like me logo Genes that share phenotypes with ANKRD60: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD60 Gene

Localization for ANKRD60 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD60 Gene COMPARTMENTS Subcellular localization image for ANKRD60 gene
Compartment Confidence
cytosol 3
mitochondrion 3
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD60 Gene

Pathways & Interactions for ANKRD60 Gene

SuperPathways for ANKRD60 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD60 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD60 Gene

Drugs & Compounds for ANKRD60 Gene

No Compound Related Data Available

Transcripts for ANKRD60 Gene

mRNA/cDNA for ANKRD60 Gene

(3) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD60 Gene

No ASD Table

Relevant External Links for ANKRD60 Gene

GeneLoc Exon Structure for
ANKRD60
ECgene alternative splicing isoforms for
ANKRD60

Expression for ANKRD60 Gene

mRNA expression in normal human tissues for ANKRD60 Gene

mRNA differential expression in normal tissues according to GTEx for ANKRD60 Gene

This gene is overexpressed in Testis (x52.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD60 Gene



genes like me logo Genes that share expression patterns with ANKRD60: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ANKRD60 Gene

Orthologs for ANKRD60 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD60 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD60 36
  • 98 (a)
OneToOne
ANKRD60 35
  • 99.5 (n)
  • 98.49 (a)
cow
(Bos Taurus)
Mammalia ANKRD60 36
  • 60 (a)
OneToOne
ANKRD60 35
  • 79.19 (n)
  • 72.49 (a)
dog
(Canis familiaris)
Mammalia ANKRD60 35
  • 78.07 (n)
  • 69.43 (a)
ANKRD60 36
  • 60 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd60 16
Ankrd60 36
  • 63 (a)
OneToOne
Ankrd60 35
  • 73.16 (n)
  • 66.67 (a)
oppossum
(Monodelphis domestica)
Mammalia ANKRD60 36
  • 57 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd60 35
  • 72.65 (n)
  • 68.21 (a)
chicken
(Gallus gallus)
Aves ANKRD60 35
  • 56.65 (n)
  • 47.85 (a)
ANKRD60 36
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD60 36
  • 40 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd60 35
  • 51.44 (n)
  • 44.44 (a)
Species with no ortholog for ANKRD60:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKRD60 Gene

ENSEMBL:
Gene Tree for ANKRD60 (if available)
TreeFam:
Gene Tree for ANKRD60 (if available)

Paralogs for ANKRD60 Gene

(2) SIMAP similar genes for ANKRD60 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ANKRD60: view

No data available for Paralogs for ANKRD60 Gene

Variants for ANKRD60 Gene

Sequence variations from dbSNP and Humsavar for ANKRD60 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs584855 - 58,218,650(+) CAGGC(A/G)GTGTG reference, missense
rs486302 -- 58,225,569(+) CAGAG(A/G)GGGAA intron-variant, upstream-variant-2KB
rs521615 -- 58,221,211(+) CCTGA(C/T)TGGTG intron-variant
rs550222 -- 58,229,833(+) TATCT(G/T)TGCAT upstream-variant-2KB
rs550913 -- 58,220,333(+) ACTCC(A/G)CATTG intron-variant

Variation tolerance for ANKRD60 Gene

Gene Damage Index Score: 7.62; 82.70% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD60 Gene

HapMap Linkage Disequilibrium report
ANKRD60

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ANKRD60 Gene

Disorders for ANKRD60 Gene

Relevant External Links for ANKRD60

Genetic Association Database (GAD)
ANKRD60
Human Genome Epidemiology (HuGE) Navigator
ANKRD60
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD60

No disorders were found for ANKRD60 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD60 Gene

Publications for ANKRD60 Gene

  1. Identification of 15 loci influencing height in a Korean population. (PMID: 19893584) Kim J.J. … Lee J.K. (J. Hum. Genet. 2010) 3 48 67
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3
  3. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PMID: 19913121) Talmud P.J. … . (Am. J. Hum. Genet. 2009) 3
  4. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3

Products for ANKRD60 Gene

Sources for ANKRD60 Gene

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