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Aliases for ANKRD37 Gene

Aliases for ANKRD37 Gene

  • Ankyrin Repeat Domain 37 2 3 5
  • Low-Density Lipoprotein Receptor-Related Protein 2-Binding Protein 3 4
  • Low Density Lipoprotein Receptor-Related Protein Binding Protein 3
  • Ankyrin Repeat Domain-Containing Protein 37 3
  • HLrp2bp 4
  • Lrp2bp 3
  • LPR2BP 4

External Ids for ANKRD37 Gene

Previous GeneCards Identifiers for ANKRD37 Gene

  • GC04P186693
  • GC04P186554
  • GC04P186317
  • GC04P182071

Summaries for ANKRD37 Gene

GeneCards Summary for ANKRD37 Gene

ANKRD37 (Ankyrin Repeat Domain 37) is a Protein Coding gene. An important paralog of this gene is ANKRD10.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ANKRD37 Gene

Genomics for ANKRD37 Gene

Regulatory Elements for ANKRD37 Gene

Enhancers for ANKRD37 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ANKRD37 on UCSC Golden Path with GeneCards custom track

Promoters for ANKRD37 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ANKRD37 on UCSC Golden Path with GeneCards custom track

Genomic Location for ANKRD37 Gene

185,396,021 bp from pter
185,400,628 bp from pter
4,608 bases
Plus strand

Genomic View for ANKRD37 Gene

Genes around ANKRD37 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ANKRD37 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ANKRD37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ANKRD37 Gene

Proteins for ANKRD37 Gene

  • Protein details for ANKRD37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ankyrin repeat domain-containing protein 37
    Protein Accession:

    Protein attributes for ANKRD37 Gene

    158 amino acids
    Molecular mass:
    16872 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ANKRD37 Gene

Post-translational modifications for ANKRD37 Gene

  • Ubiquitination at Lys 120
  • Modification sites at PhosphoSitePlus

Other Protein References for ANKRD37 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ANKRD37 Gene

Domains & Families for ANKRD37 Gene

Gene Families for ANKRD37 Gene

Protein Domains for ANKRD37 Gene

Suggested Antigen Peptide Sequences for ANKRD37 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 ANK repeats.
  • Contains 3 ANK repeats.
genes like me logo Genes that share domains with ANKRD37: view

Function for ANKRD37 Gene

Phenotypes for ANKRD37 Gene

GenomeRNAi human phenotypes for ANKRD37:
genes like me logo Genes that share phenotypes with ANKRD37: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ANKRD37 Gene

Localization for ANKRD37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ANKRD37 Gene

Nucleus. Cytoplasm.

Subcellular locations from

Jensen Localization Image for ANKRD37 Gene COMPARTMENTS Subcellular localization image for ANKRD37 gene
Compartment Confidence
nucleus 4
cytosol 2
extracellular 2
mitochondrion 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for ANKRD37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with ANKRD37: view

Pathways & Interactions for ANKRD37 Gene

SuperPathways for ANKRD37 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ANKRD37 Gene


No data available for Pathways by source and SIGNOR curated interactions for ANKRD37 Gene

Drugs & Compounds for ANKRD37 Gene

No Compound Related Data Available

Transcripts for ANKRD37 Gene

Unigene Clusters for ANKRD37 Gene

Ankyrin repeat domain 37:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ANKRD37 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6
SP1: -
SP3: - - - -
SP4: -
SP5: -

Relevant External Links for ANKRD37 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ANKRD37 Gene

mRNA expression in normal human tissues for ANKRD37 Gene

NURSA nuclear receptor signaling pathways regulating expression of ANKRD37 Gene:


SOURCE GeneReport for Unigene cluster for ANKRD37 Gene:


mRNA Expression by UniProt/SwissProt for ANKRD37 Gene:

Tissue specificity: Mainly expressed in testis, small intestine, colon, blood leukocytes and in pancreatic adenocarcinoma cells.
genes like me logo Genes that share expression patterns with ANKRD37: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for ANKRD37 Gene

Orthologs for ANKRD37 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ANKRD37 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ANKRD37 34
  • 90.3 (n)
  • 87.97 (a)
ANKRD37 35
  • 88 (a)
(Canis familiaris)
Mammalia ANKRD37 34
  • 87.76 (n)
  • 86.08 (a)
ANKRD37 35
  • 86 (a)
(Mus musculus)
Mammalia Ankrd37 34
  • 78.9 (n)
  • 77.22 (a)
Ankrd37 16
Ankrd37 35
  • 76 (a)
(Pan troglodytes)
Mammalia ANKRD37 34
  • 98.95 (n)
  • 98.73 (a)
ANKRD37 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Ankrd37 34
  • 80.8 (n)
  • 80.38 (a)
(Monodelphis domestica)
Mammalia ANKRD37 35
  • 72 (a)
(Anolis carolinensis)
Reptilia ANKRD37 35
  • 36 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ankrd37 34
  • 64.48 (n)
  • 64.75 (a)
Str.10884 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.8033 34
(Danio rerio)
Actinopterygii ankrd37 34
  • 58.13 (n)
  • 53.6 (a)
ankrd37 35
  • 41 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 24 (a)
Species where no ortholog for ANKRD37 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ANKRD37 Gene

Gene Tree for ANKRD37 (if available)
Gene Tree for ANKRD37 (if available)

Paralogs for ANKRD37 Gene

Paralogs for ANKRD37 Gene

(1) SIMAP similar genes for ANKRD37 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ANKRD37: view

Variants for ANKRD37 Gene

Sequence variations from dbSNP and Humsavar for ANKRD37 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
VAR_048279 -
rs374245519 -- 185,398,958(+) CTCCA(C/T)TACAC reference, synonymous-codon
rs372070862 -- 185,399,031(+) TGAGT(A/G)AGTAT intron-variant
rs758218875 -- 185,399,026(+) CAAAT(-/TGAG)TGAGT splice-donor-variant
rs745394091 -- 185,398,943(+) ATGTT(C/T)TAGGA reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ANKRD37 Gene

Variant ID Type Subtype PubMed ID
esv2759309 CNV loss 17122850
esv3603492 CNV gain 21293372
esv3603493 CNV gain 21293372
nsv1033523 CNV gain 25217958
nsv428456 CNV gain+loss 18775914

Variation tolerance for ANKRD37 Gene

Residual Variation Intolerance Score: 74.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.98; 49.70% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ANKRD37 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ANKRD37 Gene

Disorders for ANKRD37 Gene

Relevant External Links for ANKRD37

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ANKRD37 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ANKRD37 Gene

Publications for ANKRD37 Gene

  1. Molecular cloning and characterization of a novel human gene containing 4 ankyrin repeat domains. (PMID: 15809689) Li J. … Mao Y. (Cell. Mol. Biol. Lett. 2005) 3 4 22 65
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  3. An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia. (PMID: 19491311) Benita Y. … Xavier R.J. (Nucleic Acids Res. 2009) 3 65
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for ANKRD37 Gene

Sources for ANKRD37 Gene