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Aliases for ANKRD37 Gene

Aliases for ANKRD37 Gene

  • Ankyrin Repeat Domain 37 2 3
  • Low-Density Lipoprotein Receptor-Related Protein 2-Binding Protein 3 4
  • HLrp2bp 3 4
  • Low Density Lipoprotein Receptor-Related Protein Binding Protein 3
  • Ankyrin Repeat Domain-Containing Protein 37 3
  • Lrp2bp 3
  • LPR2BP 4

External Ids for ANKRD37 Gene

Summaries for ANKRD37 Gene

GeneCards Summary for ANKRD37 Gene

ANKRD37 (Ankyrin Repeat Domain 37) is a Protein Coding gene. An important paralog of this gene is ANKRD10.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD37 Gene

Genomics for ANKRD37 Gene

Genomic Location for ANKRD37 Gene

Start:
185,396,021 bp from pter
End:
185,400,628 bp from pter
Size:
4,608 bases
Orientation:
Plus strand

Genomic View for ANKRD37 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ANKRD37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD37 Gene

Regulatory Elements for ANKRD37 Gene

Proteins for ANKRD37 Gene

  • Protein details for ANKRD37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z713-ANR37_HUMAN
    Recommended name:
    Ankyrin repeat domain-containing protein 37
    Protein Accession:
    Q7Z713
    Secondary Accessions:

    Protein attributes for ANKRD37 Gene

    Size:
    158 amino acids
    Molecular mass:
    16872 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD37 Gene

Proteomics data for ANKRD37 Gene at MOPED

Post-translational modifications for ANKRD37 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys120 and Lys126

Other Protein References for ANKRD37 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD37 Gene

Domains for ANKRD37 Gene

Gene Families for ANKRD37 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing

Protein Domains for ANKRD37 Gene

UniProtKB/Swiss-Prot:

ANR37_HUMAN
Similarity:
  • Contains 3 ANK repeats.:
    • Q7Z713
genes like me logo Genes that share domains with ANKRD37: view

Function for ANKRD37 Gene

Gene Ontology (GO) - Molecular Function for ANKRD37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ANKRD37: view

Phenotypes for ANKRD37 Gene

GenomeRNAi human phenotypes for ANKRD37:
genes like me logo Genes that share phenotypes with ANKRD37: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ANKRD37 Gene

Localization for ANKRD37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ANKRD37 Gene

Nucleus. Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ANKRD37 Gene COMPARTMENTS Subcellular localization image for ANKRD37 gene
Compartment Confidence
nucleus 5
extracellular 2
cytosol 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ANKRD37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with ANKRD37: view

Pathways for ANKRD37 Gene

SuperPathways for ANKRD37 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD37 Gene

None

No data available for Pathways by source for ANKRD37 Gene

Transcripts for ANKRD37 Gene

Unigene Clusters for ANKRD37 Gene

Ankyrin repeat domain 37:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD37 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6
SP1: -
SP2:
SP3: - - - -
SP4: -
SP5: -

Relevant External Links for ANKRD37 Gene

GeneLoc Exon Structure for
ANKRD37
ECgene alternative splicing isoforms for
ANKRD37

Expression for ANKRD37 Gene

mRNA expression in normal human tissues for ANKRD37 Gene

SOURCE GeneReport for Unigene cluster for ANKRD37 Gene Hs.508154

mRNA Expression by UniProt/SwissProt for ANKRD37 Gene

Q7Z713-ANR37_HUMAN
Tissue specificity: Mainly expressed in testis, small intestine, colon, blood leukocytes and in pancreatic adenocarcinoma cells.
genes like me logo Genes that share expressions with ANKRD37: view

Orthologs for ANKRD37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD37 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ANKRD37 36
  • 98.95 (n)
  • 98.73 (a)
ANKRD37 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ANKRD37 36
  • 90.3 (n)
  • 87.97 (a)
ANKRD37 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ANKRD37 36
  • 87.76 (n)
  • 86.08 (a)
ANKRD37 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ankrd37 36
  • 78.9 (n)
  • 77.22 (a)
Ankrd37 16
Ankrd37 37
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ANKRD37 37
  • 72 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ankrd37 36
  • 80.8 (n)
  • 80.38 (a)
lizard
(Anolis carolinensis)
Reptilia ANKRD37 37
  • 36 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.8033 36
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd37 36
  • 64.48 (n)
  • 64.75 (a)
Str.10884 36
zebrafish
(Danio rerio)
Actinopterygii ankrd37 36
  • 58.13 (n)
  • 53.6 (a)
ankrd37 37
  • 41 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 24 (a)
OneToMany
Species with no ortholog for ANKRD37:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD37 Gene

ENSEMBL:
Gene Tree for ANKRD37 (if available)
TreeFam:
Gene Tree for ANKRD37 (if available)

Paralogs for ANKRD37 Gene

Paralogs for ANKRD37 Gene

Selected SIMAP similar genes for ANKRD37 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ANKRD37: view

Variants for ANKRD37 Gene

Sequence variations from dbSNP and Humsavar for ANKRD37 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs76073842 -- 185,398,925(+) CACCA(C/T)CTTAC intron-variant
rs112594372 -- 185,398,926(+) ACCAT(C/G)TTACC intron-variant
rs372070862 -- 185,399,031(+) TGAGT(A/G)AGTAT intron-variant
rs374073662 -- 185,398,922(+) ATGCA(C/T)CATCT intron-variant
rs374245519 -- 185,398,958(+) CTCCA(C/T)TACAC reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ANKRD37 Gene

Variant ID Type Subtype PubMed ID
nsv428456 CNV Gain+Loss 18775914
nsv881506 CNV Gain 21882294
dgv1724e1 CNV Complex 17122850

Relevant External Links for ANKRD37 Gene

HapMap Linkage Disequilibrium report
ANKRD37

Disorders for ANKRD37 Gene

No disorders were found for ANKRD37 Gene.

No data available for UniProtKB/Swiss-Prot for ANKRD37 Gene

Publications for ANKRD37 Gene

  1. Molecular cloning and characterization of a novel human gene containing 4 ankyrin repeat domains. (PMID: 15809689) Li J. … Mao Y. (Cell. Mol. Biol. Lett. 2005) 3 4 23
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. (PMID: 19491311) Benita Y. … Xavier R.J. (Nucleic Acids Res. 2009) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ANKRD37 Gene

Sources for ANKRD37 Gene

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