ANKRD37 Gene
protein-coding GIFtS: 46
GCID: GC04P186317
|
|
ankyrin repeat domain 37
| |
Aliases
for ANKRD37 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankyrin Repeat Domain 371 2 | | Ankyrin Repeat Domain-Containing Protein 372 | | Lrp2bp1 2 | | Low Density Lipoprotein Receptor-Related Protein Binding Protein2 | | Low-Density Lipoprotein Receptor-Related Protein 2-Binding Protein2 3 | | LPR2BP3 | | HLrp2bp1 | | |
Export aliases for ANKRD37 gene to outside databasesPrevious GC identifers: GC04P186693 GC04P186554 GC04P182071 |
Summaries
for ANKRD37 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ANKRD37 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ANKRD37 gene promoter:
CBF-C YY1 POU2F1 CBF-B CBF-A POU2F1b POU2F1a CP1A POU2F1c CBF(2)
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKRD37
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD37 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q35.1 Ensembl cytogenetic band: 4q35.1 HGNC cytogenetic band: 4q35.1ANKRD37 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P186317: view genomic region
(about GC identifiers)
Start:
|
186,317,175 bp from pter |
End:
|
186,321,782 bp from pter |
Size:
|
4,608 bases |
Orientation:
|
plus strand |
|
Proteins
for ANKRD37 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ANR37_HUMAN, Q7Z713 (See
protein sequence)Recommended Name: Ankyrin repeat domain-containing protein 37 Size: 158 amino acids; 16872 Da
Subcellular location: Nucleus. CytoplasmExplore the universe of human proteins at neXtProt for ANKRD37: NX_Q7Z713
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z713
ANKRD37 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_859077.1
ENSEMBL proteins: ENSP00000421529 ENSP00000335147 ENSP00000427192
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ANKRD37 for ontologies About GeneDecksing
ANKRD37 Antibody Products:
Assay Products for ANKRD37: |
Protein
Domains /
Families
for ANKRD37 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKRD37 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7Z713ProtoNet protein and cluster: Q7Z713 1 Blocks protein family: IPB002110 Ankyrin repeat signature
UniProtKB/Swiss-Prot: ANR37_HUMAN, Q7Z713Similarity: Contains 3 ANK repeats |
Function
for ANKRD37 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD37 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD37 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ANKRD37 (NM_181726) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKRD37 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD37 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD37 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
ANKRD37 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ANKRD37:
|
Pathways & Interactions
for ANKRD37 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD37
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ANKRD37 (ENSP000003351474) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ANKRD37 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANKRD37
Search CenterWatch for drugs/clinical trials and news about ANKRD37 / ANR37
|
Transcripts
for ANKRD37 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANKRD37 gene: NM_181726.2 Unigene Cluster for ANKRD37: Ankyrin repeat domain 37 Hs.508154 [show with all ESTs]Unigene Representative Sequence: AK1273956 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000507479 ENST00000507753 ENST00000335174(uc003ixm.3) ENST00000511393(uc011cks.2)
ENST00000511311 ENST00000506424
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD37 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD37 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ANKRD37 (NM_181726) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ANKRD37 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD37 |
Additional cDNA sequence: AK127395.1 AK303243.1 AY296056.1 BC088376.1 8 DOTS entries: DT.99928380 DT.100810742 DT.92440901 DT.97858856 DT.121224482 DT.100810754 DT.40129238 DT.121224610 24/107 AceView cDNA sequences (see all 107): AI937434 AW664874 AI216877 BM997127 AI797540 CA748553 AI375295 AI333984 AA961059 AA885898 W23609 AA886870 R81196 CA450084 AI950798 BQ575105 BM696704 BM716455 AA869002 BM987064 AI382103 AA934911 AW610097 CA391165
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD37 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for ANKRD37
|
Expression
for ANKRD37 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKRD37 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTATAATAT
About this image
See ANKRD37 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANKRD37
SOURCE GeneReport for Unigene cluster: Hs.508154
UniProtKB/Swiss-Prot: ANR37_HUMAN, Q7Z713Tissue specificity: Mainly expressed in testis, small intestine, colon, blood leukocytes and in pancreaticadenocarcinoma cells
SABiosciences Expression via Pathway-Focused PCR Array including ANKRD37:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKRD37
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ANKRD37 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD37 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD37 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD37 |
Orthologs
for ANKRD37 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ANKRD37 gene from 3/12 species (see all 12) About this table
ENSEMBL Gene Tree for ANKRD37 (if available)
TreeFam Gene Tree for ANKRD37 (if available) |
Paralogs
for ANKRD37 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANKRD37 gene
- ANKRD102
1 SIMAP similar gene for ANKRD37 using alignment to 3 protein entries: ANR37_HUMAN (see all proteins):ANKRD10
ANKRD37 for paralogs About GeneDecksing
|
Genomic Variants
for ANKRD37 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ANKRD37
1 CNV: 3530 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD37 |
|
Disorders
/ Diseases
for ANKRD37 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANKRD37 for disorders About GeneDecksing
3  diseases for ANKRD37: About MalaCardshypoxia adenocarcinoma pancreatitis
Export disorders for ANKRD37 gene to outside databases
|
Publications
for ANKRD37 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKRD37 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ANKRD37) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and characterization of a novel human gene containing 4 ankyrin repeat domains. (PubMed id 15809689)1, 2, 9 Li J....Mao Y. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- An integrative genomics approach identifies Hypoxia I nducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. (PubMed id 19491311)1 Benita Y....Xavier R.J. (2009)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ANKRD37 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ANKRD37 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKRD37 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANKRD37 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ANKRD37 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ANKRD37 gene:
Search GeneIP for patents involving ANKRD37
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANKRD37 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ANKRD37 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ANKRD37 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKRD37 | | | OriGene Protein Over-expression Lysate for ANKRD37 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ANKRD37 | | OriGene 3'-UTR Clone for ANKRD37 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD37 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ANKRD37 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ANKRD37 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ANKRD37 | | OriGene Custom Protein Services for ANKRD37 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKRD37 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD37 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD37 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKRD37 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD37 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD37 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ANKRD37 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ANKRD37 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ANKRD37 |
|  |  |  | | | | Search ThermoFisher Antibodies for ANKRD37 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ANKRD37 |
|
|
|
|
