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Aliases for ANKRD49 Gene

Aliases for ANKRD49 Gene

  • Ankyrin Repeat Domain 49 2 3
  • Fetal Globin-Inducing Factor 3 4
  • FGIF 3 4
  • Ankyrin Repeat Domain-Containing Protein 49 3
  • GBIF 3

External Ids for ANKRD49 Gene

Summaries for ANKRD49 Gene

GeneCards Summary for ANKRD49 Gene

ANKRD49 (Ankyrin Repeat Domain 49) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD49 Gene

Genomics for ANKRD49 Gene

Genomic Location for ANKRD49 Gene

Start:
94,493,629 bp from pter
End:
94,499,583 bp from pter
Size:
5,955 bases
Orientation:
Plus strand

Genomic View for ANKRD49 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD49 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD49 Gene

Regulatory Elements for ANKRD49 Gene

Proteins for ANKRD49 Gene

  • Protein details for ANKRD49 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WVL7-ANR49_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 49
    Protein Accession:
    Q8WVL7
    Secondary Accessions:
    • Q8NDF2
    • Q96JE5
    • Q9NXK7

    Protein attributes for ANKRD49 Gene

    Size:
    239 amino acids
    Molecular mass:
    27290 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD49 Gene

Proteomics data for ANKRD49 Gene at MOPED

Post-translational modifications for ANKRD49 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ANKRD49 Gene

Domains for ANKRD49 Gene

Gene Families for ANKRD49 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD49 Gene

UniProtKB/Swiss-Prot:

ANR49_HUMAN
Similarity:
  • Contains 4 ANK repeats.:
    • Q8WVL7
genes like me logo Genes that share domains with ANKRD49: view

Function for ANKRD49 Gene

Gene Ontology (GO) - Molecular Function for ANKRD49 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25036637
genes like me logo Genes that share ontologies with ANKRD49: view

Phenotypes for ANKRD49 Gene

genes like me logo Genes that share phenotypes with ANKRD49: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKRD49 Gene

Localization for ANKRD49 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD49 Gene COMPARTMENTS Subcellular localization image for ANKRD49 gene
Compartment Confidence
nucleus 4
cytosol 3

Gene Ontology (GO) - Cellular Components for ANKRD49 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IC 16131492
genes like me logo Genes that share ontologies with ANKRD49: view

Pathways for ANKRD49 Gene

SuperPathways for ANKRD49 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD49 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045893 positive regulation of transcription, DNA-templated IDA 11162141
genes like me logo Genes that share ontologies with ANKRD49: view

No data available for Pathways by source for ANKRD49 Gene

Transcripts for ANKRD49 Gene

Unigene Clusters for ANKRD49 Gene

Ankyrin repeat domain 49:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD49 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f
SP1: - - - -
SP2: -
SP3:
SP4: - - - - - -
SP5: - - - -
SP6: - - -
SP7: - -
SP8:

Relevant External Links for ANKRD49 Gene

GeneLoc Exon Structure for
ANKRD49
ECgene alternative splicing isoforms for
ANKRD49

Expression for ANKRD49 Gene

mRNA expression in normal human tissues for ANKRD49 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ANKRD49 Gene

SOURCE GeneReport for Unigene cluster for ANKRD49 Gene Hs.29052

mRNA Expression by UniProt/SwissProt for ANKRD49 Gene

Q8WVL7-ANR49_HUMAN
Tissue specificity: Widely expressed in fetus, at a high level in fetal liver, brain and lung.
genes like me logo Genes that share expressions with ANKRD49: view

Orthologs for ANKRD49 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD49 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD49 36
  • 99.3 (n)
  • 99.58 (a)
ANKRD49 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ANKRD49 36
  • 89.08 (n)
  • 90.34 (a)
ANKRD49 37
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD49 36
  • 90.48 (n)
  • 93.28 (a)
ANKRD49 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd49 36
  • 88.66 (n)
  • 87.82 (a)
Ankrd49 16
Ankrd49 37
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKRD49 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD49 37
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd49 36
  • 86.64 (n)
  • 85.65 (a)
chicken
(Gallus gallus)
Aves ANKRD49 36
  • 74.22 (n)
  • 72.65 (a)
ANKRD49 37
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD49 37
  • 72 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ankrd49 36
  • 55.35 (n)
  • 55.81 (a)
ankrd49 37
  • 55 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007813 36
  • 50.25 (n)
  • 40.1 (a)
fruit fly
(Drosophila melanogaster)
Insecta l(2)35Be 36
  • 52.26 (n)
  • 45.68 (a)
l(2)35Be 37
  • 38 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F26F4.12 36
  • 47.68 (n)
  • 42.42 (a)
F26F4.12 37
  • 32 (a)
OneToOne
Species with no ortholog for ANKRD49:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ANKRD49 Gene

ENSEMBL:
Gene Tree for ANKRD49 (if available)
TreeFam:
Gene Tree for ANKRD49 (if available)

Paralogs for ANKRD49 Gene

Selected SIMAP similar genes for ANKRD49 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ANKRD49 Gene

genes like me logo Genes that share paralogs with ANKRD49: view

No data available for Paralogs for ANKRD49 Gene

Variants for ANKRD49 Gene

Sequence variations from dbSNP and Humsavar for ANKRD49 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs518640 -- 94,499,717(-) CACAG(A/G)GGGGC downstream-variant-500B
rs540199 -- 94,496,499(+) AAACA(A/G)GAGTT intron-variant
rs640429 -- 94,499,414(-) CACTT(G/T)GCCTG utr-variant-3-prime
rs1046654 -- 94,498,681(+) ACTTT(A/G)ATGTC utr-variant-3-prime
rs2509943 -- 94,498,091(+) AGACT(C/G)CTTTC reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ANKRD49 Gene

Variant ID Type Subtype PubMed ID
esv2671948 CNV Deletion 23128226
nsv819611 CNV Loss 19587683

Relevant External Links for ANKRD49 Gene

HapMap Linkage Disequilibrium report
ANKRD49

Disorders for ANKRD49 Gene

Relevant External Links for ANKRD49

Genetic Association Database (GAD)
ANKRD49
Human Genome Epidemiology (HuGE) Navigator
ANKRD49
genes like me logo Genes that share disorders with ANKRD49: view

No data available for UniProtKB/Swiss-Prot for ANKRD49 Gene

Publications for ANKRD49 Gene

  1. Cloning and characterization of a potential transcriptional activator of human gamma-globin genes. (PMID: 11162141) Yang Y. … Stamatoyannopoulos G. (Blood Cells Mol. Dis. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 49
  5. {gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice. (PMID: 16131492) Blau C.A. … Peterson K.R. (J. Biol. Chem. 2005) 3 23

Products for ANKRD49 Gene

  • antibodies-online proteins for ANKRD49
  • antibodies-online antibodies for ANKRD49
  • antibodies-online kits for ANKRD49

Sources for ANKRD49 Gene

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