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Aliases for ANKRD39 Gene

Aliases for ANKRD39 Gene

  • Ankyrin Repeat Domain 39 2 3 5

External Ids for ANKRD39 Gene

Previous GeneCards Identifiers for ANKRD39 Gene

  • GC02M096936
  • GC02M096865
  • GC02M097502
  • GC02M091473

Summaries for ANKRD39 Gene

GeneCards Summary for ANKRD39 Gene

ANKRD39 (Ankyrin Repeat Domain 39) is a Protein Coding gene. An important paralog of this gene is GABPB1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD39 Gene

Genomics for ANKRD39 Gene

Regulatory Elements for ANKRD39 Gene

Enhancers for ANKRD39 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F096905 1.1 Ensembl ENCODE 13 -49.1 -49125 2.5 KLF1 MAZ SP3 MNT ZIC2 NR2F2 ZFHX2 GLIS2 SCRT2 GLIS1 FAM178B SEMA4C ANKRD23 ANKRD39 SNRNP200 LOC101927053
GH02F096861 0.2 Ensembl 0.8 -4.1 -4111 0.8 MLX ARID4B DMAP1 YY1 SLC30A9 PAF1 SP5 MXD4 MIER2 PPARG CNNM3 ANKRD39 SEMA4C
GH02F096856 0.5 ENCODE 0.8 -0.4 -420 3.7 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 STARD7-AS1 SNRNP200 LMAN2L ANKRD39 SEMA4C
GH02F096863 0.2 Ensembl 0.4 -5.0 -5006 0.2 ZNF362 ANKRD39 SEMA4C
GH02F096866 0.7 ENCODE 0.4 -10.8 -10791 5.3 HDGF PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 SLC30A9 ZNF143 ZNF263 FAM178B LMAN2L SNRNP200 GPAT2P2 LINC01125 ANKRD36B SEMA4C ANKRD39
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ANKRD39 on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD39 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000594823 195 2201 PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for ANKRD39 Gene

Chromosome:
2
Start:
96,836,611 bp from pter
End:
96,858,095 bp from pter
Size:
21,485 bases
Orientation:
Minus strand

Genomic View for ANKRD39 Gene

Genes around ANKRD39 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD39 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD39 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD39 Gene

Proteins for ANKRD39 Gene

  • Protein details for ANKRD39 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q53RE8-ANR39_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 39
    Protein Accession:
    Q53RE8
    Secondary Accessions:
    • Q59FU2
    • Q8N5X5
    • Q9P0S5

    Protein attributes for ANKRD39 Gene

    Size:
    183 amino acids
    Molecular mass:
    19651 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF36120.1; Type=Frameshift; Positions=172; Evidence={ECO:0000305}; Sequence=BAD92604.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ANKRD39 Gene

Post-translational modifications for ANKRD39 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ANKRD39 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD39 Gene

Domains & Families for ANKRD39 Gene

Gene Families for ANKRD39 Gene

Protein Domains for ANKRD39 Gene

Suggested Antigen Peptide Sequences for ANKRD39 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q53RE8

UniProtKB/Swiss-Prot:

ANR39_HUMAN :
  • Belongs to the ANKRD39 family.
  • Contains 4 ANK repeats.
Family:
  • Belongs to the ANKRD39 family.
Similarity:
  • Contains 4 ANK repeats.
genes like me logo Genes that share domains with ANKRD39: view

Function for ANKRD39 Gene

Gene Ontology (GO) - Molecular Function for ANKRD39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with ANKRD39: view
genes like me logo Genes that share phenotypes with ANKRD39: view

Animal Model Products

miRNA for ANKRD39 Gene

miRTarBase miRNAs that target ANKRD39

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD39 Gene

Localization for ANKRD39 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD39 Gene COMPARTMENTS Subcellular localization image for ANKRD39 gene
Compartment Confidence
cytosol 4
nucleus 3
extracellular 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ANKRD39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with ANKRD39: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ANKRD39 Gene

Pathways & Interactions for ANKRD39 Gene

SuperPathways for ANKRD39 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD39 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ANKRD39: view

No data available for Pathways by source and SIGNOR curated interactions for ANKRD39 Gene

Transcripts for ANKRD39 Gene

mRNA/cDNA for ANKRD39 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(177) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ANKRD39 Gene

Ankyrin repeat domain 39:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD39 Gene

No ASD Table

Relevant External Links for ANKRD39 Gene

GeneLoc Exon Structure for
ANKRD39
ECgene alternative splicing isoforms for
ANKRD39

Expression for ANKRD39 Gene

mRNA expression in normal human tissues for ANKRD39 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ANKRD39 Gene



NURSA nuclear receptor signaling pathways regulating expression of ANKRD39 Gene:

ANKRD39

SOURCE GeneReport for Unigene cluster for ANKRD39 Gene:

Hs.709507
genes like me logo Genes that share expression patterns with ANKRD39: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ANKRD39 Gene

Orthologs for ANKRD39 Gene

This gene was present in the common ancestor of animals.

Orthologs for ANKRD39 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD39 34 35
  • 99.82 (n)
cow
(Bos Taurus)
Mammalia ANKRD39 34 35
  • 88.52 (n)
dog
(Canis familiaris)
Mammalia ANKRD39 34 35
  • 87.07 (n)
mouse
(Mus musculus)
Mammalia Ankrd39 34 16 35
  • 87.07 (n)
rat
(Rattus norvegicus)
Mammalia Ankrd39 34
  • 86.34 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia ANKRD39 35
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ANKRD39 35
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd39 34
  • 58.81 (n)
Str.15021 34
zebrafish
(Danio rerio)
Actinopterygii ankrd39 34 35
  • 58.28 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG44001 34
  • 55.35 (n)
CG31919 35
  • 23 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009205 34
  • 50.57 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 43 (a)
OneToOne
Species where no ortholog for ANKRD39 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD39 Gene

ENSEMBL:
Gene Tree for ANKRD39 (if available)
TreeFam:
Gene Tree for ANKRD39 (if available)

Paralogs for ANKRD39 Gene

Paralogs for ANKRD39 Gene

(9) SIMAP similar genes for ANKRD39 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ANKRD39 Gene

genes like me logo Genes that share paralogs with ANKRD39: view

Variants for ANKRD39 Gene

Sequence variations from dbSNP and Humsavar for ANKRD39 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10188136 -- 96,850,693(+) aaaaa(A/C)aAAAA intron-variant
rs10203346 -- 96,851,500(+) tgccc(A/G)gcctg intron-variant
rs1043756 -- 96,859,896(-) GGGGA(A/G)AGAAG upstream-variant-2KB, utr-variant-3-prime
rs1043759 -- 96,859,887(-) AGGGA(A/G)AGGGT upstream-variant-2KB, utr-variant-3-prime
rs111443314 -- 96,852,088(+) CACCT(C/G)TAGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ANKRD39 Gene

Variant ID Type Subtype PubMed ID
dgv607e201 CNV deletion 23290073
esv3425717 CNV duplication 20981092
esv3591694 CNV loss 21293372
esv5003 OTHER complex 18987735
nsv1135873 CNV deletion 24896259
nsv526313 CNV loss 19592680

Variation tolerance for ANKRD39 Gene

Residual Variation Intolerance Score: 65.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.66; 14.06% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD39 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ANKRD39

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD39 Gene

Disorders for ANKRD39 Gene

Relevant External Links for ANKRD39

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ANKRD39

No disorders were found for ANKRD39 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD39 Gene

Publications for ANKRD39 Gene

  1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 2 3 4 64
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 3 64
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64

Products for ANKRD39 Gene

Sources for ANKRD39 Gene

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