ANKRD36C Gene
protein-coding GIFtS: 31
GCID: GC02M096515
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ankyrin repeat domain 36C
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Aliases
for ANKRD36C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ankyrin Repeat Domain 36C1 2 | | Protein Immuno-Reactive With Anti-PTH Polyclonal Antibodies2 3 | | DKFZp667P09241 | | Ankyrin Repeat Domain-Containing Protein 36C2 |
Export aliases for ANKRD36C gene to outside databases |
Summaries
for ANKRD36C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ANKRD36C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NT_022171.15 NC_018913.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ANKRD36C
Other transcription factors
Search SABiosciences Chromatin IP Primers for ANKRD36C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD36C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q11.1 Ensembl cytogenetic band: 2q11.1 HGNC cytogenetic band: 2q11.1ANKRD36C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M096515: view genomic region
(about GC identifiers)
Start:
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96,514,587 bp from pter |
End:
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96,657,980 bp from pter |
Size:
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143,394 bases |
Orientation:
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minus strand |
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Proteins
for ANKRD36C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AN36C_HUMAN, Q5JPF3 (See
protein sequence)Recommended Name: Ankyrin repeat domain-containing protein 36C Size: 1778 amino acids; 199748 Da
Sequence caution: Sequence=AAB02177.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=AAB02177.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;Sequence=AAY24080.1; Type=Erroneous gene model prediction; Sequence=CAH56324.1; Type=Miscellaneous discrepancy;Note=Contaminating sequence. Potential poly-A sequence;
Secondary accessions: C9JZ08 Q15694 Q53S06 Q658V2Alternative splicing: 3 isoforms: Q5JPF3-1 Q5JPF3-2 Q5JPF3-3 Explore the universe of human proteins at neXtProt for ANKRD36C: NX_Q5JPF3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5JPF3
ANKRD36C Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000403302 ENSP00000433685 ENSP00000431824 ENSP00000415231 ENSP00000407838 ENSP00000295246
Human Recombinant Protein Products:
ANKRD36C Antibody Products:
Assay Products for ANKRD36C: |
Protein
Domains /
Families
for ANKRD36C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ANKRD36C for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5JPF3ProtoNet protein and cluster: Q5JPF3 UniProtKB/Swiss-Prot: AN36C_HUMAN, Q5JPF3Similarity: Belongs to the ANKRD36 familySimilarity: Contains 5 ANK repeats |
Function
for ANKRD36C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008200 | ion channel inhibitor activity |
NAS | 8608414 |
ANKRD36C for ontologies About GeneDecksing
|
Pathways & Interactions
for ANKRD36C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ANKRD36C
|
Drugs & Compounds
for ANKRD36C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ANKRD36C
Search CenterWatch for drugs/clinical trials and news about ANKRD36C / AN36C 
|
Transcripts
for ANKRD36C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ANKRD36C gene: NM_001010914.1 Unigene Cluster for ANKRD36C: Ankyrin repeat domain 36C Hs.646318 [show with all ESTs]Unigene Representative Sequence: AL8329778 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000456556(uc002sva.1 uc010yug.1) ENST00000488721 ENST00000531153(uc002suz.1)
ENST00000534304 ENST00000528268 ENST00000420871 ENST00000419039(uc002svb.1)
ENST00000295246(uc002svc.1)
Additional cDNA sequence: AK123626.1 AL832836.1 AL832977.1 BC038773.1 BC045568.1 U28831.1 24/27 DOTS entries (see all 27): DT.97790842 DT.100798625 DT.97844996 DT.120993148 DT.97799690 DT.452647 DT.120993079 DT.305987 DT.40257287 DT.95369247 DT.97809069 DT.102840946 DT.91774915 DT.120993081 DT.100009991 DT.120956354 DT.120993114 DT.40271857 DT.97781458 DT.97827404 DT.100027193 DT.100798632 DT.102845475 DT.91774919
GeneLoc Exon Structure
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Expression
for ANKRD36C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ANKRD36C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCTAATCAT
About this image
See ANKRD36C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ANKRD36C
SOURCE GeneReport for Unigene cluster: Hs.646318
SABiosciences Custom PCR Arrays for ANKRD36C
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ANKRD36C
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ANKRD36C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD36C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD36C |
Orthologs
for ANKRD36C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ANKRD36C gene from 3/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ANKRD626 |
Uncharacterized protein |
12(a) |
1 → many |
1(26091172-26138404) |
lizard
(Anolis carolinensis) |
Reptilia |
ANKRD626 |
-- |
35(a) |
1 → many |
GL344195.1(39104-48393) |
zebrafish
(Danio rerio) |
Actinopterygii |
si:ch211-272n13.36 |
si:ch211-272n13.3 |
5(a) |
1 → many |
25(3581527-3655709) |
ENSEMBL Gene Tree for ANKRD36C (if available)
TreeFam Gene Tree for ANKRD36C (if available) |
Paralogs
for ANKRD36C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ANKRD36C gene
- POTEF2 POTEI2 ANKRD30A2 ANKRD362 ANKRD72 POTEB2 ANKRD30BL2 ANKRD20A32
- POTEH2 ENSG000001552822 ANKRD30B2 ENSG000002663022 POTEJ2 POTEC2 ANKRD20A22 POTEG2
- ANKRD262 ANKRD622 ANKRD18A2 ENSG000001882192 POTEM2 ANKRD20A12 LOC1009963312 CCDC144A2
- POTED2 ANKRD20A42 ANKRD18B2 LOC1002889662
18/24 SIMAP similar genes for ANKRD36C using alignment to 7 protein entries: AN36C_HUMAN (see all proteins)
(see all similar genes):ANKRD36B ANKRD36 ANKRD36BP1 ANKRD20A5P ANKRD19P ANKRD30BL
LOC254750 ANKRD26P1 ANKRD7 POTEF DKFZp781D1722 ANKRD62
POTEC POTEB POTEG POTEH POTEM MGC26718
ANKRD36C for paralogs About GeneDecksing
5/7 Pseudogenes.org Pseudogenes for ANKRD36C (see all 7)
PGOHUM00000249940 PGOHUM00000240724 PGOHUM00000237656 PGOHUM00000235172 PGOHUM00000260172
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Genomic Variants
for ANKRD36C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ANKRD36C (96514587 - 96657980 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ANKRD36C: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD36C |
|
Disorders
/ Diseases
for ANKRD36C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ANKRD36C for disorders About GeneDecksing
2  diseases for ANKRD36C: About MalaCardsosteomalacia uremia
Export disorders for ANKRD36C gene to outside databases
|
Publications
for ANKRD36C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ANKRD36C gene integrated from 9 sources:
(articles sorted by number of sources associating them with ANKRD36C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Inhibitors of renal epithelial phosphate transport in tumor-induced osteomalacia and uremia. (PubMed id 8608414)1, 2 Kumar R.... Cai Q. (1995)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
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External Searches for ANKRD36C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ANKRD36C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ANKRD36C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ANKRD36C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ANKRD36C gene:
Search GeneIP for patents involving ANKRD36C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ANKRD36C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ANKRD36C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ANKRD36C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ANKRD36C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ANKRD36C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ANKRD36C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ANKRD36C |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for ANKRD36C |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ANKRD36C |
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