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Aliases for ANKRD45 Gene

Aliases for ANKRD45 Gene

  • Ankyrin Repeat Domain 45 2 3 5
  • Cancer/Testis Antigen 117 2 3
  • CT117 3

External Ids for ANKRD45 Gene

Previous GeneCards Identifiers for ANKRD45 Gene

  • GC01M170310
  • GC01M171844
  • GC01M144805

Summaries for ANKRD45 Gene

GeneCards Summary for ANKRD45 Gene

ANKRD45 (Ankyrin Repeat Domain 45) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD45 Gene

Genomics for ANKRD45 Gene

Regulatory Elements for ANKRD45 Gene

Enhancers for ANKRD45 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ANKRD45 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ANKRD45 gene promoter:

Genomic Location for ANKRD45 Gene

Chromosome:
1
Start:
173,608,336 bp from pter
End:
173,705,267 bp from pter
Size:
96,932 bases
Orientation:
Minus strand

Genomic View for ANKRD45 Gene

Genes around ANKRD45 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD45 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD45 Gene

Proteins for ANKRD45 Gene

  • Protein details for ANKRD45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TZF3-ANR45_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 45
    Protein Accession:
    Q5TZF3
    Secondary Accessions:
    • A1A4G2
    • Q6ZST1

    Protein attributes for ANKRD45 Gene

    Size:
    282 amino acids
    Molecular mass:
    31810 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD45 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ANKRD45 Gene

Proteomics data for ANKRD45 Gene at MOPED

Post-translational modifications for ANKRD45 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD45 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD45 Gene

Domains & Families for ANKRD45 Gene

Gene Families for ANKRD45 Gene

Protein Domains for ANKRD45 Gene

Suggested Antigen Peptide Sequences for ANKRD45 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5TZF3

UniProtKB/Swiss-Prot:

ANR45_HUMAN :
  • Contains 2 ANK repeats.
Similarity:
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with ANKRD45: view

Function for ANKRD45 Gene

genes like me logo Genes that share phenotypes with ANKRD45: view

Animal Model Products

CRISPR Products

miRNA for ANKRD45 Gene

miRTarBase miRNAs that target ANKRD45

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD45 Gene

Localization for ANKRD45 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD45 Gene COMPARTMENTS Subcellular localization image for ANKRD45 gene
Compartment Confidence
cytosol 4
nucleus 3
cytoskeleton 2
golgi apparatus 2
plasma membrane 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ANKRD45 Gene

Pathways & Interactions for ANKRD45 Gene

SuperPathways for ANKRD45 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD45 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ANKRD45 Gene

Drugs & Compounds for ANKRD45 Gene

No Compound Related Data Available

Transcripts for ANKRD45 Gene

mRNA/cDNA for ANKRD45 Gene

Unigene Clusters for ANKRD45 Gene

Ankyrin repeat domain 45:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD45 Gene

No ASD Table

Relevant External Links for ANKRD45 Gene

GeneLoc Exon Structure for
ANKRD45
ECgene alternative splicing isoforms for
ANKRD45

Expression for ANKRD45 Gene

mRNA expression in normal human tissues for ANKRD45 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKRD45 Gene

This gene is overexpressed in Testis (x9.4), Brain - Nucleus accumbens (basal ganglia) (x5.9), and Brain - Caudate (basal ganglia) (x5.7).

Protein differential expression in normal tissues from HIPED for ANKRD45 Gene

This gene is overexpressed in Monocytes (30.7), Testis (13.9), Prostate (13.8), and Retina (8.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ANKRD45 Gene



SOURCE GeneReport for Unigene cluster for ANKRD45 Gene Hs.130054

genes like me logo Genes that share expression patterns with ANKRD45: view

Protein tissue co-expression partners for ANKRD45 Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for ANKRD45 Gene

Orthologs for ANKRD45 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ANKRD45 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ANKRD45 35
  • 89.15 (n)
  • 88.89 (a)
ANKRD45 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD45 35
  • 91.07 (n)
  • 91.32 (a)
ANKRD45 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd45 35
  • 81.4 (n)
  • 79.75 (a)
Ankrd45 16
Ankrd45 36
  • 69 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ANKRD45 35
  • 99.75 (n)
  • 99.62 (a)
ANKRD45 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd45 35
  • 80.84 (n)
  • 78.35 (a)
oppossum
(Monodelphis domestica)
Mammalia ANKRD45 36
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD45 36
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd45 35
  • 59.8 (n)
  • 48.53 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.18865 35
zebrafish
(Danio rerio)
Actinopterygii ankrd45 35
  • 55.01 (n)
  • 45.81 (a)
ankrd45 36
  • 41 (a)
OneToOne
barley
(Hordeum vulgare)
Liliopsida Hv.7279 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
OneToOne
Species with no ortholog for ANKRD45:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD45 Gene

ENSEMBL:
Gene Tree for ANKRD45 (if available)
TreeFam:
Gene Tree for ANKRD45 (if available)

Paralogs for ANKRD45 Gene

No data available for Paralogs for ANKRD45 Gene

Variants for ANKRD45 Gene

Sequence variations from dbSNP and Humsavar for ANKRD45 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs2126126 -- 173,684,715(+) CAACA(C/T)TGAGT intron-variant
rs6659070 -- 173,692,113(+) aggta(A/G)tcgaa intron-variant
rs7412978 -- 173,699,602(+) aaaag(G/T)cctga intron-variant
rs6699555 -- 173,692,665(+) TAAAC(A/G)GTGAG intron-variant
rs6681766 -- 173,703,660(+) CAAAC(A/G)TAGGT intron-variant

Variation tolerance for ANKRD45 Gene

Residual Variation Intolerance Score: 80.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.91; 48.84% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ANKRD45 Gene

Disorders for ANKRD45 Gene

Relevant External Links for ANKRD45

Genetic Association Database (GAD)
ANKRD45
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD45

No disorders were found for ANKRD45 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD45 Gene

Publications for ANKRD45 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ANKRD45 Gene

Sources for ANKRD45 Gene

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