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Aliases for ANKRD40 Gene

Aliases for ANKRD40 Gene

  • Ankyrin Repeat Domain 40 2 3

External Ids for ANKRD40 Gene

Summaries for ANKRD40 Gene

GeneCards Summary for ANKRD40 Gene

ANKRD40 (Ankyrin Repeat Domain 40) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD40 Gene

Genomics for ANKRD40 Gene

Genomic Location for ANKRD40 Gene

Start:
50,693,190 bp from pter
End:
50,707,924 bp from pter
Size:
14,735 bases
Orientation:
Minus strand

Genomic View for ANKRD40 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD40 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD40 Gene

Regulatory Elements for ANKRD40 Gene

Proteins for ANKRD40 Gene

  • Protein details for ANKRD40 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AI12-ANR40_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 40
    Protein Accession:
    Q6AI12
    Secondary Accessions:
    • Q96E32

    Protein attributes for ANKRD40 Gene

    Size:
    368 amino acids
    Molecular mass:
    41088 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD40 Gene

Proteomics data for ANKRD40 Gene at MOPED

Post-translational modifications for ANKRD40 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD40 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD40 Gene

Domains for ANKRD40 Gene

Gene Families for ANKRD40 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD40 Gene

Suggested Antigen Peptide Sequences for ANKRD40 Gene

Graphical View of Domain Structure for InterPro Entry

Q6AI12

UniProtKB/Swiss-Prot:

ANR40_HUMAN
Similarity:
  • Contains 2 ANK repeats.:
    • Q6AI12
genes like me logo Genes that share domains with ANKRD40: view

Function for ANKRD40 Gene

Gene Ontology (GO) - Molecular Function for ANKRD40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ANKRD40: view

miRNA for ANKRD40 Gene

miRTarBase miRNAs that target ANKRD40

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ANKRD40 Gene

Localization for ANKRD40 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD40 Gene COMPARTMENTS Subcellular localization image for ANKRD40 gene
Compartment Confidence
cytosol 3
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for ANKRD40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with ANKRD40: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ANKRD40 Gene

Pathways for ANKRD40 Gene

SuperPathways for ANKRD40 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ANKRD40: view

No data available for Pathways by source for ANKRD40 Gene

Transcripts for ANKRD40 Gene

mRNA/cDNA for ANKRD40 Gene

Unigene Clusters for ANKRD40 Gene

Ankyrin repeat domain 40:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD40 Gene

No ASD Table

Relevant External Links for ANKRD40 Gene

GeneLoc Exon Structure for
ANKRD40
ECgene alternative splicing isoforms for
ANKRD40

Expression for ANKRD40 Gene

mRNA expression in normal human tissues for ANKRD40 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ANKRD40 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (5.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ANKRD40 Gene

SOURCE GeneReport for Unigene cluster for ANKRD40 Gene Hs.463426

genes like me logo Genes that share expressions with ANKRD40: view

No data available for mRNA Expression by UniProt/SwissProt for ANKRD40 Gene

Orthologs for ANKRD40 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD40 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD40 35
  • 99.73 (n)
  • 99.46 (a)
ANKRD40 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ANKRD40 35
  • 92.97 (n)
  • 95.89 (a)
ANKRD40 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD40 35
  • 91.03 (n)
  • 93.96 (a)
ANKRD40 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd40 35
  • 89.99 (n)
  • 93.39 (a)
Ankrd40 16
Ankrd40 36
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKRD40 36
  • 87 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD40 36
  • 68 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd40 35
  • 90.36 (n)
  • 93.39 (a)
chicken
(Gallus gallus)
Aves ANKRD40 35
  • 59.3 (n)
  • 58.14 (a)
ANKRD40 36
  • 56 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD40 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd40 35
  • 61.64 (n)
  • 58.58 (a)
zebrafish
(Danio rerio)
Actinopterygii ankrd40 36
  • 48 (a)
OneToOne
LOC100005118 35
  • 60.42 (n)
  • 59.65 (a)
worm
(Caenorhabditis elegans)
Secernentea R31.2 36
  • 14 (a)
OneToOne
Species with no ortholog for ANKRD40:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ANKRD40 Gene

ENSEMBL:
Gene Tree for ANKRD40 (if available)
TreeFam:
Gene Tree for ANKRD40 (if available)

Paralogs for ANKRD40 Gene

Pseudogenes.org Pseudogenes for ANKRD40 Gene

genes like me logo Genes that share paralogs with ANKRD40: view

No data available for Paralogs for ANKRD40 Gene

Variants for ANKRD40 Gene

Sequence variations from dbSNP and Humsavar for ANKRD40 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs8196 -- 50,693,598(-) GGGCA(C/T)GTTCT utr-variant-3-prime
rs9455 -- 50,693,774(-) TAAAA(A/C)AGTTA utr-variant-3-prime
rs14882 -- 50,693,258(-) TTTTT(C/T)TTTGT utr-variant-3-prime
rs1990333 -- 50,698,984(+) aaaat(A/C)caaaa intron-variant
rs2286650 -- 50,700,937(+) TAACT(C/T)AACCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD40 Gene

Variant ID Type Subtype PubMed ID
dgv42n68 CNV Loss 17160897
nsv111922 CNV Loss 16902084
esv2716039 CNV Deletion 23290073
esv2242752 CNV Deletion 18987734

Relevant External Links for ANKRD40 Gene

HapMap Linkage Disequilibrium report
ANKRD40

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD40 Gene

Disorders for ANKRD40 Gene

Relevant External Links for ANKRD40

Genetic Association Database (GAD)
ANKRD40
Human Genome Epidemiology (HuGE) Navigator
ANKRD40
genes like me logo Genes that share disorders with ANKRD40: view

No data available for UniProtKB/Swiss-Prot for ANKRD40 Gene

Publications for ANKRD40 Gene

  1. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for ANKRD40 Gene

Sources for ANKRD40 Gene

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