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Aliases for ANKRD42 Gene

Aliases for ANKRD42 Gene

  • Ankyrin Repeat Domain 42 2 3
  • Protein Phosphatase 1, Regulatory Subunit 79 3
  • Ankyrin Repeat Domain-Containing Protein 42 3
  • Several Ankyrin Repeat Protein 3
  • Protein Phosphatase 1 2
  • Regulatory Subunit 79 2
  • PPP1R79 3
  • SARP 3

External Ids for ANKRD42 Gene

Previous GeneCards Identifiers for ANKRD42 Gene

  • GC11P082583
  • GC11P082904
  • GC11P079202

Summaries for ANKRD42 Gene

GeneCards Summary for ANKRD42 Gene

ANKRD42 (Ankyrin Repeat Domain 42) is a Protein Coding gene. GO annotations related to this gene include NF-kappaB binding. An important paralog of this gene is ASB7.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD42 Gene

Genomics for ANKRD42 Gene

Regulatory Elements for ANKRD42 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ANKRD42 Gene

83,193,712 bp from pter
83,260,694 bp from pter
66,983 bases
Plus strand

Genomic View for ANKRD42 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD42 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD42 Gene

Proteins for ANKRD42 Gene

  • Protein details for ANKRD42 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 42
    Protein Accession:
    Secondary Accessions:
    • Q49A49

    Protein attributes for ANKRD42 Gene

    389 amino acids
    Molecular mass:
    43052 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ANKRD42 Gene


neXtProt entry for ANKRD42 Gene

Proteomics data for ANKRD42 Gene at MOPED

Post-translational modifications for ANKRD42 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ANKRD42 Gene

Domains for ANKRD42 Gene

Gene Families for ANKRD42 Gene

  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD42 Gene

Suggested Antigen Peptide Sequences for ANKRD42 Gene

Graphical View of Domain Structure for InterPro Entry



  • Q8N9B4
  • Contains 9 ANK repeats.
genes like me logo Genes that share domains with ANKRD42: view

Function for ANKRD42 Gene

Gene Ontology (GO) - Molecular Function for ANKRD42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003735 structural constituent of ribosome --
GO:0005515 protein binding --
GO:0051059 NF-kappaB binding IEA --
genes like me logo Genes that share ontologies with ANKRD42: view

Animal Model Products

CRISPR Products

miRNA for ANKRD42 Gene

miRTarBase miRNAs that target ANKRD42

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ANKRD42 Gene

Localization for ANKRD42 Gene

Subcellular locations from

Jensen Localization Image for ANKRD42 Gene COMPARTMENTS Subcellular localization image for ANKRD42 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ANKRD42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005840 ribosome --
genes like me logo Genes that share ontologies with ANKRD42: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ANKRD42 Gene

Pathways for ANKRD42 Gene

SuperPathways for ANKRD42 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD42 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006412 translation --
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity --
GO:0051092 positive regulation of NF-kappaB transcription factor activity IEA --
GO:1900017 positive regulation of cytokine production involved in inflammatory response IEA --
genes like me logo Genes that share ontologies with ANKRD42: view

No data available for Pathways by source for ANKRD42 Gene

Transcripts for ANKRD42 Gene

Unigene Clusters for ANKRD42 Gene

Ankyrin repeat domain 42:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ANKRD42

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD42 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP1: - - - -
SP3: -
SP4: - -

Relevant External Links for ANKRD42 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD42 Gene

mRNA expression in normal human tissues for ANKRD42 Gene

Protein differential expression in normal tissues for ANKRD42 Gene

This gene is overexpressed in Pancreas (36.5) and Bone (27.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ANKRD42 Gene

SOURCE GeneReport for Unigene cluster for ANKRD42 Gene Hs.503438

genes like me logo Genes that share expressions with ANKRD42: view

Expression partners for ANKRD42 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ANKRD42 Gene

Orthologs for ANKRD42 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ANKRD42 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD42 35
  • 89.01 (n)
  • 88.38 (a)
ANKRD42 36
  • 42 (a)
(Canis familiaris)
Mammalia ANKRD42 35
  • 87.63 (n)
  • 86.34 (a)
ANKRD42 36
  • 89 (a)
(Mus musculus)
Mammalia Ankrd42 35
  • 84.82 (n)
  • 83.2 (a)
Ankrd42 16
Ankrd42 36
  • 60 (a)
(Pan troglodytes)
Mammalia ANKRD42 35
  • 99.64 (n)
  • 100 (a)
ANKRD42 36
  • 71 (a)
(Rattus norvegicus)
Mammalia Ankrd42 35
  • 85.14 (n)
  • 83.7 (a)
(Monodelphis domestica)
Mammalia ANKRD42 36
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia ANKRD42 36
  • 46 (a)
(Gallus gallus)
Aves ANKRD42 35
  • 68.96 (n)
  • 66.76 (a)
ANKRD42 36
  • 45 (a)
(Anolis carolinensis)
Reptilia ANKRD42 36
  • 43 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd42 35
  • 65.74 (n)
  • 65.28 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9121 36
  • 11 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NAS6 36
  • 21 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7381 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 38 (a)
Species with no ortholog for ANKRD42:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ANKRD42 Gene

Gene Tree for ANKRD42 (if available)
Gene Tree for ANKRD42 (if available)

Paralogs for ANKRD42 Gene

Paralogs for ANKRD42 Gene

genes like me logo Genes that share paralogs with ANKRD42: view

Variants for ANKRD42 Gene

Sequence variations from dbSNP and Humsavar for ANKRD42 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs472309 -- 83,217,476(+) tcgtc(A/G)gatag intron-variant
rs472431 -- 83,217,527(+) aactg(A/T)gaagg intron-variant
rs473622 -- 83,251,944(+) gatta(C/T)atgaa intron-variant
rs474747 -- 83,252,106(+) cttgt(A/G)taggc intron-variant
rs477105 -- 83,202,015(+) gtcaa(C/T)gttgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD42 Gene

Variant ID Type Subtype PubMed ID
esv33531 CNV Loss 17666407

Relevant External Links for ANKRD42 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD42 Gene

Disorders for ANKRD42 Gene

No disorders were found for ANKRD42 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ANKRD42 Gene

Publications for ANKRD42 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. SARP, a new alternatively spliced protein phosphatase 1 and DNA interacting protein. (PMID: 17123353) Browne G.J. … da Cruz E Silva E.F. (Biochem. J. 2007) 3
  4. Identification of the human testis protein phosphatase 1 interactome. (PMID: 21382349) Fardilha M. … da Cruz e Silva E.F. (Biochem. Pharmacol. 2011) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for ANKRD42 Gene

Sources for ANKRD42 Gene

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