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ANKRD46 Gene

protein-coding   GIFtS: 45
GCID: GC08M101522

Ankyrin Repeat Domain 46

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat Domain 461 2
Ankyrin Repeat Small Protein2 3
ANK-S2 3
GENX-1152792
Ankyrin Repeat Domain-Containing Protein 462

External Ids:    HGNC: 272291   Entrez Gene: 1575672   Ensembl: ENSG000001861067   UniProtKB: Q86W743   

Export aliases for ANKRD46 gene to outside databases

Previous GC identifers: GC08M101592 GC08M101602 GC08M096732


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ANKRD46 Gene:
This gene encodes a protein containing multiple ankyrin repeats. Ankyrin domains function in protein-protein
interactions in a variety of cellular processes. Alternative splicing results in multiple transcript variants.
(provided by RefSeq, Jun 2012)

GeneCards Summary for ANKRD46 Gene:
ANKRD46 (ankyrin repeat domain 46) is a protein-coding gene. Diseases associated with ANKRD46 include duchenne muscular dystrophy, and muscular dystrophy. An important paralog of this gene is ANKRD63.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ANKRD46 gene promoter:
         AP-1   AML1a   p300   RelA   E4BP4   NF-kappaB   c-Myb   FOXO1a   NF-kappaB1   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidANKRD46 promoter sequence
   Search Chromatin IP Primers for ANKRD46

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ANKRD46


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q22.2   Ensembl cytogenetic band:  8q22.2   HGNC cytogenetic band: 8q22.3

ANKRD46 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ANKRD46 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M101522:  view genomic region     (about GC identifiers)

Start:
101,521,980 bp from pter      End:
101,572,012 bp from pter
Size:
50,033 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ANR46_HUMAN, Q86W74 (See protein sequence)
Recommended Name: Ankyrin repeat domain-containing protein 46  
Size: 232 amino acids; 25967 Da
Secondary accessions: Q6P9B7
Alternative splicing: 2 isoforms:  Q86W74-1   Q86W74-2   

Explore the universe of human proteins at neXtProt for ANKRD46: NX_Q86W74

Explore proteomics data for ANKRD46 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys137
  • Modification sites at PhosphoSitePlus

  • See ANKRD46 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001257306.1  NP_001257307.1  NP_001257308.1  NP_940683.1  

    ENSEMBL proteins: 
     ENSP00000429015   ENSP00000335287   ENSP00000430056   ENSP00000428388   ENSP00000430827  
     ENSP00000351881   ENSP00000430357   ENSP00000430800   ENSP00000429647  

    ANKRD46 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ANKRD46

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    Abcam antibodies for ANKRD46
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    LSBio Antibodies in human, mouse, rat for ANKRD46

    ANKRD46 Assay Products:

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    Cloud-Clone Corp. ELISAs for ANKRD46
    Cloud-Clone Corp. CLIAs for ANKRD46


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing

    2 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q86W74

    ProtoNet protein and cluster: Q86W74

    1 Blocks protein domain: IPB002110 Ankyrin repeat signature

    UniProtKB/Swiss-Prot: ANR46_HUMAN, Q86W74
    Similarity: Contains 4 ANK repeats


    ANKRD46 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    ANKRD46 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ANKRD46
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ANKRD46
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    miRNA
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    miRTarBase miRNAs that target ANKRD46:
    hsa-mir-26b-5p (MIRT029288), hsa-mir-21-5p (MIRT005773), hsa-mir-375 (MIRT019737)

    Block miRNA regulation of human, mouse, rat ANKRD46 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ANKRD46 (see all 16):
    hsa-miR-98 hsa-miR-576-5p hsa-let-7d hsa-miR-7-2* hsa-miR-133b hsa-let-7c hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidANKRD46 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ANKRD46
    Predesigned siRNA for gene silencing in human, mouse, rat ANKRD46

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANKRD46 (NM_198401)
    Sino Biological Human cDNA Clone for ANKRD46
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANKRD46
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD46

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD46


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ANR46_HUMAN, Q86W74: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane2
    cytosol1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    ANKRD46 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ANKRD46
    Interactions:

        Search GeneGlobe Interaction Network for ANKRD46

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ANKRD46 (ENSP000003352874) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ANKRD46 (ANR46)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ANKRD46 gene (4 alternative transcripts): 
    NM_001270377.1  NM_001270378.1  NM_001270379.1  NM_198401.3  

    Unigene Cluster for ANKRD46:

    Ankyrin repeat domain 46
    Hs.530199  [show with all ESTs]
    Unigene Representative Sequence: NM_001270378
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000520552(uc003yjm.3) ENST00000335659 ENST00000519597(uc003yjo.1 uc003yjp.1)
    ENST00000520311(uc003yjn.1) ENST00000519316 ENST00000358990 ENST00000524072
    ENST00000523000 ENST00000521345 ENST00000520713 ENST00000524319(uc003yjq.4)

    miRNA
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    Block miRNA regulation of human, mouse, rat ANKRD46 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ANKRD46 (see all 16):
    hsa-miR-98 hsa-miR-576-5p hsa-let-7d hsa-miR-7-2* hsa-miR-133b hsa-let-7c hsa-let-7i hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidANKRD46 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ANKRD46
    Predesigned siRNA for gene silencing in human, mouse, rat ANKRD46
    Clone
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    OriGene clones in human, mouse for ANKRD46 (see all 6)
    OriGene ORF clones in mouse, rat for ANKRD46
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ANKRD46 (NM_198401)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ANKRD46
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD46
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ANKRD46
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ANKRD46
      QuantiTect SYBR Green Assays in human, mouse, rat ANKRD46
      QuantiFast Probe-based Assays in human, mouse, rat ANKRD46

    Additional mRNA sequence: 

    AB077205.1 AK095235.1 AL832842.1 BC015811.1 BC035087.1 BC050396.1 BC060843.1 U79297.1 

    9 DOTS entries:

    DT.100767657  DT.316456  DT.95262635  DT.91684283  DT.91640713  DT.91902091  DT.97837676  DT.121487472 
    DT.97860489 

    Selected AceView cDNA sequences (see all 194):

    CK904904 AA843912 BM726812 BM721039 BE300868 BX387059 BC009500 AA360435 
    CR607125 AI091557 BM828907 BU849608 BX434780 AL546194 F09828 F12804 
    AL561435 AI676209 AA234889 AI521506 BX440763 AW629831 AL832842 BC050396 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD46 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10
    SP1:                    -     -     -     -                                                   
    SP2:                    -     -     -     -           -                             -         
    SP3:                    -     -     -     -           -                                       
    SP4:                                -     -           -                                       
    SP5:                    -     -     -     -     -     -                                       


    ECgene alternative splicing isoforms for ANKRD46

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ANKRD46 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCTTTATC
    ANKRD46 Expression
    About this image

    ANKRD46 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ANKRD46 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.530199
        Custom PCR Arrays for ANKRD46
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD46

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ANKRD46 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ankrd461 , 5 ankyrin repeat domain 461, 5 87.72(n)1
    97.81(a)1
      15 (14.47 cM)5
    688391  NM_175134.41  NP_780343.11 
     364776685 
    chicken
    (Gallus gallus)
    Aves ANKRD461 ankyrin repeat domain 46 82.89(n)
    99.12(a)
      426304  XM_004939977.1  XP_004940034.1 
    lizard
    (Anolis carolinensis)
    Reptilia ANKRD466
    ankyrin repeat domain 46
    92(a)
    1 ↔ 1
    GL343394.1(108681-116665)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.88862 Xenopus laevis transcribed sequence with weak similarity more 79.98(n)    BJ029022.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.187232 Danio rerio hypothetical protein LOC157567-like protein more 76.02(n)    AY391435.1 


    ENSEMBL Gene Tree for ANKRD46 (if available)
    TreeFam Gene Tree for ANKRD46 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ANKRD46 gene
    ANKRD632  
    16 SIMAP similar genes for ANKRD46 using alignment to 6 protein entries:     ANR46_HUMAN (see all proteins):
    RAI14    PPP1R12A    GLS2    PPP1R12C    INVS    AGAP8
    ANKRD29    ANKRD44    ASB16    ASB8    TANC2    AGAP1
    ANKRD54    ANKRD6    FPGT-TNNI3K    IkBa

    ANKRD46 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ANKRD46 (see all 968)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1885734211,2
    --101521492(+) AGGCCA/GGGCCC 1 -- ds50010--------
    rs1918746321,2
    --101521707(+) AGGGAG/TCAACA 1 -- ds50010--------
    rs1839065291,2
    --101521708(+) GGGAGC/TAACAT 1 -- ds50010--------
    rs1903873621,2
    --101521964(+) AGAAAC/TGAAAA 1 -- ds50010--------
    rs1815293211,2
    --101522048(+) GCCTGA/GTACTT 1 -- ut310--------
    rs1875665421,2
    C--101522074(+) GGCAGC/GAGACA 1 -- ut310--------
    rs1901995991,2
    --101522135(+) GTCACA/GGAGAG 1 -- ut310--------
    rs790539981,2
    C--101522153(+) GGGAA-/GGGGGG 1 -- ut310--------
    rs1396698781,2
    --101522467(+) TTTCAA/GACACC 1 -- ut310--------
    rs78186181,2
    C,F,H--101522474(+) CACCAC/TGGCAG 1 -- ut31 ese310Minor allele frequency- T:0.05NS EA NA WA 1210

    HapMap Linkage Disequilibrium report for ANKRD46 (101521980 - 101572012 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ANKRD46: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ANKRD46
    DNA2.0 Custom Variant and Variant Library Synthesis for ANKRD46

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for ANKRD46:    
    About MalaCards
    duchenne muscular dystrophy    muscular dystrophy    breast cancer


    ANKRD46 for disorders           About GeneDecksing


    Export disorders for ANKRD46 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ANKRD46 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with ANKRD46)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    4. Identification of genes with a correlation between copy number and expression in gastric cancer. (PubMed id 22559327)1 Cheng L....Zhang Q. (BMC Med Genomics 2012)
    5. Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth. (PubMed id 21219636)1 Yan L.X....Shao J.Y. (Breast Cancer Res. 2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 157567 HGNC: 27229 AceView: LOC157567 Ensembl:ENSG00000186106 euGenes: HUgn157567
    ECgene: ANKRD46 H-InvDB: ANKRD46

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ANKRD46 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ANKRD46 gene:
    Search GeneIP for patents involving ANKRD46

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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