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Aliases for ANKRD55 Gene

Aliases for ANKRD55 Gene

  • Ankyrin Repeat Domain 55 2 3

External Ids for ANKRD55 Gene

Previous GeneCards Identifiers for ANKRD55 Gene

  • GC05M055432
  • GC05M052368
  • GC05M055395

Summaries for ANKRD55 Gene

GeneCards Summary for ANKRD55 Gene

ANKRD55 (Ankyrin Repeat Domain 55) is a Protein Coding gene. Diseases associated with ANKRD55 include polyarticular onset juvenile idiopathic arthritis and oligoarticular juvenile arthritis.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD55 Gene

Genomics for ANKRD55 Gene

Regulatory Elements for ANKRD55 Gene

Genomic Location for ANKRD55 Gene

56,099,678 bp from pter
56,233,359 bp from pter
133,682 bases
Minus strand

Genomic View for ANKRD55 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD55 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD55 Gene

Proteins for ANKRD55 Gene

  • Protein details for ANKRD55 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 55
    Protein Accession:
    Secondary Accessions:
    • B3KVT8
    • Q3KP45
    • Q9HAD3

    Protein attributes for ANKRD55 Gene

    614 amino acids
    Molecular mass:
    68414 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD55 Gene


neXtProt entry for ANKRD55 Gene

Proteomics data for ANKRD55 Gene at MOPED

Post-translational modifications for ANKRD55 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD55 Gene

No data available for DME Specific Peptides for ANKRD55 Gene

Domains & Families for ANKRD55 Gene

Gene Families for ANKRD55 Gene

Protein Domains for ANKRD55 Gene

Suggested Antigen Peptide Sequences for ANKRD55 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 9 ANK repeats.
  • Contains 9 ANK repeats.
genes like me logo Genes that share domains with ANKRD55: view

Function for ANKRD55 Gene

Gene Ontology (GO) - Molecular Function for ANKRD55 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD55: view

Phenotypes for ANKRD55 Gene

GenomeRNAi human phenotypes for ANKRD55:
genes like me logo Genes that share phenotypes with ANKRD55: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD55

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ANKRD55 Gene

Localization for ANKRD55 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ANKRD55 Gene

Pathways & Interactions for ANKRD55 Gene

SuperPathways for ANKRD55 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD55 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD55 Gene

Drugs & Compounds for ANKRD55 Gene

No Compound Related Data Available

Transcripts for ANKRD55 Gene

Unigene Clusters for ANKRD55 Gene

Ankyrin repeat domain 55:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD55

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD55 Gene

No ASD Table

Relevant External Links for ANKRD55 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD55 Gene

mRNA expression in normal human tissues for ANKRD55 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKRD55 Gene

This gene is overexpressed in Whole Blood (x16.4), Brain - Hypothalamus (x5.3), and Testis (x4.9).

SOURCE GeneReport for Unigene cluster for ANKRD55 Gene Hs.436214

genes like me logo Genes that share expression patterns with ANKRD55: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ANKRD55 Gene

Orthologs for ANKRD55 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ANKRD55 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD55 35
  • 88.64 (n)
  • 89.46 (a)
ANKRD55 36
  • 89 (a)
(Canis familiaris)
Mammalia ANKRD55 35
  • 88.91 (n)
  • 89.4 (a)
ANKRD55 36
  • 89 (a)
(Mus musculus)
Mammalia Ankrd55 35
  • 84.56 (n)
  • 85.81 (a)
Ankrd55 16
Ankrd55 36
  • 84 (a)
(Pan troglodytes)
Mammalia ANKRD55 35
  • 99.4 (n)
  • 99.02 (a)
ANKRD55 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Ankrd55 35
  • 84.5 (n)
  • 86.32 (a)
(Monodelphis domestica)
Mammalia ANKRD55 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD55 36
  • 82 (a)
(Gallus gallus)
Aves ANKRD55 35
  • 70.08 (n)
  • 68.76 (a)
ANKRD55 36
  • 63 (a)
(Anolis carolinensis)
Reptilia ANKRD55 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd55 35
  • 67.69 (n)
  • 68.2 (a)
(Danio rerio)
Actinopterygii ankrd55 35
  • 63.9 (n)
  • 61.49 (a)
ankrd55 36
  • 54 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes AVO2 36
  • 22 (a)
Species with no ortholog for ANKRD55:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD55 Gene

Gene Tree for ANKRD55 (if available)
Gene Tree for ANKRD55 (if available)

Paralogs for ANKRD55 Gene

(6) SIMAP similar genes for ANKRD55 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ANKRD55: view

No data available for Paralogs for ANKRD55 Gene

Variants for ANKRD55 Gene

Sequence variations from dbSNP and Humsavar for ANKRD55 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
VAR_030283 -
VAR_055516 -

Structural Variations from Database of Genomic Variants (DGV) for ANKRD55 Gene

Variant ID Type Subtype PubMed ID
nsv329245 CNV Loss 16902084
nsv519960 CNV Loss 19592680
esv23752 CNV Loss 19812545
esv993277 CNV Deletion 20482838
nsv513238 CNV Loss 21212237
esv2730194 CNV Deletion 23290073
esv2677484 CNV Deletion 23128226
esv1152739 CNV Deletion 17803354
esv29252 CNV Loss 19812545
nsv881700 CNV Loss 21882294
esv268402 CNV Insertion 20981092
esv273609 CNV Insertion 20981092
esv1539040 CNV Insertion 17803354
esv2667446 CNV Deletion 23128226
esv269957 CNV Insertion 20981092
esv274436 CNV Insertion 20981092
esv274955 CNV Loss 21479260

Variation tolerance for ANKRD55 Gene

Residual Variation Intolerance Score: 27.09% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.66; 45.74% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD55 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD55 Gene

Disorders for ANKRD55 Gene

MalaCards: The human disease database

(2) MalaCards diseases for ANKRD55 Gene - From: Orphanet

Disorder Aliases PubMed IDs
polyarticular onset juvenile idiopathic arthritis
  • juvenile polyarthritis rheumatoid factor negative
oligoarticular juvenile arthritis
  • pauciarticular chronic arthritis
- elite association

Relevant External Links for ANKRD55

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ANKRD55: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ANKRD55 Gene

Publications for ANKRD55 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (PMID: 23535033) Sherva R. … Green R.C. (Alzheimers Dement 2014) 67
  3. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers. (PMID: 23382691) Lauc G. … Rudan I. (PLoS Genet. 2013) 67
  4. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. (PMID: 23263486) KAPttgen A. … Gieger C. (Nat. Genet. 2013) 67
  5. Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased I^-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort. (PMID: 23457408) Harder M.N. … Pedersen O. (J. Clin. Endocrinol. Metab. 2013) 67

Products for ANKRD55 Gene

Sources for ANKRD55 Gene

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